Hypnotics and Sedatives: all 2,749 studies that test it

Page 6 of 28. Open to participants first (425), then studies with results posted, then the rest; newest registration first within each.

• Alpha 2 Agonists for Sedation to Produce Better Outcomes From Critical Illness (A2B Trial)CompletedNCT03653832Phase 3Results posted
• Narcotic Free TIVA and Incidence of Unacceptable Movements Under Anesthesia During ACDF SurgeryCompletedNCT03643796Phase 4Results posted
• Effect of Tepotinib on PK of CYP3A Substrate MidazolamCompletedNCT03628339Phase 1Results posted
• Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence IntubationCompletedNCT03545503Phase 4Results posted
• Opioid-Free Shoulder ArthroplastyCompletedNCT03540030Phase 4Results posted
• Dexmedetomidine for Sedation of Endobronchial Ultrasound-guided Transbronchial Needle AspirationCompletedNCT03521505Phase 4Results posted
• Dexmedetomidine and Propofol for Pediatric MRI SedationCompletedNCT03513757Phase 4Results posted
• A Fixed-Sequence, Drug-Drug Interaction Study Between Multiple Oral Doses of Inarigivir Soproxil and a Single Oral Dose of Midazolam in Healthy SubjectsCompletedNCT03493698Phase 1Results posted
• Zaleplon in HIV Patients With DepressionCompletedNCT03489304Phase 2Results posted
• Comparison of Intra-articular Dexmedetomidine and Magnesium in Postoperative PainCompletedNCT03479216Phase 4Results posted
• Inpatient, Dose-Ranging Study of Staccato Alprazolam in Epilepsy With Predictable Seizure PatternCompletedNCT03478982Phase 2Results posted
• Opiates and Benzodiazepines on DrivingCompletedNCT03447353Phase 4Results posted
• Designing Optimal Prevention and Management of Postoperative Nausea and Emesis for Patients Undergoing Laparoscopic Sleeve GastrectomyCompletedNCT03435003Phase 4Results posted
• A Phase 1 Drug-Drug Interaction Study Between Brigatinib and the CYP3A Substrate, Midazolam, in Participants With ALK-Positive or ROS1-Positive Solid TumorsCompletedNCT03420742Phase 1Results posted
• Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart DiseaseTerminatedNCT03417999Phase 1Results posted
• Peripheral Nerve Blocks for Above-the-knee AmputationsCompletedNCT03404180Phase 4Results posted
• The Effects of Dexmedetomidine Dose on Motor Evoked PotentialsTerminatedNCT03378973Phase 4Results posted
• A Study to Evaluate Efficacy, Safety, and Tolerability of Alemtuzumab in Pediatric Patients With RRMS With Disease Activity on Prior DMTTerminatedNCT03368664Phase 3Results posted
• Neuroimaging of Anesthetic Modulation of Human ConsciousnessCompletedNCT03361605Phase 4Results posted
• Patient-controlled Sedation With Propofol Versus Combined Sedation During BronchoscopyCompletedNCT03357393Not applicableResults posted
• Effectiveness of BBT-I and Zopiclone for Chronic InsomniaCompletedNCT03339583Phase 2Results posted
• Open-label Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Children With Status Epilepticus (Convulsive) in a Healthcare Setting in JapanCompletedNCT03336645Phase 3Results posted
• Study of Midazolam Hydrochloride Oromucosal Solution (MHOS/SHP615) in Pediatric Patients With Status Epilepticus (Convulsive) in the Community SettingCompletedNCT03336450Phase 3Results posted
• Study on the Effects of Intravenous Dexmedetomidine on Pain in Patients Undergoing Elective Spinal SurgeryCompletedNCT03325972Phase 4Results posted
• This Study in Healthy Men Tests How Different Doses of BI 705564 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 705564 Affects the Way the Body Breaks Down MidazolamCompletedNCT03325712Phase 1Results posted
• Effects of Dexmedetomidine on Delirium Duration of Non-intubated ICU Patients (4D Trial)CompletedNCT03317067Phase 3Results posted
• Pharmacokinetics of Midazolam, Dabigatran, Pitavastatin, Atorvastatin, and Rosuvastatin in Participants With Renal Insufficiency in the Presence and Absence of Rifampin (MK-0000-386)CompletedNCT03311841Phase 1Results posted
• Sedative-Anxiolytic Effects on Simulated Driving PerformanceCompletedNCT03297944Phase 4Results posted
• UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness StudyCompletedNCT03284307Phase 4Results posted
• Deep Brain Stimulation (DBS) SedationTerminatedNCT03283150Phase 4Results posted
• A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous SedationCompletedNCT03255824Phase 4Results posted
