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RecruitingNCT06385470Updated Apr 26, 2024

Treatment of Cantonese Speakers With Childhood Apraxia of Speech

An interventional study of Dynamic Temporal and Tactile Cueing treatment in Childhood Apraxia of Speech, sponsored by The Hong Kong Polytechnic University. Recruiting at 1 site in Hong Kong. Open to participants aged 3 Years to 11 Years. Per ClinicalTrials.gov, last updated 2024-04-26.

Sponsored by The Hong Kong Polytechnic University · Not applicable, Interventional, and Treatment

From the registry’s dates

  • Primary completion was expected by Aug 2024, 2 years 3 months ago, but the record still lists the study as recruiting.
  • Started Apr 2024; still recruiting 2 years 6 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
4
Allocation
Not applicable
Ages
3 Years to 11 Years
Sex
All
01

Study summary

The proposed study aims to investigate the efficacy of the Dynamic Temporal and Tactile Cueing treatment in Cantonese-English bilingual speakers with childhood apraxia of speech.

Read the detailed description

Four CE children with CAS will be recruited and receive two versions of the DTTC treatment (i.e., DTTC in English [DTTC-E] and DTTC in Cantonese [DTTC-C]). After the initial assessment and baseline probe sessions, all the participants will be randomly assigned to receive either DTTC-E or DTTC-C in the first 6-week treatment phase. Then, the between-treatment probe sessions will be conducted during a 2-week washout period. This will be followed by the second 6-week treatment phase, which will be the other version of DTTC. Post-treatment probe sessions will be conducted one week and one month after completion of the second treatment.

Participants' speech productions will be transcribed and evaluated based on their accuracy in phonemes, stress, and tone. Growth curve analysis (Mirman, 2014) will be conducted to examine the group differences in the outcome measures across the treatment sessions.

02

Conditions studied

  • Childhood Apraxia of Speech

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03

In context

Apraxias

65 studies on the registry are indexed under Apraxias; 21 are open to participants now.

This study's planned enrollment of 4 is below the median of 32 across 50 interventional studies indexed under Apraxias.

Browse Apraxias studies →

Lead sponsor

The Hong Kong Polytechnic University is the lead sponsor of 679 studies on the registry; 257 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
3 Years to 11 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • (1) 3;0 - 11;11 (years;months) years of age at treatment commencement;
  • (2) speak both Cantonese and English: One caregiver one language for at least one year; speaking different languages at home versus school; and/or speak different languages at different times of day;
  • (3) no concomitant developmental disorders including autism spectrum disorder;
  • (4) no structural abnormalities that affect speech, such as cleft lip and/or palate;
  • (5) no uncorrected vision impairment; and
  • (6) no hearing loss;
  • (7) CAS diagnosis confirmed by the research team based on the available diagnostic criteria in Cantonese speakers, which will be described in the next section

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
4 participants (estimated)

Study arms

  • Experimental
    DTTC treatment

    Four Cantonese-English bilingual children with be randomly assigned to receive either one of the two versions of DTTC (i.e., DTTC in Cantonese \[DTTC-C\] and DTTC in English \[DTTC-E\]) in the first 6-week treatment phase. Then, there will be a 2-week washout period followed by the second 6-week treatment phase with another version of DTTC.

    Behavioral: Dynamic Temporal and Tactile Cueing treatment

Interventions

  • BehavioralDynamic Temporal and Tactile Cueing treatment

    DTTC is a motor-based treatment designed for children with CAS who may have limited verbal output. It applies the principles of motor learning and focuses on speech movement gestures in the context of functional words and phrases. The participants will receive two versions of the DTTC treatment (i.e., DTTC in English \[DTTC-E\] and DTTC in Cantonese \[DTTC-C\]), where probe data will be collected before, during, between and after the treatment intervention.

06

What researchers measure

Primary outcomes

  1. Phonemes accuracy

    Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.

    Time frame: Change Before, Between, 1-week and 5-week post DTTC treatment

  2. Stress accuracy

    Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.

    Time frame: Change Before, Between, 1-week and 5-week post DTTC treatment

  3. Tone accuracy

    Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.

    Time frame: Change Before, Between, 1-week and 5-week post DTTC treatment

07

Study locations

1 of 1 sites recruiting
08

References and documents

Individual participant data

Plan to share: No — The data sets generated and analyzed during this study are not publicly available due to study institutional review board data security requirements.

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 26, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06385470
Responsible party
Dr Min Wong (Assistant Professor, The Hong Kong Polytechnic University) — Principal investigator
First posted
Apr 26, 2024
Start date
Apr 15, 2024
Primary completion
Aug 1, 2024 (estimated)
Completion
Feb 1, 2025 (estimated)
Last update
Apr 26, 2024

Study contacts

Eddy Wong, PhD
Contact
eddy-ch.wong@connect.polyu.hk
(852) 9834 0825
Min Ney Wong, PhD
Contact
min.wong@polyu.edu.hk
(852) 2766 7268
Min Ney Wong, PhD
principal investigator · Study Principal Investigator

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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