ClinicalTrials.gg
Not yet recruitingNCT07847086Updated Oct 1, 2026

Gait Pattern and Its Relation to Cognition and VEP in Multiple Sclerosis

An observational study in Multiple Sclerosis and Gait Disorders, Neurologic, sponsored by Assiut University. Not yet recruiting. Open to participants aged 18 Years to 55 Years. Per ClinicalTrials.gov, last updated 2026-10-01.

Sponsored by Assiut University · Observational

Updated Sep 29, 2026Newly registeredGo to Updates ↓

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Study type
Observational
Model
Case-only
Time perspective
Cross-sectional
Enrollment
70
Ages
18 Years to 55 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-14

Among 26 studies in Multiple Sclerosis by Assiut University — 15 open to participants now, 15 under way, none of them phase 3. Multiple Sclerosis · Assiut University.

Planned enrollment
15th of 24
70 · median 100
Started
2026
with 5 others
Observational
24 of 26
15 open now
Primary completion
2027-09
later than 8 of 14 live
Registered
25th of 26
by date

Among the 26 studies in Multiple Sclerosis by Assiut University, this one is the 15th largest by planned enrollment of the 24 observational ones that give a count, is one of 6 that started in 2026, is one of 24 observational ones, reaches primary completion later than 8 of the 14 other live ones, and was the 25th registered.

Multiple Sclerosis

3,269 studies on the registry are indexed under Multiple Sclerosis; 663 are open to participants now.

Browse Multiple Sclerosis studies →

Open to participants now

15 of the 26 studies in Multiple Sclerosis by Assiut University are open now, in 1 country. Recruiting first, the newest first:

9 more — sign in →

By country, each count listing its studies:

All 15 open studies →

Where they have run

Who these studies take

Of the 431 Multiple Sclerosis studies recruiting now, 163 (38%) set no upper age limit and 212 (49%) stop at 75 or younger; 40 take children under 18; 96 take healthy volunteers.

This study: 18 Years to 55 Years · all sexes · no healthy volunteers.

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02

Study summary

This cross-sectional study aims to assess the pattern of gait in patients with multiple sclerosis and to evaluate its relation to cognitive function, visual evoked potentials, and radiological findings.

Read the detailed description

Gait impairment is a common and disabling feature of multiple sclerosis. This observational study will include patients with confirmed multiple sclerosis according to the revised McDonald criteria who are clinically stable.

Participants will undergo quantitative gait analysis, cognitive assessment, visual evoked potential testing, and review of MRI findings in a single assessment visit.

03

Conditions studied

  • Multiple Sclerosis
  • Gait Disorders, Neurologic

Keywords

  • Visual evoked potentials
  • Multiple sclerosis
  • Gait analysis
  • Cognition
  • Assiut
04

Who can participate

Ages eligible
18 Years to 55 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients with multiple sclerosis attending the Neurology Department outpatient clinic and gait laboratory at Assiut University.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • - Age 18 to 55 years
  • Confirmed diagnosis of multiple sclerosis according to the revised McDonald criteria
  • Clinically stable (no relapse or treatment within 4 weeks)
  • Able to walk independently with or without a single assistive device
  • Written

Exclusion criteria

Exclusion Criteria:

  • - Other neurological, orthopedic, visual, or vestibular conditions affecting gait
  • Severe cognitive impairment precluding valid testing
  • Pregnancy
  • MRI
  • Ocular disease unrelated to multiple sclerosis
Terms in these criteria, in plain language(3)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Corticosteroids (steroids)

Anti-inflammatory medicines such as prednisone, prednisolone and dexamethasone — not the anabolic steroids used for muscle.

Studies differ in what they allow: check which steroid medicines, routes (tablets, injections, creams, inhalers, eye drops) and doses this study accepts.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

Contraindication

A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.

05

Study design

Observational model
Case-only
Time perspective
Cross-sectional
Enrollment
70 participants (estimated)
Patient registry
No

Groups and cohorts

  • Single cohort: Multiple Sclerosis Patients

    Patients with confirmed multiple sclerosis who will undergo gait analysis, cognitive testing, visual evoked potential assessment, and MRI review in a single visit.

06

What researchers measure

Primary outcomes

  1. Mean gait velocity

    Mean gait velocity in meters per second measured by quantitative spatiotemporal gait analysis.

    Time frame: Baseline

Secondary outcomes

  1. Mean cadence

    Mean cadence in steps per minute measured by quantitative gait analysis.

    Time frame: Baseline

  2. Mean stride length

    Mean stride length in centimeters measured by quantitative gait analysis.

    Time frame: Baseline

  3. Mean MoCA score

    Mean Montreal Cognitive Assessment (MoCA) score (range 0-30, higher scores indicate better cognition).

    Time frame: Baseline

  4. Mean P100 latency

    Mean P100 latency in milliseconds measured by pattern-reversal visual evoked potentials.

    Time frame: Baseline

  5. Mean EDSS score

    Mean Expanded Disability Status Scale (EDSS) score (range 0-10, higher scores indicate worse disability).

    Time frame: Baseline

07

Study locations

No study locations are listed for this record.

08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

2 registry updates since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reached

Start is estimated for Sep 2026; primary completion for Sep 2027, 12 months later.

How these figures are worked out, and which studies are left out of them.

Registered
Sep 23, 2026
First posted
Sep 29, 2026
StartEst.
Sep 26, 2026
Primary completionEst.
Sep 26, 2027
CompletionEst.
Mar 1, 2028
Last update
Oct 1, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Secondary outcomes
1 description edited
What changed in the outcomes
  • DescriptionMean EDSS score: how it is measured was reworded
Oct 1, 2026
Registered
First appeared on the registry
Sep 29, 2026
Show all 2 updates
  1. Oct 1, 2026
    Secondary outcomes 1 description edited
    What changed in the outcomes
    • DescriptionMean EDSS score: how it is measured was reworded
  2. Sep 29, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07847086
Lead sponsor
Assiut University
Responsible party
Manar Moataz Abdel-ghani (Resident Physician, Department of Neuropsychiatry, Assiut University) — Principal investigator
First posted
Sep 29, 2026
Start date
Sep 26, 2026 (estimated)
Primary completion
Sep 26, 2027 (estimated)
Completion
Mar 1, 2028 (estimated)
Last update
Oct 1, 2026

Study contacts

Manar A Ali, Resident
Contact
manarmoataz2000@gmail.com
01091423914
Tarek A Rageh, prof
study chair · Neuropsychiatry Department, Assiut University Hospitals

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Sep 2026. You cannot join it, but the record below documents what was studied.

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Discussion

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