Amyotrophic Lateral Sclerosis: all 1,000 studies

Page 5 of 10. Open to participants first (284), then studies with results posted, then the rest; newest registration first within each.

• A Clinical Demonstration of EEG Brain-computer Interface for ALS PatientsCompletedNCT00786032Results posted
• Safety and Tolerability Study of KNS-760704 in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT00647296Phase 2Results posted
• Electrical Impedance Myography as an Outcome Measure in Amyotrophic Lateral Sclerosis Clinical TrialsCompletedNCT00620698Results posted
• Safety and Efficacy of AVP-923 in PBA Patients With ALS or MSCompletedNCT00573443Phase 3Results posted
• Effect of Noninvasive Ventilation on Lung Function in Amyotrophic Lateral SclerosisTerminatedNCT00537446Not applicableResults posted
• Expanded Controlled Study of Safety and Efficacy of MCI-186 in Patients With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT00424463Phase 3Results posted
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS) Who Met Severity Classification IIICompletedNCT00415519Phase 3Results posted
• Clinical Trial Ceftriaxone in Subjects With ALSCompletedNCT00349622Phase 3Results posted
• Efficacy and Safety Study of MCI-186 for Treatment of Amyotrophic Lateral Sclerosis (ALS)CompletedNCT00330681Phase 3Results posted
• Clinical Trial of Glatiramer Acetate in Amyotrophic Lateral Sclerosis (ALS)CompletedNCT00326625Phase 2Results posted
• Clinical Trial of High Dose CoQ10 in ALSCompletedNCT00243932Phase 2Results posted
• Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure VentilationCompletedNCT00116558Not applicableResults posted
• Safety Study of Botulinum Toxin Type A in Post-Upper Limb Stroke Patients With Reduced Lung FunctionCompletedNCT00076687Phase 2Results posted
• Insulin-like Growth Factor-1 in Amyotrophic Lateral Sclerosis (ALS) TrialCompletedNCT00035815Phase 3Results posted
• The Aim of the Study is to Characterize Patients Exhibiting Muscular Atrophy and Weakness Who Require a Muscle Biopsy for Diagnosis (IBM vs Atypical MND), Through an Innovative Technique Which Enables the Evaluation of the Neuromuscular Junction Involvement in Each ConditionActive, not recruitingNCT07796776
• Study of Home Use of the Jaco Robotic Manipulation Device by Individuals With TetraplegiaCompletedNCT07680361Not applicable
• HFCWO Vest Plus Mechanical Cough Assist Versus Cough Assist Alone on Respiratory Infections in ALS: a Pilot TrialCompletedNCT07656714Not applicable
• The Meals Study for Amyotrophic Lateral Sclerosis and Parkinson's DiseaseCompletedNCT07625605Not applicable
• Safety and Efficacy of Intrathecal NTF001 Injection in ALSActive, not recruitingNCT07618585Phase 1
• HEALEY ALS Platform Trial - Regimen I NUZ-001Active, not recruitingNCT07410806Phase 2/3
• Comprehensive Biomarker Profiling of the IFN-α Pathway in Amyotrophic Lateral Sclerosis Patient BiofluidsCompletedNCT07260981
• A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Chinese Participants With SOD-1 Amyotrophic Lateral Sclerosis (ALS)Active, not recruitingNCT07223723Phase 4
• Intravenous Immunoglobulin (IVIG) and Blood-Brain Barrier Disruption in Amyotrophic Lateral Sclerosis (ALS)Active, not recruitingNCT07193953Phase 1
• Longitudinal Evaluation of Short-Chain Fatty Acid Profiles During the Natural Disease Course and a Mediterranean Diet Intervention in Amyotrophic Lateral Sclerosis PatientsCompletedNCT07178067
• Study of COYA 302 for the Treatment of ALSActive, not recruitingNCT07161999Phase 2/3
• Obi Medical Robot: Evaluating Effectiveness Related to UsabilityActive, not recruitingNCT07151950
• Amyotrophic Lateral Sclerosis: A Multicenter Retrospective Observational RegistryActive, not recruitingNCT07143656
• Personalized Antisense Oligonucleotide Therapy for A Single Participant With TARDBP ALSCompletedNCT07095712Phase 1/2
• Trial of Oral Digoxin in Individuals With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT07047209Phase 2
• Personalized Antisense Oligonucleotide for a Single Participant With CHCHD10 ALSActive, not recruitingNCT06977451Phase 1/2
