Vaginosis, Bacterial clinical trials
The registry lists 240 studies for Vaginosis, Bacterial across more than 10 countries. 39 are recruiting or about to start. 205 of them are mainly about Vaginosis, Bacterial (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-26.
Get an email when these change. Save the Vaginosis, Bacterial studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
See an example email
Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
One email a week for all your saved searches. Stop any time.
Status
Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (8) · Starpharma Pty Ltd (6) · University of Pittsburgh (5) · Skaraborg Hospital (4) · Vaginal Biome Science (4) · University of Alabama at Birmingham (4) · Gedea Biotech AB (4) · Peter Humaidan (3)
What is being tested here
Drugs under test in Vaginosis, Bacterial studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Metronidazole | 2 | 4 | 21 |
| Clindamycin | 1 | 1 | 6 |
| Secnidazole | 1 | 2 | 5 |
| Azithromycin | 1 | 2 | 3 |
| Ceftriaxone | 1 | 1 | 1 |
| Clotrimazole | 1 | 1 | 1 |
| Doxycycline | 1 | 1 | 1 |
| Lactobacillus acidophilus/Estriol Vaginal Tablet | 1 | 0 | 1 |
| Astodrimer | 0 | 4 | 6 |
| Tinidazole | 0 | 1 | 5 |
Drug classes tested here Hormonal contraceptives 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Apr 2027Study to Evaluate Efficacy and Safety of Gyntima® Balance in Preventing Recurrences of Bacterial Vaginosis · Phase 3 · Kaneka Americas Holding Inc.
- Nov 2026Efficacy and Safety of a Vaginal Ovule Medical Device for Bacterial Vaginosis and Candidal Vaginitis (ROVUL25). · ROELMI HPC
- Dec 2026Vaginal Microbiome Transplantation for Recurrent Bacterial Vaginosis · Hadassah Medical Organization
- Dec 2026The Genital Microbiome of Male Partners of Women With Recurrent BV Undergoing Vaginal Microbiome Transplantation · Hadassah Medical Organization
- Dec 2026Large Algorithm Setting and Validation Study · Nanopath, Inc
- Dec 2026Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis · BioClin BV
- Dec 2026A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial Vaginosis · Peking University Shenzhen Hospital
- Jan 2027A Randomized, Multicenter, Open-label, Active-controlled Phase Ib Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Multiple Intravaginal Doses of GenSci142 in Patients With Bacterial Vaginosis (BV) · Changchun GeneScience Pharmaceutical Co., Ltd.
- Jan 2027Efficacy and Safety Study of BPR-101 Capsules in Combination With Metronidazole in BV Patients · Chengdu Syncor Pharmaceutical Co., Ltd.
- Jan 2027Vaginal Microbiota Transplant · Douglas Kwon
Who these studies take
Of the 23 Vaginosis, Bacterial studies recruiting now, 7 (30%) set no upper age limit and 16 (70%) stop at 75 or younger. 2 (9%) take children under 18. 21 (91%) are for women only and 1 (4%) for men only; 9 (39%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (4%) | 0 (0%) |
| 18 | 20 (87%) | 2 (9%) |
| 30 | 22 (96%) | 2 (9%) |
| 40 | 22 (96%) | 2 (9%) |
| 50 | 16 (70%) | 2 (9%) |
| 65 | 9 (39%) | 2 (9%) |
| 75 | 7 (30%) | 2 (9%) |
| 85 | 6 (26%) | 2 (9%) |
Across all 240 studies, recruiting or not: 68% stop at 75 or younger and 67% at 65; 13% take children; 98% are for women only and <1% for men only; 35% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Vaginosis, Bacterial studies take
Of 17 phase 4 interventional studies under Vaginosis, Bacterial, half reached primary completion within 23 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 26 mo19–41 · 14 studies | — | — |
| Phase 3 | 9 mo5–25 · 12 studies | — | — |
| Phase 4 | 23 mo13–41 · 17 studies | — | — |
| Interventional, no phase | 12 mo5–56 · 52 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 14, 2026.
