Hypnotics and Sedatives: all 2,749 studies that test it
Page 1 of 28. Open to participants first (425), then studies with results posted, then the rest; newest registration first within each.
- Effects of Ciprofol on Perioperative Neurocognitive Function in Elderly Patients Undergoing Daytime SurgeryEnrolling by invitationNCT07895407Phase 4
- Dexmedetomidine as an Adjuvant to Greater Auricular Nerve Block in Middle Ear SurgeriesRecruitingNCT07878533Phase 2
- Dexmedetomidine Use for Greater Occipital Nerve Block in Pediatric Posterior Fossa Tumor Surgery.RecruitingNCT07878156Phase 3
- Conscious Sedation Versus General Anesthesia for Pulsed Field Ablation in Paroxysmal Atrial FibrillationRecruitingNCT07877519Not applicable
- Comparative Evaluation of Intranasal Atomized Midazalom Combined With Nitrous Oxide Versus Nitrous Oxide MonotherapyNot yet recruitingNCT07876024Not applicable
- Ketadex Versus Ketofol for Adult Procedural Sedation in the Emergency Department.Not yet recruitingNCT07874919Phase 4
- Effect of Ketamine-Propofol Total Intravenous Anesthesia Versus Sevoflurane-Based Anesthesia on Postoperative Vomiting in Children Undergoing Strabismus SurgeryNot yet recruitingNCT07871292Phase 4
- A Study of Single and Multiple Doses of LY5625573 in Healthy Participants, Including Japanese and Chinese Populations, and Participants With Inflammation (High C-Reactive Protein)Not yet recruitingNCT07867340Phase 1
- Opioid-Free Versus Opioid-Based Anesthesia in Thyroid SurgeryRecruitingNCT07864155Not applicable
- A Study to Assess the Potential CYP3A Induction Effect of Brensocatib on the Pharmacokinetics (PK) of Midazolam in Healthy ParticipantsNot yet recruitingNCT07859007Phase 1
- Effect of Preoperative Intranasal Dexmedetomidine on Incidence of Intraoperative Shivering in Patients Undergoing Cesarean Section Under Spinal AnesthesiaNot yet recruitingNCT07855536Phase 4
- Efficacy of Intravenous Midazolam-Ketamine Combination Versus Placebo for Prevention of Post-Spinal Shivering in Elective Cesarean SectionNot yet recruitingNCT07855523Phase 4
- Effect of a Low-Dose Ketamine-Dexmedetomidine-Based Opioid-Sparing Anesthesia Protocol on Postoperative Quality of Recovery After Percutaneous NephrolithotomyNot yet recruitingNCT07855068Phase 4
- Effect of Intravenous Versus Caudal Dexmedetomidine on Perfusion Index and Hemodynamic Responses in Children Undergoing Infraumbilical SurgeryNot yet recruitingNCT07852039Phase 4
- Intranasal Dexmedetomidine and Perioperative Myocardial Injury in Patients Having Percutaneous Coronary InterventionsNot yet recruitingNCT07847580Not applicable
- Safety and Efficacy of Dexamethasone Versus Dexmedetomidine as Adjuvants in PENG Block in Hip Surgeries for Postoperative Pain ManagementNot yet recruitingNCT07847047Phase 3
- Esmolol Versus Dexmedetomidine for Opioid-sparing in Laparoscopic Gynecological SurgeryRecruitingNCT07846722Not applicable
- Ultrasound-Guided Ilioinguinal-Iliohypogastric Nerve Block Following Spinal Anesthesia Comparing Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Unilateral Inguinal Hernia RepairNot yet recruitingNCT07837492Phase 4
- Brain Activity and Changes in Consciousness During General AnesthesiaNot yet recruitingNCT07836205Phase 4
- Demedetomidine and Remifentanil in Electroconvulsive Therapy (ECT)RecruitingNCT07824817Phase 4
- Dexmedetomidine Versus Lidocaine for Optic Nerve Sheath Diameter During Craniotomy IntubationNot yet recruitingNCT07820540Phase 4
- Effects of Remimazolam on Postoperative Cognitive Dysfunction and Neuroinflammatory Biomarkers in Patients Undergoing Aortic Arch SurgeryNot yet recruitingNCT07816068Phase 4