• A Study of STRO4 in Patients Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT06910384Phase 2
• Extension Study of Participants From SPG302-ALS-001TerminatedNCT06903286Phase 2
• Safety and Efficacy of Intravenous Administration of SHED-CM for ALSActive, not recruitingNCT06889857Early Phase 1
• Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical ApproachesActive, not recruitingNCT06856850
• Effects of L-Carnitine in Amyotrophic Lateral Sclerosis Patients With CHCHD10 MutationsCompletedNCT06849115Phase 4
• Transcranial Static Magnetic Stimulation (tSMS) and Potential Theranostic Biomarkers in Amyotrophic Lateral Sclerosis.Active, not recruitingNCT06834269Not applicable
• A First in Human Study of ORT247 in Healthy VolunteersCompletedNCT06769620Phase 1
• A Study Exploring the PK/PD Relationship of QRL-101 in Adults With ALSCompletedNCT06714396Phase 1
• Evaluate the Safety of Neuronata-R® Inj. Suspended With HypoTHermosol® FRS (HTS-FRS) in Patients With ALSCompletedNCT06676423Phase 1
• RolloverTreatment With Triumeq for People With ALS Following the Lighthouse II TrialTerminatedNCT06658977Phase 3
• A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)Active, not recruitingNCT06643481Phase 2
• Retrospective Study on the Safety and Therapeutic/Improvement Effects of Intravenous Administration of SHED-CM for ALS (SHED-CAH2023)CompletedNCT06608719
• Human Amniotic Mesenchymal Cell Secretome for Neurodegeneration and NeuroinflammationActive, not recruitingNCT06551649Not applicable
• Evaluate the Safety and Efficacy of Intrathecal Injection of RJK002 in Patients With Amyotrophic Lateral SclerosisActive, not recruitingNCT06493279Phase 1
• An IIT Clinical Study to Evaluate the Safety and Efficacy of a Single Intrathecal Injection of RJK002 in Patients With ALSActive, not recruitingNCT06454682Early Phase 1
• A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) PatientsTerminatedNCT06453668Phase 1
• A Safety and Efficacy Study of ARGX-119 in Adult Patients With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT06441682Phase 2
• ROAR-DIGAP: A Widely Inclusive, Largely Virtual Pilot Trial Utilizing DIGAP (Deep Integrated Genomics Analysis Platform) To Personalize TreatmentsCompletedNCT06429059Phase 2
• Intermediate Expanded Access Protocol CNMAu8.EAP04Temporarily not availableNCT06408727
• Personalized Antisense Oligonucleotide Therapy for A Single Participant With CHCHD10 ALSActive, not recruitingNCT06392126Phase 1/2
• ALS Phase II Study of NX210cActive, not recruitingNCT06365216Phase 2
• The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular DisorderCompletedNCT06363357Not applicable
• Perception of Unpleasant Sensations During Study Procedures in ALS PatientsCompletedNCT06325865
• Digital Assessment of Speech and Fine Motor Control in ALSCompletedNCT06315673
• Study in ALS With Abatacept & IL-2CompletedNCT06307301Phase 1
• A Study of VRG50635 in Healthy VolunteersCompletedNCT06286475Phase 1
• Ultra-high-caloric, Fatty Diet in ALSActive, not recruitingNCT06280079Not applicable
• Virtual Reality in Motor Neurone DiseaseCompletedNCT06256107Not applicable
• A Study of VRG50635 in Participants With Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT06215755Phase 1
• Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register StudyActive, not recruitingNCT06209515
• Contralateral R1 in Amyotrophic Lateral SclerosisCompletedNCT06206629
• Atalante Exoskeleton in the Rehabilitation of Patients With Amyotrophic Lateral SclerosisSuspendedNCT06199284Not applicable
• An Open Label Extension Study of Monepantel in Individuals With Motor Neurone DiseaseCompletedNCT06177431Phase 1
• RAPA-501 Therapy of ALS Expanded Access ProtocolTemporarily not availableNCT06169176
• Early Feasibility Study of the MyoRegulator® for Treatment of ALSCompletedNCT06165172Not applicable
• Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) StudyCompletedNCT06119087Not applicable
• Continuation Study for LatozinemabTerminatedNCT06111014Phase 3
• Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants With SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)Active, not recruitingNCT06100276Phase 1/2
