Ataxia clinical trials
The registry lists 149 studies for Ataxia across more than 10 countries. 37 are recruiting or about to start. 52 of them are mainly about Ataxia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06. Counting its 4 narrower conditions too, such as Spinocerebellar Ataxias: 320 studies, 73 open.
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Who runs them
Hacettepe University (6) · Columbia University (5) · National Institute of Neurological Disorders and Stroke (NINDS) (4) · Hospices Civils de Lyon (3) · Johns Hopkins University (3) · Cairo University (3) · Augusta University (2) · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (2)
What is being tested here
Drugs under test in Ataxia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest, phase 3 first
- May 2027A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 Gene · Phase 3 · Assistance Publique - Hôpitaux de Paris
- Dec 2026Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia · IRCCS Eugenio Medea
- Dec 2026RFC1 Natural History Study · Prof. Dr. Matthis Synofzik
- Jan 2027Fecobionics in Biofeedback Therapy in Dyssynergia Patients · The California Medical Innovations Institute, Inc.
- Feb 2027Effects of Transcranial Direct Current Stimulation Associated With Neurofunctional Rehabilitation in Individuals With Spinocerebellar Ataxias · Federal University of Health Science of Porto Alegre
- Apr 2027Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical Study · Washington University School of Medicine
- May 2027Aprepitant for the Treatment of CLIFAHDD · The University of Texas Health Science Center at San Antonio
- Jun 2027Can Acute Photobiomodulation Improve Balance and Cognition in Individuals With Ataxia: a Pilot Feasibility Placebo Randomized Controlled Trial. · University of Central Lancashire
- Jun 2027Balance Rehabilitation With Modified Visual Input in Patients With Neuropathy · Assistance Publique - Hôpitaux de Paris
- Jul 2027Digital Patient Engagement in Technology-Supported Neurorehabilitation · Catholic University, Italy
Who these studies take
Of the 28 Ataxia studies recruiting now, 13 (46%) set no upper age limit and 12 (43%) stop at 75 or younger. 15 (54%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 9 (32%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 13 (46%) | 13 (46%) |
| 18 | 25 (89%) | 25 (89%) |
| 30 | 25 (89%) | 25 (89%) |
| 40 | 25 (89%) | 25 (89%) |
| 50 | 24 (86%) | 24 (86%) |
| 65 | 22 (79%) | 22 (79%) |
| 75 | 21 (75%) | 21 (75%) |
| 85 | 14 (50%) | 14 (50%) |
Across all 149 studies, recruiting or not: 46% stop at 75 or younger and 35% at 65; 42% take children; 4% are for women only and 1% for men only; 26% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Ataxia studies take
Of 55 interventional studies with no phase under Ataxia, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 19 mo7–33 · 55 studies | — | 19 mo7–34 · 53 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 149. Browse all 149 → or search them.
- A Study of SGT-212 Gene Therapy in Friedreich's AtaxiaRecruitingNCT07180355Phase 11 country
- Aprepitant for the Treatment of CLIFAHDDRecruitingNCT07845825Early Phase 11 country
- Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at SanfordRecruitingNCT017931681 country
- At Home Use of Stimulation Suits for Managing MS SymptomsRecruitingNCT07202195Not applicable2 countries
- Biomarkers in Friedreich's AtaxiaRecruitingNCT024975341 country
- Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's AtaxiaRecruitingNCT05302271Phase 11 country
- Can Acute Photobiomodulation Improve Balance and Cognition in Individuals With Ataxia: a Pilot Feasibility Placebo Randomized Controlled Trial.Not yet recruitingNCT07296068Not applicable1 country
- Home Exercise for Individuals With Neurodegenerative DiseaseRecruitingNCT05443906Not applicable1 country
- Digital Patient Engagement in Technology-Supported NeurorehabilitationNot yet recruitingNCT077940721 country
- Prospective Natural History Study of POLG DiseaseRecruitingNCT077758729 countries
- Friedreich Ataxia Global Clinical Consortium UNIFIED Natural History StudyRecruitingNCT0601694617 countries
- Transplantation of Human iPS Cell-derived Dopaminergic Progenitors (CT1-DAP001) for Parkinson's Disease (Phase I/II)RecruitingNCT06482268Phase 11 country
