Alkylating agents: all 3,295 studies that test it
Page 4 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.
- Metronomic Temozolomide in Unfit NENs Patients Metronomic Temozolomide in Unfit Patients With Advanced Neuroendocrine Neoplasms (NENs): MeTe StudyRecruitingNCT05554003Phase 2
- Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed MedulloblastomaRecruitingNCT05535166Phase 2
- Study of CAR-T Cell Therapy in the Treatment of Relapsed/Refractory Hematological MalignanciesRecruitingNCT05528887Phase 1
- Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)RecruitingNCT05521984Phase 1
- B-cell Mature Non-Hodgkin's Lymphoma Treatment Protocol in Children and Adolescents 2021RecruitingNCT05518383Phase 4
- Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKDRecruitingNCT05510323Phase 3
- Early Trial of Allogeneic Hematopoietic Stem Cell Transplantation for Patients Who Will Receive a Kidney Transplant From the Same DonorRecruitingNCT05508009Phase 1/2
- A Study to Give Treatment Inside the Eye to Treat RetinoblastomaRecruitingNCT05504291Phase 2
- MMF Versus CYC in the Induction Therapy of Pediatric Active Proliferative LNRecruitingNCT05495893Phase 4
- Safety and Efficacy of Cyclophosphamide, Sorafenib, Bevacizumab, and Atezolizumab in Pediatric Solid Tumor PatientsRecruitingNCT05468359Phase 1/2
- The Lowest Effective Dose of Post-Transplantation Cyclophosphamide in Combination With Sirolimus and Mycophenolate Mofetil as Graft-Versus-Host Disease Prophylaxis After Reduced Intensity Conditioning and Peripheral Blood Stem Cell TransplantationRecruitingNCT05436418Phase 1/2
- A Study for the Adjuvant Treatment of Breast CancerRecruitingNCT05420467Phase 4
- A Study for the Neoadjuvant Treatment of Breast CancerRecruitingNCT05420454Phase 4
- Metronomic Chemotherapy in Wilms Tumor (MetroWilms-1906)RecruitingNCT05384821Phase 1/2
- Donor Lymphocyte Infusion After Allogeneic Hematopoietic Cell Transplantation for High-Risk Hematologic MalignanciesRecruitingNCT05327023Phase 1/2
- Chemotherapy for the Treatment of Patients With Newly Diagnosed Very Low-Risk and Low Risk Fusion Negative RhabdomyosarcomaRecruitingNCT05304585Phase 3
- Allogeneic Hematopoietic Stem Cell Transplantation for 4/M NeuroblastomaNot yet recruitingNCT05303727Phase 2
- Mecapegfilgrastim With Chemotherapy for Peripheral Blood Stem Cell Mobilization in MM and LymphomaRecruitingNCT05294055Phase 2
- Post-Transplant Cyclophosphamide, Bortezomib and Abatacept for the Prevention of Graft-versus-Host-Disease (GvHD)RecruitingNCT05289167Phase 1/2
- Modified Immune Cells (TAG72-CAR T Cells) for the Treatment of Patients With Platinum Resistant Epithelial Ovarian CancerRecruitingNCT05225363Phase 1
- Pembrolizumab, Olaparib, and Temozolomide for People With GliomaRecruitingNCT05188508Phase 2
- Neoadjuvant Treatment Pegylated Liposomal Doxorubicin Plus Cyclophosphamide Sequential Docetaxel Plus Trastuzumab and Pertuzumab Versus Docetaxel Plus Carboplatin Combined With Trastuzumab and Pertuzumab in HER-2 Positive Breast CancerRecruitingNCT05159193Phase 3
- A Study of Zilovertamab Vedotin (MK-2140) in Combination With Standard of Care in Participants With Relapsed or Refractory Diffuse Large B-Cell Lymphoma (rrDLBCL) (MK-2140-003)RecruitingNCT05139017Phase 2/3
- Preoperative Chemoradiotherapy With CApecitabine and Temozolomide in MGMT Silenced, MSS, Locally Advanced RecTal CancerRecruitingNCT05136326Phase 2
- Temozolomide Monotherapy or in Combination With Olaparib in Patients With Triple Negative Breast Cancer (TNBC)Not yet recruitingNCT05128734Phase 2
- The Efficacy of WVI in Patients With Localized Basal Ganglia Intracranial Germ Cell TumorsRecruitingNCT05124951Phase 2
- Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain CancerRecruitingNCT05106296Phase 1
- Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological MalignancesRecruitingNCT05092451Phase 1/2
- Carmustine Wafer in Combination With Retifanlimab and Radiation With/Without Temozolomide in Subjects With GlioblastomaRecruitingNCT05083754Phase 1
- Testing the Use of Chemotherapy After Surgery for High-Risk Pancreatic Neuroendocrine TumorsRecruitingNCT05040360Phase 2
- Two Step Haplo With Radiation ConditioningRecruitingNCT05031897Phase 2
