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CompletedNCT04084262Updated Sep 23, 2022

Multi-Plane Hallux Valgus Correction With the Phantom® Nail

An observational study in Arthrodesis, Bunion and Hallux Valgus, sponsored by Paragon 28. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-09-23.

Sponsored by Paragon 28 · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
12
Ages
18 Years and older
Sex
All
01

Study summary

The goal of this research study is to determine the change in frontal plane rotation of the 1st metatarsal from pre to post arthrodesis of the 1st TMT joint with the Phantom® Intramedullary Nail combined with a supinating reduction technique.

The study hypothesis is that multi-planar correction can be achieved with the Phantom® Intramedullary Nail.

Read the detailed description

Each subject will undergo a Lapidus Arthrodesis combined with a supinating reduction technique.

The subjects will undergo 3 weight-bearing CBCT scans of their foot and ankle, one pre-arthrodesis, one two weeks post-arthrodesis, and one 12 weeks post-arthrodesis. These scans will be used to determine change in frontal plane rotation of the 1st metatarsal from pre to post arthrodesis of the 1st TMT joint, change in angular/positional alignment of the 1st TMT joint using various measurements (1-2 IMA, Meary's Angle, HVA, MAA, Sesamoid Position, and Sesamoid Frontal Plane Rotation), maintenance of correction of the 1st TMT joint, and union status.

The subjects will also complete three surveys, the Pain and Satisfaction Survey, the AOFAS Hallux MTP-IP Scale, and the FAOS Foot and Ankle Survey, at the Pre-Operative Visit, 2 Week Visit (post-op), 6 Week Visit (post-op), and 12 Week Visit (post-op). Furthermore, the subjects will be asked about their willingness to undergo the procedure again at the 12 Week Visit (post-op). All of these scores will be considered in the secondary objectives.

Aside from the study activities listed above, all procedures, visits, and instructions for the subject are to follow the standard of care.

02

Conditions studied

  • Arthrodesis
  • Bunion
  • Hallux Valgus

Keywords

  • bunion
  • supinating reduction
  • multi-plane
  • lapidus
  • arthrodesis
  • intramedullary nail
  • hallux valgus
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

The study population will consist of adults age 18 and older with a hallux valgus deformity. The most common age demographic to have surgery for hallux valgus correction is age 50-59. Additionally, the prevalence of hallux valgus in females is greater than males, so a higher percentage of female subjects seeking treatment is likely to be expected.

Inclusion criteria

  • The subject is at least 18 years of age at the time of screening.
  • The subject has been diagnosed with hallux valgus.
  • The subject has pain associated with hallux valgus.
  • The subject agrees to comply with the requirements of the study and complete the study measures.
  • The subject is willing and able to provide written informed consent.
  • The subject plans to undergo a Lapidus Arthrodesis procedure with a 3-Hole Phantom® Intramedullary Nail.

Exclusion criteria

Exclusion Criteria:

  • The subject is pregnant.
  • The subject has had previous surgery for hallux valgus on operative side.
  • The subject will require a structural graft in the 1st TMT joint.
  • The unshod foot in question is greater than 28 cm in length.
  • The subject is not expected to complete the study according to the investigation plan.
  • The subject has been deemed physiologically or psychologically inadequate by the enrolling physician.
  • The subject is a prisoner, unable to understand what participation in the study entails, mentally incompetent, a known abuser of alcohol and/or drugs, or anticipated to be non-compliant.
04

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
12 participants (actual)
Patient registry
No

Groups and cohorts

  • All Study Participants

    Phantom® Intramedullary Nail combined with a supinating reduction technique

    Device: Intramedullary Nail

Interventions

  • DeviceIntramedullary Nail

    Subjects undergo a Lapidus Arthrodesis procedure combined with a supinating reduction technique to create a multi-plane correction of hallux valgus

    Also known as: Phantom® Intramedullary Nail

05

What researchers measure

Primary outcomes

  1. Change in Frontal Plane Rotation

    Determine the change in frontal plane rotation of the 1st metatarsal from pre to post arthrodesis of the 1st tarsometatarsal joint with the Phantom® Intramedullary Nail combined with a supinating reduction technique.

