Drug
Melphalan hydrochloride clinical trials
Also written Evomela and HEPZATO.
A product of Melphalan; its studies count on that page too.
Keep track of what changes. Save the melphalan hydrochloride studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
12 studies that test it; most in 2018 (3)
| Year | Studies |
|---|---|
| 2011 | 1 |
| 2013 | 1 |
| 2014 | 1 |
| 2016 | 1 |
| 2017 | 2 |
| 2018 | 3 |
| 2019 | 1 |
| 2022 | 1 |
| 2023 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 1 · Other 11
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (2) · Roswell Park Cancer Institute (1) · Delcath Systems Inc. (1) · Medical College of Wisconsin (1) · M.D. Anderson Cancer Center (1) · University of Washington (1) · Washington University School of Medicine (1) · Children's Oncology Group (1)
Often tested with
Tested in the same studies.
Fludarabine (3) · Fludarabine phosphate (2) · Cytarabine (2) · Cyclophosphamide (1) · Cladribine (1) · Cyclosporine (1) · Filgrastim (1) · Mitoxantrone (1)
Studies
Open first, then newest update. How each study uses melphalan hydrochloride is read from its arms, and is right about nine times in ten.
Testing it · 12
- Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)RecruitingPhase 3Children's Oncology GroupNCT03126916Written as Melphalan Hydrochloride
- Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell TransplantActive, not recruitingPhase 1/2Roswell Park Cancer InstituteNCT03192397Written as Melphalan Hydrochloride
- Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical TransplantationCompletedPhase 2Medical College of WisconsinNCT03159702Written as Evomela
- Melphalan Hydrochloride in Treating Participants With Newly-Diagnosed Multiple Myeloma Undergoing Donor Stem Cell TransplantationCompletedPhase 1/2M.D. Anderson Cancer CenterNCT03417284Written as Melphalan Hydrochloride
- Melphalan on Disease Burden Measured by Next Generation Sequencing Before AHCT (Autologous Hematopoietic Cell Transplant) for Multiple MyelomaWithdrawnEarly Phase 1Koen van BesienNCT05013437Written as Evomela
- An Open-Label Expanded Access Study of the Melphalan/Hepatic Delivery System (HDS) in Patients With Hepatic Dominant Ocular MelanomaActive, not recruitingPhase 3Delcath Systems Inc.NCT05022901Written as Melphalan (3 mg/kg IBW) with Hepatic Delivery System (HDS)
- Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis PatientsTerminatedPhase 2Boston Medical CenterNCT02994784Written as Propylene Glycol-Free Melphalan Hydrochloride
- Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid NeoplasmsCompletedPhase 2University of WashingtonNCT02756572Written as Melphalan Hydrochloride
- Study of Personalized Melphalan Dosing in the Setting of Autologous TransplantWithdrawnPhase 2Ohio State University Comprehensive Cancer CenterNCT03328936Written as Melphalan Hydrochloride
- Intra-arterial Chemotherapy for the Treatment of Progressive Diffuse Intrinsic Pontine Gliomas (DIPG).CompletedPhase 1Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT01688401Written as Melphalan hydrochloride
- Intra-arterial Chemotherapy for the Treatment of Intraocular RetinoblastomaTerminatedPhase 2Sidney Kimmel Comprehensive Cancer Center at Johns HopkinsNCT01293539Written as Melphalan hydrochloride
- Study of Melphalan HCl for Injection (Propylene Glycol-free), Carmustine, Etoposide, Cytarabine (BEAM Regimen) and Autologous Stem Cell Transplantation for LymphomaCompletedPhase 2Washington University School of MedicineNCT01969435Written as Melphalan HCl (propylene glycol-free)
Given in every arm · 1 — melphalan hydrochloride is usual care beside what is tested
Codes
What other systems call melphalan hydrochloride · ClinicalTrials.gg INT014359
- RxNorm 235857One source FDA
- Wikidata Q27252967melphalan hydrochlorideOne source Wikidata
- NCI Thesaurus C48002Melphalan HydrochlorideOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| RxNorm | 235857 | — | One source FDA |
| Wikidata | Q27252967 | melphalan hydrochloride | One source Wikidata |
| NCI Thesaurus | C48002 | Melphalan Hydrochloride | One source FDA |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.