Amyotrophic Lateral Sclerosis: all 1,000 studies
Page 1 of 10. Open to participants first (284), then studies with results posted, then the rest; newest registration first within each.
- A Study of LY3873862 in Participants With Sporadic or Familial Amyotrophic Lateral Sclerosis (ALS).Not yet recruitingNCT07883590Phase 1
- Safety, Tolerability, and Pharmacodynamic Exploration of Orelabrutinib in Patients With Amyotrophic Lateral Sclerosis (ALS)Not yet recruitingNCT07875972Phase 1
- Brain-Computer Interface Communication Device for People With ALSRecruitingNCT07871071Not applicable
- PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in AdultsNot yet recruitingNCT07865260Not applicable
- Early Access Program for Ulefnersen in Children, Adolescents and Adults With FUS-associated Amyotrophic Lateral Sclerosis (FUS-ALS)AvailableNCT07862959
- A Study to Learn About the Safety of BIIB147 and Its Effects in Adults With Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07855211Phase 1/2
- Metabolism and Nutrition in MNDNot yet recruitingNCT07851714
- Developing New Ways to Detect Respiratory Impairment Early in ALSRecruitingNCT07844590
- Evaluation of Donor-Derived B Cell Infusions in Patients With Amyotrophic Lateral Sclerosis (ALS)Not yet recruitingNCT07838389Phase 1
- Using Gaze to Enable Head-neck Movements in Patients With Head DropRecruitingNCT07836751Not applicable
- Efficacy and Safety of Cyclophosphamide in Amyotrophic Lateral SclerosisNot yet recruitingNCT07834450Phase 2
- A Phase II Study of ALT001 in Patients With Amyotrophic Lateral Sclerosis (ALS)Not yet recruitingNCT07833618Phase 2
- Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body MyositisRecruitingNCT07823101
- Development in Home Mechanical Ventilation for Patient With Amyotrophic Lateral Sclerosis.Not yet recruitingNCT07819890
- 7T Imaging Pilot-study in Patients With Motor Neuron Disease to Find Non-Invasive Disease Imaging BiomarkersRecruitingNCT07818772
- Colchicine Effect on Amyotrophic Lateral Sclerosis PatientsNot yet recruitingNCT07813858Phase 2
- Biofluid Research on Age-Related or Inherited NeurodegenerationRecruitingNCT07798700
- Personalized Antisense Oligonucleotide Therapy for Participants With TARDBP ALSEnrolling by invitationNCT07743268Phase 1/2
- Developing a Comprehensive Biomarker Panel for Monitoring Progression and Early Detection in ALS PatientsNot yet recruitingNCT07737977
- Plasmapheresis in Amyotrophic Lateral Sclerosis With Autoantibody Against NRIP 2 (PALADIN2)RecruitingNCT07726563Not applicable
- Serum Neurofilaments in the Diagnosis of Amyotrophic Lateral SclerosisNot yet recruitingNCT07706270
- Personalized Antisense Oligonucleotide Therapy for a Participant With TARDBP ALSEnrolling by invitationNCT07703462Phase 1/2
- Evaluation of the Feasibility and Efficacy of a Chronic Brain-computer Interface for Speech Rehabilitation in Patients With Locked-in-syndrome (LIS)Not yet recruitingNCT07698496Not applicable
- The BANYAN Trial, an ALS MyMatch Trial Evaluating Safety, Biomarker Activity, and Microglial Activation of Nasal ForalumabNot yet recruitingNCT07688239Phase 2
- FUNCtion ALS: Aiming to Restore UNC13A Function in People Living With ALSRecruitingNCT07674667Phase 1/2
- A Study of LTX-002 in Adult Participants With Amyotrophic Lateral SclerosisRecruitingNCT07660614Phase 1/2
- Auto-calibrating System for Upper Limb Disability Assessment, Neurological and Occupational RehabilitationNot yet recruitingNCT07636538Not applicable
- Evaluation of the Impact of Virtual Park on Training Motivation in Adult PatientsNot yet recruitingNCT07616050Not applicable
- Transcutaneous Superior Laryngeal Nerve Stimulation to Upregulate Swallowing Frequency and Urge to Swallow in Patients Living With ALSNot yet recruitingNCT07606235Not applicable
- Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.Enrolling by invitationNCT07595666Not applicable
