Alkylating agents: all 3,295 studies that test it

Page 6 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.

• Bendamustine, Obinutuzumab, and Venetoclax in Patients With Untreated Mantle Cell LymphomaActive, not recruitingNCT03872180Phase 2Results posted
• Phase II Study of Bendamustine and Rituximab Plus Venetoclax in Untreated Mantle Cell Lymphoma Over 60 Years of AgeCompletedNCT03834688Phase 2Results posted
• 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation TherapyCompletedNCT03778294Phase 2Results posted
• Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With GlioblastomaCompletedNCT03746080Phase 2Results posted
• Administering Peripheral Blood Lymphocytes Transduced With a Murine T-Cell Receptor Recognizing the G12D Variant of Mutated RAS in HLA-A*11:01 PatientsTerminatedNCT03745326Phase 1/2Results posted
• Gemcitabine, Bendamustine, and Nivolumab in Patients With Relapsed or Refractory Classical Hodgkin LymphomaCompletedNCT03739619Phase 1/2Results posted
• 2-Step Approach to Stem Cell Transplant in Treating Participants With Hematological MalignanciesCompletedNCT03712878Phase 2Results posted
• Brentuximab Vedotin and Nivolumab in Treating Patients With Early Stage Classic Hodgkin LymphomaActive, not recruitingNCT03712202Phase 2Results posted
• Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid TumorsCompletedNCT03709680Phase 2Results posted
• Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBMTerminatedNCT03705351Phase 1Results posted
• Comparing Cyclophosphamide and Abatacept With Standard of Care Treatment Following Stem Cell TransplantationCompletedNCT03680092Phase 2Results posted
• Allogeneic Hematopoietic Cell Transplantation for Disorders of T-cell Proliferation and/or DysregulationActive, not recruitingNCT03663933Phase 2Results posted
• Trial of Mitomycin C During Nephroureterectomy for Urothelial CarcinomaCompletedNCT03658304Phase 2Results posted
• Liver Transplantation With Tregs at UCSFTerminatedNCT03654040Phase 1/2Results posted
• MT2017-45: CAR-T Cell Therapy for Heme MalignanciesActive, not recruitingNCT03642626Phase 2Results posted
• Acalabrutinib With Bendamustine / Rituximab Followed by Cytarabine / Rituximab for Untreated Mantle Cell LymphomaCompletedNCT03623373Phase 2Results posted
• Avelumab in Combination With Fluorouracil and Mitomycin or Cisplatin and Radiation Therapy in Treating Participants With Muscle-Invasive Bladder CancerCompletedNCT03617913Phase 2Results posted
• Donor Stem Cell Transplantation Using α/β+ T-lymphocyte Depleted Grafts From HLA Mismatched DonorsTerminatedNCT03615105Phase 2Results posted
• Bendamustine/Rituximab Followed by Venetoclax and Rituximab for Treatment of Chronic Lymphocytic LeukemiaCompletedNCT03609593Phase 2Results posted
• A Study of the Effect of Blood Stem Cell Transplant After Chemotherapy Alone in Patients With Fanconi AnemiaTerminatedNCT03600909Phase 2Results posted
• Cardiac Safe Transplants for Systemic SclerosisTerminatedNCT03593902Phase 2/3Results posted
• Venetoclax, Carmustine, Etoposide, Cytarabine, and Melphalan Before Stem Cell Transplant in Treating Participants With Relapsed or Refractory Non-Hodgkin LymphomaCompletedNCT03583424Phase 1/2Results posted
• Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 MutationsActive, not recruitingNCT03581292Phase 2Results posted
• A Phase 2b Study of UGN-102 for Low Grade Intermediate Risk Non-Muscle-Invasive Bladder CancerCompletedNCT03558503Phase 2Results posted
• Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)CompletedNCT03556384Phase 2Results posted
• Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation StatusCompletedNCT03519412Phase 2Results posted
