Amyotrophic Lateral Sclerosis: all 1,000 studies

Page 4 of 10. Open to participants first (284), then studies with results posted, then the rest; newest registration first within each.

• A Study to Evaluate, Safety, Tolerability, and PK of AP-101 in Participants With ALSCompletedNCT05039099Phase 2Results posted
• Effectiveness of Expiratory Muscle Strength Training for Improving Communication in ALSCompletedNCT05003167Not applicableResults posted
• TJ-68 Clinical Trial in Patients With Amyotrophic Lateral Sclerosis (ALS) and Muscle CrampsCompletedNCT04998305Phase 1/2Results posted
• ALS and Airway Clearance (ALSAC) TherapyCompletedNCT04947436Not applicableResults posted
• A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT04944784Phase 3Results posted
• Remotely Supervised tDCS for Slowing ALS Disease ProgressionCompletedNCT04866771Not applicableResults posted
• Geometrical Facial Deformation According to Posture in Amyotrophic Lateral SclerosisCompletedNCT04798183Results posted
• Safety of Engensis in Participants With Amyotrophic Lateral SclerosisCompletedNCT04632225Phase 2Results posted
• HEALEY ALS Platform Trial - Regimen D PridopidineCompletedNCT04615923Phase 2/3Results posted
• MERIDIAN: A Study to Evaluate the Efficacy and Safety of Pegcetacoplan in Adults With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT04579666Phase 2Results posted
• Safety Extension Study of Oral Edaravone Administered in Subjects With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT04577404Phase 3Results posted
• Trial of Theracurmin for Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT04499963Phase 2Results posted
• A Study to Assess the Safety, Tolerability, and Effect on Disease Progression of BIIB105 in Participants With Amyotrophic Lateral Sclerosis (ALS) and Participants With the ALS Ataxin-2 (ATXN2) Genetic MutationTerminatedNCT04494256Phase 1/2Results posted
• HEALEY ALS Platform Trial - Regimen B VerdiperstatCompletedNCT04436510Phase 2/3Results posted
• HEALEY ALS Platform Trial - Regimen A ZilucoplanCompletedNCT04436497Phase 2/3Results posted
• HEALEY ALS Platform Trial - Regimen C CNM-Au8CompletedNCT04414345Phase 2/3Results posted
• Multiple Doses of AT-1501-A201 in Adults With ALSCompletedNCT04322149Phase 2Results posted
• An Efficacy and Safety Study of Ravulizumab in ALS ParticipantsTerminatedNCT04248465Phase 3Results posted
• Clenbuterol on Motor Function in Individuals With Amyotrophic Lateral SclerosisCompletedNCT04245709Phase 2Results posted
• Safety and Therapeutic Potential of the FDA-approved Drug Metformin for C9orf72 ALS/FTDActive, not recruitingNCT04220021Phase 2Results posted
• Therapeutic Nanocatalysis to Slow Disease Progression of Amyotrophic Lateral Sclerosis (ALS)CompletedNCT04098406Phase 2Results posted
• Study of Safety and Proof of the Mechanism of BLZ945 in ALS PatientsTerminatedNCT04066244Phase 2Results posted
• Transmembrane Electromyography (TM-EMG) for the Assessment of Neuromuscular Function in the OropharynxCompletedNCT03986671Not applicableResults posted
• Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label ExtensionTerminatedNCT03948178Phase 3Results posted
• Impact of Nuedexta on Bulbar Physiology and Function in ALSCompletedNCT03883581Phase 1/2Results posted
• Effects of Remote Ischemic Conditioning on Hand Use in Individuals With SCI and ALSCompletedNCT03851302Not applicableResults posted
• Arimoclomol in Amyotropic Lateral Sclerosis - Open Label Extension TrialTerminatedNCT03836716Phase 3Results posted
• A Safety and Tolerability Study of ILB® in Patients With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT03705390Phase 2Results posted
• Riluzole Oral Soluble Film (ROSF) Swallowing Safety in Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT03679975Phase 2Results posted
• Acute Intermittent Hypoxia and Breathing in Neuromuscular DiseaseCompletedNCT03645031Not applicableResults posted
• Tolerability and Efficacy of L-Serine in Patients With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT03580616Phase 2Results posted
• A Pilot Trial of Triheptanoin for People With Amyotrophic Lateral Sclerosis (PALS)CompletedNCT03506425Phase 1/2Results posted
