An interventional study of Umbilical Cord Milking in Hypoxic-Ischemic Encephalopathy and Birth Asphyxia, sponsored by Nemours Children's Clinic. Withdrawn at 3 sites in India. Open to participants aged 3 Months to 26 Months. Per ClinicalTrials.gov, last updated 2023-04-25.
Sponsored by Nemours Children's Clinic · Not applicable, Interventional, and Supportive care
An extension of the MIDAB trial, the MIDAB-Follow-up trial will evaluate the neurodevelopmental outcomes at 22-26 months age of term/late preterm infants who were depressed at birth and received umbilical cord milking (UCM) or immediate cord clamping (ICC).
The MIDAB-Follow-up trial will examine the difference in survival and neurodevelopmental impairment of infants who were depressed at birth and enrolled in MIDAB trial. The difference in survival and neurodevelopmental impairment in infants who received UCM and ICC will be assessed using standardized neurological and developmental assessment tools at 22-26 months of age.
261 studies on the registry are indexed under Hypoxia-Ischemia, Brain; 95 are open to participants now.
Browse Hypoxia-Ischemia, Brain studies →Nemours Children's Clinic is the lead sponsor of 130 studies on the registry; 26 are open to participants now.
Of its 9 completed or terminated interventional studies of FDA-regulated products, 6 (67%) have results posted.
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Exclusion Criteria:
At delivery, the umbilical cord is grasped, and blood is pushed toward the infant 4 times before the cord is clamped. This procedure infuses a placental transfusion of blood into the infant and can be done in 10-15 seconds.
Other: Umbilical Cord Milking
The umbilical cord is clamped immediately after the delivery.
At delivery, the umbilical cord is grasped, and blood is pushed toward the infant 4 times before the cord is clamped. This procedure infuses a placental transfusion of blood into the infant and can be done in 10-15 seconds.
Neurodevelopmental Outcome at 2 Years of Age
Overall and Domain Scores - Ages and Stages, 3rd ed. Questionnaire
Time frame: 22-26 months
Fidgety Movements at 3 months of age
Assessment of Fidgety Movements by Prechtl's method
Time frame: 3-5 months
Neurodevelopmental Outcome at 1 Year of Age
Developmental Activities Screening Inventory - Second Edition (DASI-II)
Time frame: 10-14 months
Autism Outcome
Modified Checklist for Autism in Toddlers (M-CHAT-R)
Time frame: 22-26 months
Plan to share: Undecided
No publications or documents are linked to this record.
Started Oct 2022 (actual). Primary completion is estimated for Jun 2024, 19 months after the start.
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This study is withdrawn, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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