Drug
Indomethacin clinical trials
Also written Indocin and Indometacin.
How each study uses Indomethacin is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
Get an email when these change. Save the Indomethacin studies recruiting or about to start — once a week, free: studies that open, close, add sites or post results.
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
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A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Approvals
The first approval found in each region, with its record
- United States
- 10 Jun 1965 · INDOCIN · NDA 016059 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
How studies write it
Studies that test it under each name
Studies by the year they started
91 studies that test it; most in 2020 (8)
| Year | Studies |
|---|---|
| 1993 | 2 |
| 1997 | 2 |
| 1998 | 1 |
| 2000 | 2 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 1 |
| 2005 | 2 |
| 2006 | 1 |
| 2007 | 3 |
| 2008 | 4 |
| 2009 | 3 |
| 2010 | 2 |
| 2011 | 1 |
| 2012 | 5 |
| 2013 | 7 |
| 2014 | 6 |
| 2015 | 2 |
| 2016 | 6 |
| 2017 | 3 |
| 2018 | 4 |
| 2019 | 2 |
| 2020 | 8 |
| 2021 | 3 |
| 2022 | 4 |
| 2023 | 2 |
| 2024 | 3 |
| 2025 | 4 |
| 2026 | 4 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 9 · Other 84
University of Wisconsin, Madison (3) · Radboud University Medical Center (2) · Changhai Hospital (2) · Cairo University (2) · Brock University (2) · Università degli Studi di Brescia (2) · Yale University (2) · Iroko Pharmaceuticals, LLC (2)
Often tested with
Tested in the same studies.
Ibuprofen (6) · Nifedipine (4) · Celecoxib (3) · Acetaminophen (3) · Acetazolamide (2) · Atomoxetine (2) · Isosorbide Dinitrate (2) · Midodrine (2)
Related medicines
As reviewed, each with the page that says it.
- One of Anti-Inflammatory Agents, Non-Steroidal source
- One of NSAIDs source
Coming up
From the study records. Dates are the sponsors’ own estimates and often move.
Reaching primary completion within a year · 4
Studies that test Indomethacin.
- Nov 2026Low-Dose vs Standard-Dose Indomethacin for Preventing Post-ERCP PancreatitisPhase 4 · Changhai Hospital
- Dec 2026Indomethacin vs Diclofenac for Preventing PEPNot applicable · Air Force Military Medical University, China
- Jun 2027Pain Control During Hysterosalpingography: A Three-Arm Randomized TrialPhase 4 · Balikesir University
- Oct 2027Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF PatientsPhase 4 · Western Galilee Hospital-Nahariya
Studies
Open first, then newest update. How each study uses Indomethacin is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 93
- Human Cerebrovascular Blood Flow and Sex Differences in Metabolic SyndromeNot yet recruitingEarly Phase 1University of Wisconsin, MadisonNCT07218653Written as Indomethacin
- Comparative Effectiveness Between Indomethacin and Pancreatic Stenting in the Prevention of Post ERCP PancreatitisRecruitingPhase 3Chinese University of Hong KongNCT03713879Written as Indomethacin
- Pain Control During Hysterosalpingography: A Three-Arm Randomized TrialNot yet recruitingPhase 4Balikesir UniversityNCT07792668Written as Indomethacin 100Mg Suppository
- Indomethacin for Biliary ERCP PatientsNot yet recruitingPhase 4University of California, San FranciscoNCT07661498Written as indomethacin
- Indomethacin vs Diclofenac for Preventing PEPRecruitingNot applicableAir Force Military Medical University, ChinaNCT07071441Written as Indomethacin 100 MG
- Preoperative Indomethacin and Paracetamol for Pain Management During Oocyte Retrieval in IVF PatientsNot yet recruitingPhase 4Western Galilee Hospital-NahariyaNCT07536425Written as Indomethacin 100Mg Suppository
- SHIELD: Sorafenib Hand-foot Syndrome Inhibition With Pre-Emptive Local Delivery of Topical IndomethacinRecruitingPhase 2National Taiwan University HospitalNCT07560566Written as Topical Indomethacin
- Low-Dose vs Standard-Dose Indomethacin for Preventing Post-ERCP PancreatitisRecruitingPhase 4Changhai HospitalNCT07088757Written as standard dose indomethacin
- Single-dose Prophylactic INdomethacin in Extremely Preterm InfantsNot yet recruitingPhase 2University of British ColumbiaNCT06572917Written as Indomethacin
- Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial)RecruitingPhase 4Peking Union Medical College HospitalNCT03547232Written as Indomethacin SR
- Enzalutamide and Indomethacin in Treating Patients With Recurrent or Metastatic Hormone-Resistant Prostate CancerRecruitingPhase 1/2Mamta ParikhNCT02935205Written as Indomethacin
- Randomized Controlled Trial of Rectal Indomethacin Versus Combined Pancreatic Stent Placement and Rectal Indomethacin for Preventing Post-ERCP PancreatitisRecruitingNot applicableMoti Lal Nehru Medical CollegeNCT05857514Written as Rectal Indomethacin
