Hypnotics and Sedatives: all 2,749 studies that test it
Page 10 of 28. Open to participants first (425), then studies with results posted, then the rest; newest registration first within each.
- Hemodynamic Effects of Fentanyl Vs Dexmedetomidine in Spine SurgeryCompletedNCT07238101Phase 4
- Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult ParticipantsCompletedNCT07235748Phase 1
- Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and PrednisoloneCompletedNCT07226635Phase 1
- The Effectiveness of Intracuff Dexmedetomidine in Preventing Postoperative Sore Throat Following Prone SurgeryCompletedNCT07202624Phase 2
- Dexmedetomidine vs Ketamine as Adjuvants to Bupivacaine in Transversus Abdominus Plane Block in Inguinal HernioplastyCompletedNCT07194694Phase 3
- Efficacy of Propofol Combination With Either Ketamine, Dexmedetomidine or Midazolam for Sedation During Upper Gastrointestinal Endoscopic ProceduresCompletedNCT07190612Phase 4
- A Study to Learn If the Study Medicine Called PF-08049820 Changes How the Body Processes the Other Study Medicines Called Oral Contraceptives, Midazolam, and Dabigatran in Healthy Adult Female ParticipantsCompletedNCT07190430Phase 1
- Effect of Discontinuing Propofol After Cecal Intubation on Patient's Psychomotor Recovery Following ColonoscopyActive, not recruitingNCT07168135Not applicable
- Propofol Dose-Finding for Colonoscope Insertion in Adult PatientsCompletedNCT07166640Not applicable
- Dexmedetomidine vs Propofol in High-Risk ERCP PatientsCompletedNCT07166614Not applicable
- Propofol Dose-Finding for Colonoscope Insertion in Geriatric PatientsCompletedNCT07162805Not applicable
- Dexmedetomidine Nasal Spray for the Treatment of Panic Attacks in AdultsCompletedNCT07162649Not applicable
- Oral vs IV Sedation for Cataract Surgery in Older AdultsCompletedNCT07154147Phase 4
- Sedation With Dexmedetomidine-esketamine Combination and Delirium in ICU PatientsCompletedNCT07151716Phase 4
- Role of Pericapsular Nerve Block Using Dexmedetomidine and Bupivacaine in Improving the Outcome of Patients Undergoing Hip Surgery Under Spinal AnesthesiaCompletedNCT07149168Phase 1
- Dexmedetomidine Dose-Dependent on Lung Function and AQP1 in One-Lung Ventilation SurgeryCompletedNCT07145814Not applicable
- ED50 of Dexmedetomidine as an Adjuvant to 0.5% Hyperbaric Bupivacaine 12.5 mg for Spinal Anesthesia in Hip and Knee Surgery: An Up-and-Down Method ApproachCompletedNCT07144215Not applicable
- COMPARISON OF BUPIVACAINE WITH AND WITHOUT DEXMEDETOMIDINE IN CAUDAL BLOCK AMONG CHILDREN UNDERGOING INGUINAL HERNIOTOMYCompletedNCT07140627Phase 1
- Intravenous Regional Analgesia of DexmedetomidineActive, not recruitingNCT07131579Not applicable
- Postoperative Pain Relief in Children: Comparing Caudal Bupivacaine Alone Versus Bupivacaine With Dexmedetomidine for Infra-Umbilical Surgeries Under General AnesthesiaCompletedNCT07121764Phase 4
- A Study to Evaluate the Effects of KarXT on the Drug Levels of Midazolam, Fexofenadine, and DigoxinCompletedNCT07118215Phase 1
- Assessment of Acute Psychomotor Agitation Measures Associated With Schizophrenia and Bipolar DisorderCompletedNCT07116694Phase 2
- Total Intravenous Anesthesia in Patients Undergoing CraniotomyActive, not recruitingNCT07105618Not applicable
- Efficacy of Non-weight Based, Low Dose Dex-Dex Adjuncts in Prolonging Peripheral Nerve BlocksActive, not recruitingNCT07099222Phase 1/2