Started recruiting1
Newly registered4
- Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial VaginosisOct 26, 2026NCT07893782
- Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal ClindamycinOct 22, 2026NCT07888101
- WST03 Capsule Combined With Metronidazole for Bacterial VaginosisOct 22, 2026NCT07888699
- A Study to Test New Investigational Drugs (LCFA-01and LC103) for Bacterial Vaginosis (BV) TreatmentOct 15, 2026NCT07875673
Studies
Recruiting first, then most recently updated. Showing 50 of 240. Browse all 240 → or search them.
- Prevention of Vaginal Cuff Infection After Hysterectomy by Addition of Vaginal ClindamycinEnrolling by invitationNCT078881011 country
- WST03 Capsule Combined With Metronidazole for Bacterial VaginosisNot yet recruitingNCT07888699Phase 21 country
- A Randomized, Multicenter, Open-label, Active-controlled Phase Ib Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Multiple Intravaginal Doses of GenSci142 in Patients With Bacterial Vaginosis (BV)RecruitingNCT07663838Phase 11 country
- A Study to Test New Investigational Drugs (LCFA-01and LC103) for Bacterial Vaginosis (BV) TreatmentNot yet recruitingNCT07875673Phase 12 countries
- Multi-Gyn FemiTotal for the Treatment and Prevention of Vulvovaginal Candidiasis Symptoms and Bacterial VaginosisRecruitingNCT07234786Not applicable1 country
- Multi-Gyn ActiGel Plus for Treatment of Bacterial VaginosisRecruitingNCT04807842Not applicable1 country
- Photobiomodulation With Blue LED in Recurrent Bacterial VaginosisNot yet recruitingNCT07835815Not applicable
- The Genital Microbiome of Male Partners of Women With Recurrent BV Undergoing Vaginal Microbiome TransplantationRecruitingNCT05963711Not applicable1 country
- Vaginal Microbiota TransplantRecruitingNCT04046900Phase 1/21 country
- Evaluation of the Ability of Lactobacillus Crispatus CRP21 to Reduce the Incidence of Recurrent Bacterial VaginosisRecruitingNCT07474831Not applicable1 country
- AUTOP 2: Screen-and-treat Strategy for Vaginal Flora Abnormalities by Molecular Biology in Pregnant Women at High Risk of Preterm BirthNot yet recruitingNCT06349122Phase 3
- Chlorhexidine and/or Metronidazole Plus FB301 Pre-treatment TrialRecruitingNCT07481955Phase 21 country
- Large Algorithm Setting and Validation StudyRecruitingNCT076074701 country
- Efficacy and Safety of a Vaginal Ovule Medical Device for Bacterial Vaginosis and Candidal Vaginitis (ROVUL25).Not yet recruitingNCT07703241Not applicable1 country
- Photobiomodulation for Vaginal Dysfunctions: Home-Based vs Outpatient TreatmentNot yet recruitingNCT07697768Not applicable1 country
- The LISA (Lactoferrin InStead of Antibiotics/Antifungals) Feasibility StudyRecruitingNCT05434104Not applicable1 country
- MOTIF@FRESH: Modifying Organisms Transvaginally in Females @ FRESHNot yet recruitingNCT07566754Phase 21 country
- Refining Treatment Options for Trichomonas Vaginalis Infection: A Comparative Analysis of Metronidazole and SecnidazoleRecruitingNCT06261840Phase 41 country
- Study to Evaluate Efficacy and Safety of Gyntima® Balance in Preventing Recurrences of Bacterial VaginosisNot yet recruitingNCT07527572Phase 2/3
- Impact of Internal Menstrual Protections on Immunity and Vaginal MicrobiotaRecruitingNCT071999981 country
- Efficacy and Safety Study of BPR-101 Capsules in Combination With Metronidazole in BV PatientsNot yet recruitingNCT07483671Phase 21 country
- Exploring the Effects of an Intravaginal Lactic Acid Gel on the Vaginal MicrobiomeRecruitingNCT05753813Early Phase 11 country
- The Effects of Adjunctive Therapy With Vaginal Tablets Lactobacillus Acidophilus and a Low Dose Estriol (Gynoflor®) to Prolong Pregnancy Time in Preterm Labor, A Randomized Controlled TrialNot yet recruitingNCT07344064Not applicable