• A Second Intermediate-Size Expanded Access Protocol (EAP) for Pridopidine in People With Amyotrophic Lateral Sclerosis (Pridopidine EAP 2)No longer availableNCT06069934
• Platform Trial to Assess the Efficacy of Multiple Drugs in Amyotrophic Lateral Sclerosis (ALS)TerminatedNCT06008249Phase 3
• Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral SclerosisCompletedNCT05981040Phase 2
• Yogic Breathing Exercise for People With Amyotrophic Lateral SclerosisCompletedNCT05979688Not applicable
• Safety and Dosimetry of a New Radiotracer to Detect Misfolded SOD1 Associated With Amyotrophic Lateral SclerosisCompletedNCT05974579Phase 1
• Study of AROSOD-1 in Adult Participants With Amyotrophic Lateral Sclerosis (ALS)WithdrawnNCT05949294Phase 1
• Exploring Accessible Beauty for Individuals With Upper Extremity DeficitsCompletedNCT05945784
• ALS Diagnosis From a Saliva Sample: a Non-coding RNA Analysis ApproachActive, not recruitingNCT05928416
• Safety and Tolerance of RAG-17 in Amyotrophic Lateral Sclerosis Patients With SOD1 Gene MutationCompletedNCT05903690Early Phase 1
• Safety and Gut Microbiota Analysis of an Oral Microbiotherapy in Patients With Amyotrophic Lateral SclerosisCompletedNCT05889572Phase 1
• Study of SPG302 in Healthy Volunteers and ALS ParticipantsCompletedNCT05882695Phase 1
• Registry Study of Assistive Devices, Medicines and Healthcare Measures in ALS, SMA and Other Neurological Diseases.CompletedNCT05852418
• Clinical Characteristics, Natural History, Health Care Measures, and Genetic Screening in Patients With ALSCompletedNCT05852405
• Amyotrophic Lateral Sclerosis Non-invasive Ventilation ExchangeTerminatedNCT05837507Not applicable
• Digital Smartwatch Measurements as Potential Biomarkers for Remote Disease Tracking in ALSWithdrawnNCT05830214
• Ambulatory Versus Inpatient Initiation of Home Mechanical VentilationCompletedNCT05829330Not applicable
• A Study to Assess the Effect of Erythromycin on the Test Medicine (SAR443820) When Given Orally as Tablets to Healthy Adult Male and Female Participants (Part A); and the Effect of Itraconazole on the Test Medicine (SAR443820) When Given Orally as Capsules to Healthy Adult Male Participants (Part B)CompletedNCT05797753Phase 1
• A Study in Healthy Adult Male & Female Participants to Assess the Amount of the Study Medicine (SAR443820) Absorbed by the Body, When Given Orally in Fasted Condition as a Tablet Versus as a Capsule (Part 1) and When Given Orally as a Tablet in Fasted Condition Versus as a Tablet After Food (Part 2)CompletedNCT05797701Phase 1
• Single & Multiple Ascending Dose Study of SAR443820 in Healthy Adult ParticipantsCompletedNCT05795907Phase 1
• Counterfactual Thinking in Amyotrophic Lateral SclerosisStatus unknownNCT05768646
• Open Label Extension of TUDCA-ALS StudyStatus unknownNCT05753852Phase 3
• Virtual Seating Coach on Power Wheelchairs of Persons With Amyotrophic Lateral Sclerosis (ALS)CompletedNCT05742828Not applicable
• The Effect of Low-İntensity Combined Exercises in Patients With Early Stage ALS.Status unknownNCT05716074Not applicable
• Regulatory T Cells for Amyotrophic Lateral SclerosisActive, not recruitingNCT05695521Phase 1
• A Study Evaluating the Safety and Tolerability of QRL-201 in ALSActive, not recruitingNCT05633459Phase 1
• Satisfaction of Patients With Amyotrophic Lateral Sclerosis Regarding Home Assisted TeleconsultationTerminatedNCT05621213Not applicable
• Extension Study Evaluating The Safety And Tolerability of AMX0035CompletedNCT05619783Phase 3
• Intermediate-Sized Expanded Access StudyNo longer availableNCT05597436
• A Mindful Community for People With ALS and Their Primary CaregiversCompletedNCT05595850Not applicable
• Factors Associated With Success of NIPPV in ALS PatientsCompletedNCT05581771
• Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIPCompletedNCT05562960Not applicable
• Quality of Life Evaluation with the SRI Questionnaire of ALS Patient with Non-invasive VentilationCompletedNCT05498883Not applicable

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