- The Effects of Dexmedetomidine and Remifentanil on Kidney Injury After Muscle Compression Injury in RatsCompletedNCT07094165Not applicable
- Varied Remimazolam Dosages for Pediatric EndoscopyCompletedNCT07083440Not applicable
- Respiratory Depression of Remimazolam vs. Propofol for Monitored Anesthesia CareCompletedNCT07076628Phase 4
- Impact of Adding Dexmedetomidine as an Adjuvant to The Local Anesthetic in Quadratus Lumborum Block in Patient Undergoing Caesarean SectionCompletedNCT07072650Phase 1
- Intranasal Dexmedetomidine, Ketamine or Midazolam for Anxiety and Respiratory Complications in ChildrenCompletedNCT07072117Not applicable
- Adding Dexmedetomidine to Mannitol to Attenuate the Increase of Intracranial PressureCompletedNCT07064720Phase 2/3
- Dexmedetomidine as an Additive for (Ipack)Block in Knee SurgeryCompletedNCT07058493Not applicable
- Effect of Different Drugs on Emergency Delirium in Preschool Age PatientActive, not recruitingNCT07057193Not applicable
- Efficacy of Nebulized Dexmedetomidine on Blunting Hemodynamic Changes During Intubation and Pneumoperitoneum in Morbid Obese Patients During Laparoscopic Bariatric SurgeryCompletedNCT07054138Not applicable
- Effect of Different Doses Of Intrathecal Dexmedetomidine In Combination With Bupivacaine On Spinal AnesthesiaCompletedNCT07051512Phase 1
- Dexmedetomidine Versus Ketamine on Laryngeal MicrosurgeryCompletedNCT07048873Not applicable
- Effects Of Anaesthesia on Intraocular Pressure in Robotic Prostate SurgeryCompletedNCT07033442Not applicable
- A Study to Assess the Time to Onset of Action of Staccato Alprazolam Versus Midazolam and Diazepam in Healthy ParticipantsCompletedNCT07020988Phase 1
- Morphine and Dexmedetomidine as Adjuvants to Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Open Subcostal Renal SurgeriesCompletedNCT07012590Not applicable
- Analgesic and Sedative Effect of Fentanyl Versus Dexmedetomidine Infusion in Post-Operative Mechanically Ventilated Children After Open Abdominal SurgeriesCompletedNCT06994273Not applicable
- Effect of Dexmedetomidine on Microsurgery Reconstruction in Cancer PatientCompletedNCT06993740Not applicable
- Effectiveness of Intranasal Dexmedetomidine Premedication in Child IntubationCompletedNCT06991647Phase 3
- A Drug-drug Interaction Study to Investigate the Pharmacokinetic Interactions Between CKD-508, Midazolam, and Rosuvastatin in Healthy Adult Male ParticipantsCompletedNCT06979973Phase 1
- Efficacy of Intraoperative Magnesium Sulphate vs Dexmedetomidine on Emergence Agitation in Pediatric PatientsCompletedNCT06977425Not applicable
- Infusion of Dexmedetomidine Versus Lidocaine in Management of Acute Postoperative Pain After Modified Radical MastectomyCompletedNCT06974656Not applicable
- Intraoperative Midazolam on Delirium Outcome of Elderly PatientsCompletedNCT06963112Phase 1
- Effect of Dexmedetomidine on Hemodynamics in Cardiac SurgeryCompletedNCT06958913Not applicable
- Effect of Dexmedetomidine on Acute Kidney Injury After Ascending Aortic SurgeriesActive, not recruitingNCT06958367Phase 1
- Dexmedetomidine as an Adjuvant to Bupivacaine in Scalp Block vs Bupivacaine Alone for Hemodynamics Stability in CraniotomyCompletedNCT06951256Not applicable
- Study of BLU-808 in Healthy Adult ParticipantsCompletedNCT06948032Phase 1
- Dexmedetomidine Versus Ketamine-midazolam Sedation in Awake Fiberoptic Intubation in Suspected Difficult AirwayCompletedNCT06946212Phase 4
