Tooth Loss clinical trials
The registry lists 165 studies for Tooth Loss across more than 10 countries. 44 are recruiting or about to start. 139 of them are mainly about Tooth Loss (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
Get an email when these change. Save the Tooth Loss studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
Mansoura University (10) · Cairo University (10) · Institut Straumann AG (6) · Ege University (4) · Suez Canal University (4) · University of Bari Aldo Moro (3) · University of Iowa (3) · University of Liege (3)
What is being tested here
Drugs under test in Tooth Loss studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dibotermin alfa | 1 | 0 | 1 |
| Enamel matrix proteins | 1 | 0 | 1 |
| P-prf | 0 | 0 | 1 |
| Simvastatin | 0 | 0 | 1 |
| Acellular Dermal Matrix | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Removable Partial Dentures Made of PEEK · University Hospital Heidelberg
- Dec 2026Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket Classes · Plovdiv Medical University
- Dec 2026Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic Zone · Loma Linda University
- Dec 2026Influence of Implant Insertion Depth on Peri-implant Bone Changes Around Short Implants · Gulf Medical University
- Jan 2027Clinical Evaluation of Immediate Dental Implants in Very Elderly Patients. · Takane Dental Clinic
- Jan 2027Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown Prosthesis · Mansoura University
- Feb 2027Influence of Vertical Implant Position on Marginal Bone Loss in Cases With Thin Phenotype · Cairo University
- Mar 2027Evaluation of Enamel Matrix Derivative in Immediate Dental Implants in the Mandibular Molar Region · Mansoura University
- Mar 2027PMCF Study on The Performance and Safety of ON DENT® PMMA Discs/Blocks and Resin Products for Temporary Restorations · On Dent Tibbi Malzeme Dis Protez Ith. ve Ihr. San. Ltd. Sti.
- Mar 2027Effect of Ascorbic Acid-Loaded I-PRF With Partially Demineralized Dentin Graft on Alveolar Ridge Preservation · Nahda University
Who these studies take
Of the 27 Tooth Loss studies recruiting now, 19 (70%) set no upper age limit and 7 (26%) stop at 75 or younger. 4 (15%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 8 (30%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (15%) | 4 (15%) |
| 18 | 23 (85%) | 23 (85%) |
| 30 | 24 (89%) | 24 (89%) |
| 40 | 24 (89%) | 24 (89%) |
| 50 | 23 (85%) | 23 (85%) |
| 65 | 24 (89%) | 24 (89%) |
| 75 | 23 (85%) | 23 (85%) |
| 85 | 19 (70%) | 19 (70%) |
Across all 165 studies, recruiting or not: 35% stop at 75 or younger and 26% at 65; 10% take children; 0% are for women only and 0% for men only; 48% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Tooth Loss studies take
Of 77 interventional studies with no phase under Tooth Loss, half reached primary completion within 28 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 28 mo12–48 · 77 studies | — | 28 mo12–48 · 71 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 165. Browse all 165 → or search them.
- Safety Assessment of Placing a Single Dental Implant Without Antibiotic Prophylaxis in Simple Cases: A Pilot StudyNot yet recruitingNCT07920614Not applicable1 country
- Effect of Ascorbic Acid-Loaded I-PRF With Partially Demineralized Dentin Graft on Alveolar Ridge PreservationNot yet recruitingNCT07916545Not applicable
- Investigation of the Effect of Horizontal Platelet Rich Fibrin Placed in Tooth Extraction Sockets on Bone FormationEnrolling by invitationNCT07011303Not applicable1 country
- Changes in Oral Health-related Quality of Life (OHRQoL) During Full Arch Implant TreatmentRecruitingNCT075682491 country
- Immediate vs Conventional Loading With Different Crown Materials on Immediately Placed Single ImplantsNot yet recruitingNCT07882095Not applicable1 country
- One vs Two Visits Root Canal Treatments in Infected TeethRecruitingNCT04605445Not applicable1 country
- Bone and Soft Tissue Healing After Socket Preservation With NOVAMag or Permamem MembranesNot yet recruitingNCT07856693Not applicable1 country
- Ti-Mesh Frame Comparison for Alveolar Bone AugmentationEnrolling by invitationNCT06077513Not applicable1 country
- Evaluation of Enamel Matrix Derivative in Immediate Dental Implants in the Mandibular Molar RegionRecruitingNCT07727655Not applicable1 country
- Volumetric Efficacy of Alveolar Ridge PreservationRecruitingNCT07812883Not applicable1 country
- Clinical Evaluation of Immediate Dental Implants in Very Elderly Patients.Enrolling by invitationNCT078013391 country
- Immediate Molar Implants With Customized Healing Abutments in Different Post-Extraction Socket ClassesRecruitingNCT078015731 country
- Clinical Performance of Nobel N1 SystemRecruitingNCT07280260Phase 41 country
- Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)Not yet recruitingNCT07748871Not applicable1 country
