Drug
Dacarbazine clinical trials
Also written DTIC, DTIC-Dome and WR-139007.
- studies test it
- 83
- open now
- 10
- in phase 3
- 17
- first study started
- 1995
Keep track of what changes. Save the Dacarbazine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Brand
Development codes
Studies by the year they started
82 studies that test it; most in 2005 (6)
| Year | Studies |
|---|---|
| 1995 | 1 |
| 1996 | 1 |
| 1997 | 1 |
| 1998 | 3 |
| 1999 | 2 |
| 2000 | 1 |
| 2001 | 1 |
| 2002 | 1 |
| 2003 | 3 |
| 2004 | 2 |
| 2005 | 6 |
| 2006 | 3 |
| 2007 | 6 |
| 2008 | 4 |
| 2009 | 4 |
| 2010 | 5 |
| 2011 | 4 |
| 2012 | 6 |
| 2013 | 2 |
| 2014 | 1 |
| 2015 | 1 |
| 2016 | 1 |
| 2017 | 5 |
| 2018 | 2 |
| 2019 | 5 |
| 2020 | 1 |
| 2021 | 1 |
| 2022 | 1 |
| 2023 | 1 |
| 2024 | 2 |
| 2025 | 4 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 16
- Phase 2
- 56
- Phase 3
- 17
- Phase 4
- 2
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
- Melanoma
- 40
Who runs them
Industry 20 · Other 63
M.D. Anderson Cancer Center (5) · University of Cologne (4) · Bristol-Myers Squibb (3) · Takeda (2) · Fondazione Italiana Linfomi - ETS (2) · University of Washington (2) · Eastern Cooperative Oncology Group (2) · National Cancer Institute (NCI) (2)
Often tested with
Tested in the same studies.
Vinblastine (26) · Doxorubicin (23) · Brentuximab Vedotin (13) · Bleomycin (12) · Cisplatin (9) · Cyclophosphamide (7) · Vincristine (7) · Etoposide (6)
Studies
Open first, then newest update. How each study uses Dacarbazine is read from its arms, and is right about nine times in ten.
Testing it · 83
- Cryoablation Combined With Hepatic Arterial Infusion of Iparomlimab and Tuvonralimab (QL1706), Intravenous Dacarbazine, and Oral Lenvatinib in Patients With Liver Metastases From Malignant Melanoma: a Single-arm, Phase II, Prospective TrialRecruitingPhase 2Sun Yat-sen UniversityNCT07847359Written as Dacarbazine
- Personalized Reduction of Chemotherapy Intensity Through ctDNA Evaluation for the Treatment of Patients With Advanced Hodgkin LymphomaRecruitingPhase 2University of WashingtonNCT06745076Written as Dacarbazine
- A Study of BV-AVD in People With Bulky Hodgkin LymphomaRecruitingPhase 2Memorial Sloan Kettering Cancer CenterNCT06377566Written as Dacarbazine
- Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS)RecruitingPhase 3Advenchen Laboratories, LLCNCT03016819Written as Dacarbazine
- A Study of Brentuximab Vedotin With Doxorubicin, Vinblastine and Dacarbazine in Adults With Hodgkin Lymphoma in IndiaRecruitingPhase 4TakedaNCT06831370Written as Dacarbazine
- Feasibility of Total Neoadjuvant Treatment With HYPErthermia in Patients With High-risk Extremity and Trunk Soft Tissue Sarcoma (TNT-HYPE)RecruitingPhase 2Swiss Cancer InstituteNCT06835049Written as Dacarbazine
- Nivo40-AVD for Advanced Classic Hodgkin LymphomaRecruitingPhase 2National Medical Research Radiological Centre of the Ministry of Health of RussiaNCT06984146Written as Dacarbazine
- BrECADD Therapy in Stage 2 B-IV Hodgkin LymphomaRecruitingPhase 2University of MiamiNCT07002216Written as Dacarbazine
- High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)RecruitingPhase 3Gustave Roussy, Cancer Campus, Grand ParisNCT04221035Written as Dacarbazine
- BV-AVD-R Treatment Children Hodgkin's LymphomaEnrolling by invitationPhase 2Beijing Children's HospitalNCT06201507Written as Dacarbazine
- PET Adapted Brentuximab Vedotin and Pembrolizumab in Combination With Doxorubicin and Dacarbazine in Classic Hodgkin LymphomaActive, not recruitingPhase 2M.D. Anderson Cancer CenterNCT05922904Written as Dacarbazine
