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Dental Caries clinical trials

The registry lists 1,171 studies for Dental Caries across more than 10 countries. 209 are recruiting or about to start. 1,028 of them are mainly about Dental Caries (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10. Counting its narrower condition Root Caries too: 1,204 studies, 218 open.

ClinicalTrials.gov finds 1,423 studies for Dental Caries. How that becomes 1,168 here

This page counts the studies the registry files under Dental Caries, and those it files under no condition that list Dental Cariesthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 1,423Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −33Filed under a narrower condition, counted on its own pageRoot Caries 33
  3. −36List Dental Caries as a condition, but the registry did not file them under itMost often written as “Dental Caries in Children” (19), “Dental Caries Extending to Pulp” (3), and “Dental Caries on Pit and Fissure Surface” (2). The registry filed them under other conditions only, most often Stomatognathic Diseases (4) and Van der Woude syndrome (3).
  4. −187Match it another way61 name it in the title, 5 in a keyword, and 121 by a synonym or other text the search reads.
  5. 1,167Counted here and found by its search158 of them list Dental Caries in their own words; the registry filed them under no condition.
  6. +1
    Counted here, but its search does not find them
  7. 1,168The count on this page

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Status

Completed
670
Status unknown
194
Not yet recruiting
105
Recruiting
86
Active, not recruiting
61
Enrolling by invitation
18

Phase

Phase 2
69
Phase 3
64
Phase 4
53
Phase 1
32
Early Phase 1
16

Where

Egypt
205
United States
193
Turkey
128
Brazil
82
France
29
China
24

Who runs them

Cairo University (151) · University of Sao Paulo (33) · Hacettepe University (27) · Mansoura University (19) · Ain Shams University (17) · Al-Azhar University (17) · King Abdulaziz University (15) · University of California, San Francisco (14)

What is being tested here

Drugs under test in Dental Caries studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Silver diamine fluoride3520
Xylitol124
Midazolam103
Toothpaste113
Sodium Hypochlorite112
Hypochlorous Acid112
Ketamine102
Erythritol112
P-prf102
Anthocyanins101

Coming up

6phase 3 studies under way
69studies finish main data collection within a year2 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 86 Dental Caries studies recruiting now, 18 (21%) set no upper age limit and 66 (77%) stop at 75 or younger. 60 (70%) take children under 18. 1 (1%) are for women only and 1 (1%) for men only; 53 (62%) take healthy volunteers.

Recruiting studies that take each age, of 86
AgeWomenMen
1030 (35%)31 (36%)
1837 (43%)37 (43%)
3033 (38%)32 (37%)
4033 (38%)32 (37%)
5027 (31%)26 (30%)
6525 (29%)24 (28%)
7521 (24%)20 (23%)
8520 (23%)19 (22%)

Across all 1,171 studies, recruiting or not: 79% stop at 75 or younger and 76% at 65; 63% take children; 2% are for women only and 1% for men only; 70% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Dental Caries studies take

Of 25 phase 4 interventional studies under Dental Caries, half reached primary completion within 19 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 113 mo3–18 · 15 studies——
Phase 28 mo3–25 · 20 studies——
Phase 313 mo7–26 · 17 studies——
Phase 419 mo13–31 · 25 studies——
Interventional, no phase15 mo7–29 · 502 studies12 mo3–24 · 33 studies15 mo7–30 · 469 studies
Observational12 mo7–32 · 47 studies—12 mo7–32 · 46 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

Results posted1

Stopped1

Newly registered14

Show 9 more

Studies

Recruiting first, then most recently updated. Showing 50 of 1,171. Browse all 1,171 → or search them.