- A Clinical Study of the TSX Dental Implant System (Xpresso)RecruitingNCT065718121 country
- Tissue Preservation in Immediate 1C Implants Using an Anatomical Prefabricated Healing AbutmentNot yet recruitingNCT07727980Not applicable1 country
- Soft Tissue Augmentation Around Dental Implants Using Connective Tissue Graft, Submerged Tenting Abutment, or Sub-crestal Implant PlacementRecruitingNCT07714265Not applicable1 country
- Standard- and Micro-Dose rhBMP-2 for Implant Stability, Marginal Bone Loss, and Postoperative Sequelae: A Double-Blind Randomized Controlled TrialNot yet recruitingNCT07696299Not applicable1 country
- Rigid Versus Non-Rigid Digitally Fabricated Telescopic Double Crown ProsthesisNot yet recruitingNCT07682623Not applicable
- PMCF Study on The Performance and Safety of ON DENT® PMMA Discs/Blocks and Resin Products for Temporary RestorationsRecruitingNCT07632443Not applicable1 country
- PMCF Study on the Effectiveness and Safety of BIODENTOSS® and DWC® Dental Implants and SuperstructuresRecruitingNCT07633665Not applicable1 country
- Allogenic Bone Block for Oro-Antral Communication Closure for Subsequent Implant PlacementEnrolling by invitationNCT07604142Not applicable1 country
- Clinical Safety and Effectiveness of the Straumann Dynamic Navigation System FalconRecruitingNCT07518615Not applicable4 countries
- Influence of Vertical Implant Position on Marginal Bone Loss in Cases With Thin PhenotypeRecruitingNCT07483086Not applicable1 country
- Effect of Mandibular Drilling Speed on Implant Stability and Osteogenic Potential: A Randomized Clinical TrialNot yet recruitingNCT07475416Not applicable
- Mandibular Biological Drilling at Different Speeds for Dental Implant PlacementNot yet recruitingNCT07474454Not applicable
- Peri-implant Mucosal Changes Over Time Following Implant Provisional Removal in the Esthetic ZoneRecruitingNCT067835951 country
- Autogenous Tooth Transplantation With Instrumentally Simulated Open Apex and Platelet-Rich FibrinRecruitingNCT07393997Not applicable1 country
- Primary Stability and Peri-implant Outcomes of Short Implants in Post-extraction Single-tooth SitesRecruitingNCT07177521Not applicable1 country
- DEntal implaNt Set: Development and Implementation of a Standardized Outcome Set in Implant DentistryRecruitingNCT073370571 country
- In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided SurgeryRecruitingNCT07315607Not applicable1 country
- Clinical and Radiological Evaluation of Dental Autotransplantation in the Anterior Region in Young PatientsRecruitingNCT073145801 country
- LT Comparative Effectiveness of 2 Caries TreatmentsRecruitingNCT07213661Not applicable1 country
- Efficacy of Bioactive Glass vs. Xenograft in Maxillary Sinus AugmentationNot yet recruitingNCT07125846Not applicable
- Space Changes After Premature Loss of Lower First Primary Molars in Children Using Digital ScanningNot yet recruitingNCT069657771 country
- 3D Autotransplantation of TeethRecruitingNCT04120688Not applicable1 country
- Evaluation of 3D-printed Space Maintainers Versus Conventional Space Maintainer : a Randomized Clinical TrialNot yet recruitingNCT06750068Not applicable
- Research on the Development and Clinical Evaluation of Biomimetic AbutmentsRecruitingNCT06870955Not applicable1 country
- Influence of Healing Time on the Outcomes of Alveolar Ridge Preservation in Periodontally Compromised Extraction SocketsRecruitingNCT06654141Not applicable1 country
- A 36-month Analysis of the Clinical Performance of Individualized CAD/CAM-produced Dental Implants: a Cohort StudyRecruitingNCT065762841 country
- Removable Partial Dentures Made of PEEKRecruitingNCT06191107Not applicable1 country
- Primary and Secondary Elevations of Maxillary Sinuses: a Prospective Clinical Study in the Posterior Maxillary RegionRecruitingNCT06106321Not applicable1 country
- 5-Years PMCF Study of Ceramic Dental Implants One-piece Versus Two-piece.RecruitingNCT062873462 countries
- The Effect of Pre-operative Single Dose Antibiotic Prophylaxis on the Post-operative Implant SuccessRecruitingNCT04856319Not applicable1 country
- Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic ZoneCompletedNCT07468760Not applicable1 country
- Influence of Implant Insertion Depth on Peri-implant Bone Changes Around Short ImplantsActive, not recruitingNCT07468747Not applicable1 country
- 3D-Printed Versus Band-and-Loop Versus Denovo Space Maintainers in Primary Dentition.Active, not recruitingNCT07613658Not applicable1 country
- Sleeved vs. Sleeveless Guides for Immediate Implant PlacementActive, not recruitingNCT07845890Not applicable1 country
- Silicate β-TCP vs Extended Sticky Bone for Peri-Implant Jumping Gap in Guided Immediate Implants: RCTCompletedNCT07700706Not applicable1 country
- Silicate-Added Beta-TCP in Fully Guided Immediate Implants in the Esthetic ZoneCompletedNCT07613320Not applicable1 country