Drug
Droxidopa clinical trials
Also written Northera, L-DOPS and L-threo-DOPS.
- studies test it
- 38
- open now
- 3
- in phase 3
- 9
- first study started
- 1999
Keep track of what changes. Save the Droxidopa studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
38 studies that test it; most in 2016 (5)
| Year | Studies |
|---|---|
| 1999 | 1 |
| 2004 | 1 |
| 2007 | 2 |
| 2008 | 3 |
| 2009 | 3 |
| 2010 | 3 |
| 2011 | 4 |
| 2012 | 3 |
| 2013 | 1 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 5 |
| 2017 | 2 |
| 2018 | 3 |
| 2019 | 1 |
| 2021 | 2 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 10
- Phase 2
- 18
- Phase 3
- 9
- Phase 4
- 6
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 16 · Other 22
Chelsea Therapeutics (14) · Vanderbilt University Medical Center (2) · St. Joseph's Hospital and Medical Center, Phoenix (2) · Stephen G. Kaler, MD (1) · University Hospital, Toulouse (1) · James J. Peters Veterans Affairs Medical Center (1) · H. Lundbeck A/S (1) · Alberto Espay, MD, MSc (1)
Often tested with
Tested in the same studies.
Carbidopa (4) · Midodrine (1) · Atenolol (1) · Entacapone (1)
Studies
Open first, then newest update. How each study uses Droxidopa is read from its arms, and is right about nine times in ten.
Testing it · 38
- NORTHERA (DROXIDOPA) for Dysautonomia in Pediatric Survivors of Menkes DiseaseRecruitingPhase 1/2Stephen G. KalerNCT07398508Written as Droxidopa Oral Product
- Droxidopa to Increase Mean Arterial Pressure in Decompensated Cirrhosis Patients With Acute Kidney InjuryRecruitingPhase 2Giuseppe Cullaro, MDNCT06937307Written as Droxidopa capsules
- Droxidopa / Pyridostigmine in Orthostatic HypotensionEnrolling by invitationPhase 2Mayo ClinicNCT01370512Written as Droxidopa
- Effects of Midodrine and Droxidopa on Splanchnic Capacitance in Autonomic FailureTerminatedPhase 1Vanderbilt University Medical CenterNCT02897063Written as Droxidopa
- NORTHERA (DROXIDOPA) for Dysautonomia in Adult Survivors of Menkes Disease and Occipital Horn SyndromeCompletedPhase 1/2Stephen G. Kaler, MDNCT04977388Written as Droxidopa
- Efficacy of L-threo DOPS on Orthostatic Hypotension Symptoms and Other Non-motor Symptoms in Patients With MSACompletedPhase 2/3University Hospital, ToulouseNCT02071459Written as L-Threo DOPS
- Dose Response to the Norepinephrine Precursor Droxidopa in Hypotensive Individuals With Spinal Cord InjuryCompletedPhase 4James J. Peters Veterans Affairs Medical CenterNCT03602014Written as Northera
- Study of Droxidopa Treatment in Adults With Attention Deficit Hyperactivity Disorder With Co-administration of CarbidopaCompletedPhase 2Chelsea TherapeuticsNCT00983814Written as Droxidopa+Carbidopa
- Study To Assess The Clinical Benefit Of Droxidopa And Droxidopa/Carbidopa In Subjects With FibromyalgiaCompletedPhase 2Chelsea TherapeuticsNCT01323374Written as Droxidopa
- Clinical Study of Droxidopa in Patients With Neurogenic Orthostatic Hypotension (NOH) (Droxi-304)CompletedPhase 3Chelsea TherapeuticsNCT01132326Written as Droxidopa
- Sustained Effect of Droxidopa in Symptomatic Neurogenic Orthostatic HypotensionCompletedPhase 4H. Lundbeck A/SNCT02586623Written as Droxidopa capsules
- Lundbeck TOMs Orthostatic HypotensionCompletedPhase 4Alberto Espay, MD, MScNCT04510922Written as Droxidopa 100 MG [Northera]
- Brain Perfusion & Oxygenation in Parkinson's Disease With NOHCompletedPhase 4William Ondo, MDNCT03229174Written as Droxidopa
- Treatment of Orthostatic HypotensionTerminatedPhase 2/3Vanderbilt UniversityNCT00581477Written as Droxidopa Oral Product
- Safety and Efficacy of Droxidopa for Fatigue in Patients With ParkinsonismWithdrawnPhase 2Loma Linda UniversityNCT03446807Written as Droxidopa
- A Randomized, Double-Blind, Placebo-Controlled Study of Droxidopa for Fatigue in Parkinson's DiseaseTerminatedPhase 4The Cooper Health SystemNCT03034564Written as Northera
- Norepinephrine-targeted Therapy for Action Control in Parkinson DiseaseCompletedPhase 4Vanderbilt University Medical CenterNCT03115827Written as Droxidopa
- Effect of L-Dihydroxyphenylserine (L-DOPS) on Falls in Patients With Neurogenic Orthostatic Hypotension (NOH)Status unknownPhase 2St. Joseph's Hospital and Medical Center, PhoenixNCT03567447Written as Droxidopa
- Effect of L-Dihydoxyphenylserine on Locomotion, Postural Stability, and Fall Risk Reduction in Parkinson DiseaseStatus unknownPhase 2St. Joseph's Hospital and Medical Center, PhoenixNCT02812147Written as L-DOPS
- Effects of Droxidopa When Measuring Gait Speed, Kyphosis, and Functional Reach in Parkinson's DiseaseCompletedNot applicableColorado Springs Neurological AssociatesNCT03173781Written as droxidopa
Codes
What other systems call Droxidopa · ClinicalTrials.gg INT008438
- MeSH (NLM) D015103DroxidopaConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) J7A92W69L7DROXIDOPAConfirmed FDA, NLM, Wikidata
- RxNorm 1489913Confirmed FDA, Wikidata
- Wikidata Q907853droxidopaConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C73266DroxidopaConfirmed FDA, Wikidata
- DrugBank DB06262One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D015103 | Droxidopa | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | J7A92W69L7 | DROXIDOPA | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1489913 | — | Confirmed FDA, Wikidata |
| Wikidata | Q907853 | droxidopa | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C73266 | Droxidopa | Confirmed FDA, Wikidata |
| DrugBank | DB06262 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.