Pittsburgh compound B clinical trials
How each study uses Pittsburgh compound B is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your alerts, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Approvals
The first approval found in each region, with its record
- United States
- Not in FDA's approval records
- European Union
- Not in EMA's list of EU-wide authorizations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
16 studies that test it; most in 2012 (3)
| Year | Studies |
|---|---|
| 2008 | 1 |
| 2010 | 1 |
| 2012 | 3 |
| 2013 | 1 |
| 2014 | 1 |
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2019 | 2 |
| 2020 | 3 |
| 2023 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 1 · Other 15
Mayo Clinic (7) · University of North Carolina, Chapel Hill (1) · Vanderbilt University Medical Center (1) · University of Pittsburgh (1) · Johns Hopkins University (1) · Avid Radiopharmaceuticals (1) · Peking Union Medical College Hospital (1) · National Institute of Mental Health (NIMH) (1)
Often tested with
Tested in the same studies.
PIB C-11 (3) · Florbetapir (1) · Flortaucipir (1) · ER-176 C-11 (1) · Florquinitau F-18 (1)
Related medicines
As reviewed, each with the page that says it.
- One of Radiopharmaceuticals source
- Often written with PIB C-11 in studies. How it relates to Pittsburgh compound B is not confirmed, so neither page counts the other. source
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 3
Studies that test Pittsburgh compound B.
- Dec 2026Quantitative Imaging of Brain Glymphatic Function in HumansEarly Phase 1 · Vanderbilt University Medical Center
- Mar 2027Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal StudyNot applicable · Mayo Clinic
- Jun 2027Imaging of Brain Amyloid Plaques in the Aging PopulationPhase 4 · Mayo Clinic
Studies
Open first, then newest update. How each study uses Pittsburgh compound B is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 16
- Beta-amyloid PET/CT to Measure Potential Therapeutic Response in AL-CARecruitingPhase 2Peking Union Medical College HospitalNCT07829705Written as 11C-PIB
- A Study of Imaging in Demyelinating DiseasesEnrolling by invitationPhase 2Mayo ClinicNCT05805839Written as C11 Pittsburgh Compound B
- Molecular and Structural Imaging in Alzheimer's Disease: A Longitudinal StudyRecruitingNot applicableMayo ClinicNCT02740634Written as C-11 PiB
- Imaging of Brain Amyloid Plaques in the Aging PopulationEnrolling by invitationPhase 4Mayo ClinicNCT00950430Written as Pittsburgh Compound B (C-11 PiB)
- NFL LONG Prospective StudyActive, not recruitingPhase 1University of North Carolina, Chapel HillNCT04263337Written as [11C] PiB
- Quantitative Imaging of Brain Glymphatic Function in HumansActive, not recruitingEarly Phase 1Vanderbilt University Medical CenterNCT04768101Written as [11C]-PIB
- [C-11]PiB PET Imaging in Alcohol Use DisordersCompletedEarly Phase 1University of PittsburghNCT03746366Written as Pittsburgh Compound B
- PET Imaging of Neuroinflammation in Neurodegenerative Diseases Via a Novel Translocator Protein (TSPO) RadioligandTerminatedPhase 1National Institute of Mental Health (NIMH)NCT03958630Written as 11C-PIB
- Brain Imaging in the Diabetes Prevention Program Outcomes StudyTerminatedEarly Phase 1José A. LuchsingerNCT03757910Written as 11C-PIB
- PET Imaging Study Using [11C]PIB in Subjects With AD & Healthy VolunteersCompletedPhase 1Johns Hopkins UniversityNCT01826110Written as [11C]PIB
- 11C-PIB PET/CT in Patients With Parkinson's Disease and Parkinsonian Dementia SyndromesStatus unknownPhase 2Oriental Neurosurgery Evidence-Based-Study TeamNCT03555292Written as 11C-PiB
- Bridging Study of C11 Pittsburgh Compound B (PiB) and F18 Flutemetamol Brain Positron Emission Tomography (PET)CompletedPhase 2Mayo ClinicNCT01607476Written as C11 PiB
- Florbetapir Calibration to the Centiloid ScaleCompletedPhase 1Avid RadiopharmaceuticalsNCT02120664Written as 11C-PiB
- PiB PET Scanning in Speech and Language Based DementiasCompletedPhase 1Mayo ClinicNCT01623284Written as C-11 PiB
- Amyloid-related Imaging Abnormalities (Microbleeds) in Atypical ADCompletedPhase 1Mayo ClinicNCT01723553Written as C-11 PiB
- Normative Values for Cognitive Testing and Alzheimer's Imaging Biomarkers in Young AdultsCompletedPhase 1Mayo ClinicNCT01609335Written as C-11 PiB