- Preoperative Radiosurgery for the Treatment of High Grade Glioma, NeoGlioma TrialRecruitingNCT05030298Phase 1
- A Phase II Study of Allogeneic Hematopoietic Stem Cell Transplant for Subjects With VEXAS (Vacuoles, E1 Enzyme, X-linked, Autoinflammatory, Somatic) SyndromeRecruitingNCT05027945Phase 2
- GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor MalignanciesRecruitingNCT05003895Phase 1
- Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic MalignanciesRecruitingNCT04959175Phase 1/2
- Oxidative Phosphorylation Targeting In Malignant Glioma Using Metformin Plus Radiotherapy TemozolomideRecruitingNCT04945148Phase 2
- Adjustment of Chemotherapy Duration in Follicular Lymphoma According to Minimal Residual Disease StatusRecruitingNCT04934930Phase 2
- DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell LymphomaRecruitingNCT04920617Phase 2
- Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung CancerRecruitingNCT04919382Phase 2
- Study of PV in Combination With Bendamustine and Rituximab for Patients With R/R MCLNot yet recruitingNCT04913103Phase 2
- Intrathecal Chemotherapy for Central Nervous System Metastasis in RetinoblastomaRecruitingNCT04903678Not applicable
- Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing SarcomaRecruitingNCT04901702Phase 1/2
- A Trial Evaluating the Activity and Safety of Combination Between Cabozantinib and Temozolomide in Lung and GEP-NENS Progressive After Everolimus, Sunitinib or PRRT (CABOTEM)RecruitingNCT04893785Phase 2
- Methods of T Cell Depletion Trial (MoTD)RecruitingNCT04888741Phase 2
- Yttrium-90 Labeled Anti-CD25 Monoclonal Antibody Combined With BEAM Chemotherapy Conditioning for the Treatment of Primary Refractory or Relapsed Hodgkin LymphomaRecruitingNCT04871607Phase 2
- Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent GlioblastomaRecruitingNCT04863950Phase 2
- Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal HistologiesRecruitingNCT04847063Phase 1
- Comparative Study of Mitomycin and Lobaplatin in Advanced Colorectal Cancer Patients With Radical Surgery Combined With Hyperthermic Intraperitoneal ChemotherapyNot yet recruitingNCT04845490Phase 2
- Clinical Study of ssCART-19 Cells in Patients With CD19 Positive Relapsed or Refractory Acute Lymphoblastic LeukemiaRecruitingNCT04825496Phase 1
- Topotecan and Melphalan for RetinoblastomaRecruitingNCT04799002Phase 3
- Sequential Neoadjuvant Chemotherapy in Soft Tissue SarcomaRecruitingNCT04776525Phase 2
- MicroRNA Profiles in Triple Negative Breast CancerRecruitingNCT04771871Phase 2
- Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma PatientsRecruitingNCT04757337Phase 3
- PACIFIC: Primary Mediastinal Large B-cell Lymphoma Treated With Antibody Therapy, Checkpoint Inhibitor in Frontline With ImmunoChemotherapyRecruitingNCT04745949Phase 2
- Different Immunosuppressive Treatment in iMNRecruitingNCT04745728Phase 3
- Rituximab, Lenalidomide Combined With Methotrexate and Temozolomide For Primary Central Nervous System LymphomaRecruitingNCT04737889Phase 2
- Targeting CD19 and CD22 CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory B Cell LymphomaRecruitingNCT04715217Phase 1/2
- Targeting CD19 and BCMA CAR-T Cells Immunotherapy in Patients With Relapsed or Refractory Multiple MyelomaRecruitingNCT04714827Phase 1/2
- Venetoclax to Improve Outcomes of Fractionated Busulfan Regimen in Patients With High-Risk AML and MDSRecruitingNCT04708054Phase 2/3
- 5FU/LV, Irinotecan, Temozolomide and Bevacizumab for MGMT Silenced, Microsatellite Stable Metastatic Colorectal Cancer.RecruitingNCT04689347Phase 1/2
- A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCTRecruitingNCT04684368Phase 2
- IS-free Treg HaploHCTRecruitingNCT04678401Phase 1
- A Multicenter Clinical Study on the Safety and Efficacy of CAR-T in the Treatment of Relapsed / Refractory Non Hodgkin's LymphomaRecruitingNCT04666168Not applicable
- Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Plasma Cell TumorsRecruitingNCT04665076Not applicable
- A Multicenter Clinical Study on the Safety and Effectiveness of CAR-T in the Treatment of Relapsed/Refractory Hodgkin's LymphomaRecruitingNCT04665063Not applicable
- Cord Blood Transplant in Children and Young Adults With Blood Cancers and Non-malignant DisordersRecruitingNCT04644016Phase 2
