Apraxias clinical trials
The registry lists 65 studies for Apraxias across more than 10 countries. 21 are recruiting or about to start. 24 of them are mainly about Apraxias (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-27.
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Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
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· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Who runs them
Mayo Clinic (4) · VA Office of Research and Development (4) · New York University (3) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · Aline Mara de Oliveira (2) · Universidad de Granada (2) · Georgetown University (2) · MGH Institute of Health Professions (2)
What is being tested here
Drugs under test in Apraxias studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Flortaucipir | 1 | 0 | 1 |
| Methylphenidate | 0 | 0 | 1 |
| Pittsburgh compound B | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 9
- Dec 2026Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of Speech · Karolinska Institutet
- Jan 2027taVNS for Speech and Language Recovery in Aphasia · University of Florida
- Apr 2027Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain Stimulation · The University of Texas at Dallas
- Apr 2027Using tDCS in Speech-based Stroke Rehabilitation · NYU Langone Health
- Jul 2027The Neurobiology of Two Distinct Types of Progressive Apraxia of Speech · Mayo Clinic
- Jul 2027Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CAS · 4th Military Clinical Hospital with Polyclinic, Poland
- Oct 2027Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in Children · Aline Mara de Oliveira
- Oct 2027Feasibility and Preliminary Effects of a Therapeutic Approach Using Ultrasound Visual Biofeedback in Children With AFI: a Pilot Randomized Clinical Trial. · Aline Mara de Oliveira
- Nov 2027Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia · Stephanie Grasso
Who these studies take
Of the 14 Apraxias studies recruiting now, 5 (36%) set no upper age limit and 7 (50%) stop at 75 or younger. 6 (43%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (14%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (36%) | 5 (36%) |
| 18 | 8 (57%) | 8 (57%) |
| 30 | 7 (50%) | 7 (50%) |
| 40 | 8 (57%) | 8 (57%) |
| 50 | 8 (57%) | 8 (57%) |
| 65 | 8 (57%) | 8 (57%) |
| 75 | 8 (57%) | 8 (57%) |
| 85 | 7 (50%) | 7 (50%) |
Across all 65 studies, recruiting or not: 43% stop at 75 or younger and 38% at 65; 38% take children; 0% are for women only and 0% for men only; 23% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Apraxias studies take
Of 30 interventional studies with no phase under Apraxias, half reached primary completion within 53 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 53 mo21–59 · 30 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 65. Browse all 65 → or search them.
- Feasibility and Preliminary Effects of a Therapeutic Approach Using Ultrasound Visual Biofeedback in Children With AFI: a Pilot Randomized Clinical Trial.RecruitingNCT07087249Not applicable1 country
- Expanded Access Protocol: Umbilical Cord Blood Infusions for Children With Brain InjuriesAvailableNCT033274671 country
- Deep Brain Stimulation + Therapy for StrokeNot yet recruitingNCT07849114Not applicable1 country
- Motor-based Intervention for Childhood Apraxia of Speech: DTTC-ConnectRecruitingNCT07526246Not applicable1 country
- Speech Therapy for Children With Rare Genetic Conditions and Childhood Apraxia of SpeechRecruitingNCT07815249Not applicable1 country
- Role of Omega-DEK in Childhood Apraxia of SpeechNot yet recruitingNCT07216001Phase 21 country
- Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive AphasiaRecruitingNCT05741853Not applicable2 countries
- Using tDCS in Speech-based Stroke RehabilitationRecruitingNCT03452202Not applicable1 country
- taVNS for Speech and Language Recovery in AphasiaEnrolling by invitationNCT07563387Not applicable1 country
- The Neurobiology of Two Distinct Types of Progressive Apraxia of SpeechRecruitingNCT033130111 country
- Speech Treatment for Minimally Verbal Children With ASD and CASRecruitingNCT05066178Not applicable1 country
- Clinico-Pathologic-Genetic-Imaging Study of Neurodegenerative and Related DisordersEnrolling by invitationNCT046801301 country