- Doxorubicin, Vinblastine, Dacarbazine, Brentuximab Vedotin, and Nivolumab in Treating Patients With Stage I-II Hodgkin LymphomaActive, not recruitingPhase 2Academic and Community Cancer Research UnitedNCT03233347Written as Dacarbazine
- Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II StudyActive, not recruitingPhase 2European Organisation for Research and Treatment of Cancer - EORTCNCT03517137Written as Dacarbazine
- Adjuvant Therapy of Skin Melanoma With Alpha Interferon and NaderinCompletedPhase 2MIPO ClinicNCT07671495Written as Dacarbazine (DTIC)
- CytoreductiveSurgery & HIPEC w/Gemcitabine+Chemotherapy w/Dacarbazine in Uterine LeiomyosarcomaCompletedPhase 2Stanford UniversityNCT04727242Written as Dacarbazine
- Pediatric Classical Hodgkin Lymphoma Consortium Study: cHOD17Active, not recruitingPhase 2St. Jude Children's Research HospitalNCT03755804Written as DTIC
- Brentuximab Vedotin and Combination Chemotherapy in Treating Older Patients With Previously Untreated Stage II-IV Hodgkin LymphomaCompletedPhase 2Northwestern UniversityNCT01476410Written as dacarbazine
- Preconditioning of Tumor, Tumor Microenvironment and the Immune System to ImmunotherapyCompletedPhase 2University of Erlangen-Nürnberg Medical SchoolNCT04225390Written as Dacarbazine (DTIC)
- Camrelizumab Combined With AVD in the First-line Treatment for Patients With Advanced Classical Hodgkin's LymphomaActive, not recruitingPhase 2Henan Cancer HospitalNCT04067037Written as Dacarbazine
- A Study of Brentuximab Vedotin + Adriamycin, Vinblastine, and Dacarbazine in Pediatric Participants With Advanced Stage Newly Diagnosed Hodgkin LymphomaActive, not recruitingPhase 1/2TakedaNCT02979522Written as Dacarbazine
See all 83 studies that test Dacarbazine →
Given in every arm · 52 — Dacarbazine is usual care beside what is tested
- A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and NivolumabRecruitingPhase 3National Cancer Institute (NCI)NCT05675410Written as Dacarbazine
- Phase II Study Of Nivolumab Plus AVD In Pediatric, Adolescent, And Young Adult Patients With CHLRecruitingPhase 2M.D. Anderson Cancer CenterNCT07551583Written as Dacarbazine
- Pembrolizumab in Combination With Chemotherapy for the Treatment of Frail Hodgkin Lymphoma Patients Ineligible for Standard TreatmentRecruitingPhase 2City of Hope Medical CenterNCT07275216Written as Dacarbazine
- Brentuximab Vedotin in Early Stage Hodgkin LymphomaRecruitingPhase 3University College, LondonNCT04685616Written as Dacarbazine
- Brentuximab Vedotin for Newly Diagnosed cHL in Chinese CAYA Based on PET/CT AssessmentRecruitingPhase 2/3Children's Cancer Group, ChinaNCT06563245Written as Dacarbazine
- First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)RecruitingPhase 3State Budgetary Healthcare Institution, National Medical Surgical Center N.A. N.I. Pirogov, Ministry of Health of RussiaNCT04638790Written as Dacarbazine
- Treatment for Classical Hodgkin Lymphoma in Children and AdolescentsRecruitingNot applicableGALIA AVRAHAMINCT02797717Written as Dacarbazine
- Brentuximab Vedotin Plus AD in Non-bulky Limited Stage Hodgkin LymphomaCompletedPhase 2Massachusetts General HospitalNCT02505269Written as Dacarbazine
- Immunotherapy (Nivolumab or Brentuximab Vedotin) Plus Combination Chemotherapy in Treating Patients With Newly Diagnosed Stage III-IV Classic Hodgkin LymphomaActive, not recruitingPhase 3National Cancer Institute (NCI)NCT03907488Written as Dacarbazine