- Using Lidocaine or Dexmedetomidine to Help Control Blood Pressure Spikes From a Tourniquet During Knee SurgeryCompletedNCT06936410Phase 2
- Fentanyl Versus Midazolam as an Adjunct to Spinal AnesthesiaActive, not recruitingNCT06917898Phase 1
- Effect of Intraarticular Ozone, Prolotherapy or Dexmedetomidine in Pain Limitation in Knee OsteoarthritisCompletedNCT06909305Not applicable
- Dexmedetomidine Enhancing the Recovery After Cardiac SurgeryCompletedNCT06907277Not applicable
- Effect of Dexmedetomidine and Total Intravenous Anesthesia on Endothelial Damage-Related BiomarkersCompletedNCT06897696Phase 4
- Efficacy of Oral Midazolam for Sedation and Amnesia in Preschool Children Undergoing Dental ProceduresCompletedNCT06887712Phase 4
- Optimizing Patient-centred Outcomes Using Opioid Minimization Strategies: The OPUS Anesthesia Pilot TrialActive, not recruitingNCT06884540Not applicable
- Comparison of Oral Dexmedetomidine, Ketamine Versus Midazolam for Premedication in Children Undergoing Injuinal SurgeriesCompletedNCT06879496Not applicable
- Dexmedetomidine Versus Magnesium Sulfate as Adjuvants to Intraperitoneal Bupivacaine for Postoperative Analgesia After Elective Laparoscopic CholecystectomyCompletedNCT06879288Not applicable
- A Study of the Correlation Between the Debilitating State of the Elderly and Propofol SensitivityCompletedNCT06870357Early Phase 1
- Comparison of Two Intravenous Drug Combinations for Ambulatory Oral & Maxillofacial SurgeryCompletedNCT06867068Phase 1
- Dexmedetomidine Infusion in Either Total Intravenous Anesthesia or Inhalational Anesthesia to Improve Surgical Field Visibility in Endoscopic Sinus SurgeryCompletedNCT06866145Phase 4
- Dexmedetomidine vs Tramadol for Anxiety, Pain, and Hemodynamics in HemorrhoidectomyCompletedNCT06860100Not applicable
- Lidocaine and Dexmedetomidine Infusions for Intraoperative Bleeding in Functional Endoscopic Sinus SurgeryCompletedNCT06848764Not applicable
- Lidocaine and Dexmedetomidine Infusion and Their Combination on Perioperative Pain in Patients Undergoing Video-Assisted Thoracoscopic SurgeryCompletedNCT06837519Not applicable
- Sevoflurane and Dexmedetomidine's Contrasting Renal Impacts After Non-Cardiac SurgeryCompletedNCT06835010Not applicable
- Efficacy of Propofol-Ketamine and Sevoflurane in Children Undergoing Magnetic Resonance ImagingCompletedNCT06832683Not applicable
- A Research Study of the Effect of Etavopivat on Other Drugs in Healthy ParticipantsCompletedNCT06813924Phase 1
- Postoperative Cognitive Dysfunction in Transsphenoidal Pituitary SurgeriesCompletedNCT06793150Phase 4
- Dexmedetomidine for ESPB in Pain Management After Pediatric Idiopathic Scoliosis SurgeryCompletedNCT06789016Phase 4
- Comparative Study of Fentanyl vs Dexmedetomidine as Adjuvants to Intrathecal Bupivacaine in Cesarean SectionCompletedNCT06785285Not applicable
- Combination of Remimazolam and Propofol During Drug-induced Sleep EndoscopyActive, not recruitingNCT06784479Phase 4
- Comparison of Safety and Efficacy for Different Sedation Regimens During ColonoscopyCompletedNCT06763705Phase 4
- Amobarbital and Cardiopulmonary BypassCompletedNCT06757868Not applicable
- DISE in Pediatric Sleep Disordered BreathingWithdrawnNCT06756971Phase 2/3
