Drug
Primaquine clinical trials
- studies test it
- 59
- open now
- 3
- in phase 3
- 13
- first study started
- 2001
Keep track of what changes. Save the Primaquine studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
- PQ
- 2
Studies by the year they started
57 studies that test it; most in 2021 (6)
| Year | Studies |
|---|---|
| 2001 | 1 |
| 2003 | 1 |
| 2004 | 1 |
| 2008 | 1 |
| 2009 | 3 |
| 2010 | 3 |
| 2011 | 4 |
| 2012 | 3 |
| 2013 | 3 |
| 2014 | 5 |
| 2015 | 3 |
| 2016 | 3 |
| 2017 | 3 |
| 2018 | 3 |
| 2019 | 4 |
| 2020 | 1 |
| 2021 | 6 |
| 2022 | 4 |
| 2023 | 1 |
| 2024 | 2 |
| 2026 | 2 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 10
- Phase 2
- 12
- Phase 3
- 13
- Phase 4
- 20
- No phase
- 9
What it is tested for
Each study’s main condition, where its own words name it.
- Malaria
- 15
Who runs them
Industry 2 · Other 57
University of Oxford (13) · London School of Hygiene and Tropical Medicine (8) · Menzies School of Health Research (6) · University of California, San Francisco (3) · Centers for Disease Control and Prevention (3) · Fundação de Medicina Tropical Dr. Heitor Vieira Dourado (2) · PATH (2) · National Institute of Allergy and Infectious Diseases (NIAID) (2)
Often tested with
Tested in the same studies.
Chloroquine (10) · Tafenoquine (7) · Artemether, Lumefantrine Drug Combination (7) · Piperaquine (5) · Artenimol (4) · Amodiaquine (3) · Fanasil, pyrimethamine drug combination (3) · Clindamycin (3)
Studies
Open first, then newest update. How each study uses Primaquine is read from its arms, and is right about nine times in ten.
Testing it · 59
- Postpartum 8-aminoquinoline Breast Milk StudyNot yet recruitingPhase 2/3Curtin UniversityNCT07060404Written as Daily primaquine (0.5 mg/kg per day) for 14 days given with food food and water
- Positioning Second-line Therapies for Pneumocystis Jirovecii Pneumonia (PCP Alternatives)Not yet recruitingPhase 4McGill University Health Centre/Research Institute of the McGill University Health CentreNCT07357103Written as Clindamycin + primaquine
- A Revised Tafenoquine Dose to Improve Radical Cure for Vivax MalariaRecruitingPhase 3Menzies School of Health ResearchNCT06148792Written as Primaquine
- Rigorous Assessment of P. Vivax Relapses and Primaquine Efficacy for Radical CureCompletedPhase 4University of Maryland, BaltimoreNCT04706130Written as Primaquine
- Postpartum Primaquine in Breast MilkCompletedPhase 4University of OxfordNCT06191458Written as Primaquine
- Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient PatientsCompletedPhase 2Fundação de Medicina Tropical Dr. Heitor Vieira DouradoNCT03529396Written as Primaquine
- Study to Evaluate Primaquine for Radical Cure of Uncomplicated Plasmodium Vivax Malaria in ChildrenCompletedPhase 2Fundação de Medicina Tropical Dr. Heitor Vieira DouradoNCT05044637Written as Primaquine
- Effectiveness of Novel Approaches to Radical Cure With Tafenoquine and PrimaquineCompletedPhase 3Menzies School of Health ResearchNCT04411836Written as Primaquine
- Gametocytocidal and Transmission-blocking Efficacy of ASAQ and ALAQ With or Without PQ in MaliCompletedPhase 2London School of Hygiene and Tropical MedicineNCT05550909Written as Primaquine Phosphate
- Short Course Radical Cure of P. Vivax Malaria in NepalCompletedPhase 4Menzies School of Health ResearchNCT04079621Written as primaquine
- Study of Malaria Vaccine RTS,S/AS01E in Plasmodium Falciparum-infected and Uninfected Adults Pre-treated With Anti-malarial TherapyCompletedPhase 2PATHNCT04661579Written as Primaquine
- Mass Drug Administration of Dihydroartemisinin-piperaquine + Single Low-dose Primaquine to Accelerate Toward Elimination ActivitiesCompletedNot applicableUniversity of California, San FranciscoNCT04864444Written as Primaquine
- Controlled Human Malaria Infection Transmission Model - Phase ASuspendedPhase 1/2University of OxfordNCT04280692Written as Primaquine
- Tafenoquine and Primaquine in Colostrum and Breast MilkWithdrawnPhase 4University of OxfordNCT04984759Written as Primaquine
- Reducing the Risk of P. Vivax After Falciparum Infections in Co-endemic AreasCompletedPhase 4Menzies School of Health ResearchNCT03916003Written as primaquine
- Therapeutic Efficacy of Chloroquine Plus Primaquine in the Treatment of Uncomplicated Plasmodium VivaxCompletedPhase 4Dinka DugassaNCT06044805Written as Primaquine