- Safety and Efficacy of Pembrolizumab (MK-3475) in Children and Young Adults With Classical Hodgkin Lymphoma (MK-3475-667/KEYNOTE-667)Active, not recruitingPhase 2Merck Sharp & Dohme LLCNCT03407144Written as dacarbazine
- Pembrolizumab Followed by Chemotherapy for the Treatment of Patients With Classical Hodgkin LymphomaActive, not recruitingPhase 2Northwestern UniversityNCT06164275Written as Dacarbazine
- Brentuximab Vedotin Combined With AVD Chemotherapy in Patients With Newly Diagnosed Early Stage, Unfavorable Risk Hodgkin LymphomaCompletedNot applicableMemorial Sloan Kettering Cancer CenterNCT01868451Written as Dacarbazine
- A Phase I, Open-Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD6244 (ARRY-142886)CompletedPhase 1AstraZenecaNCT00600496Written as Dacarbazine
- Fitness-adapted, Pembrolizumab-based Therapy for Untreated Classical Hodgkin Lymphoma Patients 60 Years of Age and AboveActive, not recruitingPhase 2University of VirginiaNCT05404945Written as Dacarbazine
- Adcetris (Brentuximab Vedotin), Combination Chemotherapy, and Radiation Therapy in Treating Younger Patients With Stage IIB, IIIB and IV Hodgkin LymphomaActive, not recruitingPhase 2St. Jude Children's Research HospitalNCT01920932Written as Dacarbazine(R)
- A Frontline Therapy Trial in Participants With Advanced Classical Hodgkin LymphomaCompletedPhase 3TakedaNCT01712490Written as dacarbazine
- A(B)VD Followed by Nivolumab as Frontline Therapy for Higher Risk Patients With Classical Hodgkin Lymphoma (HL)Active, not recruitingPhase 1/2Memorial Sloan Kettering Cancer CenterNCT03033914Written as dacarbazine
- Clinical Trial of Brentuximab Vedotin in Classical Hodgkin LymphomaTerminatedPhase 2Seagen Inc.NCT03646123Written as dacarbazine
- Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With Stage II-IV HIV-Associated Hodgkin LymphomaCompletedPhase 1/2National Cancer Institute (NCI)NCT01771107Written as Dacarbazine
- A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)TerminatedPhase 2/3PTC TherapeuticsNCT05269355Written as Dacarbazine
Showing 20 of 52.
As the comparator · 33 — what is tested is compared with Dacarbazine
- A Phase II Trial of LM103 in Advanced MelanomaRecruitingPhase 2Suzhou BlueHorse Therapeutics Co., Ltd.NCT07310784Written as Dacarbazine, temozolomide, paclitaxel, carboplatin/cisplatin
- SUPRAME-ACTengine® IMA203 vs. Investigator's Choice of Treatment in Previously Treated, Unresectable or Metastatic Cutaneous MelanomaRecruitingPhase 3Immatics US, Inc.NCT06743126Written as Dacarbazine
- Second International Inter-Group Study for Classical Hodgkin Lymphoma in Children and AdolescentsCompletedPhase 3University of GiessenNCT02684708Written as cyclophosphamide, vincristine, prednisone, dacarbazine
- Safety and Efficacy of IMCgp100 Versus Investigator Choice in Advanced Uveal MelanomaCompletedPhase 2Immunocore LtdNCT03070392Written as Dacarbazine
- A Study to Assess Naporafenib (ERAS-254) Administered With Trametinib in Patients With NRAS-mutant Melanoma (SEACRAFT-2)Active, not recruitingPhase 3Erasca, Inc.NCT06346067Written as Dacarbazine
- IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal MelanomaActive, not recruitingPhase 2/3IDEAYA BiosciencesNCT05987332Written as Dacarbazine
- Comparison of Two Combination Chemotherapy Regimens in Treating Patients With Stage III or Stage IV Hodgkin's LymphomaCompletedPhase 3European Organisation for Research and Treatment of Cancer - EORTCNCT00049595Written as dacarbazine