- Adding Magnesium Sulfate or Dexmedetomidine to Bupivacaine in Oblique Subcostal Tap Block for Laparoscopic Cholecystectomy: A Randomized Double -Blind Controlled StudyCompletedNCT06743919Phase 4
- Pro-Epileptic Effects of IV KetamineCompletedNCT06741930Phase 4
- Pre-operative Intra-nasal Dexmedetomidine or Insulin for Prevention of Early Post-operative Cognitive Dysfunction in Patients Undergoing Elective Coronary Artery Bypass Graft.CompletedNCT06741566Early Phase 1
- Serratus Anterior Plane Block Versus Erector Spinae Plane Block With Dexmedetomidine Added to Bupivacaine for Ultrasound-Guided Pain Management After MastectomyCompletedNCT06737458Not applicable
- Clinical Study of Fospropofol Disodium for Injection in the Painless Endoscopic Diagnosis and TreatmentCompletedNCT06732427Not applicable
- Role of Intravenous Dexmedetomidine in Reducing Shivering After Shivering Cesarean Section Due to Spinal AnesthesiaCompletedNCT06711913Phase 2
- Dexmedetomidine for Improved Pain Relief and Recovery in Spine SurgeryCompletedNCT06685081Not applicable
- Dexmedetomidine as an Adjuvant in External Oblique Intercostal Plane Block for Post Thoracotomy PainCompletedNCT06684535Not applicable
- Comparison of Remimazolam and Etomidate As Induction Agents for Electroconvulsive TreatmentCompletedNCT06664138Phase 4
- Perioperative Pain Management for Lumbar Spine SurgeryCompletedNCT06662318Not applicable
- Dexmedetomidine on Brain Injury PatientsCompletedNCT06661980Not applicable
- The Effects of Dexmedetomidine on Postoperative Cognitive Function in Open Heart SurgeryCompletedNCT06655025Not applicable
- Effect of Intravenous or Intrathecal Dexmedetomidine on Bupivacaine Spinal Block in Lower Abdominal SurgeryCompletedNCT06654531Phase 2/3
- Nerve Block Vs Sedation Infusion for Awake Fiberoptic Intubation.CompletedNCT06651905Not applicable
- Study of How Mitapivat Affects Midazolam Blood Levels in Healthy ParticipantsCompletedNCT06648824Phase 1
- Sphenopalatine Block vs Dexmedetomidine Infusion in Trans Nasal Endoscopic Pituitary SurgeryActive, not recruitingNCT06639659Not applicable
- Effect of Dexmedetomidine on Gastric Emptying, Assessed by Ultrasound in Laparoscopic CholecystectomyCompletedNCT06634524Not applicable
- A Study Evaluating the Potential of BMS-984923 to Alter the Systemic Exposure of Three Orally Administered Probe SubstratesActive, not recruitingNCT06632990Phase 1
- Effect of Addition of Dexmedetomidine or Ketamine to Intravenous Infusion of Lidocaine on Proinflammatory Cytokines in Pelvi-abdominal Cancer Surgeries.CompletedNCT06631625Phase 1
- Effect of Propofol and Sevoflurane Anesthesia on HSP70 Expression in Tumor CellsActive, not recruitingNCT06626711Early Phase 1
- Dexmedetomidine in Reducing Postoperative Delirium in Cardiac Surgery PatientsCompletedNCT06619912Phase 3
- Dexmedetomidine Dosage for Postoperative Delirium and Cognitive Function in Elderly TKA PatientsCompletedNCT06614881Not applicable
- Nebulized Dexmedetomidine or Lidocaine for Treatment of Post Dural Puncture Headache in Parturients Undergoing Elective Cesarean Section Under Spinal AnesthesiaCompletedNCT06607861Early Phase 1
- A Comparison Between Oral Melatonin With Nasal Sevoflurane Versus Oral Chloral Hydrate With Nasal Sevoflurane in Sedation of Children Undergoing Brain MRICompletedNCT06606899Not applicable
- Tranexamic Acid Versus Dexmedetomidine for Improving Surgical Field Quality During Spine SurgeriesCompletedNCT06587620Not applicable