Neuroendocrine Tumors clinical trials
The registry lists 542 studies for Neuroendocrine Tumors across more than 10 countries. 135 are recruiting or about to start. 330 of them are mainly about Neuroendocrine Tumors (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-13. Counting its 17 narrower conditions too, such as Melanoma: 4,781 studies, 943 open.
ClinicalTrials.gov finds 4,887 studies for Neuroendocrine Tumors. How that becomes 541 here
This page counts the studies the registry files under Neuroendocrine Tumors, and those it files under no condition that list Neuroendocrine Tumorsthemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count
- 4,887Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
- −4,021Filed under a narrower condition, counted on its own pageMelanoma 3,188 · Uveal Melanoma 156 · Pheochromocytoma 125 · Carcinoma, Medullary 117 · Neuroma, Acoustic 98 · Carcinoma, Neuroendocrine 93 · 9 more
- −106List Neuroendocrine Tumors as a condition, but the registry did not file them under itMost often written as “Pancreatic Neuroendocrine Tumor” (31), “Pancreatic Neuroendocrine Tumors” (12), and “Rectal Neuroendocrine Tumor” (5). The registry filed 41 of them under no condition at all, and the others under other conditions only, most often Adenoma, Islet Cell (41) and Pancreatic Neoplasms (17).
- −219Match it another way48 name it in the title, 2 in a keyword, and 169 by a synonym or other text the search reads.
- 541The count on this page
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Who runs them
National Cancer Institute (NCI) (20) · Ipsen (17) · Novartis Pharmaceuticals (14) · Grupo Espanol de Tumores Neuroendocrinos (11) · University Medical Center Groningen (10) · Peking Union Medical College Hospital (10) · Memorial Sloan Kettering Cancer Center (9) · European Institute of Oncology (8)
What is being tested here
Drugs under test in Neuroendocrine Tumors studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 11 open · Immune checkpoint inhibitors 4 open · Antimetabolites 4 open · PARP inhibitors 4 open · Alkylating agents 3 open
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- Dec 2026Study of RYZ101 Compared With SOC in Pts w Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy · Phase 3 · RayzeBio, Inc.
- Jan 2027Absorbed Tumor Dose in Peptide Receptor Radionuclide Therapy with Long-acting Somatostatin Analogues - ATSA Trial · Phase 3 · The Netherlands Cancer Institute
- Jun 2027Lutetium 177Lu-Edotreotide Versus Best Standard of Care in Well-differentiated Aggressive Grade-2 and Grade-3 GastroEnteroPancreatic NeuroEndocrine Tumors (GEP-NETs) - COMPOSE · Phase 3 · ITM Solucin GmbH
- Aug 2027Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen · Phase 3 · Crinetics Pharmaceuticals Inc.
- Aug 2027PRRT Versus PRRT Plus Chemotherapy in GEP NET (PReCedeNT Trial) · Phase 3 · Tata Memorial Hospital
- Sep 2027A Phase 3 Study of Ersodetug in Patients With Tumor Hyperinsulinism · Phase 3 · Rezolute
- Nov 2026Immunotherapy Adjuvant Trial in Patients With Stage I-III Merkel Cell Carcinoma · Melanoma and Skin Cancer Trials Limited
- Dec 2026Lesion-to-lesion Comparison of 68Ga-HA-DOTATATE, 18F-DOPA, and 18F-FDG PET/CT in the Evaluation of Metastatic Neuroendocrine Tumors · University of Alberta
- Dec 2026Targeted Therapy and Avelumab in Merkel Cell Carcinoma · Melanoma and Skin Cancer Trials Limited
- Dec 2026Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine Tumors · Fox Chase Cancer Center
Who these studies take
Of the 112 Neuroendocrine Tumors studies recruiting now, 73 (65%) set no upper age limit and 17 (15%) stop at 75 or younger. 12 (11%) take children under 18. 1 (1%) are for women only and 0 (0%) for men only; 4 (4%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 9 (8%) | 8 (7%) |
| 18 | 109 (97%) | 108 (96%) |
| 30 | 110 (98%) | 109 (97%) |
| 40 | 109 (97%) | 108 (96%) |
| 50 | 109 (97%) | 108 (96%) |
| 65 | 107 (96%) | 106 (95%) |
| 75 | 103 (92%) | 102 (91%) |
| 85 | 87 (78%) | 86 (77%) |
Across all 542 studies, recruiting or not: 8% stop at 75 or younger and 2% at 65; 11% take children; <1% are for women only and <1% for men only; 4% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Neuroendocrine Tumors studies take
Of 98 phase 2 interventional studies under Neuroendocrine Tumors, half reached primary completion within 65 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 1 | 54 mo37–75 · 54 studies | — | — |
| Phase 1/2 | 84 mo52–122 · 29 studies | — | — |
| Phase 2 | 65 mo42–88 · 98 studies | — | 60 mo43–83 · 85 studies |
| Phase 3 | 51 mo39–85 · 25 studies | — | — |
| Interventional, no phase | 56 mo43–102 · 35 studies | — | — |
| Observational | 60 mo37–239 · 54 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 15, 2026.
