Alkylating agents: all 3,295 studies that test it

Page 7 of 33. Open to participants first (456), then studies with results posted, then the rest; newest registration first within each.

• Temozolomide Chronotherapy for High Grade GliomaCompletedNCT02781792Phase 2Results posted
• Anti-NY ESO-1 mTCR Peripheral Blood LymphocytesTerminatedNCT02774291Early Phase 1Results posted
• Lymphodepletion and Anti-PD-1 Blockade to Reduce Relapse in AML Patient Not Eligible for TransplantCompletedNCT02771197Phase 2Results posted
• Study Of Single-dose Cyclophosphamide +Pembrolizumab In Patients With Metastatic Triple Negative Breast CancerCompletedNCT02768701Phase 2Results posted
• Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503)CompletedNCT02766465Phase 2Results posted
• A Phase I Trial of Anti-GD2 T-cells (1RG-CART)CompletedNCT02761915Phase 1Results posted
• Transplantation for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone MarrowCompletedNCT02757885Phase 2Results posted
• Early Allogeneic Hematopoietic Cell Transplantation in Treating Patients With Relapsed or Refractory High-Grade Myeloid NeoplasmsCompletedNCT02756572Phase 2Results posted
• Disulfiram/Copper With Concurrent Radiation Therapy and Temozolomide in Patients With Newly Diagnosed GlioblastomaCompletedNCT02715609Phase 1/2Results posted
• Efficacy and Safety of Lanreotide Autogel (ATG) in Combination With Temozolomide in Subjects With Thoracic Neuroendocrine Tumors.CompletedNCT02698410Phase 2Results posted
• The Bladder Instillation Comparison StudyCompletedNCT02695771Phase 3Results posted
• Percutaneous Hepatic Perfusion in Patients With Hepatic-dominant Ocular MelanomaCompletedNCT02678572Phase 3Results posted
• A Study of Olaratumab Alone and in Combination With Standard Chemotherapies in Children With CancerCompletedNCT02677116Phase 1Results posted
• Pharmacokinetic Study of Propylene Glycol-Free Melphalan HCl for Myeloablative Conditioning in Multiple Myeloma Patients Undergoing Autologous TransplantationCompletedNCT02669615Phase 2Results posted
• Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With GlioblastomaCompletedNCT02661282Phase 1/2Results posted
• Cyclophosphamide, Paclitaxel, and Trastuzumab in Treating Stage I-II HER2/Neu Positive Breast Cancer After SurgeryCompletedNCT02654119Phase 2Results posted
• TCR-α/β and CD19 Depleted Stem Cell Grafts From Haplo Donors for HSCT in Relapsed LymphomaCompletedNCT02652468Not applicableResults posted
• R-ICE and Lenalidomide in Treating Patients With First-Relapse/Primary Refractory Diffuse Large B-Cell LymphomaActive, not recruitingNCT02628405Phase 1/2Results posted
• A Phase 2 Study of Eribulin Followed by AC as Preoperative Therapy for HER2-negative Inflammatory Breast CancerActive, not recruitingNCT02623972Phase 2Results posted
• A Study of Haploidentical Bone Marrow Transplant for Patients With Hematologic MalignanciesTerminatedNCT02623439Phase 2Results posted
• High-Dose Weekly Carfilzomib Plus Cyclophosphamide and Dexamethasone in the Treatment of Relapsed Multiple MyelomaCompletedNCT02597062Phase 2Results posted
• Cisplatin and Etoposide Versus Temozolomide and Capecitabine in Patients With Advanced Poorly Differentiated (G3) Non-Small Cell Gastrointestinal Neuroendocrine CarcinomasActive, not recruitingNCT02595424Phase 2Results posted
• Lenalidomide Combined With Vorinostat/Gemcitabine/Busulfan/Melphalan With Autologous Stem-Cell Transplantation in Diffuse Large B-Cell Lymphoma of the ABC SubtypeTerminatedNCT02589145Phase 1/2Results posted
• MT2015-20: Biochemical Correction of Severe EB by Allo HSCT and Serial Donor MSCsCompletedNCT02582775Phase 2Results posted
• Reduced Intensity Conditioning Transplant Using Haploidentical DonorsCompletedNCT02581007Phase 2Results posted
