ClinicalTrials.gg
Not yet recruitingNCT07936344REHDUpdated Nov 13, 2026

Effect of Resistance Exercise in Hemodialysis Patients

An interventional study of Resistance Exercise Training in Hemodialysis, sponsored by Assiut University. Not yet recruiting at 1 site in Egypt. Open to participants aged 16 Years to 59 Years. Per ClinicalTrials.gov, last updated 2026-11-13.

Sponsored by Assiut University · Not applicable, Interventional, and Treatment

Updated Nov 13, 2026Newly registeredGo to Updates ↓

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Phase
Not applicable
Study type
Interventional
Enrollment
104
Allocation
Randomized
Ages
16 Years to 59 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-13

Among 18 studies in Kidney Failure, Chronic by Assiut University — 9 open to participants now, 9 under way, none of them phase 3. Kidney Failure, Chronic · Assiut University.

Started
2027
the only one that year
No phase
4 of 18
3 open now
Registered
18th of 18
by date

Among the 18 studies in Kidney Failure, Chronic by Assiut University, this one is the only one that started in 2027, is one of 4 with no phase, and was the 18th registered.

Kidney Failure, Chronic

2,109 studies on the registry are indexed under Kidney Failure, Chronic; 273 are open to participants now.

Browse Kidney Failure, Chronic studies →

Open to participants now

9 of the 18 studies in Kidney Failure, Chronic by Assiut University are open now, in 1 country. Recruiting first, the newest first:

3 more — sign in →

By country, each count listing its studies:

All 9 open studies →

Where they have run

Who these studies take

Of the 169 Kidney Failure, Chronic studies recruiting now, 109 (64%) set no upper age limit and 32 (19%) stop at 75 or younger; 18 take children under 18; 22 take healthy volunteers.

This study: 16 Years to 59 Years · all sexes · no healthy volunteers.

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02

Study summary

This study aims to evaluate the effect of a resistance exercise program on patients undergoing hemodialysis, assessing its impact on physical performance, health-related quality of life and overall clinical outcomes

Read the detailed description

This study is designed as a clinical investigation to assess the comprehensive effects of structured resistance exercise training in patients receiving hemodialysis. The protocol involves implementing a supervised exercise regimen to evaluate key physiological and clinical endpoints, including changes in muscle strength, functional capacity, biochemical markers, and overall health-related quality of life. Regular monitoring and assessments will be conducted throughout the study period to track patient progress, safety, and intervention efficacy.

03

Conditions studied

  • Hemodialysis

Keywords

  • Hemodialysis, Resistance Exercise, End-Stage Renal Disease, Physical Performance, Rehabilitation
04

Who can participate

Ages eligible
16 Years to 59 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age > 18 years.
  • Diagnosed with ESRD and on maintenance hemodialysis for at least 3 consecutive months.
  • Receiving haemodialysis 3 times/week.
  • A participant completing ≥80% of scheduled sessions will be considered adherent.
  • Clinically stable for a predefined period.
  • Able to stand and walk sufficiently to perform functional tests.
  • Stable vascular access.
  • Adequate cognitive ability to understand the instructions.
  • Capable of providing informed written consent.

Exclusion criteria

Exclusion Criteria:

  • Unstable angina or severe uncompensated cardiovascular disease.
  • Severe musculoskeletal, neurological or orthopedic limitations preventing exercise.
  • Severe symptomatic anemia ( \< 8 g/dL) not responsive to therapy.
  • Active infection or acute systemic illness.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Hemoglobin (Hb)

The protein in red blood cells that carries oxygen. A low level is anaemia, which can cause tiredness and breathlessness. Measured in g/dL or g/L (9 g/dL is 90 g/L).

05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
104 participants (estimated)

Study arms

  • Experimental
    Resistance Exercise Group

    Patients in this group will participate in a structured resistance exercise training program during or between hemodialysis sessions.

    Behavioral: Resistance Exercise Training

  • No intervention
    Control Group

    Patients in this group receive standard care and lifestyle advice during maintenance hemodialysis without participating in the structured resistance exercise program.

Interventions

  • BehavioralResistance Exercise Training

    Participants will undergo a structured resistance training program using specific weights or elastic bands. The exercise sessions will be performed under supervision to ensure safety and adherence, targeting major muscle groups to improve physical fitness and strength.

06

What researchers measure

Primary outcomes

  1. Change in Muscle Strength

    Evaluation of muscle strength improvement measured using standard assessment tools (such as dynamometry) before and after the intervention.

    Time frame: 6 months

07

Study locations

1 site
  • Assiut University Hospitals
    Asyut, Egypt
    • Amira Mahrous Resident Physician, M.B.B.Ch · Contact+201147569434
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Start is estimated for Jan 2027; primary completion for Jul 2027, 6 months later.

Of 347 non-industry interventional studies with no phase under Kidney Failure, Chronic, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 8 and three quarters within 47. This study's planned 6 months is below that.

Counting every sponsor, half of 425 studies reached it within 22 months; a quarter within 8 and three quarters within 46.

How these figures are worked out, and which studies are left out of them.

Registered
Nov 7, 2026
First posted
Nov 13, 2026
StartEst.
Jan 15, 2027
Primary completionEst.
Jul 15, 2027
CompletionEst.
Aug 15, 2027
Last update
Nov 13, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Registered
First appeared on the registry. No changes since
Nov 13, 2026
Show all 1 update
  1. Nov 13, 2026
    First appeared on the registry

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT07936344
Lead sponsor
Assiut University
Responsible party
Amira Mahrous Hussein Ali (Resident Physician, Assiut University) — Principal investigator
First posted
Nov 13, 2026
Start date
Jan 15, 2027 (estimated)
Primary completion
Jul 15, 2027 (estimated)
Completion
Aug 15, 2027 (estimated)
Last update
Nov 13, 2026

Study contacts

Amira Mahrous Hussein, M.B.B.Ch
Contact
amiramahrous65@yahoo.com
+201147569434
Alshaimaa Sayed Hassan, lecturer
Contact
shaimaa_nephro@aun.edu.eg
+20 10 96883911
Nabila Fayek Amin, professor
principal investigator · Assiut University

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.

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