Clinical trials in Lesotho
42 studies list at least one site in Lesotho. 3 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-16.
Status
- Completed
- 31
- Active, not recruiting
- 4
- Recruiting
- 3
- Status unknown
- 2
- Withdrawn
- 1
- Terminated
- 1
Phase
- Phase 3
- 4
- Phase 4
- 1
Most studied here
Who runs them
University Hospital, Basel, Switzerland (8) · Swiss Tropical & Public Health Institute (7) · Columbia University (6) · University of Nairobi (2) · Elizabeth Glaser Pediatric AIDS Foundation (2) · Médecins Sans Frontières, France (2) · Klaus Reither (2) · Niklaus Labhardt (2)
Studies
Recruiting first, then most recently updated. Showing 42 of 42 — search for more.
- Community-Based Chronic Disease Care in Rural LesothoRecruitingNCT05596773
- Ndovu RCT: Investing the Optimal Management of Dolutegravir ResistanceRecruitingNCT06747507Phase 3
- Investigating the Optimal Management of Dolutegravir ResistanceRecruitingNCT06762054
- ComBaCaL HIV Prevention TwiCsWithdrawnNCT07581600Not applicable
- Community-based, eHealth Supported Type 2 Diabetes Care by Lay Village Health Workers in Rural LesothoActive, not recruitingNCT05743387Not applicable
- Characteristics and Outcomes of Patients Who Received Etravirine and/or DarunavirCompletedNCT04194021
- Closing -TB GAPs - for People Living With HIV: TB Guidance for Adaptable Patient-Centered ServiceActive, not recruitingNCT05342064Not applicable
- "Community-based, eHealth Supported Management of Cardiovascular Risk Factors by Lay Village Health Workers (ComBaCaL aHT TwiC 1 & ComBaCaL aHT TwiC 2)Active, not recruitingNCT05684055Not applicable
- Diagnostic Accuracy of CAD4TB and C-reactive Protein Assay as Triage Tests for Pulmonary TuberculosisCompletedNCT04666311
- Tuberculosis Diagnostic Trial of CAD4TB Screening Alone Compared to CAD4TB Screening Combined With a CRP Triage Test, Both Followed by Confirmatory Xpert MTB/RIF Ultra in Communities of Lesotho and South AfricaCompletedNCT05526885Not applicable
- Viral Load Triggered ART Care in LesothoCompletedNCT04527874Not applicable
- Same-day Versus Rapid ART Initiation in HIV-positive Individuals Presenting With Symptoms of TuberculosisCompletedNCT05452616Not applicable
- The CATALYST StudyTerminatedNCT05937698
- Substituting SMSs for Provider-delivered Care to Improve Alcohol Use OutcomesCompletedNCT05925270Not applicable
- Evaluating Newly Approved Drugs for Multidrug-resistant TBCompletedNCT02754765Phase 3
- Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)CompletedNCT03896685Phase 3
- Tolerability of Lopinavir Versus Dolutegravir for Children and Adolescents Living With HIVCompletedNCT05426421
- Strengthening Evidence on Optimal Multidrug-resistant Tuberculosis Treatment RegimensActive, not recruitingNCT05871489
- Measuring Anticipated Attitudes and Behavior Towards a New Medical Treatment in LesothoCompletedNCT06246058
- Genotype-Informed Versus Empiric Management of VirEmiaCompletedNCT04233242Not applicable
- PROvide MIner-friendly SErvices for Integrated TB/HIV Care in Lesotho StudyCompletedNCT03537872Not applicable
- Nthabi in Lesotho - ImplementationCompletedNCT04354168Not applicable
- Dolutegravir in Real Life in LesothoCompletedNCT04238767
- TB Innovation Project: A Pre- and Post- Implementation Assessment (TIPPI)CompletedNCT03948698
- Pharmacometrics to Advance Novel Regimens for Drug-resistant Tuberculosis-PandrTB TuberculosisStatus unknownNCT03827811
- Identifying Most Effective Treatment Strategies to Control Arterial Hypertension in Sub-Saharan AfricaCompletedNCT04129840Not applicable
- Expand New Drugs for TB [endTB]CompletedNCT03259269
- Preventing Childhood Tuberculosis in Lesotho (PREVENT Study)CompletedNCT02662829Not applicable
- "Switch Either Near Suppression Or THOusand"CompletedNCT03088241Not applicable
- Start TB Patients on ART and Retain on Treatment (START Study)CompletedNCT01872390Not applicable
- Peer-Educator-coordinated vs Nurse-coordinated ART Refill for Adolescents and Young Adults Living With HIV in LesothoCompletedNCT03969030Not applicable
- Village-based vs Clinic-based ART Care - a Cluster Randomized Controlled Trial in LesothoCompletedNCT03630549Phase 4
- Short Adherence Intervention for Viral Re-suppressionCompletedNCT03242980Not applicable
- HOme-based SElf-testiNG - a Cluster Randomized Controlled Trial in Rural Lesotho (HOSENG)CompletedNCT03598686Not applicable
- Same-day ART Initiation Versus Standard of Care After Positive HIV-test Result in Rural LesothoCompletedNCT02692027Phase 3
- Outcomes of Differentiated Models of Antiretroviral Treatment (ART) ProvisionStatus unknownNCT03438370Not applicable
- Comorbidities and Virologic Outcome Among Patients on Anti-retroviral Therapy in Rural LesothoCompletedNCT02126696
- Reducing Lesbian, Gay , Bisexual and Transgender (LGBT) Stigma in Swaziland and LesothoCompletedNCT02410434Not applicable
- Enhanced Prevention in Couples: Feasibility Study #2CompletedNCT02027441
- Enhanced HIV Prevention in Couples: Feasibility Study #1CompletedNCT02027714
- Enhanced HIV Prevention in Couples: Feasibility Study #3CompletedNCT02027519
- Comparison of Door-to-door Versus Community Gathering to Provide HIV Counseling and Testing Services in Rural LesothoCompletedNCT01459120Not applicable