• Effects of Oral Levosimendan (ODM-109) on Respiratory Function in Patients With ALSCompletedNCT03505021Phase 3Results posted
• Arimoclomol in Amyotropic Lateral SclerosisCompletedNCT03491462Phase 3Results posted
• Open Label Extension Study of AMX0035 in Patients With ALSCompletedNCT03488524Phase 2Results posted
• Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral SclerosisCompletedNCT03472950Phase 2Results posted
• The Effect of RNS60 on ALS BiomarkersCompletedNCT03456882Phase 2Results posted
• Cervical Electrical Stimulation for ALSCompletedNCT03411863Not applicableResults posted
• Rehabilitative Trial With tDCS in Amyotrophic Lateral SclerosisCompletedNCT03293394Not applicableResults posted
• Safety and Efficacy of Repeated Administrations of NurOwn® in ALS PatientsCompletedNCT03280056Phase 3Results posted
• Intrathecal Autologous Adipose-derived Mesenchymal Stromal Cells for Amyotrophic Lateral Sclerosis (ALS)Active, not recruitingNCT03268603Phase 2Results posted
• Ph1 T-Regulatory Cells in Amyotrophic Lateral SclerosisCompletedNCT03241784Phase 1Results posted
• Remote Pulmonary Function Testing in Amyotrophic Lateral Sclerosis (Pilot)CompletedNCT03214224Not applicableResults posted
• Physiological Flow of Liquids Used in Dysphagia Management (Neuro)CompletedNCT03192358Results posted
• Safety of Urate Elevation in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT03168711Phase 2Results posted
• A Study to Evaluate Efficacy, Safety and Tolerability of CK-2127107 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT03160898Phase 2Results posted
• AMX0035 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT03127514Phase 2Results posted
• Study of Acthar® Gel (Acthar) for Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT03068754Phase 2/3Results posted
• A Study for Patients Who Completed VITALITY-ALS (CY 4031)CompletedNCT02936635Phase 3Results posted
• Safety and Feasibility of the EyeControl DeviceCompletedNCT02891629Not applicableResults posted
• Efficacy and Safety of Plasma Exchange With Albutein® 5% in Participants With Amyotrophic Lateral SclerosisCompletedNCT02872142Phase 2Results posted
• Mexiletine in Sporadic Amyotrophic Lateral SclerosisCompletedNCT02781454Phase 2Results posted
• A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Literal Sclerosis (ALS)CompletedNCT02714036Phase 1/2Results posted
• ALS Reversals - Lunasin RegimenCompletedNCT02709330Phase 2Results posted
• The Use of Airway Clearance Devices in ALSCompletedNCT02682030Not applicableResults posted
• DESIPHER_Speech Degradation as an Indicator of Physiological Degeneration in ALSCompletedNCT02675075Results posted
• An Efficacy, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Study of BIIB067 (Tofersen) in Adults With Inherited Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02623699Phase 3Results posted
• Ventilatory Investigation of Tirasemtiv and Assessment of Longitudinal Indices After Treatment for a YearCompletedNCT02496767Phase 3Results posted
• Efficacy and Safety of Plasma Exchange With Albumin in Patients With Amyotrophic Lateral SclerosisCompletedNCT02479802Phase 2Results posted
• A Trial of Tocilizumab in ALS SubjectsCompletedNCT02469896Phase 2Results posted
• Safety and Biomarker Study of EPI-589 in Participants With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02460679Phase 2Results posted
• Clinical Trial of Ezogabine (Retigabine) in ALS SubjectsCompletedNCT02450552Phase 2Results posted
• Exploratory Study of Biotelemetry in Amyotrophic Lateral SclerosisCompletedNCT02447952Not applicableResults posted
• HERV-K Suppression Using Antiretroviral Therapy in Volunteers With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02437110Phase 1Results posted
• Electronic-health Application To Measure Outcomes REmotely Clinical TrialCompletedNCT02418546Not applicableResults posted
• A Pilot Study of Inosine in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02288091Phase 1Results posted
• Ibudilast (MN-166) in Subjects With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT02238626Phase 2Results posted