- Study of Taxoprexin Injection vs. Dacarbazine in Patients With Metastatic Malignant MelanomaTerminatedPhase 3American Regent, Inc.NCT00087776Written as Dacarbazine
- A Randomized, Controlled, Multi-center, Phase III Clinical Study to Investigate Recombinant Humanized PD-1 Monoclonal Antibody Injection (JS001) Versus Dacarbazine as the 1st-line Therapy for Unresectable or Metastatic MelanomaCompletedPhase 3Shanghai Junshi Bioscience Co., Ltd.NCT03430297Written as Dacarbazine 1000mg/m2 Q3W
- Fludeoxyglucose F 18-PET/CT Imaging in Assessing Response to Chemotherapy in Patients With Newly Diagnosed Stage II, Stage III, or Stage IV Hodgkin LymphomaCompletedPhase 3University College, LondonNCT00678327Written as dacarbazine
- S0816 Fludeoxyglucose F 18-PET/CT Imaging and Combination Chemotherapy With or Without Additional Chemotherapy and G-CSF in Treating Patients With Stage III or Stage IV Hodgkin LymphomaCompletedPhase 2SWOG Cancer Research NetworkNCT00822120Written as dacarbazine
- Study of Nivolumab (BMS-936558) Compared With Dacarbazine in Untreated, Unresectable, or Metastatic MelanomaCompletedPhase 3Bristol-Myers SquibbNCT01721772Written as Dacarbazine
- A Study to Compare BMS-936558 to the Physician's Choice of Either Dacarbazine or Carboplatin and Paclitaxel in Advanced Melanoma Patients That Have Progressed Following Anti-CTLA-4 Therapy (CheckMate 037)CompletedPhase 3Bristol-Myers SquibbNCT01721746Written as Dacarbazine
- Study Comparing the Efficacy of MEK162 Versus Dacarbazine in Unresectable or Metastatic NRAS Mutation-positive MelanomaCompletedPhase 3PfizerNCT01763164Written as Dacarbazine
- Masitinib in Non-Resectable or Metastatic Stage 3/4 Melanoma Carrying a Mutation in the Juxta Membrane Domain of c-KitTerminatedPhase 3AB ScienceNCT01280565Written as Dacarbazine
- A Clinical Study to Evaluate the Safety and Efficacy of OrienX010 in Unresectable Malignant Melanoma PatientsStatus unknownPhase 2OrienGene Biotechnology Ltd.NCT04200040Written as Dacarbazine (DTIC)
- A Trial of ABI-007 Versus Dacarbazine in Previously Untreated Patients With Metastatic Malignant MelanomaCompletedPhase 3CelgeneNCT00864253Written as Dacarbazine
- A Phase II Study of Sunitinib Versus Dacarbazine in the Treatment of Patients With Metastatic Uveal MelanomaCompletedPhase 2The Clatterbridge Cancer Centre NHS Foundation TrustNCT01551459Written as Dacarbazine
- Procarbazine Hydrochloride Capsule (Natulan®) Clinical Trial ProtocolStatus unknownNot applicableLee's Pharmaceutical LimitedNCT02800447Written as ABVD
- A Study of Trabectedin (YONDELIS) in Patients With Locally Advanced or Metastatic Liposarcoma or LeiomyosarcomaCompletedPhase 3Xian-Janssen Pharmaceutical Ltd.NCT01692678Written as Dacarbazine
Showing 20 of 33.
Codes
What other systems call Dacarbazine · ClinicalTrials.gg INT007295
- MeSH (NLM) D003606DacarbazineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) 7GR28W0FJIDACARBAZINEConfirmed FDA, NLM, Wikidata
- RxNorm 3098Confirmed FDA, Wikidata
- Wikidata Q416975dacarbazineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C411DacarbazineOne source FDA
- DrugBank DB00851One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D003606 | Dacarbazine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | 7GR28W0FJI | DACARBAZINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 3098 | — | Confirmed FDA, Wikidata |
| Wikidata | Q416975 | dacarbazine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C411 | Dacarbazine | One source FDA |
| DrugBank | DB00851 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.