• Very Early PET-response Adapted Targeted Therapy for Advanced Hodgkin Lymphoma: a Single -Arm Phase II StudyActive, not recruitingNCT03517137Phase 2Results posted
• A Trial For Participants With Ewing's Sarcoma Treated With Vigil in Combination With Irinotecan and TemozolomideTerminatedNCT03495921Phase 3Results posted
• Haploidentical Allogeneic Peripheral Blood Transplantation: Examining Checkpoint Immune Regulators' ExpressionCompletedNCT03480360Phase 3Results posted
• Nab-sirolimus in Recurrent High Grade Glioma and Newly Diagnosed GlioblastomaCompletedNCT03463265Phase 2Results posted
• Melphalan Hydrochloride in Treating Participants With Newly-Diagnosed Multiple Myeloma Undergoing Donor Stem Cell TransplantationCompletedNCT03417284Phase 1/2Results posted
• Valchlor in the Treatment of Lichen PlanopilarisCompletedNCT03417141Phase 2Results posted
• Mechlorethamine Induced Contact Dermatitis Avoidance StudyCompletedNCT03380026Phase 2Results posted
• Disulfiram and Copper Gluconate With Temozolomide in Unmethylated Glioblastoma MultiformeTerminatedNCT03363659Phase 2Results posted
• Thiotepa Plus Fludarabine+ Melphalan as the Preparative Regime for Alternative Donor TransplantationCompletedNCT03342196Phase 2Results posted
• A Study Comparing Zanubrutinib With Bendamustine Plus Rituximab in Participants With Previously Untreated CLL or SLLActive, not recruitingNCT03336333Phase 3Results posted
• Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood CancerTerminatedNCT03333486Phase 2Results posted
• Doxorubicin Hydrochloride, Pembrolizumab, Vinblastine, and Dacarbazine in Treating Patients With Classical Hodgkin LymphomaCompletedNCT03331341Phase 1/2Results posted
• Neoadjuvant Dose-Dense For Early Her2Neu Positive Breast CancerTerminatedNCT03329378Phase 2Results posted
• Pevonedistat, Irinotecan, and Temozolomide in Treating Patients With Recurrent or Refractory Solid Tumors or LymphomaCompletedNCT03323034Phase 1Results posted
• Study to Evaluate the Safety and Efficacy of KITE-585 in Participants With Relapsed/Refractory Multiple MyelomaTerminatedNCT03318861Phase 1Results posted
• Arsenic Trioxide With Cyclophosphamide in Patients With Relapsed/Refractory Acute Myeloid LeukemiaTerminatedNCT03318016Phase 1Results posted
• Bendamustine + Obinutuzumab Induction With Obinutuzumab Maintenance in Untreated Mantle Cell LymphomaTerminatedNCT03311126Phase 2Results posted
• Allogeneic Stem Cell Transplantation for Multiple Myeloma and MyelofibrosisTerminatedNCT03303950Phase 2Results posted
• Neoadjuvant Carbo/Paclitaxel Followed by Doxorubicin/Cyclophosphamide in Breast CancerCompletedNCT03301350Phase 2Results posted
• Adoptive Cell Therapy Across Cancer DiagnosesCompletedNCT03296137Phase 1/2Results posted
• A Study of Olaratumab (LY3012207), Doxorubicin, and Ifosfamide in Participants With Advanced or Metastatic Soft Tissue SarcomaCompletedNCT03283696Phase 1Results posted
• A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin LymphomasActive, not recruitingNCT03277729Phase 1/2Results posted
• Haploidentical Bone Marrow Transplantation in Sickle Cell Patients (BMTCTN1507)CompletedNCT03263559Phase 2Results posted
• Comparison of Triple GVHD Prophylaxis Regimens for Nonmyeloablative or Reduced Intensity Conditioning Unrelated Mobilized Blood Cell TransplantationTerminatedNCT03246906Phase 2Results posted
• Doxorubicin, Vinblastine, Dacarbazine, Brentuximab Vedotin, and Nivolumab in Treating Patients With Stage I-II Hodgkin LymphomaActive, not recruitingNCT03233347Phase 2Results posted
• Ibrutinib, Rituximab, Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin Hydrochloride in Treating Patients With HIV-Positive Stage II-IV Diffuse Large B-Cell LymphomasActive, not recruitingNCT03220022Phase 1Results posted