- Pilot Trial Utilizing β-hydroxy-β-methylbutyrate to Lower IGFBP7 Levels in People With ALSNot yet recruitingNCT07589764Phase 1
- Alter-Ego as an Assistive Robotic Device.Not yet recruitingNCT07572838
- Therapeutic Approach of Repeated Transient Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis.RecruitingNCT07571486Phase 1/2
- A Master Protocol (OLMP): A Study of LY4256984 in Participants With Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07571200Phase 1
- A Substudy of LY4256984 in Participants With Sporadic Amyotrophic Lateral SclerosisRecruitingNCT07571174Phase 1
- Tracking and Predicting How Brain Damage Spreads in Neurodegenerative DiseasesEnrolling by invitationNCT07567664Not applicable
- INdependence Through Endovascular Neuroprosthetic Technology (INTENT): an Early Feasibility StudyRecruitingNCT07543367Not applicable
- Unrelated Umbilical Cord Blood Transplantation for the Treatment of Amyotrophic Lateral Sclerosis (ALS)Enrolling by invitationNCT07539662Not applicable
- Functional Outcomes and Control Using Synchron BCI - AustraliaRecruitingNCT07533903Not applicable
- Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT)RecruitingNCT07521930Not applicable
- Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic DisordersRecruitingNCT07509125Not applicable
- Diagnostic Accuracy of SleepImage Technology for Detecting Respiratory Failure in Patients With Amyotrophic Lateral SclerosisRecruitingNCT07502677
- Evaluation of a Structurally Suitable Neck Exoskeleton in Patients With Amyotrophic Lateral SclerosisRecruitingNCT07491562Not applicable
- Impact of Physical Functioning on Patient-Reported Outcomes in ALS Patients at TidalHealthRecruitingNCT07491484
- Characterization of Platelet Molecular Profiles in ALS for the Identification of Specific Diagnostic Biomarkers - A Pilot StudyNot yet recruitingNCT07479017
- Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular DiseaseRecruitingNCT07478172Not applicable
- Virtual Reality for Anxiety Management in Persons With Amyotrophic Lateral SclerosisNot yet recruitingNCT07473765Not applicable
- Research of Traditional Chinese Medicine Oral Preparation of C. Cicadae in the Treatment of ALS Patients With Elevated Plasma SphingolipidsNot yet recruitingNCT07467746Phase 2
- Invasive Home Ventilation in DenmarkRecruitingNCT07467187
- Do Video Recordings of Multidisciplinary Clinics Improve Quality of Life for People With ALS and Their Caregivers?RecruitingNCT07454733Not applicable
- Personalized Antisense Oligonucleotide Therapy for A Single Patient With CHCHD10 ALS (nL18576)Not yet recruitingNCT07423494Phase 1/2
- Evaluation of the Combined Therapy of EH-301 and N-acetylcysteine Together With Riluzole in Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07414212Phase 1/2
- Clinical Outcome Assessment for AT & BCIRecruitingNCT07407725Not applicable
- Safety and Tolerability Study of CTx1000 In Participants With Amyotrophic Lateral SclerosisRecruitingNCT07401121Phase 1
- Healey ALS MyMatch Common Screening ProtocolNot yet recruitingNCT07400393
- Kamlanoflast In Amyotrophic Lateral SclerosisNot yet recruitingNCT07396818Phase 1/2
- MND Together: Phase 1Not yet recruitingNCT07393932
- Quantification of Hsp90 in the Human BrainRecruitingNCT07380204Not applicable
- A Clinical Trial to Evaluate NB-4746 in Participants With Amyotrophic Lateral Sclerosis.RecruitingNCT07369076Phase 1/2
- Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)RecruitingNCT07357428Not applicable
- A Physiotherapy Intervention Study in Patients With Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07341984Not applicable
- Digital Speech Markers for Monitoring ALS in Spanish SpeakersNot yet recruitingNCT07341334
- Identifying Biomarkers in ALS Patients Using Neuronal Derived Extracellular VesiclesRecruitingNCT07334743
- Efficacy and Safety of Tazbentetol in ALS ParticipantsNot yet recruitingNCT07325591Phase 2/3
- Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALSRecruitingNCT07322003Phase 3