- Longitudinal Multi-Modality Imaging in Progressive Apraxia of SpeechRecruitingNCT01818661Phase 41 country
- Endarterectomy Versus Stenting in Patients With Symptomatic Severe Carotid Stenosis - 2RecruitingNCT07054060Not applicable1 country
- Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of SpeechRecruitingNCT06467136Not applicable1 country
- Measuring Aided Language DevelopmentRecruitingNCT06512168Not applicable1 country
- ReadMap: Reading in Stroke Alexia and Typical AgingRecruitingNCT067000051 country
- Changes in Neuroplasticity Following Intensive Rehabilitation of Aphasia and/or Apraxia of SpeechRecruitingNCT04604444Not applicable1 country
- Treatment of Cantonese Speakers With Childhood Apraxia of SpeechRecruitingNCT06385470Not applicable1 country
- Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CASNot yet recruitingNCT06123767Not applicable1 country
- Effects of a Multimodal Exercise Program for Children With ASDNot yet recruitingNCT05509231Not applicable
- A Randomized Control Trial of Motor-based Intervention for CASActive, not recruitingNCT04642053Not applicable1 country
- Methylphenidate in Childhood Apraxia of SpeechCompletedNCT05185583Phase 21 country
- Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in ChildrenActive, not recruitingNCT07636031Not applicable1 country
- The Effects of Caregiver Training on DTTC Treatment Outcomes in CASActive, not recruitingNCT05916222Not applicable1 country
- ASSIST: Treatment for Childhood Apraxia of SpeechCompletedNCT03903120Phase 11 country
- Treating Primary Progressive Aphasia and Apraxia of Speech Using Non-invasive Brain StimulationActive, not recruitingNCT05368350Not applicable1 country
- Apraxia in Parkinson's Disease Patients With Deep Brain StimulationTerminatedNCT047257731 country
- Dose Frequency RCT on DTTC in Children With CASActive, not recruitingNCT05675306Not applicable1 country
- Investigating the Effects of Rhythm and Entrainment on Fluency in People With AphasiaCompletedNCT05248295Not applicable1 country
- Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural NetworksCompletedNCT031533711 country
- Effects of tDCS on Apraxia of Speech in Non-Fluent Primary Progressive AphasiaWithdrawnNCT04486586Not applicable1 country
- Brain-based Understanding of Individual Language Differences After StrokeActive, not recruitingNCT049915191 country
- The Effect of Social Skills Intervention on Praxis and Social Functioning in Individuals With SchizophreniaCompletedNCT05901922Not applicable1 country
- Childhood Apraxia of Speech: Experience Dependent Changes Induced by TreatmentCompletedNCT048325031 country
- Treating Childhood Apraxia of SpeechCompletedNCT03238677Not applicable1 country
- Video Assisted Speech Technology to Enhance Motor Planning for SpeechCompletedNCT04764539Not applicable1 country
- MIRAA - Implementation of Intensive Rehabilitation of Aphasia and/or Apraxia of Speech in Swedish HealthcareCompletedNCT04957225Not applicable1 country
- Searching of Apraxia of Speech in Children With Specific Language ImpairmentStatus unknownNCT055840331 country
- tDCS and Speech Therapy for Motor Speech Disorders Caused by FTLD Syndromes: a Feasibility StudyWithdrawnNCT04883229Not applicable
- Treatment Intensity - Apraxia of SpeechCompletedNCT02332915Not applicable1 country
- Rehabilitating (Stroke-induced) Apraxia With Direct Current StimulationCompletedNCT03185234Not applicable1 country
- Efficacy of START (Startle Rehabilitation Therapy) in the Treatment Stroke-induced Aphasia/ApraxiaStatus unknownNCT04816799Early Phase 11 country
- Apraxia of Speech: Comparison of EPG Treatment (Tx) and Sound Production Treatment (SPT)CompletedNCT02554513Not applicable1 country
- Evaluating Anodal tDCS Preceding Aphasia TherapyTerminatedNCT02249819Phase 1/21 country
- Transcranial Magnetic Stimulation (TMS) for Primary Progressive Apraxia of Speech (PPAOS)TerminatedNCT03028324Not applicable1 country
- Central Mechanisms in Speech Motor Control Studied With H215O PETTerminatedNCT000013081 country
- Ambulatory Screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).Status unknownNCT04122820Not applicable1 country
- Trial Using CogWatch for Tea Making Training in Stroke Apraxia and Action Disorganisation SyndromeCompletedNCT04044911Not applicable
- Efficacy of an Intervention for the Children With Severe Speech Sounds DisordersStatus unknownNCT03700151Not applicable1 country