Hypnotics and Sedatives: all 2,749 studies that test it

Page 8 of 28. Open to participants first (425), then studies with results posted, then the rest; newest registration first within each.

• A Study of Diazepam After Intranasal and Intravenous Administration to Healthy VolunteersCompletedNCT01364558Phase 1Results posted
• Dexmedetomidine (Precedex®) for Severe Alcohol Withdrawal Syndrome (AWS) and Alcohol Withdrawal Delirium (AWD)TerminatedNCT01362205Phase 4Results posted
• Dexmedetomidine and Propofol in Children With History of Obstructive Sleep ApneaCompletedNCT01344759Phase 4Results posted
• Propofol vs Propofol + Benzo/Opiates in High Risk GroupTerminatedNCT01315158Not applicableResults posted
• A Study of the Effect of LY2216684 on LorazepamCompletedNCT01275144Phase 1Results posted
• Desflurane or Propofol Anesthesia in Elderly Obese Patients Undergoing Total Knee ReplacementCompletedNCT01270620Phase 4Results posted
• A Comparison of Remifentanil and Dexmedetomidine for Craniotomy Perioperative Hemodynamics and Postoperative PainCompletedNCT01269918Not applicableResults posted
• A PK/PD Study of Fospropofol Disodium Compared With Propofol Injectable EmulsionCompletedNCT01260142Phase 4Results posted
• A Trial Of Oral Chloral Hydrate Versus Intranasal Dexmedetomidine For Sedated Abr ExamsCompletedNCT01255904Phase 4Results posted
• Propofol in Obese ChildrenCompletedNCT01242241Phase 3Results posted
• The Effects of Denosumab on the Pharmacokinetics (PK) of MidazolamCompletedNCT01221727Phase 1Results posted
• Total Intravenous Anesthesia (TIVA) vs. Inhaled Anesthesia for Endoscopic Sinus Surgery.TerminatedNCT01214057Not applicableResults posted
• A Tasisulam and Midazolam Drug Interaction Study in Cancer PatientsTerminatedNCT01209832Phase 1Results posted
• Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy VolunteersCompletedNCT01204255Not applicableResults posted
• The Effects of Dexmedetomidine and Propofol on Cerebral Blood Flow and Brain Oxygenation During Deep Brain StimulationCompletedNCT01200433Not applicableResults posted
• Usefulness of Dexmedetomidine on Post-operative Pain Management in Patients With Interstitial CystitisCompletedNCT01195116Phase 4Results posted
• Lusedra (Fospropofol Disodium) for Minimal to Moderate Sedation for Regional Anesthesia Block Prior to Orthopedic SurgeryTerminatedNCT01195103Phase 4Results posted
• Compare Pharmaceutical Economics and Efficacy of Sevoflurane With Low Fresh Gas Flow Balanced Anesthesia, Propofol Target Controlled Infusion Anesthesia and Propofol Induction Sevoflurane Maintenance AnesthesiaCompletedNCT01191476Phase 4Results posted
• Dose Rate Range Finding Study of Propofol for minimal-to Moderate Sedation on Upper & Lower Endoscopic TestsCompletedNCT01189604Phase 2Results posted
• Dexmedetomidine Versus Fentanyl Following Pressure Equalization Tube PlacementCompletedNCT01188551Phase 2/3Results posted
• Pharmacokinetics, Safety and Tolerability of Escalating Rifapentine Doses in Healthy VolunteersCompletedNCT01162486Phase 1Results posted
• Safety, Efficacy and Pharmacokinetic Study of Dexmedetomidine in Pediatrics Ages ≥28 Weeks to ≤44 Weeks Gestational AgeCompletedNCT01159262Phase 2/3Results posted
• Alternative Sedation During BronchoscopyCompletedNCT01158820Phase 4Results posted
• Comparing Safety and Efficacy of Dexmedetomidine and PropofolTerminatedNCT01152021Phase 3Results posted
• Propofol for Pediatric Tracheal Intubation With Deep Anesthesia During Sevoflurane InductionCompletedNCT01150838Phase 4Results posted
• Study To Assess The Effect Of Gabapentin, Diphenhydramine And Morphine On Cold Pain In Healthy Male VolunteersCompletedNCT01119222Phase 1Results posted
• The Effect of Eszopiclone on the Arousal Threshold in Sleep Apnea SyndromeCompletedNCT01102270Early Phase 1Results posted
• Prophylactic Phenobarbital After Neonatal SeizuresTerminatedNCT01089504Phase 4Results posted
• Sedation With Dexmedetomidine During Cardiac CatheterizationTerminatedNCT01072643Phase 2/3Results posted
• Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU)TerminatedNCT01059929Phase 4Results posted
• Dexmedetomidine in Pediatric TonsillectomyCompletedNCT01057381Phase 4Results posted
