Anemia, Sickle Cell: all 1,125 studies
Page 2 of 12. Open to participants first (238), then studies with results posted, then the rest; newest registration first within each.
- Clinical and Biomarker Effects of Depot Medroxyprogesterone Acetate in Females With Sickle Cell DiseaseRecruitingNCT06665997Phase 4
- Decision-Making and Quality of Life Surrounding Hematologic Disease and Gene TherapyEnrolling by invitationNCT06664541
- Adapting the FACETS Program to Sickle Cell DiseaseRecruitingNCT06650813Not applicable
- Hematopoietic Stem Cell BCL11A Enhancer Gene Editing for Severe β-HemoglobinopathiesRecruitingNCT06647979Phase 1
- Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell DiseaseRecruitingNCT06635902Phase 2
- Exploratory Study on Global Reflexology in Sickle Cell DiseaseRecruitingNCT06619197Not applicable
- Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood CoagulationNot yet recruitingNCT06619093
- Screening of Coexistence Between Sickle Cell Anaemia and G6PD DeficiencyNot yet recruitingNCT06615024
- A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell DiseaseRecruitingNCT06612268Phase 3
- A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or ThalassaemiaRecruitingNCT06609226Phase 3
- The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi ArabiaNot yet recruitingNCT06601894
- Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell DiseaseNot yet recruitingNCT06579703Phase 4
- Pharmacokinetics, Efficacy and Safety of Twice Daily Dosing Regimen of Hydroxycarbamide Dispersible Tablets in Children With Sickle Cell DiseaseRecruitingNCT06578507Phase 2
- CS-206 in Patients With Sickle Cell DiseaseRecruitingNCT06565026Early Phase 1
- Development and Evaluation of an Information Management System and Communication System for Population-wide Point-of-care Infant Sickle Cell Disease ScreeningNot yet recruitingNCT06563440Not applicable
- Promoting Resilience Among Adolescents and Young Adults With Sickle Cell DiseaseRecruitingNCT06555939Not applicable
- A Phase I/II Study of ITU512 in Healthy Participants and Patients With Sickle Cell DiseaseRecruitingNCT06546670Phase 1/2
- FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare DiseasesRecruitingNCT06539169
- Pressure Pain Tolerance in Relation to Balance and Strength in ChildrenRecruitingNCT06529874Not applicable
- SCRIPT: Sickle Cell Risk in Pregnancy ToolEnrolling by invitationNCT06529042
- Stroke Prevention in Nigeria 2 TrialRecruitingNCT06526117Phase 4
- Gene Editing For Sickle Cell DiseaseRecruitingNCT06506461Phase 1
- Role of Transcranial Doppler and Magnetic Resonance Angiography for Future Management of Sickle Cell Anemia CNS.Not yet recruitingNCT06498726
- Lung Ultrasound in Pediatric Acute Chest SyndromeRecruitingNCT06497153
- A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell DiseaseRecruitingNCT06481306Phase 1/2
- Peripheral Arterial Tonometry and Neurocognition in Sickle Cell DiseaseRecruitingNCT06477289
- Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological MonitoringRecruitingNCT06464458Not applicable
- SCD Stem Cell Mobilization and Apheresis Using MotixafortideRecruitingNCT06442761Phase 1
- A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE)RecruitingNCT06439082Phase 3
- Physiology and Pathologies Linked to Human Splenic Function : Direct and Ex-vivo Perfusion ExplorationsRecruitingNCT06418256
- Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell DiseaseRecruitingNCT06399107Phase 1/2
- Low Systemic/High Local Exercise Load in Peds SCDRecruitingNCT06387758Not applicable
- Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell DiseaseRecruitingNCT06385886
- Peer Support for Adolescents and Emerging Adults With Sickle Cell PainRecruitingNCT06374238Not applicable