• Oral Versus Intravenous Sedation for Ocular ProceduresCompletedNCT03246724Phase 4Results posted
• Oral Sedation During Cervical Dilator PlacementCompletedNCT03202550Phase 4Results posted
• Propofol and Dexmedetomidine Versus a Propofol Only Regimen for Sedation During ColonoscopyCompletedNCT03139279Phase 4Results posted
• Effect of Dexmedetomidine Combined With Low-dose Nalmefene on Preventing Remifentanil-induced Postoperative HyperalgesiaCompletedNCT03096730Not applicableResults posted
• Treatment of Adolescent Antimuscarinic (Anticholinergic) ToxidromeCompletedNCT03090620Phase 4Results posted
• Comparative Study of Nonintubated Uniport Thoracoscopic Surgery Using Thoracic Paravertebral Nerve Block Versus Intercostal Nerve Block for Peripheral Solitary Pulmonary Nodule PatientsCompletedNCT03086213Not applicableResults posted
• A Comparison of Intranasal Midazolam and Nitrous Oxide (N2O) Minimal Sedation for Minor Procedures in a Pediatric Emergency DepartmentCompletedNCT03085563Phase 4Results posted
• Dexmedetomidine Versus Morphine and Midazolam in Prevention and Treatment of Delirium After Adult Cardiac SurgeryCompletedNCT03078946Phase 4Results posted
• Music vs Midazolam During Preop Nerve Block PlacementCompletedNCT03069677Phase 3Results posted
• Intravenous Dexmedetomidine for Cesarean SectionCompletedNCT03065530Phase 4Results posted
• The Effect of Dexmedetomidine Infusion on Post-operative Cognitive Function and Oxidative Stress in Cardiac SurgeryCompletedNCT03054857Phase 4Results posted
• PREMIX vs PREMED Intranasal Lidocaine and MidazolamCompletedNCT03054844Phase 2Results posted
• Anaesthesia for Laparoscopic Sleeve GastrectomyCompletedNCT03029715Not applicableResults posted
• Safety and Efficacy of Isatuximab in Lymphoblastic LeukemiaTerminatedNCT02999633Phase 2Results posted
• Conscious Sedation for Epilepsy SurgeryCompletedNCT02988050Not applicableResults posted
• A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected ParticipantsCompletedNCT02952924Phase 1Results posted
• The Synergistic Effect of Dexmedetomidine on Propofol for Sedation for Pediatric EndoscopyCompletedNCT02952222Phase 4Results posted
• Patient Satisfaction With Propofol for Out Patient ColonoscopyCompletedNCT02937506Phase 4Results posted
• Pain, Agitation and Delirium (PAD) Protocol in the Duke CICUTerminatedNCT02903407Phase 4Results posted
• Dexmedetomidine to Treat Bariatric Surgery-associated PainCompletedNCT02880540Phase 3Results posted
• MIdazolam Versus MOrphine in Acute Pulmonary Edema (MIMO Trial)TerminatedNCT02856698Phase 4Results posted
• Minimizing ICU Neurological Dysfunction With Dexmedetomidine-induced SleepCompletedNCT02856594Phase 2/3Results posted
• Non-anesthesiologist-administered Propofol During the Flexible BronchoscopyCompletedNCT02820051Not applicableResults posted
• Self-management of Sedative Therapy by Ventilated PatientsCompletedNCT02819141Phase 2/3Results posted
• Repurposing Dexmedetomidine as an Orally Administered Sleep TherapeuticCompletedNCT02818569Phase 1/2Results posted
• Study of DA-9501 In Pediatric Subjects In The Intensive Care UnitCompletedNCT02757625Phase 3Results posted
• Multimodal Analgesia in Cardiac Surgery (Pilot Study)TerminatedNCT02734940Phase 4Results posted
• Repeat-Dose Pharmacokinetics Study of NRL-1 in Epilepsy SubjectsCompletedNCT02724423Phase 1Results posted
• Repeat Dose Safety Study of NRL-1 in Epilepsy SubjectsCompletedNCT02721069Phase 3Results posted
• Treg Therapy in Subclinical Inflammation in Kidney TransplantationCompletedNCT02711826Phase 1/2Results posted
• Comparison of Propofol and Sevoflurane as a Primary Anesthetic for Cardiac Ablation of Atrial Fibrillation.CompletedNCT02697448Not applicableResults posted
• A Study of Abemaciclib in Participants With Cancer That is Advanced or Has Spread to Another Part(s) of the BodyCompletedNCT02688088Phase 1Results posted
• Phase 1 Study to Determine the Effect of Lenvatinib (E7080) on the Pharmacokinetics of Midazolam in Subjects With Advanced Solid TumorsCompletedNCT02686164Phase 1Results posted
• Nasal Versus Oral Midazolam Sedation in Routine Pediatric Dental CareCompletedNCT02679781Not applicableResults posted
• Anesthetic Techniques in EP PatientsTerminatedNCT02664922Phase 4Results posted
• A Policy Relevant US Trauma Care System Pragmatic Trial for PTSD and ComorbidityCompletedNCT02655354Not applicableResults posted
