Tooth Erosion clinical trials
The registry lists 47 studies for Tooth Erosion across 9 countries. 7 are recruiting or about to start. 32 of them are mainly about Tooth Erosion (how this is decided). Per ClinicalTrials.gov, last updated 2026-07-22.
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Status
Who runs them
GlaxoSmithKline (6) · Universidad de los Andes, Chile (4) · University of Pavia (3) · University of Göttingen (3) · Indiana University (2) · University Ghent (2) · Brain-Gut Research Group (2) · University of Bergen (2)
What is being tested here
Drugs under test in Tooth Erosion studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 2
- Oct 2027Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated. · Indiana University
- Nov 2027A Study of Tooth Erosion in People With Esophagogastric Cancer · Memorial Sloan Kettering Cancer Center
Who these studies take
Of the 3 Tooth Erosion studies recruiting now, 1 (33%) set no upper age limit and 2 (67%) stop at 75 or younger. 1 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (33%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (33%) | 1 (33%) |
| 18 | 3 (100%) | 3 (100%) |
| 30 | 2 (67%) | 2 (67%) |
| 40 | 2 (67%) | 2 (67%) |
| 50 | 1 (33%) | 1 (33%) |
| 65 | 1 (33%) | 1 (33%) |
| 75 | 1 (33%) | 1 (33%) |
| 85 | 1 (33%) | 1 (33%) |
Across all 47 studies, recruiting or not: 66% stop at 75 or younger and 49% at 65; 23% take children; 2% are for women only and 0% for men only; 79% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tooth Erosion studies take
Of 20 interventional studies with no phase under Tooth Erosion, half reached primary completion within 6 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 6 mo1–28 · 20 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 47 of 47. search them.
- Salivary Function and Dental Changes During GLP-1 TherapyNot yet recruitingNCT077204661 country
- Obesity and Oral Diseases in Adult PatientsNot yet recruitingNCT04602572
- Multi-site Study to Look at Tooth Wear and Tooth Sensitivity and the Risk Factors Associated.RecruitingNCT071953571 country
- Hydroxyapatite Toothpastes and Enamel Remineralization:RecruitingNCT07069218Not applicable1 country
- Oral Indicators for ED ScreeningRecruitingNCT072951971 country
- The Effect of Chlorhexidine on the Oral Microbiome and Saliva in Dental ErosionNot yet recruitingNCT06171594Not applicable1 country
- The Effect of Nitrate Supplement on the Oral Microbiome and Saliva in Dental ErosionEnrolling by invitationNCT06156618Not applicable1 country
- Quantitative In Vivo Monitoring of Early Erosion-Associated Enamel Optical Changes Using Swept-Source Optical Coherence Tomography.CompletedNCT07690644Not applicable
- 3D Scanning as an Advanced Tool for Identifying Tooth Lesions in ChildrenCompletedNCT06829550Not applicable1 country
- A Study of Tooth Erosion in People With Esophagogastric CancerActive, not recruitingNCT05612048Not applicable1 country
- Effect of Smoking on Saliva Composition and the Development of Dental ErosionCompletedNCT042088021 country
- Maintaining Oral Health With Bio-productsCompletedNCT04033263Not applicable1 country
- Effect of Wet and Overwet Dentin on the Clinical Performance of Two Universal Adhesive SystemsCompletedNCT07034235Not applicable1 country
- An Erosion Study to Investigate the Efficacy of an Experimental Dentifrice to Remineralize EnamelCompletedNCT06242444Not applicable1 country
- Domiciliary Management of Dental Erosion in Patients With GERD With Biomimetic HydroxyapatiteCompletedNCT05371717Not applicable1 country
- Assessment of Oral Health Status of Children With Primary Ciliary DyskinesiaCompletedNCT066182091 country