Started recruiting4
- PET/CT Imaging Study With Simultaneous Dual-nuclide Imaging TechniqueNov 10, 2026NCT06914427
- Study of CTX-471 in Patients With Neural Cell Adhesion Molecule (NCAM) Positive Neuroendocrine NeoplasmsNov 9, 2026NCT07684170
- Somatostatin Analogues vs. Observation After Peptide Receptor Radionuclide Therapy (PRRT) in Nonfunctional Neuroendocrine NeoplasmsNov 6, 2026NCT07842172
- A Pilot Study of Total-body PET Using FDA-approved Radiotracers Beyond 18F-FDGOct 27, 2026NCT05160480
Results posted1
Newly registered3
- Liver Transplantation Versus Conventional Medical Therapy for Low-Grade GEP-NET With Liver MetastasesNov 3, 2026NCT07913113
- Multicenter Study for External Validation of the TB-NET ScoreOct 29, 2026NCT07903532
- A Phase 1 Study of IM-1340 in Participants With Advanced CancerOct 22, 2026NCT07890246
Studies
Recruiting first, then most recently updated. Showing 50 of 542. Browse all 542 → or search them.
- A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-KitRecruitingNCT06805825Phase 11 country
- A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityRecruitingNCT06406465Phase 21 country
- Virtual Reality for GI Cancer Pain to Improve Patient Reported OutcomesRecruitingNCT04907643Not applicable1 country
- Lutathera and ASTX727 in Neuroendocrine TumoursRecruitingNCT05178693Phase 11 country
- Tissue Procurement and Natural History Study of Neuroendocrine Neoplasms (NENs) Including Adrenocortical Carcinoma (ACC)RecruitingNCT052379341 country
- Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch StudiesEnrolling by invitationNCT009230261 country
- Multicenter Study for External Validation of the TB-NET ScoreRecruitingNCT079035329 countries
- Clinico-biological Database in Patients Treated With Metabolic Radiotherapy in the Nuclear Medicine DepartmentRecruitingNCT04104529Not applicable1 country
- Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine TumoursRecruitingNCT06345079Phase 22 countries
- PET/CT Imaging Study With Simultaneous Dual-nuclide Imaging TechniqueRecruitingNCT06914427Not applicable1 country
- A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath TumorsRecruitingNCT06041516Phase 11 country
- Study of CTX-471 in Patients With Neural Cell Adhesion Molecule (NCAM) Positive Neuroendocrine NeoplasmsRecruitingNCT07684170Phase 21 country
- Somatostatin Analogues vs. Observation After Peptide Receptor Radionuclide Therapy (PRRT) in Nonfunctional Neuroendocrine NeoplasmsRecruitingNCT07842172Phase 31 country
- Liver Transplantation Versus Conventional Medical Therapy for Low-Grade GEP-NET With Liver MetastasesEnrolling by invitationNCT079131131 country
- Study of RYZ401 in Subjects With Solid Tumors Expressing SSTRs.RecruitingNCT07165132Phase 12 countries
- A Study of BL-M14D1 in Patients With Locally Advanced or Metastatic Small Cell Lung Cancer, Neuroendocrine Tumors and Other Solid TumorsRecruitingNCT06505824Phase 11 country
- Zanzalintinib Versus Everolimus in Participants With Locally Advanced or Metastatic Neuroendocrine TumorsRecruitingNCT06943755Phase 2/318 countries
- Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Neoantigens in People With Metastatic CancerRecruitingNCT03412877Phase 21 country
- A Pilot Study of Total-body PET Using FDA-approved Radiotracers Beyond 18F-FDGRecruitingNCT051604801 country
- Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive TumorsRecruitingNCT06441331Phase 13 countries
- Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ ParagangliomaRecruitingNCT03206060Phase 21 country
- A Phase 1 Study of IM-1340 in Participants With Advanced CancerNot yet recruitingNCT07890246Phase 1