• A Bioequivalence and Food Effect Study of SEP-190 in Japanese Healthy Subjects (Study SEP 190-102)CompletedNCT01055834Phase 1Results posted
• Sedation in Patients at Risk for Upper Airway CollapseCompletedNCT01045122Not applicableResults posted
• Intraoperative Bleeding During Endoscopic Sinus SurgeryCompletedNCT01014728Not applicableResults posted
• Dexmedetomidine Versus Propofol in Vitreoretinal SurgeryCompletedNCT01001429Phase 4Results posted
• A Pharmacokinetic Study of RO5185426 in Combination With a Drug Cocktail in Patients With Metastatic MelanomaCompletedNCT01001299Phase 1Results posted
• Markers of Liver Apoptosis After Anesthesia With Sevoflurane or PropofolCompletedNCT01000337Not applicableResults posted
• Propofol Versus Ketamine for Moderate Procedural Sedation in the Emergency Department (ED)CompletedNCT00997321Phase 4Results posted
• Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural SedationCompletedNCT00997126Phase 4Results posted
• Pain After Laparoscopic CholecystectomyCompletedNCT00983918Not applicableResults posted
• Analgesic Effect of Peripheral DexmedetomidineCompletedNCT00971178Phase 3Results posted
• Study Evaluating the Effect of Desvenlafaxine on the Pharmacokinetics of MidazolamCompletedNCT00952653Phase 4Results posted
• Adjunct Sedatives in Endoscopic Ultrasound (EUS) and Endoscopic Retrograde Cholangiopancreatography (ERCP) ProceduresCompletedNCT00937924Phase 4Results posted
• Dexmedetomidine as Adjunctive Therapy for Alcohol WithdrawalCompletedNCT00936377Not applicableResults posted
• Effects of Daytime Eszopiclone Administration in Shift WorkersCompletedNCT00900159Not applicableResults posted
• Midazolam Effect in Children Undergoing Voiding Cystourethrogram (VCUG)TerminatedNCT00894465Not applicableResults posted
• Eszopiclone Treatment & Cortisol ResponsivityCompletedNCT00889200Phase 4Results posted
• Study of Sleep-maintenance Activity of 3 Doses of SKP-1041CompletedNCT00878553Phase 2Results posted
• Study Evaluating Safety and Efficacy of Dexmedetomidine (DEX) in Intubated and Mechanically Ventilated Pediatric Intensive Care Unit (PICU) SubjectsCompletedNCT00875550Phase 3Results posted
• Efficacy and Safety of Dexmedetomidine During Non-Invasive Positive Pressure VentilationCompletedNCT00871624Phase 2Results posted
• Dose-Finding Safety Study Evaluating Remimazolam (CNS 7056) in Patients Undergoing Diagnostic Upper GI EndoscopyCompletedNCT00869440Phase 2Results posted
• Use of Dexmedetomidine to Reduce Emergence Delirium Incident in ChildrenCompletedNCT00857727Phase 3Results posted
• Long Term Safety Study of Study Drug (Eszopiclone) in Children and Adolescents With ADHD -Associated InsomniaCompletedNCT00857220Phase 3Results posted
• Safety & Efficacy Study of Study Drug (Eszopiclone) in Children and Adolescents With Attention-deficit/Hyperactivity Disorder - Associated InsomniaCompletedNCT00856973Phase 3Results posted
• Sedation and Pain (The Effect of IV Sedation on Pain Perception)CompletedNCT00853333Not applicableResults posted
• Measures to Lower the Stress Response in Pediatric Cardiac SurgeryCompletedNCT00848393Phase 2Results posted
• Effects of Eszopiclone on Sleep-dependent Learning in SchizophreniaCompletedNCT00833547Not applicableResults posted
• Alprazolam Extended-Release 3mg Tablets Bioequivalence Study Under Non-fasting ConditionsCompletedNCT00830024Phase 1Results posted
• Zaleplon 10mg Capsules Under Fasting ConditionsCompletedNCT00829998Phase 1Results posted
• Zaleplon 10 mg Capsules Under Non-Fasting ConditionsCompletedNCT00829868Phase 1Results posted
• Alprazolam Extended-Release 3mg Tablets Bioequivalence Study Under Fasting ConditionsCompletedNCT00829426Phase 1Results posted
• The Effects of Eszopiclone and Lexapro on Prefrontal Glutamate and GABA in Depression With Anxiety and InsomniaCompletedNCT00826111Phase 4Results posted
• Eszopiclone and Inflammatory Mediators in Patients With Acute Coronary SyndromeCompletedNCT00822679Phase 4Results posted
• Treatment of Insomnia in MigraineursCompletedNCT00812214Phase 4Results posted
• Paramedic Treatment of Prolonged Seizures by Intramuscular Versus Intravenous Anticonvulsant MedicationsCompletedNCT00809146Phase 3Results posted
