DrugSupplement
Proguanil clinical trials
- studies test it
- 8
- open now
- 0
- in phase 3
- 1
- first study started
- 2004
How studies write it
Studies that test it under each name
Studies by the year they started
8 studies that test it; most in 2012 (2)
| Year | Studies |
|---|---|
| 2004 | 1 |
| 2007 | 1 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 1 |
| 2018 | 1 |
| 2021 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 5
- Phase 2
- 3
- Phase 3
- 1
- Phase 4
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 2 · Other 6
Lagos State University (2) · Duke University (1) · Medicines for Malaria Venture (1) · Radboud University Medical Center (1) · GlaxoSmithKline (1) · University of Southern Denmark (1) · Pfizer (1)
Often tested with
Tested in the same studies.
Atovaquone (4) · Folic Acid (2) · Sorghum grain (2) · Sorghum bicolor Supplement (2) · Artenimol (1) · Piperaquine (1) · Clopidogrel (1) · Azithromycin (1)
Studies
Open first, then newest update. How each study uses Proguanil is read from its arms, and is right about nine times in ten.
Testing it · 8
- Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE)CompletedPhase 4Duke UniversityNCT03178643Written as Proguanil Oral Tablet
- Atoguanil BA StudyCompletedPhase 1Medicines for Malaria VentureNCT04866602Written as Atoguanil
- Drug Interaction Study Between Atovaquone and Antiretroviral Agents in HIV-1 Infected PatientsCompletedPhase 4Radboud University Medical CenterNCT00421473Written as Atovaquone / Proguanil
- Single Oral Dose Study of Atovaquone/Proguanil Hydrochloride Combination Tablets and Atovaquone SuspensionCompletedPhase 1GlaxoSmithKlineNCT01858831Written as Atovaquone/proguanil HCL
- Impact of CYP2C19*17 on the Pharmacokinetics of Proguanil and ClopidogrelCompletedPhase 1University of Southern DenmarkNCT01456546Written as Proguanil
- Quality of Life Study for Sickle Cell Patients Treated With Jobelyn (Sorghum Bicolor Extract)Status unknownPhase 1/2Lagos State UniversityNCT01704794Written as Folic Acid + Paludrine + Jobelyn (500mg)
- The Efficacy of Jobelyn (Sorghum Bicolor Extract)in the Treatment of Sickle Cell AnemiaCompletedPhase 1/2Lagos State UniversityNCT01703104Written as Paludrine + Folic Acid
- Azithromycin Plus Chloroquine Versus Atovaquone-Proguanil For The Treatment Of Uncomplicated Plasmodium Falciparum Malaria In South AmericaCompletedPhase 2/3PfizerNCT00084227Written as Atovaquone/Proguanil
Given in every arm · 4 — Proguanil is usual care beside what is tested
- A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)CompletedPhase 1Merck Sharp & Dohme LLCNCT06294912Written as Atovaquone/proguanil
- Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis.CompletedPhase 4State University of New York - Upstate Medical UniversityNCT02564471Written as Atovaquone and Proguanil
- Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous InfectionCompletedNot applicableRadboud University Medical CenterNCT02098590Written as atovaquone/proguanil
- Target Antigens Induced by Plasmodium Falciparum Sporozoite Immunization Under ChemoprophylaxisCompletedNot applicableRadboud University Medical CenterNCT02080026Written as atovaquone/proguanil
As the comparator · 1 — what is tested is compared with Proguanil
Codes
What other systems call Proguanil · ClinicalTrials.gg INT007199
- MeSH (NLM) D002727ProguanilConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) S61K3P7B2VPROGUANILConfirmed FDA, NLM, Wikidata
- RxNorm 2382Confirmed FDA, Wikidata
- Wikidata Q420607proguanilConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61907ProguanilOne source FDA
- DrugBank DB01131One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D002727 | Proguanil | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | S61K3P7B2V | PROGUANIL | Confirmed FDA, NLM, Wikidata |
| RxNorm | 2382 | — | Confirmed FDA, Wikidata |
| Wikidata | Q420607 | proguanil | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61907 | Proguanil | One source FDA |
| DrugBank | DB01131 | — | One source Wikidata |
Also registered as proguanil hydrochloride (UNII R71Y86M0WT · RxNorm 142428).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.