Drug
Thymoglobulin clinical trials
Also written Rabbit antithymocyte globulin and ATG Fresenius.
- studies test it
- 116
- open now
- 11
- in phase 3
- 19
- first study started
- 2000
Keep track of what changes. Save the thymoglobulin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Development codes
Other names
Studies by the year they started
116 studies that test it; most in 2006 (11)
| Year | Studies |
|---|---|
| 2000 | 1 |
| 2001 | 2 |
| 2002 | 3 |
| 2003 | 4 |
| 2004 | 1 |
| 2005 | 6 |
| 2006 | 11 |
| 2007 | 8 |
| 2008 | 8 |
| 2009 | 9 |
| 2010 | 9 |
| 2011 | 1 |
| 2012 | 3 |
| 2013 | 4 |
| 2014 | 5 |
| 2015 | 4 |
| 2016 | 6 |
| 2017 | 5 |
| 2018 | 6 |
| 2019 | 4 |
| 2020 | 6 |
| 2021 | 2 |
| 2022 | 2 |
| 2023 | 4 |
| 2024 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 17
- Phase 2
- 64
- Phase 3
- 19
- Phase 4
- 20
- No phase
- 11
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 109
M.D. Anderson Cancer Center (12) · Northwestern University (4) · The Korean Society of Pediatric Hematology Oncology (4) · Columbia University (3) · University of Miami (3) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (3) · St. Jude Children's Research Hospital (3) · Washington University School of Medicine (3)
Often tested with
Tested in the same studies.
Fludarabine (34) · Cyclophosphamide (29) · Mycophenolic Acid (18) · Tacrolimus (17) · Busulfan (14) · Rituximab (11) · Filgrastim (11) · Mesna (10)
Studies
Open first, then newest update. How each study uses thymoglobulin is read from its arms, and is right about nine times in ten.
Testing it · 116
- Haploidentical HCT for Severe Aplastic AnemiaRecruitingPhase 2St. Jude Children's Research HospitalNCT04558736Written as Anti-Thymocyte Globulin (Rabbit)
- Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic LeukaemiaRecruitingPhase 2/3St. Anna KinderkrebsforschungNCT01949129Written as Grafalon
- CD45RA-depleted CD19-CAR T Cell Consolidation After TCRαβ+/CD19 B Cell-depleted Haploidentical Hematopoietic Cell Transplantation for Relapsed/Refractory CD19+ ALL and LymphomaRecruitingPhase 1St. Jude Children's Research HospitalNCT07257419Written as Anti-Thymocyte Globulin (Rabbit)
- Autologous Stem Cell Transplant for Crohn's DiseaseRecruitingPhase 2Aaron EtraNCT03219359Written as Thymoglobulin
- A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT)RecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT05736419Written as Rabbit ATG
- Phase III Study Comparing GVHD Prophylaxis With ATG-thymoglobulin to ATLG-grafalon in Elderly Patients With Acute Myeloid Leukemia or Myelodysplasic Syndrome and Receiving an Allogeneic Hematopoietic Stem Cell Transplantation With a 10/10 HLA Matched Unrelated DonorRecruitingPhase 3Assistance Publique - Hôpitaux de ParisNCT06083129Written as Grafalon
- MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme MalignanciesRecruitingPhase 2Masonic Cancer Center, University of MinnesotaNCT05735717Written as Thymoglobulin
- Stem Cell Transplantation in Crohn's DiseaseRecruitingPhase 1/2Cedars-Sinai Medical CenterNCT04224558Written as anti-thymocyte globulin (rabbit)
- The Effect and Safety Profile of Thymoglobulin® in Primary Cardiac Transplant RecipientsEnrolling by invitationPhase 2Cedars-Sinai Medical CenterNCT03292861Written as Thymoglobulin
- PROPHYLAXIS OF GVH IN ELDERLY PATIENTS RECEIVING HAPLOIDENTICAL ALLOGENIC HEMATOPOIETIC STEM CELL TRASNPLANTATION USE OF A LOW DOSE ANTI-LYMPHOCYTIC SERUMNot yet recruitingPhase 2Institut Paoli-CalmettesNCT06066255Written as Thymoglobulin Injectable Product
- Allogeneic Hematopoietic Cell Transplantation From HLA-matched Donor After Flu-Mel-PTCy Versus Flu-Mel-ATG Reduced-intensity ConditioningRecruitingPhase 2University of LiegeNCT03852407Written as Thymoglobulin
