Tofacitinib: all 184 studies that test it

Page 1 of 2. Open to participants first (41), then studies with results posted, then the rest; newest registration first within each.

• A Study to Evaluate the Safety and Pharmacokinetics of Multiple Doses Upadacitinib, Tofacitinib, and Baricitinib in Healthy Adult VolunteersRecruitingNCT07843693Phase 1
• Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1RecruitingNCT07598643Phase 2
• Comparison of Methotrexate and Tofacitinib in Chronic Plaque PsoriasisNot yet recruitingNCT07581418Not applicable
• Major Adverse Cardiovascular Events (MACE) in Rheumatoid Arthritis Patient With Moderate to Severe Disease Activity Treated With Tofacitinib and Statins vs TNF Inhibitors: TOFSTAT CLINICAL TRIALRecruitingNCT07554820Phase 4
• Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye DiseaseRecruitingNCT07547930Phase 2
• Tofacitinib Plus Imatinib in Moderate-to-Severe Palmoplantar PustulosisNot yet recruitingNCT07530367Phase 3
• A Precision Medicine Trial for Patients With Relapsed or Refractory T Cell ALLNot yet recruitingNCT07522801Phase 2
• Tofacitinib vs Methotrexate for Severe Alopecia Areata (TOFA-MTX-AA)Not yet recruitingNCT07406204Phase 4
• Utilization of a Microdevice for Psoriasis and Atopic DermatitisNot yet recruitingNCT07352566Phase 4
• The Efficacy and Safety of Anti-inflammation Treatment (Hirudoid Introduction Followed by Yellow Light Therapy) Combined With Tofacitinib and Doxycycline in Chinese Adult Patients With Mild to Moderate Erythematous Telangiectatic RosaceaRecruitingNCT07343635Not applicable
• Combination Therapy With Infliximab and Tofacitinib for Acute Severe Ulcerative Colitis - CINTO TrialNot yet recruitingNCT07297069Phase 2
• Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren DiseaseRecruitingNCT07281456Phase 2
• Comparison Between Oral Methotrexate and Tofacitinib in Chronic Plaque PsoriasisRecruitingNCT07261306Early Phase 1
• Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder ArthroplastyRecruitingNCT07138898Phase 2
• Evaluation of Efficacy and Safety of add-on Tofacitinib in Patients With Oral Lichen PlanusRecruitingNCT07131813Phase 4
• A Phase 2 Trial to Assess Safety and Efficacy of Tofacitinib 2% Cream in the Treatment of Cutaneous T-cell Lymphoma (CTCL), Stages IA, IB, and IIARecruitingNCT06698822Phase 2
• Tofacitinib in Patients With Amyotrophic Lateral SclerosisNot yet recruitingNCT06689982Early Phase 1
• JAK Inhibitor Dose TAPering Strategy StudyRecruitingNCT06687551Phase 4
• Trial of Sequential Medications AfteR TNFi Failure in Juvenile Idiopathic ArthritisRecruitingNCT06654882Phase 3
• TOFACITINIB vs TOFACITINIB WITH MESALAMINE IN ULCERATIVE COLITISNot yet recruitingNCT06625450Phase 4
• A Randomized, Controlled, Open-label, Multicenter Clinical Trial Comparing the Efficacy and Safety of a Precision Treatment Regimen Based on Clinical-molecular Phenotypes with a Conventional Treatment Regimen in the Treatment of Patients with Active Takayasu's ArteritisRecruitingNCT06498089Phase 4
• Efficacy and Safety of Dupilumab in Combination With Tofacitinib in Moderate to Severe Adult AD PatientsNot yet recruitingNCT06465732Phase 4
• 3T Therapy in the Treatment of MDA5-positive DermatomyositisEnrolling by invitationNCT06438679Phase 4
• The Efficacy and Safety of Tofacitinib in Patients With Glucocorticoid Resistant ICIs-related MyocarditisNot yet recruitingNCT06393972Phase 2
• Efficacy and Safety of Tofacitinib in Patients With Prurigo NodularisNot yet recruitingNCT06201715Not applicable
• Evaluation of the Efficacy and Safety of Methylprednisolone Combined With the JAK Inhibitors in the Treatment of Toxic Epidermal NecrolysisRecruitingNCT06119490Early Phase 1
• ToFAcitinib in Early Active Axial SpondyloarThritis:RecruitingNCT06112665Phase 4
• A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)RecruitingNCT06095128Phase 4
• Effectiveness of Tofacitinib in Systemic SclerosisRecruitingNCT06044844Phase 2
• Tofacitinib Associated With Meglumine Antimoniate in Cutaneous LeishmaniasisNot yet recruitingNCT06011343Phase 2/3
• Tocilizumab and Tofacitinib in the Treatment of Vascular Behçet's SyndromeRecruitingNCT05845723Phase 2
• Comparison of Tofacitinib and Prednisolone in the Treatment of Active Takayasu's ArteritisRecruitingNCT05749666Phase 3
• Novel Targeted Drugs Combined With R-ICE Regimen in Relapsed and Refractory Diffuse Large B-cell LymphomaRecruitingNCT05348213Phase 2
