Warfarin clinical trials
Also written Coumadin and Jantoven.
How each study uses Warfarin is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Warfarin studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Approvals
The first approval found in each region, with its record
- United States
- 8 Jun 1954 · COUMADIN · NDA 009218 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
139 studies that test it; most in 2016 (12)
| Year | Studies |
|---|---|
| 1993 | 1 |
| 1998 | 2 |
| 1999 | 4 |
| 2000 | 2 |
| 2002 | 3 |
| 2003 | 1 |
| 2004 | 1 |
| 2005 | 6 |
| 2006 | 4 |
| 2007 | 8 |
| 2008 | 5 |
| 2009 | 11 |
| 2010 | 11 |
| 2011 | 6 |
| 2012 | 4 |
| 2013 | 2 |
| 2014 | 8 |
| 2015 | 11 |
| 2016 | 12 |
| 2017 | 6 |
| 2018 | 9 |
| 2019 | 6 |
| 2020 | 1 |
| 2021 | 3 |
| 2022 | 2 |
| 2023 | 4 |
| 2024 | 3 |
| 2025 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 33 · Other 109
AstraZeneca (5) · Boehringer Ingelheim (4) · Hadassah Medical Organization (3) · Hamilton Health Sciences Corporation (3) · Institute for Clinical and Experimental Medicine (3) · Novo Nordisk A/S (2) · Eli Lilly and Company (2) · University of California, San Francisco (2)
Often tested with
Tested in the same studies.
Rivaroxaban (17) · Apixaban (11) · Aspirin (10) · Midazolam (8) · Dabigatran (7) · Edoxaban (6) · Omeprazole (6) · Caffeine (5)
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Tested against it · 5 phase 3 studies under way
Warfarin is the comparator. A study of two new drugs counts under both.
- 3Rivaroxaban · Second Affiliated Hospital, School of Medicine, Zhejiang University, Rawalpindi Institute of Cardiology · next primary completion Apr 2027
- 2Apixaban · Columbia University, University of Arizona · next primary completion Jul 2028
Reaching primary completion within a year · 3
Studies that test Warfarin.
- Dec 2026Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese ParticipantsPhase 1 · Beijing QL Biopharmaceutical Co.,Ltd
- Dec 2026Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail ApproachEarly Phase 1 · Washington State University
- Jan 2027The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on DialysisPhase 4 · Nicholas Carlson
Studies
Open first, then newest update. How each study uses Warfarin is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 142
- Low INR to Minimize Bleeding With Mechanical Valves TrialRecruitingPhase 3Population Health Research InstituteNCT03636295Written as Warfarin
- Assessment of TRanscathetEr and Surgical Aortic BiOprosthetic Valve Thrombosis and Its TrEatment With AnticoagulationRecruitingNot applicableCedars-Sinai Medical CenterNCT02318342Written as Warfarin
- Evaluating the Pharmacokinetics of Oregano and Potential Oregano-drug Interactions Using a Drug Cocktail ApproachRecruitingEarly Phase 1Washington State UniversityNCT06693960Written as Drug cocktail
- The Danish Warfarin-Dialysis Study - Safety and Efficacy of Warfarin in Patients With Atrial Fibrillation on DialysisRecruitingPhase 4Nicholas CarlsonNCT03862859Written as Warfarin
- Vitamin K for Perioperative Warfarin ManagementRecruitingPhase 4University of MichiganNCT07515664Written as Warfarin (standard without loading)