• the Analgesic Duration of Dexmedetomidine Compared to Dexamethasone as Adjuncts to Single Shot Interscalene BlockCompletedNCT02653144Phase 4Results posted
• Diazepam Use With Standard Management for Acute Low Back PainCompletedNCT02646124Phase 2/3Results posted
• Safety and Efficacy of Using SightSaver Visual Evoked Potential (VEP) for VEP Monitoring in Prone Spine SurgeryCompletedNCT02643615Not applicableResults posted
• Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical TrialCompletedNCT02643381Phase 4Results posted
• Recovery Profile Comparison Between Remifentanil-propofol or Desflurane Anesthesia Monitored With Bispectral Index.CompletedNCT02631525Phase 4Results posted
• Cognitive Functions After TIVA With DexmedetomidineCompletedNCT02631135Phase 4Results posted
• Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) ProphylaxisCompletedNCT02625181Not applicableResults posted
• Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBsCompletedNCT02624050Not applicableResults posted
• A Comparative Study of Intrathecal Magnesium Sulphate & Midazolam With Epidural Ropivacaine for Caesarean PatientsCompletedNCT02619799Phase 2/3Results posted
• Intranasal Midazolam for Treatment of Anxiety in Children Undergoing Suturing in the Pediatric Emergency DepartmentCompletedNCT02618772Phase 4Results posted
• Influence of Dexmedetomidine and Lidocaine on Opioid Consumption in Laparoscopic Intestine ResectionCompletedNCT02616523Phase 4Results posted
• Evaluation of Dexmedetomidine on Post-operative Narcotic Requirements and Pain Scores in Bariatric PatientsCompletedNCT02604940Phase 4Results posted
• Ketamine Infusion for Adolescent Depression and AnxietyCompletedNCT02579928Phase 4Results posted
• Total Intravenous Anesthesia in Sinus SurgeryCompletedNCT02578862Phase 4Results posted
• Evaluation of Diphenhydramine Hydrochloride Effects in Subjects With Occasional SleeplessnessCompletedNCT02578186Phase 4Results posted
• The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal DysfunctionCompletedNCT02554253Phase 2Results posted
• Dexmedetomidine or Dexmedetomidine Combined With Dexamethasone on Postoperative Nausea and Vomiting in Breast CancerCompletedNCT02550795Not applicableResults posted
• Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac SurgeryCompletedNCT02546765Phase 4Results posted
• Influence of Anesthetic Technique on Acute and Chronic Neuropathic PainCompletedNCT02527083Phase 4Results posted
• Memory Modulation by Pain During AnesthesiaCompletedNCT02515890Phase 1Results posted
• Isoflurane-induced Neuroinflammation in Children With HydrocephalusTerminatedNCT02512809Phase 3Results posted
• Low-dose Propofol for the Treatment of Severe Refractory Migraine Headache in the Emergency DepartmentTerminatedNCT02492295Not applicableResults posted
• Stress Response and Neurodevelopmental Outcome After Cardiac Surgery Utilizing CPB in Children: A Prospective, Double Blinded and Randomized StudyCompletedNCT02492269Phase 2Results posted
• The Effect of Different Sedation Regimes on Cognitive Function in Lower Gastrointestinal System EndoscopyCompletedNCT02486328Phase 4Results posted
• Low- Dose Propofol Infusion as an Abortive Treatment for Migraine Headaches in Pediatric PatientsCompletedNCT02485418Not applicableResults posted
• Bioavailability, Safety and Tolerability of Diazepam Nasal Spray Versus Diazepam Rectal Gel (Diastat®)TerminatedNCT02474407Phase 2Results posted
• Comparative Study of Ropivacaine and Ropivacaine With Dexmeditomedine in TAP BlocksCompletedNCT02472522Not applicableResults posted
• Dexmedetomidine vs Propofol TIVA (Total Intravenous Anesthesia) and Interscalene BlockCompletedNCT02469961Phase 4Results posted
• Safety and Efficacy of Chronic Hypnotic Use 2CompletedNCT02456532Phase 4Results posted
• Sedatives' Effects on Neurological Function in Patients With Eloquent Area GliomaCompletedNCT02439164Not applicableResults posted
• Inducibility and Stability of Ventricular Tachycardia Inpatients Undergoing VT Ablation Under General AnesthesiaCompletedNCT02419547Not applicableResults posted
• Adjunctive Nitrous Oxide During Emergency Department Propofol Sedation in AdultsCompletedNCT02410707Not applicableResults posted
• Patient-Controlled Anxiolysis With Dexmedetomidine (PCA-DEX) for Burn-care Dressing ChangesCompletedNCT02409810Phase 1/2Results posted

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