• Chemotherapy, Total Body Irradiation, and Post-Transplant Cyclophosphamide in Reducing Rates of Graft Versus Host Disease in Patients With Hematologic Malignancies Undergoing Donor Stem Cell TransplantActive, not recruitingNCT03192397Phase 1/2Results posted
• T-DM1 Alone Versus T-DM1 and Metronomic Temozolomide in Secondary Prevention of HER2-Positive Breast Cancer Brain Metastases Following Stereotactic RadiosurgeryTerminatedNCT03190967Phase 1/2Results posted
• Study of Nonmyeloablative Peripheral Blood Stem Cell Transplant With High-dose Posttransplantation Cyclophosphamide in Hematopoietic Malignancies Including Those That Are Challenging to EngraftTerminatedNCT03187756Phase 2Results posted
• Bendamustine and Melphalan in MyelomaCompletedNCT03187223Phase 2Results posted
• Atezolizumab in Combination With Temozolomide and Radiation Therapy in Treating Patients With Newly Diagnosed GlioblastomaCompletedNCT03174197Phase 1/2Results posted
• Image-Based Quantitative Assessment of Acute Radiation-Induced Changes in GliomaTerminatedNCT03168919Not applicableResults posted
• GVAX Pancreas Vaccine (With CY) in Combination With Nivolumab and SBRT for Patients With Borderline Resectable Pancreatic CancerCompletedNCT03161379Phase 2Results posted
• Propylene Glycol-Free Melphalan HCl (EVOMELA®) in Combination With Fludarabine and Total Body Irradiation Based Reduced Intensity Conditioning for Haploidentical TransplantationCompletedNCT03159702Phase 2Results posted
• Bavituximab With Radiation and Temozolomide for Patients With Newly Diagnosed GlioblastomaCompletedNCT03139916Phase 2Results posted
• Spectroscopic MRI-Guided Radiation Therapy Planning in GlioblastomaCompletedNCT03137888Phase 2Results posted
• BrUOG 329 Onivyde & Metronomic Temozolomide in Recurrent GlioblastomaTerminatedNCT03119064Phase 1/2Results posted
• Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell LymphomaActive, not recruitingNCT03113500Phase 2Results posted
• Umbilical Cord Blood Transplant With Added Sugar and Chemotherapy and Radiation Therapy in Treating Patients With Leukemia or LymphomaCompletedNCT03096782Phase 2Results posted
• Heated Intraperitoneal Chemotherapy and Gastrectomy for Gastric Cancer With Positive Peritoneal CytologyCompletedNCT03092518Phase 2Results posted
• Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell DiseaseActive, not recruitingNCT03077542Phase 1/2Results posted
• TCP Regimen in Newly Diagnosed MCD:a Prospective, Single-center, Single-arm, Phase-II Pilot TrialStatus unknownNCT03043105Phase 2Results posted
• Etoposide, Prednisone, Vincristine Sulfate, Cyclophosphamide, and Doxorubicin in Treating Patients With Acute Lymphoblastic Leukemia or Lymphoblastic LymphomaCompletedNCT03023046Phase 2Results posted
• Laser Interstitial Thermal Therapy and Lomustine in Treating Patients With Recurrent Glioblastoma or Anaplastic AstrocytomaTerminatedNCT03022578Phase 2Results posted
• Calcineurin Inhibitor-Free GVHD Prevention Regimen After Related Haplo PBSCTCompletedNCT03018223Phase 1Results posted
• Nivolumab, Ifosfamide, Carboplatin, and Etoposide as Second-Line Therapy in Treating Patients With Refractory or Relapsed HLActive, not recruitingNCT03016871Phase 2Results posted
• Epacadostat, Pembrolizumab, and CRS-207, With or Without CY/GVAX Pancreas in Patients With Metastatic Pancreas CancerCompletedNCT03006302Phase 2Results posted
• A Study of Durvalumab in Combination With R-CHOP or Lenalidomide Plus R-CHOP in Previously Untreated High-Risk Diffuse Large B-Cell LymphomaCompletedNCT03003520Phase 2Results posted
• Efficacy and Safety of the Cryopreserved Formulation of OTL-101 in Subjects With ADA-SCIDCompletedNCT02999984Phase 1/2Results posted
