Drug
Atovaquone clinical trials
Also written Mepron.
- studies test it
- 20
- open now
- 3
- in phase 3
- 3
- first study started
- 2004
Keep track of what changes. Save the Atovaquone studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Brand
Combined with it in one product
Studies by the year they started
12 studies that test it; most in 2020 (3)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2007 | 1 |
| 2012 | 1 |
| 2016 | 1 |
| 2018 | 1 |
| 2020 | 3 |
| 2021 | 1 |
| 2023 | 1 |
| 2025 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Early Phase 1
- 2
- Phase 1
- 5
- Phase 2
- 6
- Phase 3
- 3
- Phase 4
- 2
- No phase
- 3
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 6 · Other 14
National Institute of Allergy and Infectious Diseases (NIAID) (4) · Glaxo Wellcome (4) · University of Oxford (2) · Emory University (2) · Baylor College of Medicine (1) · Medicines for Malaria Venture (1) · University of Texas Southwestern Medical Center (1) · Radboud University Medical Center (1)
Often tested with
Tested in the same studies.
Proguanil (4) · Azithromycin (3) · Dapsone (1) · Sulfadiazine (1) · Pyrimethamine (1) · Chloroquine (1) · Clindamycin (1) · Primaquine (1)
Studies
Open first, then newest update. How each study uses Atovaquone is read from its arms, and is right about nine times in ten.
Testing it · 20
- Repurposing Atovaquone for the Treatment of Platinum-Resistant Ovarian CancerRecruitingPhase 2Emory UniversityNCT05998135Written as Atovaquone
- Atovaquone Combined With Radiation in Children With Malignant Brain TumorsRecruitingPhase 1Emory UniversityNCT06624371Written as Atovaquone
- Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives)Not yet recruitingPhase 4McGill University Health Centre/Research Institute of the McGill University Health CentreNCT07357103Written as Atovaquone
- Atovaquone and Azithromycin Combination for Confirmed COVID-19 InfectionTerminatedPhase 2HonorHealth Research InstituteNCT04339426Written as Atovaquone/Azithromycin
- Atovaquone (Mepron®) Combined With Conventional Chemotherapy for de Novo Acute Myeloid Leukemia (AML)CompletedEarly Phase 1Baylor College of MedicineNCT03568994Written as Atovaquone
- Atovaquone With Radical ChemorADIotherapy in Locally Advanced NSCLCCompletedPhase 1University of OxfordNCT04648033Written as Atovaquone Oral Suspension
- Atoguanil BA StudyCompletedPhase 1Medicines for Malaria VentureNCT04866602Written as Atoguanil
- Atovaquone for Treatment of COVID-19CompletedPhase 2University of Texas Southwestern Medical CenterNCT04456153Written as Experimental Group
- A Randomized, Comparative Study of Daily Dapsone and Daily Atovaquone for Prophylaxis Against PCP in HIV-Infected Patients Who Are Intolerant of Trimethoprim and/or SulfonamidesCompletedPhase 3National Institute of Allergy and Infectious Diseases (NIAID)NCT00000802Written as Atovaquone
- A Study to Compare Different Drugs Used to Prevent Serious Bacterial Infections in HIV-Positive ChildrenCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000811Written as Atovaquone
- Phase I Safety and Pharmacokinetics Study of Microparticulate Atovaquone (m-Atovaquone; 566C80) in HIV-Infected and Perinatally Exposed Infants and ChildrenCompletedPhase 1National Institute of Allergy and Infectious Diseases (NIAID)NCT00000773Written as Atovaquone
- Phase II Randomized Open-Label Trial of Atovaquone Plus Pyrimethamine and Atovaquone Plus Sulfadiazine for the Treatment of Acute Toxoplasmic EncephalitisCompletedPhase 2National Institute of Allergy and Infectious Diseases (NIAID)NCT00000794Written as Atovaquone
- Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected PatientsCompletedPhase 4Radboud University Medical CenterNCT00421473Written as Atovaquone / Proguanil
- Atovaquone as Tumour HypOxia ModifierCompletedEarly Phase 1University of OxfordNCT02628080Written as Atovaquone
- Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone SuspensionCompletedPhase 1GlaxoSmithKlineNCT01858831Written as Atovaquone/proguanil HCL
- Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South AmericaCompletedPhase 2/3PfizerNCT00084227Written as Atovaquone/Proguanil
- A Treatment IND for 566C80 Therapy of Pneumocystis Carinii PneumoniaCompletedNot applicableGlaxo WellcomeNCT00001991Written as Atovaquone
- A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-SulfadiazineCompletedNot applicableGlaxo WellcomeNCT00001994Written as Atovaquone
- A Comparison of Atovaquone and Pentamidine in the Prevention of Pneumocystis Carinii Pneumonia in HIV-Infected Patients Who Cannot Take TMP/SMXCompletedPhase 3Glaxo WellcomeNCT00002340Written as Atovaquone
- An Open-Label, Uncontrolled Clinical Trial of Oral 566C80 for the Treatment of Patients With Severe PCP Who Are Intolerant and/or Unresponsive to Therapy With Trimethoprim/Sulfamethoxazole and Parenteral PentamidineCompletedNot applicableGlaxo WellcomeNCT00001990Written as Atovaquone
Given in every arm · 4 — Atovaquone is usual care beside what is tested
- A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)CompletedPhase 1Merck Sharp & Dohme LLCNCT06294912Written as Atovaquone/proguanil
- Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis.CompletedPhase 4State University of New York - Upstate Medical UniversityNCT02564471Written as Atovaquone and Proguanil
- Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous InfectionCompletedNot applicableRadboud University Medical CenterNCT02098590Written as atovaquone/proguanil
- Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under ChemoprophylaxisCompletedNot applicableRadboud University Medical CenterNCT02080026Written as atovaquone/proguanil
Codes
What other systems call Atovaquone · ClinicalTrials.gg INT008891
- MeSH (NLM) D053626AtovaquoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) Y883P1Z2LTATOVAQUONEConfirmed FDA, NLM, Wikidata
- RxNorm 60212Confirmed FDA, Wikidata
- Wikidata Q418179atovaquoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C28838AtovaquoneOne source FDA
- DrugBank DB01117One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D053626 | Atovaquone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | Y883P1Z2LT | ATOVAQUONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 60212 | — | Confirmed FDA, Wikidata |
| Wikidata | Q418179 | atovaquone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C28838 | Atovaquone | One source FDA |
| DrugBank | DB01117 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.