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Biological

P-prf clinical trials

studies test it
61
open now
14
in phase 3
4
first study started
2012

How each study uses p-prf is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study

Get an email when these change. Save the p-prf studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.

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Example · made-up studies

Breast cancer · Recruiting: 2 came in, 3 changed

What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

Came in · now Recruiting

Drug B with hormone therapy in advanced breast cancer

Changed

· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

Exercise during chemotherapy

Now Active, not recruiting

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Approvals

The first approval found in each region, with its record

United States
Not in FDA's approval records
European Union
Not in EMA's list of EU-wide authorisations

From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out

How studies write it

Studies that test it under each name

Name

Platelet rich fibrin
22
PRF
14
Platelet-rich fibrin (PRF)
12
Injectable PRF
4
PRF group
3

Studies by the year they started

61 studies that test it; most in 2025 (12)

Studies that test p-prf, by start year
YearStudies
20121
20134
20141
20152
20163
20173
20183
20195
20203
20214
20223
20231
202411
202512
20265

By phase

A phase 1/2 study counts in both.

Early Phase 1
3
Phase 1
3
Phase 2
9
Phase 3
4
Phase 4
6
No phase
39

What it is tested for

Each study’s main condition, where its own words name it, so a study counts once.

Pain, Postoperative
6
Periodontitis
3
Tooth, Impacted
2
Tooth Fractures
2
Chronic Periodontitis
2
Dry Socket
1
Furcation Defects
1
Tooth Loss
1
Striae Distensae
1
Root Resorption
1
Pulpitis
1
Infections
1

Who runs them

Industry 0 · Other 61

Cairo University (7) · Amerigo Giudice (2) · Ain Shams University (2) · Government Dental College and Research Institute, Bangalore (2) · Federal University of São Paulo (2) · CMH Lahore Medical College and Institute of Dentistry (1) · Inonu University (1) · Medical University of Sofia (1)

Often tested with

Tested in the same studies.

Platelet rich plasma (4) · Hyaluronic Acid (2) · Simvastatin (1) · Turmeric extract (1) · Curcuma longa (1) · Lutein (1) · Zeaxanthins (1) · Bone Graft (1)

Coming up

From the study records. Dates are the sponsors’ own estimates and often move.

Reaching primary completion within a year · 5

Studies that test p-prf.

Studies

Open first, then newest update. How each study uses p-prf is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.

Testing it · 61

See all 61 studies that test p-prf →

Given beside what is tested · 3 — p-prf is usual care or a partner of the new treatment
As the comparator · 6 — what is tested is compared with p-prf