- Vaginal Indomethacin for Preterm LaborNot yet recruitingPhase 2/3Hadassah Medical OrganizationNCT04404686Written as Indomethacin
- LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell HistiocytosisActive, not recruitingPhase 2/3North American Consortium for HistiocytosisNCT02205762Written as INDOMETHACIN
- Treatment of Orthostatic IntoleranceActive, not recruitingPhase 1/2Satish R. RajNCT00262470Written as Indomethacin
- Human Cerebral Blood Flow RegulationCompletedEarly Phase 1University of Wisconsin, MadisonNCT04265053Written as Indomethacin 25 MG/50 MG
- Phase I Platinum Based Chemotherapy Plus IndomethacinCompletedPhase 1UMC UtrechtNCT01719926Written as Indomethacin
- Prophylaxis Against Post-Endoscopic Retrograde Cholangio-Pancreatography Pancreatitis.CompletedPhase 3Hospital General de Chihuahua - Dr. Salvador Zubirán AnchondoNCT07599605Written as Rectal Indometacin
- Rectal Indomethacin vs Intravenous KetorolacCompletedPhase 4David Vitale MDNCT05664074Written as Rectal indomethacin
- Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)CompletedPhase 1Providence Health & ServicesNCT02950259Written as Indomethacin
See all 93 studies that test Indomethacin →
Given beside what is tested · 25 — Indomethacin is usual care or a partner of the new treatment
- Rectal Indomethacin With or Without Papillary Ice Water Irrigation to Prevent Post-ERCP PancreatitisNot yet recruitingNot applicableUnity Health TorontoNCT07826026Written as Rectal Indomethacin
- Short-Stay Aggressive Hydration to Prevent Post-ERCP PancreatitisRecruitingNot applicableWestmead HospitalNCT07776561Written as Rectal Indomethacin
- Indometacin With or Without Aggressive Intravenous Hydration to Prevent Pancreatitis After Pancreatic Extracorporeal Shock Wave LithotripsyRecruitingNot applicableChanghai HospitalNCT07202559Written as Indometacin suppository
- Rectal Indomethacin and Oral Tacrolimus Versus Combination to Prevent Post-ERCP PancreatitisRecruitingPhase 3Johns Hopkins UniversityNCT05252754Written as Rectal Indomethacin
- Azithromycin to Improve Latency in Exam Indicated Cerclage Control TrialRecruitingPhase 4Thomas Jefferson UniversityNCT05132829Written as Cefazolin and indomethacin
- Brain Blood Flow Responses to Stress: Sex DifferencesCompletedPhase 4University of Wisconsin, MadisonNCT06253702Written as Indomethacin
- Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier FunctionCompletedEarly Phase 1Mayo ClinicNCT05538247Written as Indomethacin
- E7 TCR T Cells for Human Papillomavirus-Associated CancersCompletedPhase 1/2National Cancer Institute (NCI)NCT02858310Written as Indomethacin
- T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial CancersTerminatedPhase 1National Cancer Institute (NCI)NCT05035407Written as Indomethacin
- IRX-2 Regimen in Treating Women With Cervical Squamous Intraepithelial Neoplasia 3 or Squamous Vulvar Intraepithelial Neoplasia 3TerminatedPhase 2University of Southern CaliforniaNCT03267680Written as Indomethacin
- IRX-2 Regimen in Patients With Newly Diagnosed Stage II, III, or IVA Squamous Cell Carcinoma of the Oral CavityCompletedPhase 2Brooklyn ImmunoTherapeutics, LLCNCT02609386Written as Indomethacin
- A First Time in Human Study to Evaluate the Safety and Tolerability of GSK4381406 in Healthy ParticipantsWithdrawnPhase 1GlaxoSmithKlineNCT05999708Written as Indomethacin
- Efficacy and Safety Study of Leukocyte Interleukin,Injection (LI) to Treat Cancer of the Oral CavityCompletedPhase 3CEL-SCI CorporationNCT01265849Written as Indomethacin
- A Phase II Neoadjuvant Study of Apalutamide, Abiraterone Acetate, Prednisone, Degarelix and Indomethacin in Men With Localized Prostate Cancer Pre-prostatectomyCompletedPhase 2University of WashingtonNCT02849990Written as Indomethacin
- The Efficacy of Pancreatic Duct Stenting With Rectal Indomethacin in Preventing Post-ERCP PancreatitisCompletedNot applicableFirst People's Hospital of HangzhouNCT03643900Written as rectal indomethacin
- A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck CancerCompletedPhase 2Brooklyn ImmunoTherapeutics, LLCNCT00210470Written as Indomethacin
- 7 cm vs. 5 cm Pancreatic Stents for the Prevention of Post-ERCP Pancreatitis in High-risk PatientsStatus unknownNot applicableAir Force Military Medical University, ChinaNCT04145336Written as Indomethacin
- Performance of 13C Mannitol for in Vivo Measurement of Small Intestinal PermeabilityCompletedPhase 1Mayo ClinicNCT02603822Written as Indomethacin
- Pharmacological Prophylaxis of Post- Endoscopic Retrograde Cholangiopancreatography (ERCP) PancreatitisStatus unknownPhase 4Grigore T. Popa University of Medicine and PharmacyNCT03708458Written as indomethacin suppository
- Pharmacologic Treatment of Congenital Nephrogenic Diabetes InsipidusCompletedNot applicableUniversity of Colorado, DenverNCT00478335Written as indomethacin
Showing 20 of 25.
