Asphyxia Neonatorum clinical trials
The registry lists 106 studies for Asphyxia Neonatorum across more than 10 countries. 19 are recruiting or about to start. 65 of them are mainly about Asphyxia Neonatorum (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Who runs them
Imperial College London (5) · Sharp HealthCare (4) · Aga Khan University (3) · University of California, San Francisco (3) · Nemours Children's Clinic (3) · University of Alberta (3) · NICHD Global Network for Women's and Children's Health (3) · Pia Wintermark (2)
What is being tested here
Drugs under test in Asphyxia Neonatorum studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 7, phase 3 first
- Dec 2026A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic Hypothermia · Phase 3 · ReAlta Life Sciences, Inc.
- Nov 2026Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic Encephalopathy · Pharmazz, Inc.
- Dec 2026Is Feeding During Therapeutic Hypothermia Safe and Can Improve Outcomes in Infants With Hypoxic-ischaemic Encephalopathy · Nutricia Foundation
- Jul 2027Advanced Wireless Sensors for Neonatal Care in the Delivery Room · Guilherme Sant'Anna, MD
- Aug 2027Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow Up · Nemours Children's Clinic
- Aug 2027Effectiveness of Simulation-based Training Delivered to Special Newborn Care Providers on Resuscitation Management and Kangaroo Mother Care: Simulation-based Training for Asyphxia in Babies Trial (STAR-Baby Trial) · Integrated Development Foundation Nepal
- Nov 2027Sustained Cord Circulation at Emergency Cesarean Section · Region Skane
Who these studies take
Of the 15 Asphyxia Neonatorum studies recruiting now, 3 (20%) set no upper age limit and 12 (80%) stop at 75 or younger. 15 (100%) take children under 18. 2 (13%) are for women only and 0 (0%) for men only; 2 (13%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (20%) | 1 (7%) |
| 18 | 3 (20%) | 1 (7%) |
| 30 | 3 (20%) | 1 (7%) |
| 40 | 3 (20%) | 1 (7%) |
| 50 | 3 (20%) | 1 (7%) |
| 65 | 3 (20%) | 1 (7%) |
| 75 | 3 (20%) | 1 (7%) |
| 85 | 3 (20%) | 1 (7%) |
Across all 106 studies, recruiting or not: 75% stop at 75 or younger and 75% at 65; 87% take children; 13% are for women only and 0% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Asphyxia Neonatorum studies take
Of 33 interventional studies with no phase under Asphyxia Neonatorum, half reached primary completion within 15 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 15 mo8–34 · 33 studies | — | 15 mo8–34 · 33 studies |
| Observational | 32 mo14–47 · 16 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Results posted1
- Delayed Cord Clamping With Oxygen In Extremely Low Gestation InfantsOct 15, 2026NCT04413097
Studies
Recruiting first, then most recently updated. Showing 50 of 106. Browse all 106 → or search them.
- A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RLS-0071 in Newborns With Moderate or Severe Hypoxic-Ischemic Encephalopathy Undergoing Therapeutic HypothermiaRecruitingNCT05778188Phase 2/31 country
- Sustained Cord Circulation at Emergency Cesarean SectionRecruitingNCT06540222Not applicable1 country
- Treatment of Neonatal Encephalopathy With Oral Sildenafil Suspension to Repair Brain Injury Secondary to Birth AsphyxiaRecruitingNCT06098833Phase 22 countries
- Evaluation of Neonatal Acute Hypoxia at Delivery Using Fetal Physiology and Eucapnic pH AssessmentNot yet recruitingNCT076292711 country
- Effectiveness of Simulation-based Training Delivered to Special Newborn Care Providers on Resuscitation Management and Kangaroo Mother Care: Simulation-based Training for Asyphxia in Babies Trial (STAR-Baby Trial)Not yet recruitingNCT07574944Not applicable
- Advanced Wireless Sensors for Neonatal Care in the Delivery RoomRecruitingNCT06693817Not applicable4 countries
- Cooling in Mild EncephalopathyRecruitingNCT05889507Phase 32 countries
- Hypoxia Profiles Identified in Term Newborns With Cord pH <7.00RecruitingNCT073335991 country
- Assess Safety and Efficacy of Sovateltide in Hypoxic-ischemic EncephalopathyRecruitingNCT05514340Phase 21 country
- Swiss Neonatal Network & Follow-up GroupRecruitingNCT042395081 country
- Face Mask vs Laryngeal Mask in Neonatal ResuscitationNot yet recruitingNCT06952088Not applicable1 country
- Impact of Maternal Body Mass Index on Infant Hypoxic Events at Time of Delivery ,Cross-sectional Study.Not yet recruitingNCT06917833
- Fetal Assessment of the Myocardium and Evaluation of the NeonateRecruitingNCT061869731 country