- TheraSphere Japan Pre-Market StudyRecruitingNCT07377487Not applicable1 country
- Natural History and Management of Von Hippel-Lindau (VHL) Associated Pancreatic Neuroendocrine TumorsRecruitingNCT04074135Phase 21 country
- Lu-177-DOTATATE (Lutathera) in Combination With Olaparib in Inoperable Gastroenteropancreatico Neuroendocrine Tumors (GEP-NET)RecruitingNCT04086485Phase 1/21 country
- Zanzalintinib Maintenance in Patients With High Grade Neuroendocrine Neoplasms (HG-NENs)RecruitingNCT06926634Phase 21 country
- Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive TumorsRecruitingNCT05636618Phase 1/21 country
- CapTemY90 for Grade 2/3 NET Liver MetastasesRecruitingNCT04339036Phase 21 country
- Intermediate-Size Cohort EAP for Ersodetug in Patients With Inadequately Controlled Hypoglycemia Related to a TumorAvailableNCT072629701 country
- 211At-MABG in Adults With Advanced Neuroendocrine CancersNot yet recruitingNCT07661420Phase 11 country
- A Comparison of [68Ga]DOTATATE and [18F]AmBF3TATE for the Staging and Assessment of Neuroendocrine MalignanciesNot yet recruitingNCT076211461 country
- Study of Cabozantinib in Participants With Neuroendocrine Tumors Who Have Already Received Prior TreatmentRecruitingNCT073141642 countries
- A Phase 3 Study of Ersodetug in Patients With Tumor HyperinsulinismRecruitingNCT06881992Phase 35 countries
- Comparing DLL3 PET/CT to Standard Scans in Neuroendocrine CancerRecruitingNCT07733024Phase 21 country
- Randomized Interval Assessment Trial of Lu177-Dotatate in Slowly Progressive G1-2 Advanced Midgut Neuroendocrine TumorsRecruitingNCT06878664Phase 32 countries
- EQUITY GI: A Prospective Study to Enhance Quality, Inclusivity, and Trial Participation in Black Patients With Gastrointestinal Cancer.RecruitingNCT06263088Not applicable1 country
- Iconographic Registry of Pancreatobiliary Endoscopy ProceduresRecruitingNCT063445071 country
- Project: Every Child for Younger Patients With CancerRecruitingNCT024022446 countries
- Study of Zanzalintinib in Children and Adolescents With Relapsed or Refractory Solid TumorsNot yet recruitingNCT07773454Phase 1
- The Use of Guarana to Treat Fatigue in Patients With Neuroendocrine Tumors and Gynecologic Cancers (Guarana Fatigue)RecruitingNCT07151391Phase 21 country
- TARGETed Therapy Drug MONITOring in DIGestive OncologyRecruitingNCT05443087Not applicable1 country
- An Investigational Scan ([68Ga] Ga-FAPI-04 PET/CT) for the Imaging of Patients With High-Grade Neuroendocrine CancerRecruitingNCT07132645Early Phase 11 country
- Trial of an Alternative Cabozantinib Dosing Schedule in Metastatic Renal Cell Carcinoma and Neuroendocrine TumorsRecruitingNCT05263050Phase 21 country
- An Open, Single-center Clinical Study of Surufatinib Combined With Temozolomide and S-1 in the First-line Treatment of Advanced Neuroendocrine TumorsRecruitingNCT06038461Phase 1/21 country
- Atezolizumab Plus Tivozanib in Immunologically Cold Tumor TypesRecruitingNCT05000294Phase 1/21 country
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT020126991 country
- Safety, Tolerability and Preliminary Efficacy of NEUK203-13 in Refractory Neuroendocrine Tumor PatientsRecruitingNCT07366658Phase 11 country
- Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative DiseasesRecruitingNCT06788886Not applicable1 country
- Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).RecruitingNCT06607692Phase 1/21 country
- Assessment of Retreatment With Lutathera® in Patients With New Progression of Intestinal Well-differenciated NETRecruitingNCT04954820Phase 21 country