Anemia, Sickle Cell: all 1,125 studies

Page 5 of 12. Open to participants first (238), then studies with results posted, then the rest; newest registration first within each.

• Microvascular Blood Flow in Sickle Cell AnemiaCompletedNCT01566890Not applicableResults posted
• Bone Marrow Transplantation in Young Adults With Severe Sickle Cell DiseaseCompletedNCT01565616Phase 2Results posted
• Effects of Transfusion of Older Stored Red CellsTerminatedNCT01534676Not applicableResults posted
• Sparing Conversion to Abnormal TCD (Transcranial Doppler) Elevation (SCATE)TerminatedNCT01531387Phase 3Results posted
• Intranasal Fentanyl for Initial Treatment of a Vaso-occlusive CrisisCompletedNCT01482091Phase 4Results posted
• Losartan to Reverse Sickle NephropathyCompletedNCT01479439Phase 2Results posted
• A Study of Prasugrel in Pediatric Participants With Sickle Cell DiseaseCompletedNCT01476696Phase 2Results posted
• Vitamin D for Sickle-cell Respiratory ComplicationsCompletedNCT01443728Phase 2Results posted
• A Relative Bioavailability Study of a Prasugrel Orally Disintegrating TabletCompletedNCT01430091Phase 1Results posted
• Transcranial Doppler (TCD) With Transfusions Changing to HydroxyureaTerminatedNCT01425307Phase 3Results posted
• Treatment of Sickle Cell Patients Hospitalized in Pain Crisis With Prophylactic Dose Low-molecular-weight Heparin (LMWH) Versus PlaceboCompletedNCT01419977Phase 2Results posted
• Hydroxyurea to Prevent Brain Injury in Sickle Cell DiseaseCompletedNCT01389024Phase 2Results posted
• Choosing Opioid Management for Pain and Analyzing Acute Chest Syndrome (ACS) Rates EquallyCompletedNCT01380197Phase 3Results posted
• Decitabine for High-Risk Sickle Cell DiseaseCompletedNCT01375608Phase 2Results posted
• Treatment of Sickle Cell Anemia With Stem Cell TransplantTerminatedNCT01350232Not applicableResults posted
• High Dose Vitamin D for Sickle Cell DiseaseCompletedNCT01331148Phase 2Results posted
• Alefacept and Allogeneic Hematopoietic Stem Cell TransplantationTerminatedNCT01319851Not applicableResults posted
• A Reduced Toxicity Allogeneic Unrelated Donor Stem Cell Transplantation (SCT) for Severe Sickle Cell DiseaseTerminatedNCT01279616Phase 2Results posted
• Study of Vitamin D in Children With Sickle Cell DiseaseCompletedNCT01276587Phase 1/2Results posted
• Regional Anesthesia for Sickle Cell Crisis Using Ultrasound in The Emergency Department: Phase ITerminatedNCT01256281Phase 1Results posted
• Intravenous Magnesium for Sickle Cell Vasoocclusive CrisisCompletedNCT01197417Phase 2/3Results posted
• A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemiaCompletedNCT01179217Phase 3Results posted
• An Assessment of Prasugrel on Healthy Adults and Sickle Cell AdultsCompletedNCT01178099Phase 1Results posted
• Immunization of Children Between 8 Weeks and 2 Years of Age With GSK Pneumococcal Vaccine GSK1024850ACompletedNCT01175083Phase 3Results posted
• Prasugrel Versus Placebo in Adult Sickle Cell DiseaseCompletedNCT01167023Phase 2Results posted
• Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO).CompletedNCT01090323Phase 2Results posted
• Adenosine 2A Agonist Lexiscan in Children and Adults With Sickle Cell DiseaseCompletedNCT01085201Phase 1Results posted
• Study of Propranolol as Anti-Adhesive Therapy in Sickle Cell Disease (SCD)CompletedNCT01077921Phase 2Results posted
• Antioxidant Therapy to Reduce Inflammation in Sickle Cell DiseaseCompletedNCT01054768Phase 2Results posted
• Glutamine Therapy for Hemolysis-Associated Pulmonary HypertensionCompletedNCT01048905Phase 2Results posted
• Cardiovascular Complications of Sickle Cell DiseaseCompletedNCT01044901Results posted
• Anticoagulation For Pulmonary Hypertension in Sickle Cell DiseaseTerminatedNCT01036802Phase 2Results posted