- Antithrombotic Therapy After Coronary Artery Bypass Grafting Combined With Coronary EndarterectomyRecruitingPhase 4China National Center for Cardiovascular DiseasesNCT05782270Written as Warfarin
- Trial of Low-intensity Anticoagulation to Reduce GI or Other Bleeding Complications With Equivalent Therapeutic Efficacy in HeartMate 3 LVAD PatientsNot yet recruitingPhase 4Asan Medical CenterNCT07081035Written as Warfarin (low-intensity anticoagulation)
- Use of Warfarin After the First Trimester in Pregnant Women With APSRecruitingPhase 4Mohamed Sayed AbdelhafezNCT02303171Written as Warfarin
- Drug-drug Interaction Study of ZT002 Injection in Overweight and Obese ParticipantsActive, not recruitingPhase 1Beijing QL Biopharmaceutical Co.,LtdNCT07550816Written as ZT002 injection, metformin, warfarin
- Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee ReplacementCompletedPhase 4Dartmouth-Hitchcock Medical CenterNCT02810704Written as Warfarin
- A Study on How CagriSema Affects Levels of Atorvastatin and Warfarin in the Blood of Participants With Excess Body WeightCompletedPhase 1Novo Nordisk A/SNCT06289504Written as Warfarin
- Clinical Application of Simcyp-Guided Warfarin Initiation Doses in Cirrhotic Patients With Portal Vein ThrombosisCompletedPhase 4Kafrelsheikh UniversityNCT07571460Written as Warfarin 3 mg
- Efficacy and Safety of Oral Rivaroxaban in Cerebrosinovenous ThrombosisCompletedNot applicableMuhammad Aamir LatifNCT07523347Written as Warfarin
- A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver CirrhosisCompletedNot applicableBoehringer IngelheimNCT05741385Written as Warfarin sodium
- COMPARISON OF WARFARIN AND RIVAROXABAN IN THE TREATMENT OF LOWER LIMB DEEP VENOUS THROMBOSISCompletedPhase 1Children Hospital and Institute of Child Health, LahoreNCT07077954Written as Warfarin
- The Nordic Aortic Valve Intervention Trial 4 (NOTION-4)Active, not recruitingNot applicableRigshospitalet, DenmarkNCT06449469Written as Warfarin
- Apixaban, Warfarin and Aspirin Prevents Portal Vein Thrombosis in Patients After Laparoscopic Splenectomy(ESAWAAPT)CompletedPhase 4Northern Jiangsu People's HospitalNCT04645550Written as Warfarin
- Rivaroxaban Versus Warfarin in the Evaluation of Progression of Coronary CalciumCompletedPhase 4Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical CenterNCT02376010Written as Warfarin
- LV Thrombus After Acute AMI: A Randomized Controlled TrialTerminatedNot applicableAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)NCT01556659Written as Absence of vitamin K antagonist
- Clinical Trial to Investigate Safety and Efficacy of Edoxaban in Patients With CTEPH (KABUKI)CompletedPhase 3Kyushu UniversityNCT04730037Written as Warfarin Potassium
See all 142 studies that test Warfarin →
Given beside what is tested · 68 — Warfarin is usual care or a partner of the new treatment
- Phase I Drug-Drug Interaction Study of UBT251 Injection in Participants With Overweight or ObesityRecruitingPhase 1The United Bio-Technology (Hengqin) Co., Ltd.NCT07785934Written as Warfarin Sodium
- Aspirin Monotherapy Versus Sequential Warfarin-Aspirin Therapy After TAVR in Patients With Pure Aortic RegurgitationRecruitingNot applicableShanghai Zhongshan HospitalNCT07677410Written as Warfarin
