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Graves Disease clinical trials

The registry lists 162 studies for Graves Disease across more than 10 countries. 53 are recruiting or about to start. 99 of them are mainly about Graves Disease (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-04. Counting its narrower condition Graves Ophthalmopathy too: 325 studies, 104 open.

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Status

Completed
74
Recruiting
39
Status unknown
18
Not yet recruiting
11
Active, not recruiting
8
Terminated
5

Phase

Phase 2
26
Phase 3
18
Phase 4
15
Phase 1
13
Early Phase 1
3

Where

United States
43
China
19
United Kingdom
15
Italy
14
Poland
12
Spain
12

Who runs them

The University of Hong Kong (4) · Vastra Gotaland Region (4) · Assiut University (4) · National Taiwan University Hospital (4) · Medical University of Warsaw (4) · Viridian Therapeutics, Inc. (4) · Immunovant Sciences GmbH (4) · Mayo Clinic (4)

What is being tested here

Drugs under test in Graves Disease studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Imeroprubart303
BHV-1300323
Efgartigimod alfa222
Hyaluronidase (human recombinant)222
Methimazole114
Dexamethasone102
Atorvastatin101
Rilzabrutinib101
Felzartamab101
Linsitinib111

Drug classes tested here Antithyroid drugs 1 open · Corticosteroids 1 open

Coming up

6phase 3 studies under way
14studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 39 Graves Disease studies recruiting now, 17 (44%) set no upper age limit and 20 (51%) stop at 75 or younger. 3 (8%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 7 (18%) take healthy volunteers.

Recruiting studies that take each age, of 39
AgeWomenMen
102 (5%)2 (5%)
1838 (97%)38 (97%)
3038 (97%)38 (97%)
4038 (97%)38 (97%)
5038 (97%)38 (97%)
6537 (95%)37 (95%)
7527 (69%)27 (69%)
8519 (49%)19 (49%)

Across all 162 studies, recruiting or not: 48% stop at 75 or younger and 27% at 65; 14% take children; 2% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Graves Disease studies take

Of 22 interventional studies with no phase under Graves Disease, half reached primary completion within 47 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase47 mo35–88 · 22 studies——
Observational48 mo19–118 · 18 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

Stopped1

Newly registered5

Studies

Recruiting first, then most recently updated. Showing 50 of 162. Browse all 162 → or search them.