Toxoplasmosis clinical trials
The registry lists 29 studies for Toxoplasmosis across more than 10 countries. 8 are recruiting or about to start. 17 of them are mainly about Toxoplasmosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-01-16.
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Who runs them
National Institute of Allergy and Infectious Diseases (NIAID) (6) · Sohag University (4) · University Hospital, Clermont-Ferrand (1) · Singh, Ranjan Kumar, M.D. (1) · Shahid Beheshti University of Medical Sciences (1) · Palo Alto Medical Foundation (1) · Nicolaus Copernicus University (1) · Benha University (1)
What is being tested here
Drugs under test in Toxoplasmosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pyrimethamine | 1 | 0 | 6 |
| Leucovorin | 1 | 0 | 1 |
| Sulfadiazine | 1 | 0 | 1 |
| Clindamycin | 0 | 1 | 2 |
| Zidovudine | 0 | 1 | 1 |
| Valproic Acid | 0 | 0 | 1 |
| Azithromycin | 0 | 0 | 1 |
| Atovaquone | 0 | 0 | 1 |
| Dexamethasone | 0 | 1 | 1 |
Who these studies take
Of the 4 Toxoplasmosis studies recruiting now, 2 (50%) set no upper age limit and 1 (25%) stop at 75 or younger. 2 (50%) take children under 18. 1 (25%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 2 (50%) | 2 (50%) |
| 18 | 4 (100%) | 3 (75%) |
| 30 | 4 (100%) | 3 (75%) |
| 40 | 4 (100%) | 3 (75%) |
| 50 | 4 (100%) | 3 (75%) |
| 65 | 3 (75%) | 3 (75%) |
| 75 | 3 (75%) | 3 (75%) |
| 85 | 3 (75%) | 3 (75%) |
Across all 29 studies, recruiting or not: 31% stop at 75 or younger and 24% at 65; 62% take children; 10% are for women only and 3% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 29 of 29. search them.
- Role of Circulating MicroRNAs in Differentiating Psychological Disorders Among Women With Chronic ToxoplasmosisRecruitingNCT073468331 country
- Isolated Positive Toxoplasma Gondii PCR in BloodNot yet recruitingNCT070549181 country
- Toxoplasma Gondii Seroprevalence Among Children With Some Neuropsychiatric DisordersNot yet recruitingNCT069802981 country
- Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR DiagnosisRecruitingNCT063054681 country
- Toxoplasma Gondii Infection in Both Children and Adult Patients With Hematological MalignanciesNot yet recruitingNCT05963295Not applicable1 country
- Measuring the Prevalence of Toxoplasmosis and Its Socio-economic ConsequencesNot yet recruitingNCT05860998
- Lyon Cohort of Maternal and Congenital Toxoplasma InfectionsRecruitingNCT029369211 country
- Pyrimethamine, Sulfadiazine, and Leucovorin in Treating Patients With Congenital ToxoplasmosisRecruitingNCT00004317Phase 41 country
- Analysis of Cerebrospinal Fluid in Patients With Cerebral Toxoplasmosis at CHSD (2004-2024)CompletedNCT070440371 country
- Diagnosis of Toxoplasma Gondii Infection by Exploration of Cellular Immunity (TOXCELL)CompletedNCT04825600Not applicable1 country
- Latent Toxoplasmosis in Females With Borderline Personality DisorderWithdrawnNCT039326561 country
- Evaluation of the Role of Latent Toxoplasmosis in Female Patients With Active Acne VulgarisStatus unknownNCT05783778Not applicable
- Genetic Diversity of Toxoplasma Gondii in Cancer PatientsStatus unknownNCT048340761 country
- A Study of Pyrimethamine in the Treatment of Infection by a Certain Parasite in HIV-Positive PatientsCompletedNCT00000973Phase 11 country
- A Study of Three Drugs Plus Zidovudine in the Prevention of Infections in HIV-Infected PatientsCompletedNCT00000991Phase 32 countries
- Primary Prophylaxis of Cerebral Toxoplasmosis in HIV-Infected PatientsCompletedNCT00000643Phase 21 country
- Determination of Genetic Susceptibility in Severe Recurrences of Ocular ToxoplasmosisTerminatedNCT02863588Not applicable1 country
- Phase I Study of Pyrimethamine in Healthy Japanese and Caucasian SubjectsCompletedNCT03258762Phase 11 country
- Intestinal Parasites in Inhabitants of Kuyavian-Pomeranian Province in PolandCompletedNCT034904351 country
- Prevalence of HIV +ve Cases With AIDS Defining Opportunistic Infections Among ART Naive Patients Attending ART CentreCompletedNCT039930931 country
- Antiretroviral Drug Interaction Study in Volunteers With HIVCompletedNCT01479361Phase 11 country
- Pilot Trial of Valproate as Adjunctive Treatment for Toxoplasma Gondii Infection in Early Course SchizophreniaCompletedNCT02011750Phase 41 country
- Evaluation of Biological Biomarkers Diagnostic of Toxoplasmosis UveitisCompletedNCT02843438Not applicable1 country
- A Randomized Prospective Study of Pyrimethamine Therapy for Prevention of Toxoplasmic Encephalitis in HIV-Infected Individuals With Serologic Evidence of Latent Toxoplasma Gondii InfectionCompletedNCT00000666Not applicable1 country
- A Pilot Study of Oral Clindamycin and Pyrimethamine for the Treatment of Toxoplasmic Encephalitis in Patients With AIDSCompletedNCT00000674Not applicable1 country
- A Study of Azithromycin Plus Pyrimethamine in the Treatment of a Brain Infection in Patients With AIDSCompletedNCT00000966Phase 11 country
- To Compare Intravitreal Clindamycin & Dexamethasone With Classic Treatment of Toxoplasmic RetinochoroiditisStatus unknownNCT00372294Phase 31 country
- A Pilot Study of 566C80 for the Salvage Treatment of Toxoplasmic Encephalitis in Patients Infected With the Human Immunodeficiency Virus (HIV) Who Have Failed or Are Intolerant of Pyrimethamine-SulfadiazineCompletedNCT00001994Not applicable2 countries
- Toxoplasmic Encephalitis in Patients With AIDS. Treatment and Prevention of RelapseCompletedNCT00002064Not applicable1 country