- Intrathecal Dexmedetomidine and Postoperative Delirium in Elderly Hip Fracture SurgeryNot yet recruitingNCT07810556Phase 2/3
- Impact of Dexmedetomidine Versus Propofol on Intracranial Pressure in Adult Traumatic Brain Injury Patients: Randomized Controlled Double-Blind TrialNot yet recruitingNCT07807579Phase 4
- This Study Aims to Determine Whether Lower Doses (4 µg) of Intrathecal Dexmedetomidine Can Provide Comparable Analgesic Benefits While Minimizing Adverse Hemodynamic Effects in Patients Encountered in Our Setup( Shifa International Hospital Islamabad).Enrolling by invitationNCT07807020Phase 1/2
- Effect of Remimazolam Versus Propofol Total Intravenous Anesthesia on Intraoperative Hemodynamic Stability in Patients Undergoing Thoracic or Abdominal Endovascular Aortic RepairNot yet recruitingNCT07806006Phase 4
- Comparing the Efficacy of Propofol and Dexmedetomidine in Prevention of Emergence Agitation After Sevoflurane Anesthesia in ChildrenRecruitingNCT07799311Phase 4
- Effects of Fospropofol Disodium TIVA and IVIH on Surgical Field Quality in Adult ESSRecruitingNCT07788157Not applicable
- Intraoperative Targeted Versus Liberal Blood Pressure Management in Patients Undergoing Off-pump Coronary Artery Bypass GraftingNot yet recruitingNCT07787364Not applicable
- Intravenous Infusion of Low Dose Ketamine Versus Dexmedetomedine for Delirium Treatment in Acute Heart FailureNot yet recruitingNCT07781462Phase 4
- Intrathecal Morphine Versus Intrathecal Dexmedetomidine Compared to Placebo for Postoperative Pain Relief After Spine Fixation SurgeriesRecruitingNCT07777627Not applicable
- Effect of Nebulized Dexmedetomidine on Central Sensitization and Chronification in MigraineRecruitingNCT07769255Not applicable
- Intranasal Dexmedetomidine vs. Oral Chloral Hydrate for Pediatric Orthopedic Procedural SedationNot yet recruitingNCT07768566Not applicable
- Effect of Dexmedetomidine Combined With FNB/ACB on Sleep Quality After Knee SurgeryRecruitingNCT07767383Phase 4
- A Study of LY4355756 in Healthy ParticipantsRecruitingNCT07765498Phase 1
- Effects Of Propofol And Sevoflurane On Plasma Mirna Levels İn Living Kidney DonorsRecruitingNCT07760402Not applicable
- Fast-Track Anesthesia in Minimally Invasive Cardiac Surgery: Dexmedetomidine and Erector Spinae Plane Block vs Opioid-Based AnesthesiaNot yet recruitingNCT07749274Not applicable
- Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric GastroscopyNot yet recruitingNCT07748884Phase 4
- Intravenous Dexmedetomidine as a Perioperative Autonomic-Immune NeuromodulatorNot yet recruitingNCT07743853Not applicable
- A Study on the Preventive Effect of Electroacupuncture Combined With Dexmedetomidine in Post-stroke DepressionNot yet recruitingNCT07739329Phase 4
- Exploration of Appropriate BIS Range and Propofol Effect-site Concentration During Total Intravenous Anesthesia With Concomitant Adjuvants.Not yet recruitingNCT07736352Not applicable
- Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI StudyEnrolling by invitationNCT07705022Phase 2
- The Effects of Midazolam, Dexmedetomidine, and Esketamine on Bispectral Index and Raw Electroencephalogram in Patients Under Propofol-Remifentanil Baseline AnesthesiaNot yet recruitingNCT07699523Not applicable
- REmifentanil And Dexmedetomidine for EarlY Intensive Blood Pressure Lowering in ICH.Not yet recruitingNCT07695220Not applicable
- Comparing Sedatives for Intracranial Pressure Control in Traumatic Brain InjuryNot yet recruitingNCT07678216Not applicable