- A First-in-Human Safety and Pharmacokinetic Trial of GenSci142 Administered as Single Ascending Doses in Healthy Chinese WomenNot yet recruitingNCT07302035Phase 11 country
- Prospective Data Bank Creation to Study Vaginal ConditionsRecruitingNCT018292041 country
- Vaginal Ecosystem and Network in the United States StudyEnrolling by invitationNCT064727652 countries
- A Prospective, Randomized Controlled Study of the Probiotics as Adjuvant Treatment for Bacterial VaginosisRecruitingNCT04771728Phase 41 country
- Evaluation of the Medical Device Vagitab - T as Adjuvant Therapy in Patients With Bacterial Vaginosis.RecruitingNCT06725888Not applicable1 country
- Effect of Lactobacillus Johnsonii or White Pomegranate Extract on the Vaginal HealthRecruitingNCT06069531Not applicable1 country
- Clinical Protocol CERN Feasibility StudyRecruitingNCT06933420Not applicable1 country
- Optimization of Bacterial Vaginosis Treatment in Women of Reproductive AgeRecruitingNCT06458543Phase 41 country
- Effects of Lacticaseibacillus Rhamnosus LRa05 on Bacterial Vaginosis and Ovarian Function in WomenNot yet recruitingNCT06821789Not applicable
- Probiotic Efficacy in Postmenopausal Women with Bacterial VaginosisRecruitingNCT06659380Not applicable1 country
- Efficacy, Safety, and Dose-response of a Live Biotherapeutic Product in Women With Acute Vaginal InfectionNot yet recruitingNCT06450990Phase 1/2
- Precision Vaginal Microbiome Transplantation in Women With Bacterial VaginosisRecruitingNCT06263465Not applicable1 country
- Use of Blue Light Emitting Diode in the Treatment of Women With Bacterial Vaginosis: a Clinical TrialRecruitingNCT03500107Not applicable1 country
- Effect of PreforPro® on Urinary and Vaginal HealthNot yet recruitingNCT05590195Phase 3
- First in Human Study in Healthy Volunteers of Antimicrobial Peptide PL-18 Vaginal SuppositoriesRecruitingNCT05340790Phase 11 country
- The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal MicrobiotaRecruitingNCT05166746Phase 21 country
- Probiotics as an Adjunct to Antibiotics for Recurrent Bacterial VaginosisCompletedNCT07893782Phase 41 country
- Performance Study of the Cobas® BV/CV Test on Samples From Participants With and Without Symptoms of Bacterial Vaginosis and Candida VaginitisCompletedNCT069754363 countries
- A First-in-human Safety Trial of BNT331 Administered as Single Ascending Doses in Healthy Women and as Multiple Ascending Doses in Women Diagnosed With Bacterial VaginosisCompletedNCT06469164Phase 11 country
- Vaginal Flora for Treatment of Bacterial VaginosisCompletedNCT02236429Not applicable1 country
- Impact of Clinician-administered Vaginal Live Biotherapeutic ProductCompletedNCT07305844Early Phase 12 countries
- Vaginal Microbiome Transplantation for Recurrent Bacterial VaginosisActive, not recruitingNCT04517487Phase 1/21 country
- To Test a New Drug (LCFA-01) for Safety and PK in Healthy Adults for Bacterial Vaginosis Infection.Active, not recruitingNCT07514416Phase 11 country
- Single Arm Trial of Menstrual Cups Among Economically Vulnerable Women to Reduce Bacterial Vaginosis and STIsCompletedNCT05666778Phase 22 countries
- A Study to Evaluate the Effects of a Prebiotic and Probiotic Supplement to Provide Relief From Symptoms Associated With Bacterial Vaginosis and Yeast Infections.CompletedNCT06665126Not applicable1 country
- Oral Lactobacillus Crispatus LCr86 Reduces Nugent Score and Improves Vaginal Microecology in Women With Intermediate Vaginal MicrobiotaCompletedNCT06830122Not applicable1 country
- An Open Single-armed Investigation to Evaluate the Safety of pHyph Following a Prolonged Treatment Duration in Adult Women With Bacterial VaginosisCompletedNCT07394777Not applicable1 country