- Determinants of Warfarin MetabolismRecruitingNot applicableHadassah Medical OrganizationNCT00162474Written as Warfarin
- Influence of HDM1005 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and DigoxinNot yet recruitingPhase 1Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.NCT07502001Written as Warfarin
- Aspirin and Hemocompatibility Events in Chronic Advanced Heart Failure Patients With Assist DeviceRecruitingPhase 4Columbia UniversityNCT06655376Written as Warfarin
- A Drug-Drug Interaction Study of HDM1002 and Metformin, Empagliflozin, Midazolam, Valsartan, and WarfarinRecruitingPhase 1Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.NCT07331389Written as Warfarin
- Study on Gastric Emptying Effect and Drug-Drug Interactions of GZR18 InjectionCompletedPhase 1Gan & Lee Pharmaceuticals.NCT07128888Written as GZR18 injection,digoxin tablets, rosuvastatin calcium tablets and warfarin sodium tablets
- A Study to Evaluate the Effect of Multiple Doses of JNJ-56021927 on the Pharmacokinetics of Multiple Cytochrome P450 and Transporter Substrates in Participants With Castration-Resistant Prostate CancerActive, not recruitingPhase 1Aragon Pharmaceuticals, Inc.NCT02592317Written as Drug Cocktail
- A Study of BGM0504 in Overweight or Obese ParticipantsCompletedPhase 1BrightGene Bio-Medical Technology Co., Ltd.NCT06920056Written as Warfarin
- Interaction of BI 425809 With Midazolam, Warfarin, Omeprazole and DigoxinCompletedPhase 1Boehringer IngelheimNCT02783040Written as Warfarin
- Sunitinib or Cediranib for Alveolar Soft Part SarcomaCompletedPhase 2National Cancer Institute (NCI)NCT01391962Written as Warfarin
- Drug-durg Interaction of RAY1225 With Warfarin, Atorvastatin, Metformin and DigoxinActive, not recruitingPhase 1Guangdong Raynovent Biotech Co., LtdNCT07362030Written as Warfarin Sodium Tablets
- Pemvidutide (ALT-801) DDI Study in Healthy VolunteersCompletedPhase 1Altimmune, Inc.NCT04972396Written as Warfarin
- Influence of HRS9531 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin in Healthy SubjectsCompletedPhase 1Fujian Shengdi Pharmaceutical Co., Ltd.NCT06723691Written as Warfarin
- A Drug-Drug Interaction Study Between XW003 and Metformin, Warfarin, Rosuvastatin or DigoxinCompletedPhase 1Hangzhou Sciwind Biosciences Co., Ltd.NCT06335134Written as Warfarin
- A Study of Enlicitide Decanoate (MK-0616), Warfarin, and Lisinopril in Healthy Adult Participants (MK-0616-026)CompletedPhase 1Merck Sharp & Dohme LLCNCT06772779Written as Warfarin
- A Study of Mirikizumab in Participants With Plaque PsoriasisCompletedPhase 1Eli Lilly and CompanyNCT03718884Written as Drug Cocktail
- A Study to Evaluate the Safety of a Single Intravenous (IV) Dose of Orbactiv (Oritavancin) in Participants on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI)CompletedPhase 4The Medicines CompanyNCT02452918Written as Warfarin
- A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese SubjectsCompletedPhase 1Innovent Biologics (Suzhou) Co. Ltd.NCT05815680Written as warfarin
- A Study in Healthy People to Test Whether BI 730357 Influences the Amount of Caffeine, Warfarin, Omeprazole, and Midazolam in the BloodCompletedPhase 1Boehringer IngelheimNCT04679948Written as Coumadin®
Showing 20 of 68.