- A Trial Comparing Unrelated Donor BMT With IST for Pediatric and Young Adult Patients With Severe Aplastic Anemia (TransIT, BMT CTN 2202)TerminatedPhase 3Boston Children's HospitalNCT05600426Written as rabbit anti-thymocyte globulin (ATG)
- Open-Label Phase 2 Trial of a Steroid-Free, CNI-Free, Belatacept-Based Immunosuppressive RegimenTerminatedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT01856257Written as Anti-thymocyte Globulin (Rabbit)
- Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney TransplantationTerminatedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT01517984Written as Tacrolimus (CNI) Withdrawal
- Treatment of Early Borderline Lesions in Low Immunological Risk Kidney Transplant Patients (TRAINING)Active, not recruitingPhase 4Fundación Canaria Instituto de Investigación Sanitaria de CanariasNCT04936282Written as Grafalon
- Targeting the IPA and Matching for the Non-Inherited Maternal Antigen for Haplo-Cord TransplantationCompletedPhase 2Weill Medical College of Cornell UniversityNCT01810588Written as anti-thymocyte globulin (rabbit)
- Belatacept Early Steroid Withdrawal TrialCompletedPhase 4University of CincinnatiNCT01729494Written as rabbit antithymocyte globulin
- Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)CompletedPhase 2Medical College of WisconsinNCT03263559Written as Rabbit-ATG
- Rabbit Antithymocyte Globulin (Thymoglobuline) With Ciclosporin for Patients With Acquired Aplastic AnaemiaCompletedPhase 2European Society for Blood and Marrow TransplantationNCT00471848Written as rabbit antithymocyte globulin
- A Study Comparing Haploidentical Hematopoietic Stem Cell Transplantations (HSCTs) From Young Non-first-degree and Older First-degree Donors in Hematological MalignanciesActive, not recruitingPhase 3First Affiliated Hospital of Zhejiang UniversityNCT04547049Written as Rabbit antithymocyte globulin
See all 116 studies that test thymoglobulin →
Given in every arm · 66 — thymoglobulin is usual care beside what is tested
- Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic AnemiaRecruitingPhase 2Northside Hospital, Inc.NCT02828592Written as Rabbit ATG
- A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney TransplantationRecruitingPhase 2/3SanofiNCT07412470Written as rabbit anti-thymocyte globulin
- Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Thiotepa in Treating Patients With Non-malignant DisordersRecruitingPhase 2Fred Hutchinson Cancer CenterNCT03980769Written as Rabbit Anti-Thymocyte Globulin
- Total Body Irradiation and Astatine-211-Labeled BC8-B10 Monoclonal Antibody for the Treatment of Nonmalignant DiseasesRecruitingPhase 1/2Fred Hutchinson Cancer CenterNCT04083183Written as Lapine T-Lymphocyte Immune Globulin
- Allo HSCT for High Risk HemoglobinopathiesRecruitingPhase 2Masonic Cancer Center, University of MinnesotaNCT06872333Written as Thymoglobulin
- MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure.RecruitingPhase 2Masonic Cancer Center, University of MinnesotaNCT06412497Written as Rabbit ATG
- TCRαβ-depleted Progenitor Cell Graft With Early Memory T-cell DLI, Plus Selected Use of Blinatumomab, in naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic MalignanciesRecruitingPhase 1St. Jude Children's Research HospitalNCT07052370Written as Thymoglobulin
- HSCT for Patients With Fanconi Anemia Using Risk-Adjusted ChemotherapyRecruitingPhase 2Children's Hospital Medical Center, CincinnatiNCT02143830Written as rabbit ATG
- Effects of Inhibiting Early Inflammation in Kidney Transplant PatientsCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT02495077Written as Thymoglobulin®
- Optimization of NULOJIX® Usage Towards Minimizing CNI Exposure in Simultaneous Pancreas and Kidney TransplantationTerminatedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT01790594Written as Anti-thymocyte Globulin (Rabbit)
- Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic SyndromeActive, not recruitingPhase 3Children's Oncology GroupNCT05457556Written as Lapine T-Lymphocyte Immune Globulin
- Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)CompletedPhase 2Fred Hutchinson Cancer CenterNCT04965597Written as Lapine T-Lymphocyte Immune Globulin
- A Blood Stem Cell Transplant for Sickle Cell DiseaseActive, not recruitingPhase 1City of Hope Medical CenterNCT03249831Written as Rabbit anti-thymocyte globulin
- Tocilizumab for the Prevention of Graft Failure and GVHD in Haplo-Cord TransplantationActive, not recruitingPhase 2Weill Medical College of Cornell UniversityNCT04395222Written as Anti-thymocyte globulin (rabbit)
- Romidepsin Maintenance After Allogeneic Stem Cell TransplantationCompletedPhase 1Ohio State University Comprehensive Cancer CenterNCT02512497Written as Thymoglobulin
- Provision of TCRγδ T Cells and Memory T Cells Plus Selected Use of Blinatumomab in Naïve T-cell Depleted Haploidentical Donor Hematopoietic Cell Transplantation for Hematologic Malignancies Relapsed or Refractory Despite Prior TransplantationActive, not recruitingPhase 2St. Jude Children's Research HospitalNCT02790515Written as Anti-thymocyte globulin (rabbit)
- ATG Plus PTCy vs ATG for CGVHD ProphylaxisActive, not recruitingPhase 2McMaster UniversityNCT04202835Written as Anti-Thymocyte globulin (rabbit)
- CsA+ATG+AVA vs. CsA+AVA for the Treatment of Newly-diagnosed SAA in the ElderlyCompletedPhase 4Peking Union Medical College HospitalNCT05996393Written as Anti-Human Thymocyte Immunoglobulin, Rabbit
- A Study to Evaluate the Safety and Efficacy of Dual Costimulation Blockade With VIB4920 and Belatacept for Prophylaxis of Allograft Rejection in Adults Receiving a Kidney TransplantCompletedPhase 2AmgenNCT04046549Written as Thymoglobulin
- MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCsCompletedPhase 2Masonic Cancer Center, University of MinnesotaNCT02582775Written as Thymoglobulin
Showing 20 of 66.
As the comparator · 8 — what is tested is compared with thymoglobulin
- A Study Comparing Siplizumab With Rabbit Anti-Thymocyte Globulin to Help the Body Accept a Kidney TransplantRecruitingPhase 2Nefro Avillion Clinical Development, LLCNCT07508787Written as Rabbit anti-thymocyte globulin
- Methods of T Cell Depletion Trial (MoTD)RecruitingPhase 2University of BirminghamNCT04888741Written as Thymoglobulin
- Haplocompatible Transplant Using TCRα/β Depletion Followed by CD45RA-Depleted Donor Lymphocyte Infusions for Severe Combined Immunodeficiency (SCID)Active, not recruitingPhase 1/2St. Jude Children's Research HospitalNCT03597594Written as Anti-thymocyte globulin (rabbit)
- Simulect Versus ATG in Sensitized Renal Transplant PatientCompletedPhase 4University Hospital, ToulouseNCT02377193Written as ATG Fresenius
- Randomized Trial for Mixed Acute RejectionCompletedPhase 2University of CincinnatiNCT00771875Written as Rabbit Antithymocyte Globulin (RATG)
- Lupus Immunosuppressive/Immunomodulatory Therapy or Stem Cell Transplant (LIST)WithdrawnPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00230035Written as Rabbit anti-thymocyte globulin
- Simultaneous Pancreas-kidney Transplantation With Campath ProtocolCompletedPhase 3Dr. Claudia BösmüllerNCT00316810Written as Rabbit Anti-Human Thymocyte Globulin
- Safety/Efficacy of Induction Agents With Tacrolimus, MMF, and Rapid Steroid Withdrawal in Renal Transplant RecipientsCompletedPhase 4Astellas Pharma IncNCT00113269Written as rabbit anti-thymocyte globulin
Codes
What other systems call thymoglobulin · ClinicalTrials.gg INT004955
- MeSH (NLM) C512542thymoglobulinConfirmed ClinicalTrials.gov, NLM
- UNII (FDA) D7RD81HE4WLAPINE T-LYMPHOCYTE IMMUNE GLOBULINConfirmed FDA, NLM
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C512542 | thymoglobulin | Confirmed ClinicalTrials.gov, NLM |
| UNII (FDA) | D7RD81HE4W | LAPINE T-LYMPHOCYTE IMMUNE GLOBULIN | Confirmed FDA, NLM |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.