Hypnotics and Sedatives: all 2,749 studies that test it

Page 5 of 28. Open to participants first (425), then studies with results posted, then the rest; newest registration first within each.

• Th Effects of a Drug Dexmedotemidine in Regional Anesthesia in Participants Undergoing Upper Limb SurgeriesRecruitingNCT04981951Not applicable
• Anesthesia Induced Brain Cancer Survival (ABC Survival): A Feasibility StudyRecruitingNCT04962672Not applicable
• Low Dose Dexmedetomidine Versus Normal Saline in Multiple Fracture RibsRecruitingNCT04928300Phase 3
• Cardioprotective Effect of Dexmedetomidine in Patients With ST-segment Elevation Myocardial InfarctionRecruitingNCT04912518Not applicable
• Dexmedetomidine and Midazolam Nebulization as Sedation During Cesarean Delivery in Pre-eclampsiaRecruitingNCT04873596Phase 2
• Effects of Dexmedetomidine in Patients With Agitated Delirium in Palliative CareRecruitingNCT04824144Phase 1/2
• Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Rescue After Failed Pediatric Procedural SedationRecruitingNCT04822064Not applicable
• Pediatric DeliriumEnrolling by invitationNCT04669457Phase 4
• Effects of Dexmedetomidine on Intraocular Pressure During Scheduled Spine SurgeriesRecruitingNCT04628663Not applicable
• Total Intravenous Anesthesia and Recurrence Free SurvivalRecruitingNCT04513808Phase 3
• Propofol vs Sevo for Paediatric Tumor SurgeryRecruitingNCT04475705Phase 4
• The Effect of Intraoperative Dexmedetomidine on Postoperative Morphine Requirements After Breast Cancer SurgeryRecruitingNCT04454515Not applicable
• a Phase III Trial of Safety and Efficacy of Premedication With Dexmedetomidine and Midazolam in Pediatric PatientsRecruitingNCT04356638Phase 3
• Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery PatientsRecruitingNCT04289142Phase 4
• Stem Cell Transplantation in Crohn's DiseaseRecruitingNCT04224558Phase 1/2
• Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal SurgeryRecruitingNCT04144933Phase 3
• Sedation Versus Protective Stabilization for Pediatric Dental TreatmentRecruitingNCT04119180Phase 4
• Sedation Efficacy of Dexmedetomidine Versus Midazolam in Critically Ill Ventilated ChildrenRecruitingNCT04082767Phase 3
• Nonopioid Analgesia After Labral SurgeryRecruitingNCT03825809Phase 2/3
• Effects of an Opioid Free/Sparing Care Pathway for Patients Undergoing Obesity SurgeryRecruitingNCT03756961Not applicable
• Intranasal Dexmedetomidine Sedation and Analgesia During Pediatric Emergency Room ProceduresRecruitingNCT03564093Phase 4
• Long Term Evaluation and Management of Atrial Fibrillation in Pacemaker PatientsNot yet recruitingNCT03401593Not applicable
• Effect of Dexmedetomidine on the Minimum Alveolar Concentration of SevofluraneRecruitingNCT03384563Phase 4
• Dexmedetomidine Wound Infiltration in Cesarean SectionRecruitingNCT03382938Not applicable
• The Effects of Different Anesthetics on Functional ConnectivityRecruitingNCT03343873Not applicable
• Evaluation of Vamorolone CYP3A4 Induction on Midazolam (a Sensitive CYP 3A4 Substrate) PharmacokineticsCompletedNCT06689527Phase 1Results posted
• A Study in Healthy Men to Test Whether Zongertinib Affects How 3 Other Medicines (Midazolam, Omeprazole, and Repaglinide) Are Taken up and Processed by the BodyCompletedNCT06494761Phase 1Results posted
• Emergence Agitation Between Dexmedetomidine and Sevoflurane AnesthesiaCompletedNCT06482125Not applicableResults posted
• A Drug Drug Interaction (DDI) Study of Pirtobrutinib (LOXO-305) and Different Formulations of Midazolam in Healthy ParticipantsCompletedNCT06180967Phase 1Results posted
• Antiseizure Medication in Seizure Networks at Early Acute Brain InjuryTerminatedNCT06081283Phase 4Results posted
• Tachyphylaxis, Tolerance, & Withdrawal Post Treatment With Igalmi for Agitation in Schizophrenia or Bipolar DisorderCompletedNCT06041646Phase 4Results posted
• Awake Caudal Catheter vs General AnesthesiaCompletedNCT05919732Phase 4Results posted
• A Study to Compare How Different Substances (Caffeine, Warfarin, Omeprazole, Metoprolol, and Midazolam) Are Handled by the Body of Healthy People and People With Liver CirrhosisCompletedNCT05741385Not applicableResults posted
• Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY III)TerminatedNCT05665088Phase 3Results posted
• Music vs Midazolam During Preop Nerve Block Placement - Part 2 Study On Anxiolytic Options Before Peripheral Nerve BlocksTerminatedNCT05610969Phase 1/2Results posted
• A Study to Learn Safety and Blood Levels of PF-07817883 in Healthy PeopleCompletedNCT05580003Phase 1Results posted
• Perpetrator DDI Potential of Givinostat as Inhibitor and Inducer of CYP3A and P-gp ActivityCompletedNCT05492318Phase 1Results posted
• Effectiveness of Clonidine, Dexmedetomidine, and Fentanyl Adjuncts for Labor Epidural AnalgesiaCompletedNCT05487196Phase 2Results posted
• A Study to Assess the Effect of Cefiderocol on the Pharmacokinetics (PK) of Midazolam in Healthy ParticipantsCompletedNCT05395104Phase 1Results posted
• A Study of Effects of Selpercatinib (LY3527723) on Midazolam in Healthy ParticipantsCompletedNCT05338476Phase 1Results posted
• Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled TrialCompletedNCT05321121Phase 4Results posted
• Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERiesCompletedNCT05279898Not applicableResults posted
• Randomized Trial of Sedative Choice for IntubationCompletedNCT05277896Phase 4Results posted
• An Efficacy, and Safety Study Of BXCL501 For The Treatment Of Agitation Associated With DementiaTerminatedNCT05276830Phase 2Results posted
• Dexmedetomidine in the Treatment of Agitation Associated With Dementia (TRANQUILITY II)CompletedNCT05271552Phase 3Results posted
• Ketamine and Kidney Injury in Cardiac SurgeryActive, not recruitingNCT05268562Phase 4Results posted
• A Study in Healthy Men to Test Whether BI 425809 Influences the Amount of Midazolam in the BloodCompletedNCT05258110Phase 1Results posted
• Central Nervous System Effects Following Infusion of Diphenhydramine Using Pharmacokinetic and Pharmacodynamic ModelingTerminatedNCT05219604Phase 4Results posted
• Pharmacokinetics Study of VALTOCO® in Pediatric Subjects With EpilepsyCompletedNCT05076838Phase 1/2Results posted
• Drug-Drug Interaction Study to Estimate the Effect of PF-07321332/Ritonavir and Ritonavir on Midazolam in Healthy ParticipantsCompletedNCT05032950Phase 1Results posted
• Multimodal Versus Opioid aNalgesia in carDiAc SurgeryCompletedNCT04987372Phase 4Results posted
• Validation of the Drug Impaired Driving Scenario (DIDS) on the CRCDS-miniSimCompletedNCT04970342Phase 1Results posted
• Remote Treatment of Alcohol WithdrawalCompletedNCT04858490Not applicableResults posted
• Effect of Dexmedetomidine of Gastrointestinal MotilityCompletedNCT04798482Phase 4Results posted
• A Study to Test How Healthy Men Tolerate Different Doses of BI 1595043CompletedNCT04789304Phase 1Results posted
• Dexmedetomidine Use in Infants Undergoing Cooling Due to Neonatal Encephalopathy (DICE Trial)CompletedNCT04772222Phase 2Results posted
• PROUD Study - Preventing Opioid Use DisordersTerminatedNCT04766996Phase 4Results posted
• The Effect of Opioid-Free Anesthesia in TMJ SurgeryCompletedNCT04724759Phase 2Results posted
• Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) ICompletedNCT04680910Phase 1Results posted
• Neuroimaging Study of Dexmedetomidine-Induced AnalgesiaCompletedNCT04656470Phase 2/3Results posted
• Combination Drug-Therapy for Patients With Untreated Obstructive Sleep ApneaCompletedNCT04639193Phase 2Results posted
• Ketamine Versus Midazolam for Recurrence of Suicidality in AdolescentsCompletedNCT04592809Phase 3Results posted
• Dose-Finding Study of Intranasal Midazolam for Procedural Sedation in ChildrenCompletedNCT04586504Phase 1/2Results posted
• A Study of LY3522348 in Healthy ParticipantsCompletedNCT04559568Phase 1Results posted
• Evaluation of Effect of Vonoprazan on Midazolam Pharmacokinetics in Healthy ParticipantsCompletedNCT04545944Phase 1Results posted
• Opioid-Free Anesthetic for TonsillectomyTerminatedNCT04528173Phase 4Results posted
• Dexmedetomidine in the Treatment of Symptoms Of Acute Opioid WithdrawalCompletedNCT04470050Phase 1/2Results posted