• Sex-Mismatched Allogeneic Bone Marrow Transplantation for Men With Metastatic Castration-Resistant Prostate CancerTerminatedNCT02995330Phase 1Results posted
• Propylene Glycol-Free Melphalan Hydrochloride (Evomela) in AL Amyloidosis PatientsTerminatedNCT02994784Phase 2Results posted
• A Study of Brentuximab Vedotin + Adriamycin, Vinblastine, and Dacarbazine in Pediatric Participants With Advanced Stage Newly Diagnosed Hodgkin LymphomaActive, not recruitingNCT02979522Phase 1/2Results posted
• Nanoparticle Albumin-Bound Rapamycin, Temozolomide, and Irinotecan Hydrochloride in Treating Pediatric Patients With Recurrent or Refractory Solid TumorsCompletedNCT02975882Phase 1Results posted
• MEtronomic TrEatment Option in Advanced bReast cAncerCompletedNCT02954055Phase 2Results posted
• A Study to Evaluate Dara-CyBorD in Previously Untreated and Relapsed Subjects With Multiple MyelomaCompletedNCT02951819Phase 2Results posted
• Avelumab In Combination Regimens That Include An Immune Agonist, Epigenetic Modulator, CD20 Antagonist and/or Conventional Chemotherapy in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma (R/R DLBCL)TerminatedNCT02951156Phase 3Results posted
• Pre-operative IRX-2 in Early Stage Breast Cancer (ESBC)CompletedNCT02950259Phase 1Results posted
• A Study of Nivolumab Plus Brentuximab Vedotin in Patients Between 5 and 30 Years Old, With Hodgkin's Lymphoma (cHL), Relapsed or Refractory From First Line TreatmentCompletedNCT02927769Phase 2Results posted
• Optimizing Haploidentical Aplastic Anemia Transplantation (BMT CTN 1502)CompletedNCT02918292Phase 2Results posted
• Heated Mitomycin and Cisplatin During Surgery in Treating Patients With Stomach or Gastroesophageal CancerCompletedNCT02891447Phase 2Results posted
• Haploidentical (Half-matched) Related Donor Stem Cell Transplantation Using Killer Immunoglobulin-like Receptors in Addition to Normal Selection Factors to Determine the Best DonorCompletedNCT02880293Not applicableResults posted
• Trial To Test Safety And Efficacy Of Vaccination For Incurable HPV 16-Related Oropharyngeal, Cervical And Anal CancerCompletedNCT02865135Phase 1/2Results posted
• Peptide Targets for Glioblastoma Against Novel Cytomegalovirus AntigensTerminatedNCT02864368Phase 1Results posted
• Bendamustine and Rituximab for the Treatment of Splenic Marginal Zone LymphomaCompletedNCT02853370Phase 2Results posted
• Pembrolizumab, Bevacizumab, and Cyclophosphamide in Treating Patients With Recurrent Ovarian, Fallopian Tube, or Primary Peritoneal CancerCompletedNCT02853318Phase 2Results posted
• NMA Haplo or MUD BMT for Newly Diagnosed Severe Aplastic AnemiaCompletedNCT02833805Phase 2Results posted
• Targeting Microenvironment and Cellular Immunity in Sarcomas Weekly Trabectedin Combined With Metronomic CyclophosphamideCompletedNCT02805725Phase 1/2Results posted
• Ahmed Glaucoma Valve Surgery With Mitomycin-CCompletedNCT02805257Phase 2Results posted
• A Study of High-Dose Chemoradiation Using Biologically-Based Target Volume Definition in Patients With GlioblastomaCompletedNCT02805179Phase 2Results posted
• Gene Therapy in Treating Patients With Human Immunodeficiency Virus-Related Lymphoma Receiving Stem Cell TransplantActive, not recruitingNCT02797470Phase 1/2Results posted
• PD-1 Knockout Engineered T Cells for Metastatic Non-small Cell Lung CancerCompletedNCT02793856Phase 1Results posted
• HLA-Mismatched Unrelated Donor Bone Marrow Transplantation With Post-Transplantation CyclophosphamideCompletedNCT02793544Phase 2Results posted
• The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC StudyCompletedNCT02793128Phase 3Results posted
• High-Risk Neuroblastoma Chemotherapy Without G-CSFCompletedNCT02786719Not applicableResults posted

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