As the comparator · 13 — what is tested is compared with Indomethacin
- Prophylactic PS Placement to Prevent Pancreatitis After Endoscopic Transpapillary GPC for Cholelithiasis With Concomitant CholedocholithiasisRecruitingNot applicableQilu Hospital of Shandong UniversityNCT07495111Written as rectal indomethacin alone
- Efficacy and Safety of Parecoxib vs. Indomethacin in Preventing Post-ERCP PancreatitisNot yet recruitingPhase 2Shanghai General Hospital, Shanghai Jiao Tong University School of MedicineNCT06623513Written as Indomethacin suppository
- Papillary Epinephrine Injection vs Rectal IndomethacinCompletedPhase 4Duzce UniversityNCT07173179Written as Indomethacin
- Prophylaxis of Post-ERCP Acute PancreatitisCompletedPhase 3Azienda USL Reggio Emilia - IRCCSNCT05381428Written as Indomethacin suppository
- Prevention of Post-ERCP Pancreatitis by Indomethacin Vs DiclofenacTerminatedNot applicableAir Force Military Medical University, ChinaNCT05947461Written as 100mg indomethacin
- Evaluation of Efficacy and Safety of Meloxicam Suppository (15mg Daily) and Tablet (15 mg Daily) Compared to Indomethacin Suppository (50 mg Daily) in Patients With Ankylosing SpondylitisCompletedPhase 3Boehringer IngelheimNCT02183168Written as Indomethacin
- Celebrex In Acute Gouty Arthritis StudyCompletedPhase 3Pfizer's Upjohn has merged with Mylan to form Viatris Inc.NCT00549549Written as Indomethacin
- Acetaminophen vs Indomethacin in Treating hsPDATerminatedPhase 3University of TennesseeNCT03537144Written as Indomethacin
- Evaluate the Safety, Tolerability, & Pharmacokinetics of K-285 Compared With Indomethacin Capsule in Healthy AdultsCompletedPhase 1Kowa Research Institute, Inc.NCT03712241Written as Indomethacin
- The Effect of Dehydration on Intestinal PermeabilityCompletedNot applicableÖrebro University, SwedenNCT03620825Written as Indomethacin
- Apremilast Therapy for Acute Gouty ArthritisWithdrawnPhase 2Dartmouth-Hitchcock Medical CenterNCT00997581Written as indomethacin SR
- COX-2 Inhibitor to Prevent Post-ERCP PancreatitisStatus unknownPhase 4First Affiliated Hospital Xi'an Jiaotong UniversityNCT02964403Written as Indomethacin
- Oral Resveratrol to Prevent Post-ERCP PancreatitisStatus unknownPhase 4First Affiliated Hospital Xi'an Jiaotong UniversityNCT02947932Written as Indomethacin
Codes
What other systems call Indomethacin · ClinicalTrials.gg INT007658
- MeSH (NLM) D007213IndomethacinConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) XXE1CET956INDOMETHACINConfirmed FDA, NLM, Wikidata
- RxNorm 5781Confirmed FDA, Wikidata
- Wikidata Q409231indomethacinConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C576IndomethacinOne source FDA
- DrugBank DB00328One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D007213 | Indomethacin | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | XXE1CET956 | INDOMETHACIN | Confirmed FDA, NLM, Wikidata |
| RxNorm | 5781 | — | Confirmed FDA, Wikidata |
| Wikidata | Q409231 | indomethacin | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C576 | Indomethacin | One source FDA |
| DrugBank | DB00328 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.