• Recovery After Total Intravenous Anesthesia With Ketofol Versus Mixture of Ketofol and Lidocaine for Short Pediatric SurgeryCompletedNCT04467424Phase 2Results posted
• Evaluation of Pharmacokinetic Interaction Between GSK3640254 and Caffeine, Metoprolol, Montelukast, Flurbiprofen, Omeprazole, Midazolam, Digoxin, and Pravastatin in Healthy AdultsCompletedNCT04425902Phase 1Results posted
• Implications of Anesthetics on Sleep ConsolidationTerminatedNCT04329091Phase 4Results posted
• Efficacy and Safety of Intravenous Phenobarbital in Neonatal SeizuresTerminatedNCT04320940Phase 3Results posted
• Prescription Medication InteractionsCompletedNCT04315181Phase 1Results posted
• Clinical Study to Investigate the Effect of the Combination of Psychotropic Drugs and an Opioid on VentilationCompletedNCT04310579Phase 1Results posted
• Dexmedetomidine in the Treatment of Agitation Associated With Bipolar DisorderCompletedNCT04276883Phase 3Results posted
• Dexmedetomidine in the Treatment of Agitation Associated With SchizophreniaCompletedNCT04268303Phase 3Results posted
• Sub-Lingual Dexmedetomidine in Agitation Associated With DementiaCompletedNCT04251910Phase 1/2Results posted
• Effect of Obesity on Proton Pump InhibitorsCompletedNCT04248335Phase 4Results posted
• Safety and Efficacy of Dexmedetomidine (DEX) for Sedation of Subjects ≥1 Month to <17 Years Undergoing MRI ScansCompletedNCT04237792Phase 4Results posted
• Impact of Propofol Reduction in Anesthesia InductionCompletedNCT04194151Phase 4Results posted
• Phase 2 Study IV QUZYTTIR™ (Cetirizine Hydrochloride Injection) vs V DiphenhydramineCompletedNCT04189588Phase 2Results posted
• Comparison of Bolus Dosing of Methohexital and Propofol in Elective Direct Current CardioversionCompletedNCT04187196Phase 4Results posted
• Comparing Risk and Severity of IRRs in Patients Premedicated With Cetirizine vs. Diphenhydramine Prior to OcrelizumabCompletedNCT04175834Phase 3Results posted
• Evaluation of Safety, Tolerability, Pharmacokinetics, Drug-Drug and Food Interactions of Single and Multiple Doses of S-648414 in Healthy AdultsCompletedNCT04147715Phase 1Results posted
• A Study in Healthy Men and Women to Test How Well Different Doses of BI 1323495 Are ToleratedCompletedNCT04107805Phase 1Results posted
• Comparing Pediatric Dental Oral Sedation Outcomes With and Without Meperidine in Children Aged 3-7 YearsCompletedNCT04068948Phase 4Results posted
• Memory & Conditioning Under AnesthesiaCompletedNCT04062123Phase 1Results posted
• Controlling Rapid Atrial Fibrillation With DexmedetomidineTerminatedNCT04042727Phase 2/3Results posted
• Multi-modal Assessment of Gamma-aminobutyric Acid (GABA) Function in PsychosisCompletedNCT04004416Phase 4Results posted
• Total Joint Arthroplasty and SleepCompletedNCT03968939Phase 4Results posted
• Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSDCompletedNCT03937713Phase 4Results posted
• Comparison of Etomidate Plus Propofol, Etomidate Alone on Induction of AnesthesiaCompletedNCT03820388Phase 4Results posted
• Nonopioid Analgesia After Anterior Cruciate Ligament ReconstructionCompletedNCT03818932Phase 2/3Results posted
• Nonopioid Analgesia After Rotator Cuff RepairCompletedNCT03818919Phase 2Results posted
• The Effects of Sedatives on Tobacco Use DisorderCompletedNCT03813121Phase 1/2Results posted
• Effect of Dexmedetomidine on Postoperative Glucose and Insulin Levels.CompletedNCT03809182Phase 4Results posted
• The Use of Dexmedetomidine for EEG Sedation in Children With Behavioural DisordersCompletedNCT03799783Phase 2Results posted
• Effect of Intraoperative Dexmedetomidine on Early Postoperative Cognitive DysfunctionCompletedNCT03793751Phase 4Results posted
• Benzodiazepines for the Reduction of Distress and Pain During and After Emergency Department CareTerminatedNCT03756038Phase 2Results posted
• A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric PatientsCompletedNCT03714919Phase 2Results posted
• Clonidine Versus Phenobarbital as Adjunctive Therapy for Neonatal Abstinence SyndromeCompletedNCT03670160Phase 2Results posted

← Hypnotics and Sedatives overview