• Intraoperative Infusion of Precedex to Reduce Length of Stay After Lumbar Spine FusionCompletedNCT00808665Phase 4Results posted
• Efficacy of Aerobic Exercise Added to Alprazolam in Panic Disorder TreatmentCompletedNCT00803400Phase 4Results posted
• Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the ElderlyCompletedNCT00788008Not applicableResults posted
• A Phase III Study of Eszopiclone in Patients With Insomnia (Study SEP 190-150)CompletedNCT00770692Phase 3Results posted
• A Phase II/III Study of SEP-190 (Eszopiclone) in Patients With Primary Insomnia (Study 190-126)CompletedNCT00770510Phase 2/3Results posted
• The Effect of Intravenous Anesthetics on Fear Learning and MemoryCompletedNCT00767767Not applicableResults posted
• Dexmedetomidine Versus Midazolam for Facilitating ExtubationCompletedNCT00744380Not applicableResults posted
• Treatment of Insomnia and Glucose MetabolismCompletedNCT00724282Phase 4Results posted
• Disulfiram Combined With Lorazepam for Alcohol Dependence and Anxiety DisorderCompletedNCT00721526Phase 4Results posted
• Addition of Nitrous Oxide and Its Effects on Depth of AnesthesiaCompletedNCT00717574Not applicableResults posted
• PharmacofMRI (Functional Magnetic Resonance Imaging) of Anxiolytic Medications (Alprazolam)CompletedNCT00703885Phase 4Results posted
• Dexmedetomidine Cardiovascular Safety in Pediatric Burn PatientsCompletedNCT00697788Phase 2Results posted
• Use of a Modified Propofol Emulsion in AdultsCompletedNCT00690495Phase 3Results posted
• Improving Sedation of Children Undergoing Procedures in the Emergency DepartmentCompletedNCT00675909Not applicableResults posted
• Susceptibility of Motor-Evoked Potentials to Varying Targeted Blood Levels of DexmedetomidineCompletedNCT00671931Phase 1Results posted
• Drug Treatment Validation of Functional Magnetic Resonance Imaging in Generalized Anxiety DisorderCompletedNCT00662259Phase 4Results posted
• Dexmedetomidine for Immediate Perioperative Analgesia in Pediatric Patients Undergoing TonsillectomyCompletedNCT00654511Phase 4Results posted
• Dexmedetomidine vs Fentanyl for BMTCompletedNCT00654329Phase 4Results posted
• Pharmacokinetics and Pharmacodynamics of Dexmedetomidine in Pediatrics SubjectsCompletedNCT00652028Phase 2Results posted
• The Effect of Sedation on Eye MovementsCompletedNCT00646646Not applicableResults posted
• Randomized, Controlled, Double Blind Trial of Eszopiclone for Insomnia Associated With SchizophreniaCompletedNCT00645944Not applicableResults posted
• Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)CompletedNCT00641563Not applicableResults posted
• Lumbar Stenosis Outcomes Research (LUSTOR)CompletedNCT00638443Phase 4Results posted
• The Effect on Cognition of Terminating ECT Induced Seizures With PropofolCompletedNCT00616759Not applicableResults posted
• Generalized Anxiety Disorder Proof of Concept Efficacy and Safety Study of SEP-225441 (Eszopiclone) In GAD SubjectsCompletedNCT00616655Phase 2Results posted
• Intravenous Versus Inhalational Anesthesia in Parkinson's DiseaseTerminatedNCT00615472Not applicableResults posted
• GABA Mechanisms Underlying the Vulnerability to Alcohol DependenceCompletedNCT00611767Not applicableResults posted
• Staccato Alprazolam Abuse LiabilityCompletedNCT00603980Phase 1Results posted
• Safety and Efficacy of Two Vaginal Products Versus Placebo in Patients With Vaginal DiscomfortCompletedNCT00590590Phase 2Results posted
• Psychological Influences on Postoperative RecoveryCompletedNCT00581139Phase 2Results posted
• Safety and Efficacy of Oral Midazolam for Perioperative Anxiety Relief of Patients Undergoing Mohs Micrographic SurgeryCompletedNCT00578214Not applicableResults posted
• Understanding Dexmedetomidine in Neonates After Open Heart SurgeryCompletedNCT00576381Phase 1Results posted
• Understanding Dexmedetomidine In Infants Post-Operative From Cardiac SurgeryCompletedNCT00573066Phase 1Results posted
• A Placebo-Controlled Study of a Combination of Metyrapone and Oxazepam in Cocaine AddictionCompletedNCT00567814Not applicableResults posted
• Perioperative Cognitive Function - Dexmedetomidine and Cognitive ReserveCompletedNCT00561678Phase 4Results posted

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