Drug
Poractant alfa clinical trials
Also written Curosurf.
Keep track of what changes. Save the poractant alfa studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
19 studies that test it; most in 2021 (4)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2007 | 1 |
| 2009 | 2 |
| 2010 | 1 |
| 2011 | 1 |
| 2012 | 1 |
| 2013 | 2 |
| 2019 | 1 |
| 2020 | 2 |
| 2021 | 4 |
| 2024 | 1 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 17
Chiesi Farmaceutici S.p.A. (2) · Dr. Sami Ulus Children's Hospital (2) · University of Michigan (2) · Jean Michel Hascoet (1) · University of Missouri-Columbia (1) · Zekai Tahir Burak Women's Health Research and Education Hospital (1) · University of Cologne (1) · Hospital Clinic of Barcelona (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses poractant alfa is read from its arms, and is right about nine times in ten.
Testing it · 19
- Duration of Surfactant Administration and Impact on Stabilisation of Vital Parameters in Very Preterm Neonates: 1 Minutes Versus 5 MinutesRecruitingPhase 4Medical University of GrazNCT07261787Written as Poractant alfa (Curosurf®) - 1-minute administration
- Calfactant vs Poractant Alfa Using a Less Invasive Technique in Preterm Infants With Respiratory Distress SyndromeRecruitingPhase 4Uludag UniversityNCT07350018Written as Poractant alfa
- Prophylactic Minimally Invasive Surfactant EvaluationRecruitingPhase 4Endeavor HealthNCT06007547Written as Poractant Alfa
- Intratracheal Budesonide With Surfactant to Prevent Bronchopulmmonary Dysplasia.Not yet recruitingPhase 3Hospital Clinic of BarcelonaNCT04862377Written as Poractant Alfa Intratracheal Suspension [Curosurf]
- Medium vs Low Oxygen Threshold for the Surfactant AdministrationNot yet recruitingPhase 4Virgilio Paolo CarnielliNCT04199364Written as Poractant Alfa 80 mg/mL Intratracheal Suspension
- Cold Heart Study: A Randomized Pilot Trial of Surfactant TherapyTerminatedPhase 1University of MichiganNCT04181255Written as Curosurf
- Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS)TerminatedPhase 2Chiesi Farmaceutici S.p.A.NCT04502433Written as CUROSURF® (poractant alfa)
- Exogenous Surfactant in Very Preterm Neonates in Prevention of Bronchopulmonary DysplasiaCompletedPhase 4Jean Michel HascoetNCT01039285Written as Curosurf
- Late Surfactant After a Recruitment Maneuver in Extremely Low Gestational Age Newborns - LATE-REC-SURF TrialStatus unknownPhase 2VENTO GIOVANNINCT04825197Written as Poractant Alfa Intratracheal Suspension [Curosurf]
- Efficacy and Safety of Curosurf® in Patients Invasively Ventilated for Severe Bronchiolitis Under 12 Months of AgeTerminatedPhase 3Azienda Ospedaliera Universitaria Integrata VeronaNCT03959384Written as Curosurf 80Mg/Ml Intratracheal Suspension
- Curosurf® in Adult Acute Respiratory Distress Syndrome Due to COVID-19Status unknownPhase 2Dr Christophe LENCLUDNCT04384731Written as poractant alfa
- Efficacy of Combining Prophylactic Curosurf With Early Nasal CPAP in Delivery Room: the Curpap StudyCompletedPhase 4Chiesi Farmaceutici S.p.A.NCT00501982Written as Poractant alfa (Curosurf®)
- Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress SyndromeCompletedNot applicableUniversity of Missouri-ColumbiaNCT02834624Written as Poractant alfa
- Lung Lavage With Dilute Poractant Alfa for Meconium Aspiration SyndromeCompletedPhase 4Zekai Tahir Burak Women's Health Research and Education HospitalNCT02041546Written as Lung lavage with surfactant
- Comparison in Pulmonary Compliance Between Curosurf and Survanta in Preterm Infants With Respiratory Distress SyndromeWithdrawnNot applicableUniversity of MichiganNCT01537354Written as Curosurf®
- Comparison of Two Different Natural Surfactants in the Treatment of Pulmonary HemorrhageCompletedNot applicableDr. Sami Ulus Children's HospitalNCT01860014Written as Poractant alfa
- Perfusion Index Variability in Respiratory Distress SyndromeCompletedNot applicableDr. Sami Ulus Children's HospitalNCT01852461Written as Poractant alfa
- Surfactant Application During Spontaneous Breathing With Continuous Positive Airway Pressure (CPAP) in Premature Infants < 27 WeeksCompletedNot applicableUniversity of CologneNCT00751959Written as Curosurf
- Curosurf and Survanta Treatment(CAST)of RDS in Very Premature InfantsTerminatedPhase 4Alan FujiiNCT00767039Written as Curosurf (poractant)
Given in every arm · 2 — poractant alfa is usual care beside what is tested
- Efficacy of Adding Budesonide to Poractant Alfa to Prevent Bronchopulmonary Dysplasia.Status unknownPhase 4Hospital Central "Dr. Ignacio Morones Prieto"NCT03521063Written as Poractant Alfa
- Efficacy of a New Technique -"IN-REC-SUR-E"- in Preterm Neonates With RDSCompletedNot applicableCatholic University of the Sacred HeartNCT02482766Written as Poractant alfa, 200 mg/kg
As the comparator · 1 — what is tested is compared with poractant alfa
Codes
What other systems call poractant alfa · ClinicalTrials.gg INT003561
- MeSH (NLM) C068291poractant alfaConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) KE3U2023NPPORACTANT ALFAConfirmed FDA, NLM, Wikidata
- RxNorm 236381Confirmed FDA, Wikidata
- Wikidata Q15708403poractant alfaConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C81353Poractant AlfaConfirmed FDA, Wikidata
- DrugBank DB09113One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C068291 | poractant alfa | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | KE3U2023NP | PORACTANT ALFA | Confirmed FDA, NLM, Wikidata |
| RxNorm | 236381 | — | Confirmed FDA, Wikidata |
| Wikidata | Q15708403 | poractant alfa | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C81353 | Poractant Alfa | Confirmed FDA, Wikidata |
| DrugBank | DB09113 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.