- Momordica Charantia and Dihydroartemisinin-piperaquined-primaquine for Uncomplicated Plasmodium Falciparum Malaria Patients in Southwest Sumba RegencyCompletedPhase 2Syamsudin Abdillah,Ph.D, Pharm DNCT05829187Written as Primaquine
- Single Low-dose Primaquine Efficacy and Safety.CompletedPhase 4Tropical Pesticides Research Institute, TanzaniaNCT03352843Written as Primaquine
- Incidence of Vivax Along the Thai Burma BorderCompletedNot applicableUniversity of OxfordNCT01076868Written as Primaquine
- Gametocytocidal and Transmission-blocking Efficacy of PQ in Combination With AL and TQ in Combination With SPAQ in MaliCompletedPhase 2London School of Hygiene and Tropical MedicineNCT05081089Written as Primaquine Phosphate
See all 59 studies that test Primaquine →
Given in every arm · 6 — Primaquine is usual care beside what is tested
- A Study to Evaluate Antimalarial Activity and Safety of MK-7602 in Healthy Adults (MK-7602-003)CompletedPhase 1Merck Sharp & Dohme LLCNCT06294912Written as Primaquine
- A Study to Assess Safety of Current Standard Malaria Treatment and an Assessment of G6PD Status in South-east BangladeshCompletedPhase 4Menzies School of Health ResearchNCT02389374Written as Primaquine
- Combination Momordica Charantia Extract and Primaquine Againts Plasmodium Falciparum Uncomplicated and Plasmodium Vivax Uncomplicated Treatment in Manokwari, West PapuaCompletedPhase 2Syamsudin Abdillah,Ph.D, Pharm DNCT06036030Written as Primaquine
- Malaria Elimination Pilot Study in Military Forces in CambodiaStatus unknownPhase 4Armed Forces Research Institute of Medical Sciences, ThailandNCT02653898Written as Primaquine
- Effect of ACT-451840 Against Early Plasmodium Falciparum Blood Stage Infection in Healthy SubjectsCompletedPhase 1Idorsia Pharmaceuticals Ltd.NCT02223871Written as Primaquine:
- P. Knowlesi Trial of Artesunate-mefloquine Versus ChloroquineCompletedPhase 3Menzies School of Health ResearchNCT01708876Written as Primaquine
As the comparator · 9 — what is tested is compared with Primaquine
- Southeast Asia Dose Optimization of TafenoquineRecruitingPhase 4University of OxfordNCT04704999Written as Primaquine
- An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and OlderRecruitingPhase 3GlaxoSmithKlineNCT06666491Written as Primaquine
- Efficacy and Safety Study of Tafenoquine (TQ) Co-administered With Dihydroartemisinin-piperaquine (DHA-PQP) for the Radical Cure of Plasmodium Vivax (P. Vivax) MalariaCompletedPhase 3GlaxoSmithKlineNCT02802501Written as Primaquine
- Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking AgentCompletedPhase 1/2Medicines for Malaria VentureNCT02431650Written as Primaquine
- Methylene Blue Against Falciparum Malaria in Burkina FasoCompletedPhase 2Heidelberg UniversityNCT02851108Written as Primaquine
- Metabolism and Pharmacokinetics of Primaquine Enantiomers in Human Volunteers Receiving a Seven Day Dose RegimenCompletedPhase 1University of Mississippi, OxfordNCT03934450Written as Primaquine Phosphate
- Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax RelapseCompletedPhase 2GlaxoSmithKlineNCT01376167Written as Primaquine 15mg
- Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in AdultsTerminatedPhase 2U.S. Army Medical Research and Development CommandNCT01290601Written as Chloroquine + Primaquine
- Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax InfectionCompletedPhase 2/3Oswaldo Cruz FoundationNCT02691910Written as Primaquine
Codes
What other systems call Primaquine · ClinicalTrials.gg INT008088
- MeSH (NLM) D011319PrimaquineConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) MVR3634GX1PRIMAQUINEConfirmed FDA, NLM, Wikidata
- RxNorm 8687Confirmed FDA, Wikidata
- Wikidata Q419834(RS)-primaquineConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C62071PrimaquineOne source FDA
- DrugBank DB01087One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D011319 | Primaquine | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | MVR3634GX1 | PRIMAQUINE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 8687 | — | Confirmed FDA, Wikidata |
| Wikidata | Q419834 | (RS)-primaquine | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C62071 | Primaquine | One source FDA |
| DrugBank | DB01087 | — | One source Wikidata |
Also registered as primaquine phosphate (UNII H0982HF78B · RxNorm 8689).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.