- Characterization of the Cardiac Phenotype of Friedreich's Ataxia (FRDA)RecruitingNCT023163141 country
- Impact of Foot Orthoses on Gait in Individuals With AtaxiaRecruitingNCT07720700Not applicable1 country
- Balance Rehabilitation With Modified Visual Input in Patients With NeuropathyRecruitingNCT03881930Not applicable1 country
- Bilateral Anodal Cerebellar tDCS for Multidomain Dysfunctions in Patients With Multiple SclerosisNot yet recruitingNCT07555379Not applicable1 country
- Spinocerebellar Ataxia Type 27B Natural History Study (SCA27B-NHS)RecruitingNCT064725574 countries
- RFC1 Natural History StudyRecruitingNCT051778097 countries
- Vibrotactile Balance Belt Effect on Improving GaitRecruitingNCT07253532Not applicable1 country
- A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia SyndromesRecruitingNCT065856051 country
- Evaluation of the Safety and Preliminary Efficacy of Neuroinduced Mesenchymal Stem Cells and Exosome Therapy in Patients With Spinocerebellar PalsyNot yet recruitingNCT07467733Phase 1/21 country
- Effects of Cerebellar tACS-iTBS in AtaxiaRecruitingNCT06420271Not applicable1 country
- Sensori-motor and Perceptual Functions of the PPC.RecruitingNCT03286686Not applicable1 country
- Wolfram Syndrome and WFS1-related Disorders International Registry and Clinical StudyRecruitingNCT028415531 country
- A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 GeneRecruitingNCT07185347Phase 31 country
- Fecobionics in Biofeedback Therapy in Dyssynergia PatientsRecruitingNCT05807321Not applicable1 country
- Registry and Natural History of Epilepsy-Dyskinesia SyndromesRecruitingNCT069677271 country
- Structural Validity and Inter-rater Reliabitiliy of the Ataxia Trunk, Lower And Upper Extremity Scale (ATLAS)Not yet recruitingNCT07079332
- Home-based Gait and Balance Training in Patients With Movement DisordersRecruitingNCT06617884Not applicable1 country
- Neuroimmunology Registry and BiobankRecruitingNCT069583411 country
- Dentatorubral-pallidoluysian Atrophy Natural History and Biomarkers StudyRecruitingNCT062731502 countries
- Ataxia-telangiectasia: Treating Mitochondrial Dysfunction With Nicotinamide RibosideNot yet recruitingNCT06324877Not applicable1 country
- Rehabilitation Program on Genetic and Degenerative AtaxiaNot yet recruitingNCT06089863Not applicable1 country
- Home-based Complex Intervention for Children With Ataxia TelangiectasiaRecruitingNCT05692622Not applicable1 country
- Effects of a Multimodal Exercise Program for Children With ASDNot yet recruitingNCT05509231Not applicable
- Longitudinal Tracking of Patients Diagnosed With Neurodegenerative Movement DisordersRecruitingNCT054868061 country
- European Registry on Rare Neurological DiseasesNot yet recruitingNCT04319796
- Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's AtaxiaActive, not recruitingNCT06692296Not applicable1 country
- Motor-Cognitive Training , Cognitive Performance and BalanceCompletedNCT07045922Not applicable1 country
- Assistive Devices and Gait in Persons With AtaxiaCompletedNCT06866353Not applicable1 country
- Balloon Inflation in BiofeedbackCompletedNCT07705542Not applicable1 country
- Sirolimus Treatment in Pediatric Patients With Ataxia-TelangiectasiaCompletedNCT07820579Phase 21 country
- High-Dose Ambroxol in Pediatric Type III Gaucher Disease (GD3)CompletedNCT07285369Not applicable1 country
- A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDGActive, not recruitingNCT06892288Phase 2/310 countries
- Perceptual Decision Making Under Conditions of Visual UncertaintyWithdrawnNCT01845883Not applicable1 country
- Robotic Neurorehabilitation in Patients With AtaxiaActive, not recruitingNCT07733687Not applicable1 country
- Cawthorne-Cooksey Exercises and Frenkel Exercises on Balance and Coordination in StrokeCompletedNCT07724860Not applicable1 country
- Effect of GMI With and Without NM on LE in Cancer Patients With CIPNCompletedNCT07712302Not applicable1 country
- "Evaluation of Usability and Safety of the Self-balancing Walking System Atalante in Patients With Multiple Sclerosis"CompletedNCT05563402Not applicable1 country
- Troriluzole in Adult Participants With Spinocerebellar AtaxiaActive, not recruitingNCT03701399Phase 32 countries