• Safety and Efficacy of Sodium Nitrite in Sickle Cell DiseaseTerminatedNCT01033227Phase 1/2Results posted
• Efficacy of Vorinostat to Induce Fetal Hemoglobin in Sickle Cell DiseaseTerminatedNCT01000155Phase 2Results posted
• Clinical Importance of Treating Iron Overload in Sickle Cell DiseaseTerminatedNCT00981370Phase 3Results posted
• Haploidentical PBMC Transplant for Severe Congenital AnemiasActive, not recruitingNCT00977691Phase 1/2Results posted
• Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCsCompletedNCT00957931Phase 2Results posted
• Preventing Acute Chest Syndrome by Transfusion Feasibility StudyCompletedNCT00951808Not applicableResults posted
• Sildenafil for Treatment of Priapism in Men With Sickle Cell AnemiaCompletedNCT00940901Phase 2Results posted
• Study Evaluating 13-valent Pneumococcal Conjugate Vaccine (13vPnC) in Children With Sickle Cell DiseaseCompletedNCT00918580Phase 3Results posted
• Study of Intravenous GMI-1070 in Adults With Sickle Cell DiseaseCompletedNCT00911495Phase 1/2Results posted
• A Rehabilitation Program in Children With Sickle Cell Disease and Cognitive Deficits: a Pilot StudyCompletedNCT00895154Not applicableResults posted
• Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study)CompletedNCT00890396Results posted
• A Safety Study of Eptifibatide in Patients With Sickle Cell DiseaseTerminatedNCT00834899Phase 1/2Results posted
• Methadone in Pediatric and Adult Sickle Cell PatientsCompletedNCT00761085Not applicableResults posted
• Pilot Study for Patients With Poor Response to DeferasiroxCompletedNCT00749515Phase 4Results posted
• Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601)CompletedNCT00745420Phase 2Results posted
• Effectiveness of a Computerized Tool (PAINRelieveIt) to Help Manage Pain Related to Sickle Cell DiseaseCompletedNCT00600665Not applicableResults posted
• Low-Dose Ketamine Infusion for Children With Sickle Cell Disease-Related PainTerminatedNCT00595530Phase 2Results posted
• L-Glutamine Therapy for Sickle Cell AnemiaTerminatedNCT00586209Phase 2Results posted
• Bone Marrow Transplantation, Hemoglobinopathies, SCALLOPTerminatedNCT00578344Not applicableResults posted
• Dexamethasone to Treat Acute Chest Syndrome in People With Sickle Cell DiseaseTerminatedNCT00530270Phase 3Results posted
• Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell DiseaseCompletedNCT00528801Results posted
• Effectiveness of Arginine as a Treatment for Sickle Cell AnemiaCompletedNCT00513617Phase 2Results posted
• Simvastatin (Zocor) Therapy in Sickle Cell DiseaseCompletedNCT00508027Phase 1/2Results posted
• Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell DiseaseTerminatedNCT00492531Phase 2Results posted
• Non-Myeloablative Bone Marrow Transplant for Patients With Sickle Cell Anemia and Other Blood DisordersTerminatedNCT00489281Phase 2Results posted
• A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell DiseaseCompletedNCT00445978Phase 2Results posted
• A Pilot Study of HSCT for Patients With High-risk Hemoglobinopathy Using a Nonmyeloablative Preparative RegimenCompletedNCT00427661Not applicableResults posted
• Hydroxyurea for Children and Young Adults With Sickle Cell Disease and Pulmonary HypertensionTerminatedNCT00350844Phase 1/2Results posted
• Priapism in Boys and Men With Sickle Cell Disease - Demographics, Characteristics and PrevalenceCompletedNCT00300235Results posted
• Steroid Treatment for Sickle Cell Pain CrisisTerminatedNCT00263562Phase 3Results posted
• Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron OverloadCompletedNCT00235391Phase 3Results posted
• Aspirin Prophylaxis in Sickle Cell DiseaseCompletedNCT00178464Phase 1Results posted
• Stem Cell Transplant for HemoglobinopathyCompletedNCT00176852Phase 2/3Results posted
