An observational study in Aortic Coarctation, sponsored by Assiut University. Not yet recruiting. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2026-11-09.
Sponsored by Assiut University · Observational
This cross-sectional study aims to evaluate left ventricular and left atrial strain parameters in patients at least one year after aortic coarctation stenting compared with healthy controls.
Coarctation of the aorta is a congenital heart disease that can cause chronic pressure overload and cardiac remodeling. Speckle-tracking echocardiography allows measurement of myocardial deformation parameters such as global longitudinal strain and left atrial strain.
This observational study will assess cardiac structure and function using conventional and speckle-tracking echocardiography in patients who underwent aortic coarctation stenting at least one year earlier, and will compare the findings with age- and sex-matched healthy controls. Exercise blood pressure response will also be evaluated.
49 studies on the registry are indexed under Aortic Coarctation; 16 are open to participants now.
This study's planned enrollment of 80 is below the median of 100 across 29 observational studies indexed under Aortic Coarctation.
Browse Aortic Coarctation studies →Assiut University is the lead sponsor of 5,078 studies on the registry; 2,178 are open to participants now.
Of its 14 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients who underwent aortic coarctation stenting at least one year earlier and age-, sex-, and body-weight-matched healthy controls at Assiut University Heart Hospital.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Patients who underwent aortic coarctation stenting at least one year earlier.
Age-, sex-, and body-weight-matched healthy individuals.
Left ventricular global longitudinal strain
Mean left ventricular global longitudinal strain measured by speckle-tracking echocardiography (percentage, more negative values indicate better systolic function).
Time frame: Baseline
Left atrial reservoir strain
Mean left atrial reservoir strain measured by speckle-tracking echocardiography (percentage).
Time frame: Baseline
Left ventricular ejection fraction
Mean left ventricular ejection fraction measured by echocardiography (percentage).
Time frame: Baseline
Number of patients with exercise-induced hypertension
Number of patients who develop exercise-induced hypertension defined as peak exercise systolic blood pressure ≥190 mmHg in females or ≥210 mmHg in males, or a rise ≥50 mmHg from baseline.
Time frame: Baseline
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗
This study is not yet recruiting, as verified in Nov 2026. You cannot join it, but the record below documents what was studied.
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