- Preoperative Nebulized Dexmedetomidine Versus Nebulized Magnesium Sulphate in Reducing Emergence Agitation in FESSEnrolling by invitationNCT07677917Phase 1
- ACB and iPACK Blocks With Intravenous Dexamethasone and Perineural Dexmedetomidine in Total Knee ArthroplastyNot yet recruitingNCT07677215Not applicable
- Hemodynamic Effect of Dexmedetomidine Versus Magnesium Sulphate as an Adjuvant to Lidocaine in Preemptive Peribulbar Block in Patients Undergoing Dacryocystorhinostomy Under General AnesthesiaRecruitingNCT07675616Not applicable
- a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right ShuntsRecruitingNCT07669012Phase 1
- Effects of Dexmedetomidine on Sublingual Microcirculation and Vascular Waterfall Phenomenon in Patients With Septic ShockNot yet recruitingNCT07657715Not applicable
- Opioid-Free Versus Opioid-Based Sedation for Endoscopic ProceduresNot yet recruitingNCT07649746Not applicable
- The Effects of Different Anesthetics on the Brain's Neural NetworksNot yet recruitingNCT07644663Phase 4
- The Analgesic Efficacy of Dexmedetomidine Versus Fentanyl as an Adjuvant to Bupivacaine in Ultrasound Guided Peripheral Nerve Blocks as a Solo Anesthetic Technique in High Risk Patients Undergoing Unilateral Above Knee Amputation .RecruitingNCT07640516Not applicable
- Timing Of Midazolam İn Children Undergoing Adenotonsillectomy: Effects On Stress, Cortisol, And RecoveryNot yet recruitingNCT07622641Not applicable
- Dexmedetomidine vs Lignocaine for Reducing Intubation-Induced Hemodynamic Responses in Cardiac Surgery: A Randomized Controlled TrialRecruitingNCT07611890Phase 4
- Sevoflurane vs Propofol Anesthesia in Obese Patients Undergoing Lumbar SurgeryRecruitingNCT07611240Not applicable
- Intranasal Dexmedetomidine-esketamine on Sleep and Cognition in Older Adults With Mild-to-moderate Cognitive ImpairmentNot yet recruitingNCT07610343Phase 4
- Dexmedetomidine vs Propofol-lidocaine Mixture in Preventing the Post Operative Emergence Agitation Following Sevoflurane AnasthesiaNot yet recruitingNCT07601698Phase 4
- Dexmedetomidine Nasal Spray on Postoperative Delirium in Elderly Thoracoscopic Lung Resection PatientsNot yet recruitingNCT07579806Phase 4
- Long-term Follow-up of Dexmedetomidine-esketamine and tDCS for Neurocognitive Complications After SurgeryNot yet recruitingNCT07576543Phase 4
- Dexmedetomidine-esketamine and tDCS for Prevention of Neurocognitive Complications After SurgeryNot yet recruitingNCT07576517Phase 4
- Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in ChildrenNot yet recruitingNCT07570160Phase 4
- Efficacy of the Alpha 2 Agonist Dexmedetomidine for Sympathetic Deactivation in REfractory Septic ShockNot yet recruitingNCT07569536Phase 3
- Adding Dexmedetomidine or Clonidine to Spinal Anesthesia for Cesarean DeliveryNot yet recruitingNCT07567495Phase 4
- Intranasal Dexmedetomidine vs Oral Midazolam for Premedication in Pediatric SurgeryRecruitingNCT07565116Not applicable
- Synaptic Mechanisms of Continuous Theta Burst Stimulation in DepressionRecruitingNCT07560878Early Phase 1
- Effect of Opioid-Free vs Opioid-Based Anesthesia on Postoperative Pain and Emergence Agitation in Children Undergoing Cleft SurgeryRecruitingNCT07557576Not applicable
- Patient Quality of Recovery After TAVR With Different Sedation RegimensRecruitingNCT07556523Phase 4
- Dexmedetomidine and Propofol for Sedation in Cataract Surgery.RecruitingNCT07556133Not applicable
- Intranasal Dexmedetomidine for Acute Anxiety State in AdultsRecruitingNCT07550881Phase 2
