An observational study in Alcohol Use, Alcohol Consumption and Menstrual Cycle, sponsored by Hospices Civils de Lyon. Not yet recruiting at 1 site in France. Open to female participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-03.
Sponsored by Hospices Civils de Lyon · Observational
The FLOW study aims to assess the association between menstrual cycle phases and alcohol consumption in women from the general population. Hormonal fluctuations throughout the menstrual cycle may influence alcohol use behaviors, anxiety levels, physical activity, and sleep quality. Participants will be followed prospectively for three consecutive menstrual cycles through monthly questionnaires assessing alcohol consumption, anxiety, physical activity, and sleep.
Alcohol consumption among women has increased in recent years and represents a major public health concern. Emerging evidence suggests that ovarian hormones may influence vulnerability to substance use and addictive behaviors. The menstrual cycle provides a physiological model to investigate the effects of hormonal fluctuations on alcohol consumption patterns.
FLOW is a prospective, longitudinal, observational cohort study designed to evaluate the relationship between menstrual cycle phases and alcohol consumption in women with regular menstrual cycles. Participants will complete online self-administered questionnaires at baseline (Month 1) and during two subsequent monthly follow-up assessments (Month 2 and Month 3).
Data collected include menstrual cycle characteristics, alcohol use assessed using the Alcohol Timeline Followback (A-TLFB), anxiety symptoms measured by the Generalized Anxiety Disorder-7 scale (GAD-7), physical activity assessed using the International Physical Activity Questionnaire-Short Form (IPAQ-SF), and sleep quality assessed using the Mini Sleep Questionnaire (MSQ).
940 studies on the registry are indexed under Alcohol Drinking; 171 are open to participants now.
This study's planned enrollment of 2,000 is above the median of 227 across 94 observational studies indexed under Alcohol Drinking.
Browse Alcohol Drinking studies →Hospices Civils de Lyon is the lead sponsor of 1,863 studies on the registry; 445 are open to participants now.
Compared within Alcohol Drinking, the registry's first condition term, which may not be this study's main condition. Counted across the registry records on this site, refreshed daily. How we classify →
Women from the general population with regular menstrual cycles.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Occurrence of an alcohol consumption day
Assessment of whether alcohol was consumed (Yes/No), measured using the Alcohol Timeline Followback (A-TLFB) over the previous 7 days, across three menstrual cycles
Time frame: Up to 3 months
Number of binge drinking days
Number of days with excessive alcohol consumption during the previous 7 days, assessed using A-TLFB. Excessive alcohol consumption is defined as at least six standard drinks consumed on a given day.
Time frame: Up to 3 months
Association between alcohol consumption and anxiety levels over time
Correlation between average alcohol consumption and anxiety levels assessed using GAD-7 throughout the menstrual cycle.
Time frame: Up to 3 months
Association between alcohol consumption and physical activity over time
Correlation between average alcohol consumption and physical activity assessed using IPAQ-SF.
Time frame: Up to 3 months
Association between alcohol consumption and sleep quality over time
Correlation between average alcohol consumption and sleep quality assessed using the Mini Sleep Questionnaire (MSQ)
Time frame: Up to 3 months
Association between alcohol consumption and contraceptive method
Comparison of alcohol consumption patterns according to contraceptive method used.
Time frame: Up to 3 months
Start is estimated for Feb 2027; primary completion for May 2027, 3 months later.
Of 50 non-industry observational studies under Alcohol Drinking, half reached primary completion within 45 months of starting (the median), counting those still running; a quarter within 25 and three quarters within 65. This study's planned 3 months is below that.
Counting every sponsor, half of 50 studies reached it within 45 months; a quarter within 25 and three quarters within 65.
Since we started tracking on Sep 25, 2026, the dates moved once, on Nov 3, 2026: start Jan 2027 → Feb 2027, primary completion Apr 2027 → May 2027 and completion Apr 2027 → May 2027.
Earlier changes are on the record history on ClinicalTrials.gov ↗
How these figures are worked out, and which studies are left out of them.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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