• Therapy in Amyotrophic Lateral Sclerosis (TAME)CompletedNCT02118727Phase 2Results posted
• Safety Study of VM202 to Treat Amyotrophic Lateral SclerosisCompletedNCT02039401Phase 1/2Results posted
• Phase 2, Randomized, Double Blind, Placebo Controlled Multicenter Study of Autologous MSC-NTF Cells in Patients With ALSCompletedNCT02017912Phase 2Results posted
• Efficacy and Safety Study of MYOBLOC® in the Treatment of Sialorrhea in Adult SubjectsCompletedNCT01994109Phase 3Results posted
• Amyotrophic Lateral Sclerosis Registry Rhineland-PalatinateCompletedNCT01955369Results posted
• A Study to Explore the Safety and Tolerability of Acthar in Patients With Amyotrophic Lateral SclerosisCompletedNCT01906658Phase 2Results posted
• Immunosuppression in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01884571Phase 2Results posted
• Mexiletine in Sporadic Amyotrophic Lateral Sclerosis (SALS)CompletedNCT01849770Phase 2Results posted
• Mexiletine for the Treatment of Muscle Cramps in ALSCompletedNCT01811355Phase 4Results posted
• Clinical Trial Nuedexta in Subjects With ALSCompletedNCT01806857Phase 2Results posted
• Rasagiline in Subjects With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01786603Phase 2Results posted
• Gilenya in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01786174Phase 2Results posted
• Study of Ozanezumab (GSK1223249) Versus Placebo in the Treatment of Amyotrophic Lateral SclerosisCompletedNCT01753076Phase 2Results posted
• Study of Safety, Tolerability & Efficacy of CK-2017357 in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01709149Phase 2Results posted
• Phase 3 Extension Study of Dexpramipexole in ALSTerminatedNCT01622088Phase 3Results posted
• Phase 3 Study of MCI-186 for Treatment of Amyotrophic Lateral SclerosisCompletedNCT01492686Phase 3Results posted
• Safety and Efficacy Study of Autologous Bone Marrow Derived Stem Cell Treatment in Amyotrophic Lateral SclerosisCompletedNCT01363401Phase 1/2Results posted
• Phase 3 Study of Dexpramipexole in ALSCompletedNCT01281189Phase 3Results posted
• Safety and Efficacy Study of Creatine and Tamoxifen in Volunteers With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01257581Phase 2Results posted
• Trial of Safety and Efficacy of Rasagiline in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01232738Phase 2Results posted
• Study of Standard Noninvasive Positive Pressure Ventilation (NIPPV) and Low Expiratory Pressure NIPPV in ALS PatientsCompletedNCT01154283Not applicableResults posted
• An In-home Study of Brain Computer InterfacesCompletedNCT01123200Not applicableResults posted
• A P300 Brain Computer Interface to Operate Power Wheelchair TiltCompletedNCT01123148Not applicableResults posted
• A P300 Brain Computer Interface Keyboard to Control Assistive Technology For Use by People With Amyotrophic Lateral SclerosisCompletedNCT01119001Not applicableResults posted
• SOD1 Inhibition by Pyrimethamine in Familial Amyotrophic Lateral Sclerosis (ALS)CompletedNCT01083667Phase 1/2Results posted
• High Fat/High Calorie Trial in Amyotrophic Lateral SclerosisCompletedNCT00983983Phase 2Results posted
• Escitalopram (Lexapro) for Depression MS or ALSCompletedNCT00965497Phase 3Results posted
• Open-Label, Safety and Tolerability Extension Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS) (CL211)CompletedNCT00931944Phase 2Results posted
• Efficacy and Tolerability of Tauroursodeoxycholic Acid in Amyotrophic Lateral SclerosisCompletedNCT00877604Phase 2Results posted
• Safety and Efficacy of TRO19622 as add-on Therapy to Riluzole Versus Placebo in Treatment of Patients Suffering From ALSCompletedNCT00868166Phase 3Results posted
• P300 Brain Computer Interface Keyboard to Operate Assistive TechnologyCompletedNCT00860951Phase 1/2Results posted
• Study to Investigate the Safety and Efficacy of Lithium in Volunteers With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT00818389Phase 2/3Results posted
• A Multi-Center Controlled Screening Trial of Safety and Efficacy of Lithium Carbonate in Subjects With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT00790582Phase 2Results posted

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