Anemia, Sickle Cell: all 1,125 studies

Page 4 of 12. Open to participants first (238), then studies with results posted, then the rest; newest registration first within each.

• Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical StudyTerminatedNCT03733249Phase 1/2Results posted
• A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (V114-023/PNEU-SICKLE)CompletedNCT03731182Phase 3Results posted
• Sickle Cell Anemia WE CARECompletedNCT03716726Not applicableResults posted
• Age of Blood in Sickle Cell TransfusionCompletedNCT03704922Phase 2/3Results posted
• Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell DiseaseTerminatedNCT03694548Not applicableResults posted
• Management of Severe Acute Malnutrition in SCD, in Northern NigeriaCompletedNCT03634488Phase 2Results posted
• Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell DiseaseCompletedNCT03629678Not applicableResults posted
• Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell DiseaseTerminatedNCT03615924Phase 3Results posted
• LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study)CompletedNCT03593395Not applicableResults posted
• Self-Management for Youth and Families Living With SCD - SMYLSCompletedNCT03585543Not applicableResults posted
• Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031TerminatedNCT03573882Phase 3Results posted
• Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises?CompletedNCT03541980Phase 4Results posted
• Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell TransplantationCompletedNCT03513328Phase 1/2Results posted
• Assessing the Safety of Buprenorphine in People With Sickle Cell DiseaseCompletedNCT03492099Phase 2Results posted
• Study of Dose Confirmation and Safety of Crizanlizumab in Pediatric Sickle Cell Disease PatientsCompletedNCT03474965Phase 2Results posted
• Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy TrialCompletedNCT03462511Not applicableResults posted
• Shared-Decision Making for HydroxyureaCompletedNCT03442114Not applicableResults posted
• Ketamine for Acute Painful Crisis in Sickle Cell Disease PatientsCompletedNCT03431285Not applicableResults posted
• A Study of IMR-687 in Adult Participants With Sickle Cell Anemia (Homozygous HbSS or Sickle-β0 Thalassemia)CompletedNCT03401112Phase 2Results posted
• Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD)TerminatedNCT03387033Not applicableResults posted
• Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerTerminatedNCT03333486Phase 2Results posted
• Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive CrisisCompletedNCT03296345Phase 2Results posted
• Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain ManagementCompletedNCT03291613Not applicableResults posted
• A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD)CompletedNCT03285178Phase 2Results posted
• Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC)CompletedNCT03264989Phase 2Results posted
• Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)CompletedNCT03263559Phase 2Results posted
• Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) PatientsCompletedNCT03226691Phase 1Results posted
• iCanCope With Sickle Cell PainCompletedNCT03201874Not applicableResults posted
• Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)CompletedNCT03178643Phase 4Results posted
• Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell DiseaseActive, not recruitingNCT03077542Phase 1/2Results posted
• An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001CompletedNCT03041909Phase 2Results posted
• Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE)CompletedNCT03036813Phase 3Results posted
• Hydroxyurea Management in Kids: Intensive Versus Stable Dosage StrategiesCompletedNCT03020615Phase 2Results posted
• Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell AnemiaCompletedNCT02961218Phase 2Results posted
• Omega-3 Fatty Acids in Sickle Cell DiseaseTerminatedNCT02947100Phase 1/2Results posted
• Topical Sodium Nitrite in Sickle Cell Disease and Leg UlcersTerminatedNCT02863068Phase 2Results posted
• Improving Self-Management in Adolescents With Sickle Cell DiseaseCompletedNCT02851615Not applicableResults posted
• Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell DiseaseTerminatedNCT02850406Phase 2Results posted
• Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)CompletedNCT02766465Phase 2Results posted
• Transplantation for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone MarrowCompletedNCT02757885Phase 2Results posted
• Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent TransfusionsCompletedNCT02731157Phase 4Results posted
• A Phase 1 Study of Continuous Intravenous L-citrulline During Sickle Cell Pain Crisis or Acute Chest SyndromeCompletedNCT02697240Phase 1Results posted
• Macitentan in Pulmonary Hypertension of Sickle Cell DiseaseTerminatedNCT02651272Phase 2Results posted
• A Multi-Center Study of Riociguat in Patients With Sickle Cell DiseasesCompletedNCT02633397Phase 2Results posted
• Arginine Therapy for Sickle Cell Disease PainCompletedNCT02536170Phase 2Results posted
• Carbon Monoxide Measurement to Screen for Sickle Cell DiseaseCompletedNCT02530242Not applicableResults posted
• Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH)CompletedNCT02522104Phase 4Results posted
• European Sickle Cell Disease Cohort - HydroxyureaCompletedNCT02516579Results posted
• Allogeneic SCT of CordIn™, in Patients With HemoglobinopathiesTerminatedNCT02504619Phase 1/2Results posted
• A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell DiseaseCompletedNCT02482298Phase 2Results posted
• Music Therapy in Sickle Cell Transition StudyCompletedNCT02466555Not applicableResults posted
• Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other AnemiasTerminatedNCT02443545Phase 4Results posted
• HSCT For Patients With High Risk Hemoglobinopathies Using Reduced IntensityCompletedNCT02435901Phase 1/2Results posted
• Comparison of Patient Centered Outcomes for People With Sickle Cell Disease in the Acute Care SettingCompletedNCT02411396Results posted
• Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell DiseaseCompletedNCT02410811Results posted
• Preventing Sickle Cell Kidney DiseaseTerminatedNCT02373241Phase 2Results posted
• Evaluation of the AMICUS RBCx System in Sickle Cell PatientsCompletedNCT02372877Not applicableResults posted
• Decision Aid for Therapeutic Options In Sickle Cell DiseaseCompletedNCT02326597Not applicableResults posted
• The Use of Warmed Saline in Vaso-occlusive EpisodesCompletedNCT02316366Not applicableResults posted
• A Dose Escalation Study of Intravenous L-citrulline in Steady-state Sickle Cell DiseaseCompletedNCT02314689Phase 1Results posted
• Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 or 24 Weeks in Genotype 1 or 4 HCV Infected Adults With Sickle Cell DiseaseCompletedNCT02301936Phase 2Results posted
• Families Taking Control (FTC): Family-based Problem-solving Intervention for Children With Sickle Cell DiseaseCompletedNCT02273310Not applicableResults posted
• Music Therapy in Sickle Cell Pain Mixed Methods StudyCompletedNCT02270060Not applicableResults posted
• Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell DiseaseCompletedNCT02225132Phase 1/2Results posted
• Comparing Acute Pain Management Protocols for Patients With Sickle Cell DiseaseCompletedNCT02222246Phase 4Results posted
• A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell DiseaseCompletedNCT02214121Phase 2Results posted
• Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell DiseaseCompletedNCT02200510Not applicableResults posted
• Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell DiseaseCompletedNCT02187003Phase 3Results posted
• Apixaban in Patients With Sickle Cell DiseaseTerminatedNCT02179177Phase 3Results posted
• A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell DiseaseCompletedNCT02151526Phase 1/2Results posted
• A Study Evaluating the Safety and Efficacy of Lovo-cel in Severe Sickle Cell DiseaseCompletedNCT02140554Phase 1/2Results posted
• PATient Navigator to rEduce ReadmissionsCompletedNCT02114515Not applicableResults posted
• Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell DiseaseCompletedNCT02114203Phase 1Results posted
• Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant FailureActive, not recruitingNCT02105766Phase 2Results posted
• Feasibility Study of Unfractionated Heparin in Acute Chest SyndromeTerminatedNCT02098993Phase 2Results posted
• Measurement of Cerebral Blood Flow Using Transcranial Doppler Ultrasound in Children With Sickle Cell DiseaseCompletedNCT02090881Not applicableResults posted
• The Effect of Rivaroxaban in Sickle Cell DiseaseCompletedNCT02072668Phase 2Results posted
• Safety Study of Gene Modified Donor T-cells Following TCRαβ+ Depleted Stem Cell TransplantTerminatedNCT02065869Phase 1/2Results posted
• Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell DiseaseCompletedNCT02061202Phase 2Results posted
• Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other AnemiasTerminatedNCT02041299Phase 4Results posted
• SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCDTerminatedNCT02013375Phase 2Results posted
• Evaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell DiseaseTerminatedNCT01987908Phase 2Results posted
• Novel Use Of Hydroxyurea in an African Region With MalariaCompletedNCT01976416Phase 3Results posted
• Realizing Effectiveness Across Continents With Hydroxyurea (REACH)Active, not recruitingNCT01966731Phase 1/2Results posted
• Phase 2 Study of Montelukast for the Treatment of Sickle Cell AnemiaCompletedNCT01960413Phase 2Results posted
• Pain Management in Children and Young Adults With Sickle Cell DiseaseCompletedNCT01954927Phase 2Results posted
• Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain CrisesCompletedNCT01895361Phase 2Results posted
• Nitrous Oxide Analgesia Vaso-occlusive CrisisCompletedNCT01891812Phase 2Results posted
• Stem Cell Transplantation for Sickle Cell AnemiaCompletedNCT01877837Phase 3Results posted
• Non-Myeloablative Conditioning and Bone Marrow TransplantationActive, not recruitingNCT01850108Not applicableResults posted
• Absorption, Metabolism, and Excretion of a Single Dose of Ferriprox® in Patients With Sickle Cell DiseaseCompletedNCT01835496Phase 1Results posted
• A Study of Prasugrel in Pediatric Participants With Sickle Cell Disease (SCD)TerminatedNCT01794000Phase 3Results posted
• A Phase II Trial of Regadenoson in Sickle Cell AnemiaCompletedNCT01788631Phase 2Results posted
• Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II ProtocolCompletedNCT01783990Results posted
• Vaporized Cannabis for Chronic Pain Associated With Sickle Cell DiseaseCompletedNCT01771731Phase 1/2Results posted
• Evaluation of Spectra Optia Red Blood Cell Exchange in Sickle Cell PatientsCompletedNCT01736657Not applicableResults posted
• Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell DiseaseCompletedNCT01732718Phase 2Results posted
• Effect of Simvastatin Treatment on Vaso-occlusive Pain in Sickle Cell DiseaseCompletedNCT01702246Phase 1/2Results posted
• Allogeneic SCT of NiCord®, UCB-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With HemoglobinopathiesCompletedNCT01590628Phase 1/2Results posted
• Bi-Level Positive Airway Ventilation for Acute Chest SyndromeTerminatedNCT01589926Not applicableResults posted

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