- Evaluation of Double Layer Application Using a Universal Adhesive in the Quality of Cervical Lesions RestorationsCompletedNCT06474494Not applicable1 country
- Evaluation of the Reduced Dentin Etching Time Using Universal Adhesives in the Quality of Cervical Lesions RestorationsCompletedNCT06465849Not applicable1 country
- Influence of Gender Specific Differences of Saliva Composition on the Development of Dental Erosion - an In-situ StudyCompletedNCT027809731 country
- Investigate a Varnish to Protect From Erosive ToothwearCompletedNCT06136754Phase 31 country
- Evaluation of the Solvent Evaporation Time of Universal Adhesives in the Quality of Cervical Lesions RestorationsCompletedNCT05945173Not applicable1 country
- Carnosine Supplementation on Quantity/Quality of Oral Salivae.Status unknownNCT04295525Not applicable1 country
- A New Protocol for the Management of Dental Erosion in Rugby PlayersCompletedNCT05140538Not applicable1 country
- 12 Months Clinical Follow-up of Non-Carious Cervical Lesions Restored With New Injectable CompositeCompletedNCT04095520Not applicable1 country
- Associations Between Obesity, Dental Caries, Erosive Tooth Wear and Periodontal Disease in Adolescents: A Case Control-studyCompletedNCT05146557
- Gastro-oesophageal Reflux in Oligosymptomatic Patients With Dental ErosionStatus unknownNCT020873451 country
- Dental Erosion in Patients With Gastro-oesophageal RefluxSuspendedNCT02775149
- Relationship Between Gastroesophageal Reflux Disease and Dental ErosionCompletedNCT045955001 country
- Association Between Erosive Tooth Wear Progression and Dietary Risk Factors.CompletedNCT045863221 country
- In Situ Erosion Study to Investigate the Effectiveness of an Experimental ToothpasteCompletedNCT03296072Phase 31 country
- Preventing Early Childhood Obesity, Part 1: Family Spirit Nurture, 3-9 MonthsCompletedNCT03101943Not applicable1 country
- The Effect of Vinegar Consumption on Visceral Fat and Blood Glucose ConcentrationCompletedNCT03577834Not applicable
- The Effects of Mouthguard and Desensitizing Toothpaste in Reducing Dental HypersensitivityCompletedNCT03515902Not applicable1 country
- Pilot Study Utilising an Impression Technique to Capture in Vivo Images of TeethCompletedNCT02676219Not applicable1 country
- Casein Phosphopeptide--amorphous Calcium Phosphate on Human Enamel Subjected to in Vivo Acid AttacksCompletedNCT03426150Phase 4
- Clinical Evaluation of Ultrathin Occlusal Veneers for the Treatment of Severe Dental ErosionStatus unknownNCT03112278Not applicable
- Oral Health Intervention Program for Children With Congenital Heart DefectsCompletedNCT03311438Not applicable
- In Vivo Investigation of Initial Stages of Enamel ErosionCompletedNCT02533466Not applicable1 country
- Intra Oral Kinetics of Fluoride Containing DentifricesCompletedNCT02548156Not applicable1 country
- Experimental Dentifrice Remineralization/Fluoride Uptake in an in Situ ModelCompletedNCT00752089Phase 2
- Prophylactic Effect of a CANDIDA Mouthwash, Containing the Curolox™ PeptideWithdrawnNCT02308436Not applicable1 country
- Evaluation of Efficacy of Experimental Gel to Foam Dentifrices in Dental ErosionCompletedNCT01657903Not applicable1 country
- Evaluation of a Test Mouthwash and Dentifrice Regimen in an In-situ Model of Dental ErosionCompletedNCT01128972Phase 21 country
- In Vivo Quantification of Dental Demineralisation Using OCT With and Without EsomeprazoleCompletedNCT00564330Phase 1/2
- Impact of Milk on Erosion/Abrasion of Enamel and Dentin - an in Situ StudyCompletedNCT01566357Not applicable1 country
- Preliminary Clinical Study of Ultrasound to Measure Enamel ThicknessCompletedNCT01622920Phase 11 country
- Relationship and Pathophysiology of Gastroesophageal Reflux and Dental/Periodontal DiseaseCompletedNCT011675431 country