• Combination Chemotherapy With or Without Temsirolimus in Treating Patients With Intermediate Risk RhabdomyosarcomaActive, not recruitingNCT02567435Phase 3Results posted
• Reduced Intensity Chemotherapy and Radiation Therapy Before Donor Stem Cell Transplant in Treating Patients With Hematologic MalignanciesCompletedNCT02566304Phase 2Results posted
• Shorter Course Tacro After NMA, Related Donor PBSCT With High-dose Posttransplant Cy for Hard-to-Engraft MalignanciesCompletedNCT02556931Phase 2Results posted
• Total Therapy for Infants With Acute Lymphoblastic Leukemia (ALL) IActive, not recruitingNCT02553460Phase 1/2Results posted
• A Comparative Study in Chinese Subjects With Chemotherapy Naïve Stage IV Melanoma Receiving Ipilimumab (3 mg/kg) vs. DacarbazineCompletedNCT02545075Phase 3Results posted
• A Study of Rituximab (MabThera) in Participants With Chronic Lymphocytic Leukemia (CLL)CompletedNCT02533401Phase 2Results posted
• Related Hematopoietic Stem Cell Transplantation (HSCT) for Genetic Diseases of Blood CellsTerminatedNCT02512679Phase 2Results posted
• A Two-part Phase IIb Trial of Vigil (Bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) in Ewing's SarcomaCompletedNCT02511132Phase 2Results posted
• Panobinostat, Gemcitabine Hydrochloride, Busulfan, and Melphalan Before Stem Cell Transplant in Treating Patients With Refractory or Relapsed Multiple MyelomaCompletedNCT02506959Phase 2Results posted
• Safety Study of a Helper Peptide Vaccine Plus Adjuvant Combinations for the Treatment of MelanomaTerminatedNCT02425306Phase 1/2Results posted
• Bendamustine, Obinutuzumab, and Dexamethasone in Older Patients With Diffuse Large B-cell LymphomaTerminatedNCT02420210Phase 2Results posted
• Safety and Efficacy of Trastuzumab as Part of Breast Cancer Treatment RegimenCompletedNCT02419742Phase 4Results posted
• Neoadjuvant Study of Two Platinum Regimens in Triple Negative Breast CancerCompletedNCT02413320Phase 2Results posted
• Genetically Modified T Cells in Treating Patients With Stage III-IV Non-small Cell Lung Cancer or MesotheliomaTerminatedNCT02408016Phase 1/2Results posted
• Brain Interstitium Temozolomide Concentration Pre and Post Regadenoson AdministrationCompletedNCT02389738Early Phase 1Results posted
• Fasting on Newly Diagnosed Breast CancerTerminatedNCT02379585Phase 1/2Results posted
• Mitomycin C in Patients With Incurable p16 Positive Oropharyngeal and p16 Negative Head and Neck Squamous Cell Carcinoma (HNSCC) Resistant to Standard TherapiesCompletedNCT02369458Phase 2Results posted
• GVHD Prophylaxis With Post Transplant Cyclophosphamide for Patients With Renal Insufficiency Undergoing a Conventional 8/8 HLA-matched Related or Unrelated Donor Allogeneic Hematopoietic Stem Cell TransplantTerminatedNCT02360111Not applicableResults posted
• Melphalan and Bortezomib Prior to Autologous Stem Cell Transplant in Treating Patients With Multiple MyelomaTerminatedNCT02353572Phase 1/2Results posted
• Bridging Study to Eliminate Presence of MRD for Acute Leukemia Before HCTTerminatedNCT02349178Phase 2Results posted
• Calcineurin Inhibitor-Free Interventions BMT CTN 1301 for Prevention of Graft-versus-Host Disease (BMT CTN 1301)CompletedNCT02345850Phase 3Results posted
• A Phase II Study of Optune (NovoTTF) in Combination With Bevacizumab (BEV) and Temozolomide (TMZ) in Patients With Newly Diagnosed Unresectable Glioblastoma (GBM)TerminatedNCT02343549Phase 2Results posted
• Adult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade GliomasCompletedNCT02343406Phase 2Results posted
• Bioequivalence Study of Temozolomide in Patients With Primary Tumors of the Central Nervous SystemCompletedNCT02343081Phase 4Results posted
