Furcation Defects clinical trials
The registry lists 42 studies for Furcation Defects across more than 10 countries. 13 are recruiting or about to start. 33 of them are mainly about Furcation Defects (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-15.
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Who runs them
Government Dental College and Research Institute, Bangalore (5) · University of Oslo (4) · University of Medicine and Pharmacy at Ho Chi Minh City (3) · King's College London (2) · Cairo University (2) · Postgraduate Institute of Dental Sciences Rohtak (2) · Minia University (1) · Hams Hamed Abdelrahman (1)
What is being tested here
Drugs under test in Furcation Defects studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Enamel matrix proteins | 0 | 0 | 2 |
| P-prf | 0 | 0 | 1 |
| Rosuvastatin | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5, phase 3 first
- May 2027Treatment of Class II Mandibular Furcation Defects · Phase 3 · Cairo University
- Mar 2027Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Grade II Furcation Defects · October 6 University
- Jun 2027Efficacy of PRF and Xenograft in Treating Mandibular Molar Furcation Involvements · University of Medicine and Pharmacy at Ho Chi Minh City
- Aug 2027Effect of Mobile Health on Plaque Control Efficacy in Molars With Furcation Involvement · Postgraduate Institute of Dental Sciences Rohtak
- Sep 2027Enamel Matrix Derivative and Xenograft for Mandibular Molar Furcation Defects · University of Medicine and Pharmacy at Ho Chi Minh City
Who these studies take
Of the 10 Furcation Defects studies recruiting now, 9 (90%) set no upper age limit and 1 (10%) stop at 75 or younger. 1 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (10%) | 1 (10%) |
| 18 | 10 (100%) | 10 (100%) |
| 30 | 10 (100%) | 10 (100%) |
| 40 | 10 (100%) | 10 (100%) |
| 50 | 10 (100%) | 10 (100%) |
| 65 | 10 (100%) | 10 (100%) |
| 75 | 9 (90%) | 9 (90%) |
| 85 | 9 (90%) | 9 (90%) |
Across all 42 studies, recruiting or not: 43% stop at 75 or younger and 36% at 65; 10% take children; 0% are for women only and 0% for men only; 57% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 42 of 42. search them.
- Treatment of Class II Mandibular Furcation DefectsRecruitingNCT07876973Phase 31 country
- Injectable Platelet-Rich Fibrin With Minimally Invasive Non-Surgical Technique in Treatment of Grade II Furcation DefectsRecruitingNCT07787949Not applicable1 country
- Enamel Matrix Derivative and Xenograft for Mandibular Molar Furcation DefectsRecruitingNCT07776756Not applicable1 country
- Morphological Characteristics of Mandibular Molar Furcation Involvement and Efficacy of Regenerative Surgical TreatmentRecruitingNCT07770256Not applicable1 country
- Efficacy of PRF and Xenograft in Treating Mandibular Molar Furcation InvolvementsRecruitingNCT07764029Not applicable1 country
- Effect of Mobile Health on Plaque Control Efficacy in Molars With Furcation InvolvementNot yet recruitingNCT07642895Not applicable1 country
- A Chitosan Brush and Enamel Matrix Derivative for Non-surgical Treatment of FurcationsRecruitingNCT06684769Not applicable1 country
- Use of a Bone Substitute Material in the Surgical Therapy of Furcation DefectsRecruitingNCT06270303Not applicable1 country
- Evaluation of Outcomes of Minimally Invasive Non- Surgical Versus Surgical Therapy in Furcation Involvement.RecruitingNCT06025955Not applicable1 country
- Clinical and Radiographic Outcomes of Class II Furcation Defects Management Using Propolis: A Case SeriesRecruitingNCT06060340Early Phase 11 country
- MRI as Alternative to CBCT for the Assessment of Furcation Involvement in MolarsNot yet recruitingNCT061164871 country
- Vital Root Amputation in Molars With Advanced Periodontal Furcation Involvement: a Preliminary StudyNot yet recruitingNCT05721313Not applicable1 country
