Leukomalacia, Periventricular clinical trials
The registry lists 40 studies for Leukomalacia, Periventricular across more than 10 countries. 5 are recruiting or about to start. 6 of them are mainly about Leukomalacia, Periventricular (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-19.
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Who runs them
NICHD Neonatal Research Network (2) · Baylor College of Medicine (2) · Children's Hospital of Fudan University (2) · University College Cork (2) · Sheba Medical Center (1) · Swiss Neonatal Network (1) · The George Washington University Biostatistics Center (1) · Dr Cipto Mangunkusumo General Hospital (1)
What is being tested here
Drugs under test in Leukomalacia, Periventricular studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Mar 2027Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With Diplegia · University of Alberta
Who these studies take
Of the 2 Leukomalacia, Periventricular studies recruiting now, 0 (0%) set no upper age limit and 2 (100%) stop at 75 or younger. 2 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 0 (0%) | 0 (0%) |
| 30 | 0 (0%) | 0 (0%) |
| 40 | 0 (0%) | 0 (0%) |
| 50 | 0 (0%) | 0 (0%) |
| 65 | 0 (0%) | 0 (0%) |
| 75 | 0 (0%) | 0 (0%) |
| 85 | 0 (0%) | 0 (0%) |
Across all 40 studies, recruiting or not: 75% stop at 75 or younger and 73% at 65; 98% take children; 8% are for women only and 0% for men only; 10% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
- Intelligent Physiological Monitoring to Predict Preterm Brain InjuryOct 19, 2026NCT07880431
Studies
Recruiting first, then most recently updated. Showing 40 of 40. search them.
- Intelligent Physiological Monitoring to Predict Preterm Brain InjuryEnrolling by invitationNCT078804311 country
- A Multicenter, International, Prospective and Retrospective, Follow-up Registry to Monitor the Efficacy and Safety of the Occlutech Paravalvular Leak Device (PLD) in Patients With Mitral or Aortic Paravalvular LeaksEnrolling by invitationNCT070374466 countries
- Neonatal White Matter Injury Trial (WRAP)RecruitingNCT07688746Phase 11 country
- Cerebral/ Cortical Visual Impairment: Screening, Identification and Outcome Prediction in NeonatesRecruitingNCT072750211 country
- PUFAs in Preterm InfantsNot yet recruitingNCT06045130
- Spinal Stimulation and Mobility DevicesCompletedNCT05520359Not applicable1 country
- Prediction of Brain Injury in Premature InfantsCompletedNCT028143831 country
- Randomized Controlled Trial of Early Intensive Leg Exercise to Improve Walking in Children With DiplegiaActive, not recruitingNCT03672877Not applicable1 country
- The Role of Cerebral NIRS in Preventing Brain Injury of Very Low Birth Weight Preterm InfantsCompletedNCT06729398Not applicable1 country
- Cell-Based Therapy for White Matter Repair in Periventricular LeukomalaciaWithdrawnNCT06985303Early Phase 1
- A Study to Investigate the Safety and Efficacy of UC-MSCs in Pediatric Patients With Cerebral PalsyCompletedNCT04873752Phase 1/21 country
- Inhaled Nitric Oxide and Neuroprotection in Premature InfantsTerminatedNCT00515281Phase 2/31 country
- Antibiotic "Dysbiosis" in Preterm InfantsCompletedNCT02784821Phase 21 country
- Sonographic QUantification of Venous Circulation In the Preterm BrainCompletedNCT04535375Not applicable1 country
- Evaluation of Long-term Neurodevelopment in Neonatal Encephalopathy by Infant TreadmillWithdrawnNCT03527498Not applicable1 country
- Evaluation of Long-Term Gait Development in Infants With Neonatal Encephalopathy Using Infant TreadmillTerminatedNCT03534466Not applicable1 country
- Randomized Trial of Maternal Progesterone TherapyCompletedNCT02133573Phase 21 country
- Physiological Disturbances Associated With Neonatal Intraventricular HemorrhageTerminatedNCT00665769Not applicable1 country
- Effects of Delayed Cord Clamp and/or Indomethacin on Preterm Infant Brain InjuryCompletedNCT02221219Phase 1/21 country
- Single-session tDCS in Cerebral PalsyCompletedNCT03635775Not applicable1 country
- Management of Hypotension In the Preterm InfantTerminatedNCT01482559Phase 35 countries
- Safety and Efficacy Study of the Draeger Babylog VN500 Device in HFOV Mode in VLBW NeonatesStatus unknownNCT02445040Not applicable1 country
- MISA to NRDS:a Multicenter Study in ChinaCompletedNCT04077333Not applicable1 country
- Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)CompletedNCT00014989Phase 31 country
- Antenatal Phenobarbital to Prevent Neonatal Intracranial HemorrhageCompletedNCT00009620Phase 31 country
- Does Erythropoietin Improve Outcome in Very Preterm Infants?CompletedNCT00413946Phase 21 country
- Effect of Erythropoietin in Premature Infants on White Matter Lesions and Neurodevelopmental OutcomeStatus unknownNCT03110341Phase 31 country
- In Utero Magnesium Sulfate Exposure: Effects on Extremely-Low-Birth-Weight InfantsCompletedNCT012035011 country
- Telerehabilitation of Working Memory in Children With Periventricular Leukomalacia and Bilateral Cerebral PalsyCompletedNCT02342990Not applicable1 country
- Ascorbyl Peroxide Association With Bronchopulmonary DysplasiaCompletedNCT014392951 country
- Premature Infants in Need of Transfusion (PINT)CompletedNCT00182390Phase 33 countries
- Umbilical Cord Blood Proteomic Analysis and Neonatal Brain InjuryCompletedNCT003759081 country
- S100B as a Marker of Brain Injury of Preterm InfantsStatus unknownNCT020825351 country
- High-Dose Erythropoietin in Extremely Premature Infants to Prevent/Attenuate Brain Injury: A Phase II StudyTerminatedNCT00589953Phase 21 country
- Neuroprotection by Magnesium Sulfate Given to Women at Risk of Very Preterm BirthCompletedNCT00120588Phase 41 country
- Probiotics for the Prevention of Premature Birth and Neonatal Related MorbidityTerminatedNCT00303082Phase 31 country
- Recombinant Erythropoietin for Neuroprotection in Very Preterm InfantsStatus unknownNCT00910234Phase 1/21 country
- Optic Discs in Children With Cerebral PalsyCompletedNCT007691971 country
- Liberal Versus Restrictive Transfusion Guidelines for Preterm InfantsCompletedNCT00369005Not applicable
- Magnesium Sulfate to Prevent Brain Injury in Premature InfantsStatus unknownNCT00065949Phase 31 country