• Phase II Study of Combined Temozolomide and SGT-53 for Treatment of Recurrent GlioblastomaTerminatedNCT02340156Phase 2Results posted
• A Study of Obinutuzumab + Bendamustine (BG) in Participants With Previously Untreated Chronic Lymphocytic Leukemia (CLL)CompletedNCT02320487Phase 2Results posted
• Haploidentical Transplant for People With Chronic Granulomatous Disease Using Post Transplant CyclophosphamideTerminatedNCT02282904Phase 1/2Results posted
• Stem Cell Transplantation for Stiff Person Syndrome (SPS)TerminatedNCT02282514Phase 1/2Results posted
• T Cell Receptor Immunotherapy Targeting HPV-16 E6 for HPV-Associated CancersCompletedNCT02280811Phase 1/2Results posted
• A Multi-Center Study of Ibrutinib in Combination With Obinutuzumab Versus Chlorambucil in Combination With Obinutuzumab in Patients With Treatment naïve Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL)CompletedNCT02264574Phase 3Results posted
• Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell LymphomaCompletedNCT02257242Phase 1Results posted
• JAK Inhibitor Before Donor Stem Cell Transplant in Treating Patients With Primary or Secondary MyelofibrosisCompletedNCT02251821Phase 2Results posted
• A Phase II Study of Ibrutinib Plus FCR in Previously Untreated, Younger Patients With Chronic Lymphocytic LeukemiaActive, not recruitingNCT02251548Phase 2Results posted
• Donor Stem Cell Transplant Followed by Cyclophosphamide in Treating Patients With Hematological DiseasesCompletedNCT02248597Phase 2Results posted
• Comparison of the Treatments of Obinutuzumab + Venetoclax Versus Obinutuzumab + Chlorambucil in Patients With Chronic Lymphocytic LeukemiaCompletedNCT02242942Phase 3Results posted
• Combination of Lanreotide Autogel 120mg and Temozolomide in Progressive GEP-NETCompletedNCT02231762Phase 2Results posted
• Brentuximab Vedotin, Ifosfamide, Carboplatin, and Etoposide in Treating Patients With Relapsed or Refractory Hodgkin LymphomaCompletedNCT02227199Phase 1/2Results posted
• Repeat Doses of SB-728mR-T After Cyclophosphamide Conditioning in HIV-Infected Subjects on HAARTCompletedNCT02225665Phase 1/2Results posted
• Transplantation of Partially Mismatched Related or Matched Unrelated Bone Marrow for Patients With Refractory Severe Aplastic AnemiaCompletedNCT02224872Phase 2Results posted
• Bendamustine Hydrochloride, Bortezomib, and Dexamethasone in Treating Patients With Newly Diagnosed Multiple MyelomaCompletedNCT02224729Phase 2Results posted
• Study of T Cells Targeting B-Cell Maturation Antigen for Previously Treated Multiple MyelomaCompletedNCT02215967Phase 1Results posted
• Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive MedulloblastomaTerminatedNCT02212574Early Phase 1Results posted
• Temozolomide 12 Cycles Versus 6 Cycles of Standard First-line Treatment in Patients With Glioblastoma.CompletedNCT02209948Phase 2Results posted
• Novel Approaches for Graft-versus-Host Disease Prevention Compared to Contemporary Controls (BMT CTN 1203)CompletedNCT02208037Phase 2Results posted
• Combined T Cell Depleted Haploidentical Peripheral Blood Stem Cell and Unrelated Umbilical Cord Blood Transplantation in Patients With Hematologic Malignancies Using a Total Lymphoid Irradiation Based Preparative RegimenTerminatedNCT02199041Phase 2Results posted
• IDH1 Peptide Vaccine for Recurrent Grade II GliomaCompletedNCT02193347Phase 1Results posted
• A Study Evaluating the Safety and Efficacy of Venetoclax (GDC-0199) Plus Bendamustine + Rituximab (BR) in Comparison With BR or Venetoclax Plus Rituximab in Participants With Relapsed and Refractory Follicular Non-Hodgkin's Lymphoma (fNHL)CompletedNCT02187861Phase 2Results posted
• Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by SurgeryCompletedNCT02180867Phase 2/3Results posted
• Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade GliomaTerminatedNCT02168270Phase 1Results posted
• Temozolomide With or Without Veliparib in Treating Patients With Newly Diagnosed Glioblastoma MultiformeActive, not recruitingNCT02152982Phase 2/3Results posted
• Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic DiseasesTerminatedNCT02145039Not applicableResults posted
• Cyclophosphamide for Hematopoietic Stem Cell Mobilization in Patients With a Hematologic MalignancyCompletedNCT02139280Phase 2Results posted
• Autologous Stem Cell Transplantation for Patients With Recurrent Nasopharyngeal CarcinomaTerminatedNCT02137096Phase 3Results posted
• UARK 2012-02 Trial For High-Risk Myeloma Evaluating Accelerating and Sustaining Complete RemissionTerminatedNCT02128230Phase 2Results posted
• Myeloablative Haploidentical BMT With Post-transplant Cyclophosphamide for Pediatric Patients With Hematologic MalignanciesCompletedNCT02120157Phase 2Results posted
• A Phase 2 Study of Viagenpumatucel-L (HS-110) in Patients With Non-Small Cell Lung CancerTerminatedNCT02117024Phase 2Results posted
• Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant FailureActive, not recruitingNCT02105766Phase 2Results posted
• Blinatumomab in Treating Younger Patients With Relapsed B-cell Acute Lymphoblastic LeukemiaActive, not recruitingNCT02101853Phase 3Results posted
• Intra-arterial Melphalan in Treating Younger Patients With Unilateral RetinoblastomaCompletedNCT02097134Phase 1Results posted
• Laparoscopic Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) for Metastatic Gastric CancerCompletedNCT02092298Phase 2Results posted
• Nonmyeloablative Conditioning and Transplantation for Patients With Refractory Systemic Lupus Erythematosus (SLE)TerminatedNCT02080195Phase 1/2Results posted
• A Study Evaluating the Efficacy of Obinutuzumab and Bendamustine Treatment in Participants With Refractory or Relapsed Chronic Lymphocytic LeukemiaCompletedNCT02071225Phase 2Results posted
• Post Transplant Cyclophosphamide (Cytoxan) for GvHD ProphylaxisCompletedNCT02065154Phase 2Results posted
• A Study Evaluating the Safety, Efficacy and Pharmacokinetics of Venetoclax Combined With Chemotherapy in Participants With B-Cell Non-Hodgkin's Lymphoma (NHL) and DLBCLCompletedNCT02055820Phase 1/2Results posted
• Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain TumorsCompletedNCT02052648Phase 1/2Results posted
• Total Marrow Irradiation With High Dose Melphalan Prior to Autologous Transplant for Multiple MyelomaTerminatedNCT02043860Phase 1Results posted
• TMI With HD Mel in ASCT for R/R Multiple Myeloma (BMT-03)CompletedNCT02043847Phase 1Results posted
• Efficacy and Safety Study of SyB L-0501 for Patients With Chronic Lymphocytic LeukemiaCompletedNCT02042911Phase 2Results posted
• HIPEC for Peritoneal CarcinomatosisCompletedNCT02040142Phase 2Results posted
• BMT and High Dose Post-Transplant Cyclophosphamide for Chimerism Induction and Renal Allograft ToleranceTerminatedNCT02029638Phase 2Results posted
• CD8+ Antigen-Specific T Cells, Cyclophosphamide, Aldesleukin, and Ipilimumab in Treating Patients With Metastatic MelanomaCompletedNCT02027935Phase 2Results posted
• Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic MedulloblastomaCompletedNCT02017964Phase 2Results posted
• The Effect of Sponge Versus No-Sponge Placement of Mitomycin-C on the Outcomes of Trabeculectomy With Ex-PRESS Glaucoma Filtration DeviceCompletedNCT02016898Phase 2Results posted
• SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCDTerminatedNCT02013375Phase 2Results posted
• Umbilical Cord Blood (UCB) Transplantation in Pediatric Patients With High Risk Leukemia and MyelodysplasiaCompletedNCT02007863Not applicableResults posted

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