- Intranasal Dexmedetomidine and Perioperative Myocardial InjuryNot yet recruitingNCT07549282Phase 4
- Phenobarbital for Agitated DeliriumNot yet recruitingNCT07548489Phase 3
- Impact on Delirium of the Use of DEXmedetomidine as First-line Sedation in PEDIAtric Intensive CareNot yet recruitingNCT07542990Phase 3
- A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for InsomniaRecruitingNCT07542756Phase 4
- Diphenhydramine as an Adjunct to Moderate Sedation for Procedural First Trimester AbortionsRecruitingNCT07542730Phase 4
- MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES)Not yet recruitingNCT07538284Phase 2/3
- The Effect of Paedfusor TCI, Eleveld TCI, and Sevoflurane Anesthesia on Postoperative Awakening Agitation in Pediatric PatientsRecruitingNCT07534956Not applicable
- Respiratory and Haemodynamic Effects of Conscious Sedation With Dexmedetomidine for a TAVI ProcedureRecruitingNCT07532733Not applicable
- A Study to Investigate the Safety and PK of VH4770359 in Healthy ParticipantsRecruitingNCT07525544Phase 1
- Intrathecal Dexmedetomidine With Bupivacaine, in Patients Undergoing Knee Orthopedic SurgeryRecruitingNCT07522736Not applicable
- The Effect of Dormicum-Ketamine Versus Dexmedetomidine on Emergence Delirium During Deep Sedation in Paediatric Burn PatientsRecruitingNCT07519863Phase 2
- Comparative Study Between Different Additives to Lidocaine 2٪ for Peribulbar Block in Vitreoretinal SurgeryNot yet recruitingNCT07519694Not applicable
- a Prospective Randomised Study Evaluating the Efficacy of Intranasal Midazolam and Dexmedetomidine as a Sedative Agent in Management of Mandible FractureEnrolling by invitationNCT07502651Early Phase 1
- Intranasal Dexmedetomidine for Postpartum Depression PreventionNot yet recruitingNCT07501728Not applicable
- Intranasal Dexmedetomidine for Prevention of Intrapartum FeverNot yet recruitingNCT07501221Not applicable
- Dexmedetomidine for Invasive Ventilation In the NEOnateNot yet recruitingNCT07493785Phase 2/3
- Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve SurgeryNot yet recruitingNCT07482540Not applicable
- Early Dexmedetomidine and Sympathetic Regulation in SepsisNot yet recruitingNCT07470775Phase 4
- Dexmedetomidine for Improving Emergence Quality in Thyroid SurgeryRecruitingNCT07462195Phase 4
- Comparison of Two Sedative Agents in Terms of Controlled HypotensionNot yet recruitingNCT07460050Not applicable
- Prospective IR-led Sedation FeasibilityRecruitingNCT07443254Phase 1/2
- Comparison Between Total Intravenous Anesthesia With Magnesium Sulphate Versus Total Intravenous Anesthesia With Dexmedetomidine in Patients Undergoing Lumbar Spine SurgeriesNot yet recruitingNCT07443163Phase 3
- Perioperative Multimodal Analgesia for Supratentorial CraniotomyRecruitingNCT07441421Not applicable
- Use of Dexmedetomidine to Improve Pain Control and Recovery After Laparocopic-Assisted Bowel Surgery in AdultsNot yet recruitingNCT07434310Phase 3
- Lorazepam for Delirium Prevention in Critically Ill Patients With High Anttila-IndexNot yet recruitingNCT07428681Phase 4
- Dexmedetomidine-Midazolam vs. Ketamine-Midazolam on Emergence DeliriumRecruitingNCT07427446Phase 4
- Attenuate the Stress Response in Laparoscopic CholecystectomyNot yet recruitingNCT07425444Phase 4
- DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial)Not yet recruitingNCT07398066Not applicable
- Understanding the Role of the Locus Coeruleus in InsomniaRecruitingNCT07392177Phase 2
- Opioid-Free Anesthesia Versus Opioid Based Anesthesia For Adolescent Idiopathic ScoliosisRecruitingNCT07389096Phase 4