- School Readiness Intervention for Preschool Children With Sickle Cell DiseaseRecruitingNCT06367192Not applicable
- A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301Enrolling by invitationNCT06363760
- Sickle Cell Disease Transplant Using a Nonmyeloablative Approach for Patients With Anti-donor Red Cell AntibodyRecruitingNCT06358638Phase 2
- Comparative Health Status and Quality of Life of Patients With Sickle Cell Disease (SCD) Who Underwent Matched-sibling Hematopoietic Stem Cell Transplantation Versus Non Transplanted SCD Case-control PatientsNot yet recruitingNCT06351462Not applicable
- mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in NigeriaRecruitingNCT06318143Not applicable
- Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency DepartmentNot yet recruitingNCT06315920Phase 3
- Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin LabelingRecruitingNCT06313398Early Phase 1
- Uganda Sickle Surveillance Study (US-3)RecruitingNCT06301893
- Clinical Study of BRL-101 in Severe SCDEnrolling by invitationNCT06300723Not applicable
- A Socio-ecological Approach for Improving Self-management in Adolescents With SCDRecruitingNCT06290401Not applicable
- Clinical Study of BRL-101 in the Treatment of Sickle Cell DiseaseNot yet recruitingNCT06287099Not applicable
- Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell DiseaseNot yet recruitingNCT06287086Not applicable
- Zinc Supplementation in Sickle Cell Disease: A Precursor to the Think Zinc for Bones TrialRecruitingNCT06260891Phase 2
- European Rare Blood Disorders Platform (ENROL)RecruitingNCT06250595
- Early-goal Directed Automated Red Blood Cell Exchange for Acute Chest Syndrome in Sickle Cell DiseaseNot yet recruitingNCT06214845Not applicable
- RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)RecruitingNCT06213402
- A Study to Evaluate the Pharmacokinetics and Safety of Etavopivat in Pediatric Patients With Sickle Cell DiseaseRecruitingNCT06198712Phase 2
- Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive CrisesRecruitingNCT06184126Not applicable
- The Role of Endothelin 1 as a Marker of Renal Impairment in Sickle Cell DiseaseRecruitingNCT06158945
- Development of Non-Invasive Prenatal Diagnosis for Single Gene DisordersRecruitingNCT06147414
- Predictors of Pain in Sickle Cell DiseaseRecruitingNCT06139510Not applicable
- The Living With a Long-Term Condition StudyRecruitingNCT06072287
- SMYLS Multi-site TrialRecruitingNCT06035939Not applicable
- Alendronate for Osteonecrosis in Adults With Sickle Cell DiseaseRecruitingNCT06016634Phase 2
- A Phase 2 Open-label Study to Evaluate the Activity of Etavopivat on Transcranial Doppler Velocities in Pediatric Patients With Sickle Cell Disease Who Are at Increased Risk for Primary StrokeRecruitingNCT05953584Phase 2
- Enablers and Barriers to Hydroxyurea Use for Sickle Cell Disease JamaicaRecruitingNCT05909657
- Do Alemtuzumab Levels Predict T Cell Chimerism After MSD SCT for SCD?RecruitingNCT05905770
- Study to Evaluate the Safety and Tolerability of Escalating Doses of Fostamatinib in Subjects With Stable Sickle Cell DiseaseRecruitingNCT05904093Phase 1
- Pumilio1 (PUM1) Expression, Sickle Cell Anemia, β-thalassemia IntermediaNot yet recruitingNCT05883254
- Genetic and Haematological Modifiers of SCD Severity in Kaduna State, Northern NigeriaNot yet recruitingNCT05837871
- Gene Therapy Communication: Use of a Needs Assessment to Drive Decision-AIDS for Gene Therapy for Rare Diseases (GENETX)RecruitingNCT05810181
- Study of the Role of Genetic Modifiers in HemoglobinopathiesRecruitingNCT05799118
- A Study to Provide Access to Mitapivat for Participants Who Previously Participated in an Agios-Sponsored Mitapivat StudyEnrolling by invitationNCT05777993Phase 4
- ASH Research Collaborative Data HubEnrolling by invitationNCT05775224