- Functional Imaging of Baby BrainsRecruitingNCT055146651 country
- Evaluation of Maternal & Newborn Health Simulation Lab Centers of Excellence in NepalRecruitingNCT06577922Not applicable1 country
- Is Feeding During Therapeutic Hypothermia Safe and Can Improve Outcomes in Infants With Hypoxic-ischaemic EncephalopathyRecruitingNCT06394453Not applicable1 country
- Erythropoietin for Neonatal Encephalopathy in LMIC (EMBRACE Trial)RecruitingNCT05395195Phase 33 countries
- Nutrition Optimalization Among Pregnant Women to Improve Maternal and Neonatal Outcome in DKI JakartaRecruitingNCT06268509Not applicable1 country
- Citicoline as Neuroprotector in Neonates Exposed to HypoxiaRecruitingNCT03949049Phase 31 country
- Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced KountriesCompletedNCT03657394Not applicable1 country
- Delayed Cord Clamping With Oxygen In Extremely Low Gestation InfantsActive, not recruitingNCT04413097Not applicable1 country
- Finding Solutions to Thrive After Birth Asphyxia in AfricaCompletedNCT05275725Phase 11 country
- Sildenafil to Repair Brain Injury Secondary to Birth AsphyxiaCompletedNCT04169191Phase 11 country
- Renal and Cerebral NIRS and Early Acute Kidney Injury in Cooled Neonates With Birth AsphyxiaCompletedNCT077430991 country
- Comparative Outcomes Related to Delivery-room Cord Milking In Low-resourced Kountries Developmental Follow UpActive, not recruitingNCT03682042Not applicable1 country
- Success of Laryngeal Mask Airway (LMA) Insertion During Continuous Chest Compressions in Neonatal Resuscitation: A Randomized Crossover Simulation StudyCompletedNCT07681960Not applicable1 country
- Cluster Randomized Controlled Trial Applying Helping Baby Breathe in NepalCompletedNCT06213207Not applicable1 country
- Augmented Infant Resuscitator (AIR): Transitioning a Novel Behavior Change Innovation to Drive Newborn Ventilation Skills EnhancementCompletedNCT05349175Not applicable1 country
- Neuroprotective Efficacy of Postnatal Magnesium Sulphate in Term Infants With Birth AsphyxiaCompletedNCT05707962Not applicable1 country
- Intrapartum Sildenafil in Laboring MothersWithdrawnNCT06377098Phase 33 countries
- Oral Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource SettingsWithdrawnNCT06522854Phase 31 country
- Cell-Based Therapy for White Matter Repair in Periventricular LeukomalaciaWithdrawnNCT06985303Early Phase 1
- Echocardiography Sub-Study of the Umbilical Cord Milking in Non-Vigorous Infants Trial (MINVI)CompletedNCT03798093Not applicable1 country
- Effects of Delayed Cord Clamping During Resuscitation of Newborn Near Term and Term InfantsActive, not recruitingNCT04070560Not applicable1 country
- Non-Invasive Neurally Adjusted Ventilatory Assist (NAVA) Prone vs Supine in Premature InfantsCompletedNCT05968586Not applicable1 country
- Comparison of Visual Instructions for Inserting a Laryngeal Mask in a Neonatal Mannequin.CompletedNCT06502327Not applicable1 country
- Comparison of Virtual Training to In-Person Training of Helping Babies Breathe in EthiopiaCompletedNCT05854745Not applicable1 country
- Perinatal Conditions Influencing Morbidity, Mortality, and Medical Care in NewbornsCompletedNCT066533741 country
- Heart Rate Assessment at Birth Comparing Stethoscope Versus Tap-based ApplicationWithdrawnNCT03913533Not applicable1 country
- Umbilical Cord Milking in Non-Vigorous InfantsCompletedNCT03631940Not applicable3 countries
- SI + CC Versus 3:1 C:V Ratio During Neonatal CPRCompletedNCT02858583Not applicable2 countries
- Enhancing Neonatal Sucking Reflex: A Study on the Efficacy of Magnesium Sulphate in Severe Birth AsphyxiaCompletedNCT06468475Not applicable1 country
- Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth.CompletedNCT064291111 country
- Sildenafil Citrate to Improve Maternal and Neonatal Outcomes in Low-resource SettingsCompletedNCT059466811 country
- Heart Beat Variability in Neonatal EncephalopathyActive, not recruitingNCT031795531 country
- The Baby-Saver Kit: Clinical Testing of a Device for Neonatal Resuscitation With Intact Cord in UgandaTerminatedNCT038854921 country
- Optimising Newborn Nutrition During Therapeutic Hypothermia.CompletedNCT032788471 country
- Passive Cooling Versus Blanket-Roll III on The Myocardial Function of Asphyxiated NeonatesCompletedNCT05652738Not applicable1 country
- Umbilical Cord Milking in Neonates Who Are Depressed at Birth-Developmental Follow Up (MIDAB-FU)WithdrawnNCT03681314Not applicable1 country
- Resident Training Enhanced by New Innovations: TeleintubationCompletedNCT02572427Not applicable