• Allogeneic Stem Cell Transplantation Following Chemotherapy in Patients With HemoglobinopathiesCompletedNCT00153985Phase 2Results posted
• Trial of Oral Glutamine in Patients With Sickle Cell AnemiaTerminatedNCT00131508Phase 2Results posted
• L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 ThalassemiaCompletedNCT00125788Phase 2Results posted
• Stroke With Transfusions Changing to HydroxyureaTerminatedNCT00122980Phase 3Results posted
• Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell DiseaseTerminatedNCT00115336Phase 4Results posted
• Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease PatientsCompletedNCT00110617Phase 2Results posted
• Nitric Oxide Inhalation to Treat Sickle Cell Pain CrisesCompletedNCT00094887Phase 2Results posted
• Silent Cerebral Infarct Transfusion Multi-Center Clinical TrialCompletedNCT00072761Phase 3Results posted
• Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital AnemiasActive, not recruitingNCT00061568Phase 1/2Results posted
• Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell AnemiaCompletedNCT00006400Phase 3Results posted
• Phase II Randomized Trial:Arginine Butyrate Plus Standard Local Therapy in Patients With Refractory Sickle Cell UlcersCompletedNCT00004412Phase 2Results posted
• Allogeneic Mixed Chimerism Stem Cell Transplant Using Campath for Hemoglobinopathies & Bone Marrow Failure SyndromesCompletedNCT00004143Phase 2Results posted
• Evolution of Sickle Cell MaculopathyCompletedNCT07877753
• Objective Neurocognitive Assessment of Young Children With Sickle Cell Disease by Eye-TrackingCompletedNCT07721155
• Expanded Access Protocol for Gene Therapy Utilizing shmiR Lentivirus Vector to Induce Fetal Hemoglobin in Sickle Cell DiseaseTemporarily not availableNCT07640815
• Crizanlizumab Pregnancy Outcomes Intensive MonitoringCompletedNCT07554547
• Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell DiseaseTerminatedNCT07431398Phase 1
• Mindfulness-Based Intervention for Pain and Sleep in Adolescents and Young Adults With Sickle Cell DiseaseCompletedNCT07402811Not applicable
• Prevalence of Abnormal Haemoglobin Variants in Metropolitan Chattogram, BangladeshCompletedNCT07305181
• The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC)CompletedNCT07277023Not applicable
• Prevalence and Hematological Characteristics of HemoglobinopathiesCompletedNCT07180836
• Biotin-Acridine Red Cell Exchange KineticsWithdrawnNCT07155031Phase 2
• Full Assessment of Clinical Transfusion SupportCompletedNCT07094646
• The Radiofrequency Therapy in Management of Sickle Cell Disease Chronic Pain RCT Tested the Effect of TECAR Therapy on Sickle Cell Disease Chronic Pain.CompletedNCT07066072Not applicable
• Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective StudyCompletedNCT07037706
• A Study on the Effect of Etavopivat on Heart Rhythm in Healthy ParticipantsCompletedNCT07023029Phase 1
• Role of Inflammasome in Platelet Activation in Sickle Cell Disease PatientCompletedNCT06986837
• Prophylactic Transfusion In Pregnant in Women With Sickle Cell DiseaseWithdrawnNCT06979492Phase 4
• Effect of Aquatic Exercises on Muscle Strength and Quality of Life in Children With Sickle Cell AnemiaCompletedNCT06939933Not applicable
• A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)Active, not recruitingNCT06924970Phase 2
• Sickle Cell, Pain and Mediterranean DietCompletedNCT06886477Not applicable
• Ultrasound Acute Chest Syndrome Sickle Cell DiseaseCompletedNCT06880679Not applicable
• Opioid Prescribing in the Emergency Department for Sickle Cell DiseaseCompletedNCT06835335
• ERN-EuroBloodNet Registry on Patients with Rare Red Blood Cell Defects and COVID-19CompletedNCT06831799
• Synthetic Generation of Hematological Data Over Federated Computing Frameworks: SCD Use CaseActive, not recruitingNCT06794281

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