- This Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic SignalingNot yet recruitingNCT07321860Phase 2/3
- LONgitudinal and Integrated Evaluation of Biomarkers in reLation to phenotYpe in ALSRecruitingNCT07312240Not applicable
- Needs of ALS Patients With C9orf72 Mutation and Their CaregiversRecruitingNCT07302321
- Impact of Robotic Glove Use on Quality of Life, Grip Strength and Fine Motor Control in ALSEnrolling by invitationNCT07298486Not applicable
- Tongue-strengthening Exercises in People With ALS.RecruitingNCT07295990Not applicable
- Tofersen in Non-SOD1 ALSRecruitingNCT07294144Phase 2
- Video-Based Proprioceptive Exercise Program in ALSRecruitingNCT07292545Not applicable
- A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07290062Phase 1
- Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALSRecruitingNCT07287397Phase 1/2
- Translating Single-cell Vulnerability Into Novel ALS Biomarkers and Therapeutic Targets: Towards a Liquid Nerve BiopsyRecruitingNCT07268833
- A Study to Learn More About the Long-Term Safety of Tofersen (Qalsody) in Participants With Superoxide Dismutase 1 (SOD-1) Amyotrophic Lateral Sclerosis (ALS)RecruitingNCT07259980
- Lung Insufflation Capacity Training and Respiratory Function in Amyotrophic Lateral SclerosisRecruitingNCT07257302Not applicable
- Omics Sciences for the Identification of Pathogenetic Mechanisms and Biomarkers in Neurodegenerative DiseasesRecruitingNCT07235111
- Healing ALS Registry Observational Study (HAROS)RecruitingNCT07233148
- Effect of Terazosin on ATP Levels in People With Amyotrophic Lateral SclerosisRecruitingNCT07224269Early Phase 1
- VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication RestorationRecruitingNCT07224256Not applicable
- Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral SclerosisRecruitingNCT07221240Phase 1
- Identification of Early Markers for ALSRecruitingNCT07213440Not applicable
- Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple Vision ProNot yet recruitingNCT07209943Not applicable
- Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)RecruitingNCT07204977Phase 1
- Integrating Metabolism, Connectivity, and Mesoscale Imaging at Ultra-high Field to Decipher Mechanisms of Resilience and Neurodegeneration in Neurological Diseases and Healthy AgingRecruitingNCT07202494
- Investigating the Impact of Electrical Stimulation on Facial Pain, Jaw Movement and Oral Health in People With Motor Neuron Disease.RecruitingNCT07187388Not applicable
- Polish Version Dyspnea in Amyotrophic Lateral SclerosisNot yet recruitingNCT07178574
- Amyotrophic Lateral Sclerosis Registry in ThailandRecruitingNCT07175935
- Efficacy and Safety of Masitinib in Combination With SoC Versus Placebo in the Treatment of ALS PatientsNot yet recruitingNCT07174492Phase 3
- Dynamic Impact of NIV on Diaphragmatic Ultrasound in Patients With Amyotrophic Lateral SclerosisNot yet recruitingNCT07170865
- A Phase Ⅰ/Ⅱa Study of SNUG01 in Adult Subjects With ALSNot yet recruitingNCT07169175Phase 1/2
- PHENOGENE-1A (Cromolyn) Treatment in Patients With Mild to Moderate ALSRecruitingNCT07142291Phase 2
- FHND1002 for ALS Treatment: Phase 2Not yet recruitingNCT07138014Phase 2
- Telehealth in MND-Research (TIM-R): A Research Database for MNDRecruitingNCT07132879
- GB-PRIME: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for the Control of External DevicesRecruitingNCT07127172Not applicable
- The Safety, Tolerability and Preliminary Efficacy of Derived Motor Neuron Progenitor Cells (XS228CN) in Subjects With Amyotrophic Lateral SclerosisRecruitingNCT07118319Phase 1
- A Study of LY4256984 in Participants With Sporadic Amyotrophic Lateral SclerosisRecruitingNCT07100119Phase 1
- Generation of Cell Banks and Biomarker Isolation From Patients With Amyotrophic Lateral Sclerosis (ALS) (HCD-SLA)Not yet recruitingNCT07099066
- Personalized Antisense Oligonucleotide for Participants With CHCHD10 ALSEnrolling by invitationNCT07095686Phase 1/2