- Arterial Function Parameters and Transcranial Doppler Velocity in Paediatric Patients With Sickle Cell DiseaseRecruitingNCT05748717
- A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)RecruitingNCT05736419Phase 2
- Tocilizumab for Acute Chest SyndromeRecruitingNCT05640271Phase 2
- Tissue Repository Providing Annotated Biospecimens for Approved Investigator-directed Biomedical Research InitiativesRecruitingNCT05635266
- Osteopathic Manipulation in the Management of Pain Associated With Sickel Cell DiseaseRecruitingNCT05632289Not applicable
- Minocycline In Neurocognitive Outcomes - Sickle Cell DiseaseNot yet recruitingNCT05605366Phase 1
- Relationship Between Abnormal Myocardial Perfusion and Diastolic Dysfunction in Sickle Cell Disease Using PETRecruitingNCT05583721Phase 2
- Brain Structure and Neurocognitive Development in Sickle Cell Disease; a Longitudinal Cohort Study (BRICK Study)RecruitingNCT05564845
- Nano-rheological Biomarkers for Patients With Sickle Cell Disease (SCD) Versus Control Subjects (Other Constitutional Red Blood Cell Diseases and Healthy Subjects)Not yet recruitingNCT05530239
- Cannabinoids for the Reduction of Inflammation and Sickle Cell Related PainRecruitingNCT05519111Phase 2
- Evaluation of Efficacy and Safety of a Single Dose of CTX001 in Participants With Transfusion-Dependent β-Thalassemia and Severe Sickle Cell DiseaseRecruitingNCT05477563Phase 3
- Crizanlizumab Improves Tissue Oxygen Supply Demand Matching in Patients With Sickle Cell AnemiaNot yet recruitingNCT05469828Phase 1/2
- Primary Prevention of Stroke in Children With Sickle Cell Anaemia in Nigeria in the CommunityRecruitingNCT05434000Not applicable
- A Phase 2/3 Study of Osivelotor in Adult and Adolescent Participants With SCDRecruitingNCT05431088Phase 2/3
- RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell DiseaseRecruitingNCT05392894Phase 3
- Empowering Adolescents and Young Adults With Sickle Cell Disease as Partners in Treatment Decision Making (EMPOWER-AYA)RecruitingNCT05383911Not applicable
- Early Life Exposures Among Children With Sickle Cell DiseaseRecruitingNCT05377372Not applicable
- Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease (SCD-TGA)RecruitingNCT05376046
- Exercise in Child HealthRecruitingNCT05359991Not applicable
- Cognitive Remediation Intervention to Prepare for Transition of CareRecruitingNCT05336201Phase 2
- Study of Crizanlizumab for Prevention of Silent Cerebral Infarcts in SCARecruitingNCT05334576Not applicable
- Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD)RecruitingNCT05289700Phase 3
- Promoting Utilization and Safety of Hydroxyurea Using Precision in AfricaRecruitingNCT05285917Phase 3
- The Predictive Capacity of Machine Learning Models for Progressive Kidney Disease in Individuals With Sickle Cell AnemiaRecruitingNCT05214105
- Cutaneous Hydration Assessment in SCDRecruitingNCT05210114Not applicable
- Preservation and Transfer of HBV Immunity After Allogeneic HSCT for SCDRecruitingNCT05200338Not applicable
- Hemolysis Related Complications in SCD. A Phase II Study With VoxelotorRecruitingNCT05199766Phase 2
- Dietary Intake and Dietary Behaviors in Adults With Sickle Cell DiseaseRecruitingNCT05170412
- Feasibility and Efficacy of Attentional-Control Training in Sickle Cell DiseaseRecruitingNCT05099874Not applicable
- Gene Correction in Autologous CD34+ Hematopoietic Stem Cells (HbS to HbA) to Treat Severe Sickle Cell DiseaseRecruitingNCT04819841Phase 1/2
- Transplantation of Clustered Regularly Interspaced Short Palindromic Repeats Modified Hematopoietic Progenitor Stem Cells (CRISPR_SCD001) in Patients With Severe Sickle Cell DiseaseRecruitingNCT04774536Phase 1/2
- Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab StudyRecruitingNCT04657822Phase 4