- Flapless Application of Enamel Matrix Derivative in Class II Mandibular Furcation DefectsRecruitingNCT05541614Not applicable1 country
- PRF Versus Emdogain for Class II Furcation Defects of Mandibular MolarsCompletedNCT07841301Not applicable1 country
- Effect of Two Irrigation Protocols Applied Prior to Furcation RepairCompletedNCT06757660Not applicable1 country
- Effectiveness of E-prf Alone and in Combination With Bioactive Glass Nanoparticles in Grade II Furcation DefectsCompletedNCT07042204Not applicable1 country
- Bovine Pericardium Membrane Versus Native Collagen Membrane in Conjunction With Sticky Bone Graft in Treatment of Class II Furcation Defects in Lower Molars.Active, not recruitingNCT06681532Not applicable1 country
- Non-surgical vs. Surgical Therapy for Periodontal FurcationsActive, not recruitingNCT05237401Not applicable1 country
- Comparison of Bone Graft and Photodynamic Therapy in Class II FurcationCompletedNCT06519409Not applicable1 country
- Treatment of Advanced Grade III Periodontal Furcation LesionsActive, not recruitingNCT05237739Not applicable1 country
- Mandibular Furcation II RegenerationTerminatedNCT04059445Phase 41 country
- Mandibular Furcation III Regeneration (FURC-III-REGEN)TerminatedNCT04059458Phase 41 country
- Vital Root-resective Therapy in Furcation-involved Maxillary MolarsActive, not recruitingNCT05259982Not applicable1 country
- Restorations and Furcation Involvement on MolarsStatus unknownNCT054815801 country
- Evaluate the Effect of Hyaluronic Acid in the Treatment of Furcation InvolvementStatus unknownNCT04851548Not applicable
- Added Benefit of L-PRF to Autogenous Bone Graft in the Treatment of Mandibular Degree II Furcation DefectsCompletedNCT03756493Not applicable1 country
- Furcation Treatment With L-PRF and aPDTCompletedNCT04842188Not applicable1 country
- Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade II Furcation DefectsWithdrawnNCT03917030Not applicable1 country
- Osteoplasty in Conjunction With Surgical Treatment of Mandibular Grade III Furcation Defects (FURC-III-OST)WithdrawnNCT04017429Not applicable1 country
- Evaluation of Injectable Beta-tricalcium Phosphate Clinically in Treatment of Grade II Furcation InvolvementCompletedNCT04443972Not applicable1 country
- Comparison of Platelet Rich Fibrin as Graft & Membrane Vs Hyaluronic Acid & Amniotic Membrane in the Treatment of Interradicular DefectsCompletedNCT03578744Not applicable1 country
- Surgical Treatment of Mandibular Furcations Using a Xenograft With/Without a Collagen MembraneCompletedNCT03354182Not applicable
- PRF+1% MF for Class II Mandibular Furcation DefectsCompletedNCT03207698Phase 2/31 country
- Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in HumansStatus unknownNCT03180658Not applicable1 country
- Benefits of Platelet Rich Fibrin In Mandibular Molar Furcation DefectsCompletedNCT02430519Not applicable
- Piezosurgery in the Treatment of Class II Furcation InvolvementStatus unknownNCT02132806Not applicable1 country
- Boric Acid in Degree 2 Furcation DefectCompletedNCT02738515Phase 2/31 country
- Platelet Rich Fibrin+1.2% Atorvastatin in Treatment of Mandibular Degree II Furcation DefectsCompletedNCT02612792Phase 2/31 country
- Platelet Rich Fibrin+1% Alendronate in Treatment of Mandibular Degree II Furcation DefectsCompletedNCT02609061Phase 2/31 country
- Rosuvastatin Gel With 1:1 Mixture of Platelet-rich Fibrin and Bone Graft in Mandibular Degree II Furcation DefectsCompletedNCT02369250Phase 4
- Effect of Laser Use on Guided Tissue Regeneration in Treatment of Molar Teeth With Class 2 Furcation Affected by PeriodontitisCompletedNCT01522131Not applicable1 country
- Conventional or Minimally Invasive Surgical Technique for the Treatment of Furcation Defects Using Enamel Matrix Derivative and Anorganic Bovine Bone - a Randomized Controlled Clinical Trial.CompletedNCT02102360Phase 41 country