    Time frame: 12 weeks

Secondary outcomes

  1. 1-2 Inter Metatarsal Angle

    Change in 1-2 Inter Metatarsal Angle before and after arthrodesis of the 1st tarsometatarsal joint using weightbearing CBCT imaging

    Time frame: Pre-op, 2 weeks, 12 weeks

  2. Meary's Angle

    Change in Meary's Angle before and after arthrodesis of the 1st tarsometatarsal joint using weightbearing CBCT imaging

    Time frame: Pre-op, 2 weeks, 12 weeks

  3. Hallux Valgus Angle

    Change in Hallux Valgus Angle before and after arthrodesis of the 1st tarsometatarsal joint using weightbearing CBCT imaging

    Time frame: Pre-op, 2 weeks, 12 weeks

  4. Metatarsus Adductus Angle

    Change in Metatarsus Adductus Angle before and after arthrodesis of the 1st tarsometatarsal joint using weightbearing CBCT imaging

    Time frame: Pre-op, 2 weeks, 12 weeks

  5. Sesamoid Position

    Change in sesamoid position before and after arthrodesis of the 1st tarsometatarsal joint using weightbearing CBCT imaging

    Time frame: Pre-op, 2 weeks, 12 weeks

  6. Sesamoid Frontal Plane Rotation

    Change in sesamoid frontal plane rotation before and after arthrodesis of the 1st tarsometatarsal joint using weightbearing CBCT imaging

    Time frame: Pre-op, 2 weeks, 12 weeks

  7. Maintenance of Correction

    Maintenance of lapidus arthrodesis correction via CBCT analysis

    Time frame: Pre-op, 2 weeks, 12 weeks

  8. Union Status

    Union/delayed union status at 12 Week Visit

    Time frame: 12 weeks

  9. Clinical Complications

    Any lapidus arthrodesis related clinical complications

    Time frame: Pre-Op, 2 weeks, 6 weeks,12 weeks

  10. Patient Current Level of Pain at Surgical Site

    Visual Analog Scale (VAS). Line from 0 (no pain) to 10 (worst pain). Patient reported.

    Time frame: Pre-Op, 2 weeks, 6 weeks, 12 weeks

  11. AOFAS

    Change in AOFAS Hallux Metatarsophalangeal-Interphalangeal Scale scores AOFAS Hallux Metatarsophalangeal-Interphalangeal Scale foot clinical score. Pain: 0-40 points Function: 0-45 points Alignment: 0-15 points Total Score (sum): 0-100 points (higher score indicates better outcomes)

    Time frame: Pre-Op, 2 weeks, 6 weeks, 12 weeks

  12. FAOS

    Change in FAOS Foot and Ankle Survey scores Standardized answer options are given (% Likert boxes) and each question gets a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale. Subscales: Pain Other Symptoms Functions in Daily Living (ADL) Function in sport and recreation Foot and ankle-related Quality of Life (QoL)

    Time frame: Pre-Op, 2 weeks, 6 weeks, 12 weeks

  13. Patient Satisfaction with Procedure

    Patient reported satisfaction by check boxes (Likert Scale) from Pain and Satisfaction Survey

    Time frame: Pre-Op, 2 weeks, 6 weeks, 12 weeks

  14. Willingness to Undergo Procedure Again

    Willingness to undergo procedure again (Yes/No)

    Time frame: 12 weeks

06

Study locations

1 site
  • Orthopedic Center of Palm Beach County
    Atlantis, Florida 33462, United States
07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT04084262
Lead sponsor
Paragon 28
Responsible party
Sponsor
First posted
Sep 10, 2019
Start date
Nov 7, 2019
Primary completion
Apr 1, 2022
Completion
May 9, 2022
Last update
Sep 23, 2022

Study contacts

Laura Brinker, DPM
study director · Director of Clinical Research

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

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