- First Line Chemotherapy for Classical Hodgkin Lymphoma in Russia (HL-Russia-1)RecruitingNCT04638790Phase 3
- FaR-RMS: An Overarching Study for Children and Adults With Frontline and Relapsed RhabdoMyoSarcomaRecruitingNCT04625907Phase 1/2
- Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) GlioblastomasRecruitingNCT04623931Phase 2
- Clinical Trial of CAR-T in the Treatment of Relapsed and Refractory Hematopoietic and Lymphoid Tissue Tumors in ChildrenRecruitingNCT04610125Not applicable
- Brentuximab Vedotin and Bendamustine for the Treatment of Relapsed or Refractory Follicular LymphomaRecruitingNCT04587687Phase 2
- Haploidentical HCT for Severe Aplastic AnemiaRecruitingNCT04558736Phase 2
- Vaccination With Autologous Dendritic Cells Loaded With Autologous Tumour Homogenate in GlioblastomaRecruitingNCT04523688Phase 2
- Adjuvant Chemotherapy of Three-step Regimen in BRCA1/2 Wide Type Ovarian Cancer (ACTS-2)RecruitingNCT04520074Phase 3
- Study of Pembrolizumab With Bendamustine in Hodgkin LymphomaRecruitingNCT04510636Phase 2
- Apatinib Combined with Temozolomide and Etoposide Capsules in the Treatment of Recurrent Medulloblastoma in ChildrenRecruitingNCT04501718Phase 2
- Pegaspargase-COEP Chemotherapy Combined With Radiotherapy for Extra-nodal NK/T Cell LymphomaRecruitingNCT04484506Phase 2
- Personalized Autologous Transplant for Multiple MyelomaRecruitingNCT04483206Phase 1
- Sequential and Personalized PK-guided Busulfan Administration in the Frame of the Conditiong Regimen for Allo-HSCT in Patients With Malignant Hemopathies Ineligible for the Standard Myeloablative ConditioningNot yet recruitingNCT04451200Phase 2
- Safety and Efficacy of L19TNF Plus Temozolomide Chemoradiotherapy in Patients With Newly Diagnosed GlioblastomaRecruitingNCT04443010Phase 1/2
- Efficacy of Acute Lymphoblastic Leukemia-Based Therapy in Treating Patients With Acute Leukemia of Ambiguous LineageRecruitingNCT04440267Phase 2
- Adjuvant Chemotherapy for Triple Negative Breast Cancer Patients With Residual Disease After Neoadjuvant ChemotherapyRecruitingNCT04437160Phase 2
- CapTemY90 for Grade 2/3 NET Liver MetastasesRecruitingNCT04339036Phase 2
- PIPAC for the Treatment of Peritoneal Carcinomatosis in Patients With Ovarian, Uterine, Appendiceal, Colorectal, or Gastric CancerRecruitingNCT04329494Phase 1
- A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWTRecruitingNCT04322318Phase 2
- CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML)RecruitingNCT04318678Phase 1
- Radiotherapy Versus Radiotherapy Combined With Temozolomide in High-risk Low-grade Gliomas After SurgeryRecruitingNCT04316039Phase 2/3
- Comparing Post-Transplant Cyclophosphamide As GVHD Prophylaxis to Standard of Care for Acute Leukemia PatientsRecruitingNCT04314219Phase 3
- Metronomic Oral Chemotherapy With Cyclophosphamide, Capecitabine and Vinorelbine in Metastatic Breast Cancer PatientsRecruitingNCT04304352Phase 2
- Study of Recombinant Human Endostatin Combined with Temozolomide and Irinotecan in Recurrent GliomasRecruitingNCT04267978Phase 2
- Bortezomib, Isatuximab, Cyclophosphamide and Dexamethasone Induction in Transplant-Eligible Multiple Myeloma Patients With Renal InsufficiencyRecruitingNCT04240054Phase 2
- Regenerative Medicine to Restore Hematopoiesis and Immune Function in Immunodeficiencies and Inherited Bone Marrow FailuresRecruitingNCT04232085Phase 2
- Stem Cell Transplantation in Crohn's DiseaseRecruitingNCT04224558Phase 1/2
- A Study Comparing GLIADEL to Stereotactic Radiosurgery in Metastatic Brain DiseaseRecruitingNCT04222062Phase 2
- High-Risk Neuroblastoma Study 2 of SIOP-Europa-Neuroblastoma (SIOPEN)RecruitingNCT04221035Phase 3
- Implantable Microdevice for the Delivery of Drugs and Their Effect on Tumors in Patients With Metastatic or Recurrent SarcomaRecruitingNCT04199026Not applicable
- GD2 CAR T Cells in Diffuse Intrinsic Pontine Gliomas (DIPG) & Spinal Diffuse Midline Glioma(DMG)RecruitingNCT04196413Phase 1
- Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological MalignanciesRecruitingNCT04195633Phase 2
- BMT-06: Study of Intensity Modulated Total Marrow Irradiation (IM-TMI)RecruitingNCT04187105Phase 2
- Phase II Study of the Effects of Laparoscopic Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Patients With Advanced Gastric CancerRecruitingNCT04107077Phase 2