DrugBiological
Thrombin clinical trials
Includes 12 studies of Thrombin.
- studies test it
- 15
- open now
- 1
- in phase 3
- 7
- first study started
- 2004
Keep track of what changes. Save the Thrombin studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Studies by the year they started
15 studies that test it; most in 2010 (3)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2008 | 1 |
| 2009 | 1 |
| 2010 | 3 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 1 |
| 2014 | 2 |
| 2015 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 2
- 3
- Phase 3
- 7
- Phase 4
- 3
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 7 · Other 8
Ethicon, Inc. (6) · Medical University of South Carolina (1) · Instituto Grifols, S.A. (1) · Hospital for Special Surgery, New York (1) · University of Milan (1) · NYU Langone Health (1) · University of Kansas Medical Center (1) · National Science Council, Taiwan (1)
Often tested with
Tested in the same studies.
Fibrinogen (10) · Tranexamic Acid (1) · Aminocaproic Acid (1)
Studies
Open first, then newest update. How each study uses Thrombin is read from its arms, and is right about nine times in ten.
Testing it · 15
- Postoperative Non-Opioid Pain Management Utilizing Local Anesthetics Coupled With Modulated CoagulationNot yet recruitingPhase 4NYU Langone HealthNCT07644923Written as Thrombin
- The Paediatric EVICEL® Neuro StudyTerminatedPhase 3Ethicon, Inc.NCT02309645Written as EVICEL® Fibrin Sealant
- The Paediatric EVICEL® Soft Tissue and Parenchymal Organ Bleeding StudyCompletedPhase 3Ethicon, Inc.NCT02227706Written as EVICEL® Fibrin Sealant
- A Trial Comparing Wound Drainage and Post-operative Complications With and Without the Use of EVICEL™ Fibrin Sealant in ThyroidectomyCompletedNot applicableMedical University of South CarolinaNCT01226914Written as EVICEL
- The EVICEL® Neurosurgery Phase III StudyCompletedPhase 3Ethicon, Inc.NCT02457546Written as EVICEL Fibrin Sealant
- The Combined Efficacy of Evicel and Tranexamic Acid on Total Knee ArthroplastyWithdrawnPhase 3Montefiore Medical CenterNCT02553122Written as Evicel
- Safety and Efficacy of Topical Thrombin (Human) Grifols as an Adjunct to Hemostasis During SurgeryCompletedPhase 2Instituto Grifols, S.A.NCT02014402Written as Human thrombin
- Trial Comparing Outcomes With Merocel Packing or Thrombin-JMI for Anterior EpistaxisTerminatedNot applicableUniversity of Kansas Medical CenterNCT00814333Written as Thrombin-JMI
- The EVICEL® Gastrointestinal StudyCompletedPhase 2Ethicon, Inc.NCT01589822Written as EVICEL Fibrin Sealant
- The Use of Evicel to Reduce Blood Loss in Total Knee Replacement SurgeryCompletedPhase 4Hospital for Special Surgery, New YorkNCT01235715Written as Evicel fibrin sealant
- The Use of Fibrin Sealant to Reduce Bleeding After Total Knee ReplacementCompletedNot applicableUniversity of MilanNCT01816282Written as Evicel
- A Prospective, Randomized Trial of Histoacryl Injection Versus Thrombin in the Control of Acute Gastric Variceal BleedingStatus unknownPhase 3National Science Council, TaiwanNCT01717612Written as Thrombin
- A Study to Evaluate the Safety and Effectiveness of EVICEL as an Adjunct to Sutured Dural RepairCompletedPhase 2/3Ethicon, Inc.NCT01174992Written as Evicel
- Evicel Study on the Peri-operative Bleeding in Total Knee Prothesis SurgeryStatus unknownPhase 4Clinique Mutualiste Chirurgicale de la LoireNCT00983112Written as Human Fibrinogen and human thrombin (Evicel)
- A Study to Compare Human Thrombin Against Bovine Thrombin in Its Ability to Stop Bleeding After SurgeryCompletedPhase 3Ethicon, Inc.NCT00196534Written as Human Thrombin
As the comparator · 3 — what is tested is compared with Thrombin
- Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin GraftRecruitingPhase 4University of Kansas Medical CenterNCT06379724Written as Thrombin JMI
- A Study of Safety and Efficacy of Fibrin Sealant Grifols as an Adjunct to Haemostasis During Surgery in Paediatric ParticipantsCompletedPhase 3Instituto Grifols, S.A.NCT03461406Written as EVICEL
- Study of Recombinant Human Thrombin for Bleeding During SurgeryCompletedPhase 3ZymoGeneticsNCT00245336Written as bovine thrombin
Codes
What other systems call Thrombin · ClinicalTrials.gg INT008315
- MeSH (NLM) D013917ThrombinConfirmed ClinicalTrials.gov, Wikidata
- UNII (FDA) 25ADE2236LTHROMBINConfirmed FDA, Wikidata
- RxNorm 10528One source FDA
- Wikidata Q409166Coagulation factor II, thrombinConfirmed FDA, Wikidata
- NCI Thesaurus C87773ThrombinOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D013917 | Thrombin | Confirmed ClinicalTrials.gov, Wikidata |
| UNII (FDA) | 25ADE2236L | THROMBIN | Confirmed FDA, Wikidata |
| RxNorm | 10528 | — | One source FDA |
| Wikidata | Q409166 | Coagulation factor II, thrombin | Confirmed FDA, Wikidata |
| NCI Thesaurus | C87773 | Thrombin | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.