• Stand UP to Rheumatoid Arthritis (SUPRA)RecruitingNCT05305066Not applicable
• Tofacitinib Versus Cyclosporine for Steroid Refractory Acute Severe Ulcerative ColitisNot yet recruitingNCT05112263Not applicable
• Comparison of Tofacitinib and Methotrexate in Takayasu's ArteritisRecruitingNCT05102448Phase 4
• Study of Salvage Therapy to Treat Patients With Granulomatosis With PolyangiitisRecruitingNCT04871191Phase 3
• Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic ArthritisRecruitingNCT04610476Phase 3
• Advanced Therapeutics in Rheumatoid Arthritis (RA)RecruitingNCT03976245Phase 4
• Examination of Efficacy and Safety of Baricitinib in RA PatientsRecruitingNCT03755466Phase 2
• Treatment of Rheumatoid Arthritis With DMARDs: Predictors of ResponseRecruitingNCT03414502Phase 3
• Study To Evaluate The Efficacy Of Tofacitinib In Patients With SJS/TENCompletedNCT06474078Not applicableResults posted
• Effectiveness and Safety of Tofacitinib in Patients With Recalcitrant Frontal Fibrosing Alopecia : A Pilot StudyCompletedNCT06202560Not applicableResults posted
• Evaluation of Tofacitinib in Prevention of Photosensitivity in LupusCompletedNCT05048238Phase 1Results posted
• Tofacitinib For Treatment Of Chronic PouchitisTerminatedNCT04580277Phase 2Results posted
• Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's SyndromeActive, not recruitingNCT04496960Phase 1/2Results posted
• Tofacitinib for Treatment of Moderate COVID-19TerminatedNCT04415151Phase 2Results posted
• TO ASSESS THE EFFICACY AND SAFETY OF PF-06650833, PF-06651600, AND TOFACITINIB ALONE AND IN COMBINATION IN PARTICIPANTS WITH ACTIVE RHEUMATOID ARTHRITIS WITH AN INADEQUATE RESPONSE TO METHOTREXATECompletedNCT04413617Phase 2Results posted
• Tofacitinib for Immune Skin Conditions in Down SyndromeCompletedNCT04246372Phase 2Results posted
• Effectiveness and Safety of Tofacitinib in Patients With Extensive and Recalcitrant Alopecia AreataCompletedNCT03800979Phase 4Results posted
• Tofacitinib Hypothesis-generating, Pilot Study for Corticosteroid-Dependent SarcoidosisCompletedNCT03793439Phase 1Results posted
• Tofacitinib for Inflammatory Eye DiseaseStatus unknownNCT03580343Phase 2Results posted
• Efficacy and Safety of Tofacitinib in Subjects With Active Ankylosing Spondylitis (AS)CompletedNCT03502616Phase 3Results posted
• Efficacy And Safety Of Tofacitinib In Chinese Subjects With Active Psoriatic ArthritisCompletedNCT03486457Phase 3Results posted
• Open-label Study of Tofacitinib for Moderate to Severe Skin Involvement in Young Adults With LupusCompletedNCT03288324Phase 1/2Results posted
• A Study of Tofacitinib in Patients With Ulcerative Colitis in Stable RemissionTerminatedNCT03281304Phase 4Results posted
• Evaluation of Tofacitinib in Early Diffuse Cutaneous Systemic Sclerosis (dcSSc)CompletedNCT03274076Phase 1/2Results posted
• A Safety, Efficacy And Pharmacokinetics Study Of Tofacitinib In Pediatric Patients With sJIACompletedNCT03000439Phase 3Results posted
• Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid ArthritisCompletedNCT02831855Phase 4Results posted
• Topical Tofacitinib for the Treatment of Alopecia Areata and Its VariantsCompletedNCT02812342Phase 2Results posted
• Efficacy Study Of Tofacitinib In Pediatric JIA PopulationCompletedNCT02592434Phase 3Results posted
• Musculoskeletal Ultrasound Assessment of Therapeutic Response of Tofacitinib in Rheumatoid Arthritis PatientsCompletedNCT02321930Phase 4Results posted
• Tofacitinib for the Treatment of Alopecia Areata and Its VariantsCompletedNCT02312882Not applicableResults posted
• Study To Evaluate The Efficacy Of Tofacitinib In Moderate To Severe Alopecia Areata, Totalis And UniversalisCompletedNCT02299297Phase 2Results posted
• A Study To Evaluate The Safety And Efficacy Of Tofacitinib Modified Release Tablets Compared To Tofacitinib Immediate Release Tablets In Adult Patients With Rheumatoid ArthritisCompletedNCT02281552Phase 3Results posted
• An Efficacy And Safety Study Evaluating Tofacitinib With And Without Methotrexate Compared To Adalimumab With MethotrexateCompletedNCT02187055Phase 4Results posted
• A Study to Assess Immune Response Following Zoster Vaccination to Subjects With Rheumatoid Arthritis Receiving Tofacitinib or Placebo With Background MethotrexateCompletedNCT02147587Phase 2Results posted
• Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid ArthritisCompletedNCT02092467Phase 4Results posted