As the comparator · 100 — what is tested is compared with Warfarin
- SWITCH: Apixaban vs Vitamin K in HM3RecruitingPhase 3Columbia UniversityNCT07471139Written as Warfarin
- Apixaban Versus Warfarin for Left Ventricular ThrombusRecruitingPhase 3University of ArizonaNCT07709780Written as Warfarin
- Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki DiseaseRecruitingPhase 4Children's Hospital of Fudan UniversityNCT05643651Written as Warfarin
- STudy of Aspirin Removal in Patients Supported by the Fully Magnetically Levitated CH-VAD PumpNot yet recruitingPhase 4China National Center for Cardiovascular DiseasesNCT07644247Written as Warfarin (INR 2-3) with aspirin
- Rivaroxaban vs Warfarin in Patients With Mechanical Heart ValvesEnrolling by invitationPhase 3Rawalpindi Institute of CardiologyNCT07456085Written as Warfarin
- Rivaroxaban in Idiopathic Membranous NephropathyRecruitingPhase 4Beijing Friendship HospitalNCT07404436Written as Warfarin Sodium
- Treatment With Apixaban Versus Warfarin in Patients With Left Ventricular Thrombus After Acute Myocardial InfarctionRecruitingPhase 4Karolinska InstitutetNCT06515730Written as Warfarin
- Anticoagulation in Post MI LV Thrombus Trial in NepalRecruitingPhase 4Shahid Gangalal National Heart CentreNCT05794399Written as Warfarin
- Safety and Effectiveness of Early Aspirin Administration After Mitral Valve RepairRecruitingPhase 4Guangdong Provincial People's HospitalNCT06738992Written as Warfarin
- Rivaroxaban and Vitamin K Antagonists for the Anticoagulation for the Implantation of Vena Cava FiltersRecruitingPhase 3Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT04066764Written as Warfarin
- Rivaroxaban for the Prevention of Deep Vein Thrombosis in Patients With Left Iliac Vein Compression - The PLICTS StudyRecruitingPhase 3Second Affiliated Hospital, School of Medicine, Zhejiang UniversityNCT04067505Written as Warfarin
- Safety and Efficacy of Rivaroxaban and Apixaban in Comparison to Warfarin in Left Ventricular Clot- Clinical TrialRecruitingPhase 4Peshawar Institute of CardiologyNCT05973188Written as Warfarin
- Efficacy and Safety of Edoxaban in Patients With Atrial Fibrillation and Mitral StenosisRecruitingPhase 2Sung-Hwan KimNCT05540587Written as Warfarin
- Comparison of Clopidogrel-based Antiplatelet Therapy Versus Warfarin as Secondary Prevention Strategy for AntiPhospholipid Syndrome-related STROKEActive, not recruitingPhase 4Seoul National University HospitalNCT05995600Written as Warfarin
- RIvaroxaban for Stroke Patients With AntiPhospholipid SyndromeCompletedPhase 2University College, LondonNCT03684564Written as Warfarin
- Rivaroxaban vs. Warfarin for Post Cardiac Surgery Atrial FibrillationCompletedPhase 3Massachusetts General HospitalNCT03702582Written as Warfarin
- Impact of Anticoagulation Therapy on the Cognitive Decline and Dementia in Patients With Non-Valvular Atrial FibrillationCompletedPhase 4Intermountain Health Care, Inc.NCT03061006Written as Warfarin
- Dabigatran for Mitral Stenosis Atrial FibrillationActive, not recruitingPhase 4The University of Hong KongNCT04045093Written as Warfarin
- Left Atrial Appendage CLOSURE in Patients With Atrial Fibrillation Compared to Medical TherapyCompletedPhase 4Charite University, Berlin, GermanyNCT03463317Written as Warfarin
- Can the Lambre Device Occlude IRRegular And Large Appendages in Patients With Non-Valvular AFWithdrawnNot applicableBrian O'Neill MDNCT04684212Written as Market approved oral anticoagulation (OAC), such as warfarin (Coumadin), dabigatran (Pradaxa), rivaroxaban (Xarelto), apixiban (Eliquis), edoxaban (Savaysa), or betrixaban (Bevyxxa)
Showing 20 of 100.
Codes
What other systems call Warfarin · ClinicalTrials.gg INT008420
- MeSH (NLM) D014859WarfarinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 5Q7ZVV76EIWARFARINConfirmed FDA, NLM, Wikidata
- RxNorm 11289Confirmed FDA, Wikidata
- Wikidata Q113368879rac-warfarinConfirmed FDA, NLM, Wikidata
- Wikidata Q407431(RS)-warfarinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C945WarfarinOne source FDA
- DrugBank DB00682One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D014859 | Warfarin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 5Q7ZVV76EI | WARFARIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 11289 | — | Confirmed FDA, Wikidata |
| Wikidata | Q113368879 | rac-warfarin | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q407431 | (RS)-warfarin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C945 | Warfarin | One source FDA |
| DrugBank | DB00682 | — | One source Wikidata |
Also registered as warfarin potassium (UNII I47IU4FOCO · RxNorm 82118) and warfarin sodium (UNII 6153CWM0CL · RxNorm 114194).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.