Supplement
Leucine clinical trials
- studies test it
- 48
- open now
- 6
- in phase 3
- 1
- first study started
- 2007
Keep track of what changes. Save the Leucine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Other names
- Leu
- 1
Studies by the year they started
48 studies that test it; most in 2013 (8)
| Year | Studies |
|---|---|
| 2007 | 3 |
| 2008 | 2 |
| 2009 | 1 |
| 2011 | 3 |
| 2012 | 1 |
| 2013 | 8 |
| 2014 | 4 |
| 2015 | 4 |
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 2 |
| 2019 | 3 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 4 |
| 2023 | 1 |
| 2024 | 1 |
| 2025 | 3 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 1
- Phase 1
- 4
- Phase 2
- 9
- Phase 3
- 1
- Phase 4
- 1
- No phase
- 36
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 0 · Other 48
University of Sao Paulo (4) · Maastricht University Medical Center (3) · Nanyang Technological University (2) · The University of Texas Medical Branch, Galveston (2) · University Hospital, Basel, Switzerland (2) · University of Nottingham (2) · Texas A&M University (1) · VA Office of Research and Development (1)
Often tested with
Tested in the same studies.
Isoleucine (10) · Valine (10) · Whey Proteins (3) · Essential amino acid (2) · Carnitine (2) · Arginine (2) · Tryptophan (2) · Xylitol (2)
Studies
Open first, then newest update. How each study uses Leucine is read from its arms, and is right about nine times in ten.
Testing it · 48
- Pilot Study of BCAA on SleepRecruitingNot applicablePortland VA Medical CenterNCT03990909Written as Branched Chain Amino Acids
- Leucine in Midlife DepressionRecruitingPhase 2Emory UniversityNCT06580145Written as L-leucine
- Branched Chain Amino Acids for Sarcopenia in Patients Undergoing Total Knee ArthroplastyRecruitingPhase 4Seoul National University HospitalNCT07634523Written as Livact Granule
- Feasibility Nutritional Supplements for Muscle Growth in CPRecruitingNot applicableUniversitaire Ziekenhuizen KU LeuvenNCT06044168Written as Dietary Supplement: Leucine
- Leucine Supplementation Strategies to Enhance Muscle Anabolic Responses in Older AgeRecruitingNot applicableUniversity of NottinghamNCT06567665Written as Leucine
- LEAN Mass Preservation With Resistance Exercise and Protein During Semaglutide/Tirzepatide TherapyRecruitingNot applicableDasman Diabetes InstituteNCT06885736Written as Protein Intake
- Prandial Metabolic Phenotype in AdultsActive, not recruitingNot applicableTexas A&M UniversityNCT05400733Written as Essential Amino Acids + Leucine
- SmART-TBI: Supplementation With Amino Acid Rehabilitative Therapy in TBICompletedNot applicableVA Office of Research and DevelopmentNCT04603443Written as Branched Chain Amino Acids
- Role of Leucine on Muscle Preservation During Weight Loss in Older MenCompletedNot applicableNanyang Technological UniversityNCT07781410Written as Leucine
- Dose Response of Leucine on Muscle Maintenance During Weight LossCompletedNot applicableNanyang Technological UniversityNCT07583875Written as leucine
- Plasma Trimethylamine N-oxide Elevation Induced by L-carnitine Supplementation and Insulin ResistanceCompletedNot applicablePoznan University of Physical EducationNCT05251207Written as L-leucine
- Evaluation of the Impact of Physical Reconditioning Associated With Specific Nutritional Supplementation in Obese Patients Suffering From Metabolic SyndromeCompletedNot applicableUniversity Hospital, RouenNCT01326416Written as L-Leucine and L-arginine
- BCAA Supplementation for ConcussionCompletedPhase 2Children's Hospital of PhiladelphiaNCT01860404Written as Branched Chain Amino Acids
- Leucine Requirement in Adult Men and WomenCompletedNot applicableThe Hospital for Sick ChildrenNCT05394155Written as Leucine
- Leucine for Depression Study (L-DEP)TerminatedEarly Phase 1University of California, Los AngelesNCT03557684Written as leucine
- Metabolomic Impacts of Branched-chain Amino Acid Supplementation During Endurance ExerciseCompletedNot applicableMontana State UniversityNCT04969536Written as Branched Chain Amino Acids
- Rapid Antidepressant Effects of LeucineTerminatedPhase 2University of Texas Southwestern Medical CenterNCT03079297Written as L-Leucine
- Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan AnemiaCompletedPhase 1/2Northwell HealthNCT01362595Written as leucine
- Nutritional Strategies to Augment the Postprandial Muscle Protein Synthetic Response to the Ingestion of a Low Dose of Protein in Middle-aged WomenCompletedNot applicableUniversity of Illinois at Urbana-ChampaignNCT02918981Written as 6.6 g Whey protein + 1.25 g leucine
- Can Supplemental Leucine Offset Disuse-induced Muscle Atrophy?CompletedNot applicableUniversity of BirminghamNCT03762278Written as Leucine
See all 48 studies that test Leucine →
Given in every arm · 2 — Leucine is usual care beside what is tested
- Carnitine Supplementation and Bone Mineral DensityCompletedNot applicablePoznan University of Physical EducationNCT05120011Written as L-leucine
- The Effect of Leucine on Carnitine Transport to Skeletal MuscleCompletedNot applicableGdansk University of Physical Education and SportNCT05009654Written as L-leucine
As the comparator · 2 — what is tested is compared with Leucine
Codes
What other systems call Leucine · ClinicalTrials.gg INT007728
- MeSH (NLM) D007930LeucineConfirmed NLM, Wikidata
- UNII (FDA) GMW67QNF9CLEUCINEConfirmed FDA, NLM, Wikidata
- RxNorm 6308Confirmed FDA, Wikidata
- Wikidata Q106345666L-leucine zwitterionConfirmed FDA, NLM, Wikidata
- Wikidata Q483745L-leucineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C29599LeucineOne source FDA
- DrugBank DB00149One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D007930 | Leucine | Confirmed NLM, Wikidata |
| UNII (FDA) | GMW67QNF9C | LEUCINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 6308 | — | Confirmed FDA, Wikidata |
| Wikidata | Q106345666 | L-leucine zwitterion | Confirmed FDA, NLM, Wikidata |
| Wikidata | Q483745 | L-leucine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C29599 | Leucine | One source FDA |
| DrugBank | DB00149 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.