• Tofacitinib Ointment For Atopic Dermatitis (Atopic Eczema)CompletedNCT02001181Phase 2Results posted
• Open-Label Extension Study Of Tofacitinib In Psoriatic ArthritisCompletedNCT01976364Phase 3Results posted
• Tofacitinib In Psoriatic Arthritis Subjects With Inadequate Response to TNF InhibitorsCompletedNCT01882439Phase 3Results posted
• Efficacy And Safety Of Tofacitinib In Psoriatic Arthritis: Comparator StudyCompletedNCT01877668Phase 3Results posted
• Tofacitinib Ointment For Chronic Plaque PsoriasisCompletedNCT01831466Phase 2Results posted
• A Study Evaluating The Efficacy And Safety Of CP-690,550 In Asian Subjects With Moderate To Severe Plaque PsoriasisCompletedNCT01815424Phase 3Results posted
• Dose-Ranging Study Of Tofacitinib In Adults With Active Ankylosing SpondylitisCompletedNCT01786668Phase 2Results posted
• Co-Administration Of Methotrexate And CP-690,550CompletedNCT01745055Phase 1Results posted
• CP-690,550 Thorough QTc StudyCompletedNCT01743677Phase 1Results posted
• Pharmacokinetics Of CP-690,550 In Patients With Impaired Renal FunctionCompletedNCT01740362Phase 1Results posted
• Multiple Dose Escalation Study In Medically Stable Subjects With PsoriasisCompletedNCT01736696Phase 1Results posted
• Study Of The Mechanism Of Action Of CP-690,550 In The Skin Of Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01710046Phase 2Results posted
• A Study Of CP-690,550 In Stable Kidney Transplant PatientsCompletedNCT01710033Phase 1Results posted
• Pharmacokinetics And Dialysability Of CP-690,550 In Subjects With End-Stage Renal DiseaseCompletedNCT01710020Phase 1Results posted
• A Long Term Study To Evaluate The Safety, Tolerability And Efficacy Of CP-690,550 In Patients With Moderate To Severe Plaque Psoriasis And/Or Psoriatic ArthritisCompletedNCT01519089Phase 3Results posted
• Pharmacokinetics Of CP-690,550 In Pediatric Patients With Juvenile Idiopathic Arthritis (JIA)CompletedNCT01513902Phase 1Results posted
• Long-Term Safety Study Of Tofacitinib In Patients With Juvenile Idiopathic ArthritisCompletedNCT01500551Phase 2/3Results posted
• Long-Term Study Of CP-690,550 In Subjects With Ulcerative ColitisCompletedNCT01470612Phase 3Results posted
• A Open-Label Study Of CP-690,550 As Long-Term Therapy (48 Weeks) In Subjects With Crohn's DiseaseCompletedNCT01470599Phase 2Results posted
• A Study Evaluating The Efficacy And Safety Of CP-690,550 In Patients With Moderate To Severe Ulcerative ColitisCompletedNCT01465763Phase 3Results posted
• A Study To Evaluate Both The Efficacy and Safety Profile of CP-690,550 In Patients With Moderately to Severely Active Ulcerative ColitisCompletedNCT01458951Phase 3Results posted
• A Study Of Oral CP-690,550 As A Maintenance Therapy For Ulcerative ColitisCompletedNCT01458574Phase 3Results posted
• The Safety And Efficacy Of Maintenance Therapy With CP-690,550CompletedNCT01393899Phase 2Results posted
• A Study To Investigate Safety And Efficacy Of CP-690,550 For Induction Therapy In Subjects With Moderate To Severe Crohn's DiseaseCompletedNCT01393626Phase 2Results posted
• A Study To Assess the Immune Response Following Administration Of Influenza and Pneumococcal Vaccines To Subjects With Rheumatoid Arthritis Receiving CP-690,550 Or PlaceboCompletedNCT01359150Phase 2Results posted
• A One-Year Study To Evaluate The Efficacy And Safety Of CP-690,550 For Patients With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01309737Phase 3Results posted
• A One-Year Study To Evaluate The Effects And Safety Of CP-690,550 In Patients With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01276639Phase 3Results posted
• Effects Of CP-690,550 (Tasocitinib) On Cholesterol Metabolism In Patients With Active Rheumatoid ArthritisCompletedNCT01262118Phase 1Results posted
• CP-690-550 Ointment For Chronic Plaque PsoriasisCompletedNCT01246583Phase 2Results posted
• A Phase 3, Multi Site, Randomized, Double Blind, Placebo Controlled Study Of The Efficacy And Safety Comparing CP- 690,550 And Etanercept In Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01241591Phase 3Results posted
• A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01186744Phase 3Results posted
• Effects of Tofacitinib (CP-690,550) on Magnetic Resonance Imaging (MRI)- Assessed Joint Structure In Early Rheumatoid Arthritis (RA)CompletedNCT01164579Phase 2Results posted

← Tofacitinib overview