Urolithiasis clinical trials
The registry lists 253 studies for Urolithiasis across more than 10 countries. 67 are recruiting or about to start. 127 of them are mainly about Urolithiasis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05. Counting its 5 narrower conditions too, such as Kidney Calculi: 964 studies, 254 open.
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Status
Who runs them
The First Affiliated Hospital of Guangzhou Medical University (10) · Mansoura University (9) · Guohua Zeng (6) · Ain Shams University (5) · University of Alabama at Birmingham (5) · Calyxo, Inc. (5) · University of Texas Southwestern Medical Center (4) · St. Petersburg State Pavlov Medical University (4)
What is being tested here
Drugs under test in Urolithiasis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Acupressure as Complementary Analgesia in Shock Wave Lithotripsy · Medipol University
- Dec 2026Clinical Evaluation of the Pelvic Floor Fatigue Index (PFFI) · Trabzon Kanuni Education and Research Hospital
- Dec 2026A Retrospective, Multi-center Real-world Study of Steerable Ureteroscopic Renal Evacuation (SURE) Procedure With the CVAC® System · Calyxo, Inc.
- Dec 2026A Study on the Application of NE Irrigation Fluid for Hemostasis in Flexible Ureteroscopic Lithotripsy: A Prospective Single-arm Interventional Study of Upper Urinary Tract Calculi.(NE: Norepinephrine) · Geriatric Hospital of Nanjing Medical University
- Dec 2026Evaluation of the Safety and Performance of the Hydrustent® Biodegradable Hydrogel Ureteral Stent · Hydrumedical
- Jan 2027Pain Control During ESWL Using Non-Opioid Analgesics · University of Gaziantep
- Jan 2027FANS-FURS vs Suction Mini-PCNL for 2-3 cm Renal Stones: A Multicenter Randomized Trial · Mansoura University
- Jan 20272D:4D Digit Ratio and Urinary Stone Disease · Emrah Kızılay
- Feb 2027Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRS · Hitit University
- Mar 2027Human Voice vs AI-Cloned Voice Audio Added to Written Consent Before Ureteroscopy or Retrograde Intrarenal Surgery (AUDIO-CONSENT) · Aydin Adnan Menderes University
Who these studies take
Of the 39 Urolithiasis studies recruiting now, 18 (46%) set no upper age limit and 13 (33%) stop at 75 or younger. 5 (13%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 5 (13%) | 5 (13%) |
| 18 | 35 (90%) | 35 (90%) |
| 30 | 34 (87%) | 34 (87%) |
| 40 | 35 (90%) | 35 (90%) |
| 50 | 35 (90%) | 35 (90%) |
| 65 | 32 (82%) | 32 (82%) |
| 75 | 29 (74%) | 29 (74%) |
| 85 | 20 (51%) | 20 (51%) |
Across all 253 studies, recruiting or not: 30% stop at 75 or younger and 18% at 65; 15% take children; 0% are for women only and 2% for men only; 17% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Urolithiasis studies take
Of 96 interventional studies with no phase under Urolithiasis, half reached primary completion within 19 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 19 mo11–39 · 96 studies | — | 20 mo11–40 · 86 studies |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 11, 2026.
Started recruiting1
- Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence StudyNov 2, 2026NCT07155005
Stopped1
- Multiomics Biomarkers for UrolithiasisTerminatedOct 22, 2026NCT05452291
Newly registered4
- Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging StudyNov 3, 2026NCT07913178
- Intertransverse Process Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Percutaneous NephrolithotomyNov 2, 2026NCT07908992
- TZ-RIRS vs. C-RIRS for Kidney StonesOct 30, 2026NCT07906964
- Acupressure as Complementary Analgesia in Shock Wave LithotripsyOct 21, 2026NCT07885696
Studies
Recruiting first, then most recently updated. Showing 50 of 253. Browse all 253 → or search them.
- Renal Structural and Functional Alterations Following Repeated Ureteroscopic Procedures: An Exploratory Multimodal Imaging StudyEnrolling by invitationNCT079131781 country
- Stone Clearance With Aspiration vs Other Technologies: a Real-world Evidence StudyRecruitingNCT071550051 country
- Intertransverse Process Block Versus Erector Spinae Plane Block for Postoperative Analgesia After Percutaneous NephrolithotomyNot yet recruitingNCT07908992Not applicable1 country
- Supervised Endoscopic Tele-controlled Intelligent LithotripsyRecruitingNCT07411391Not applicable1 country
- Trial of Ureteroscopy vs Steerable Continuous Flow Aspiration TechnologyRecruitingNCT07101809Not applicable1 country
- Renal Stone Treatment Global RegistryRecruitingNCT052973311 country
- Acupressure as Complementary Analgesia in Shock Wave LithotripsyRecruitingNCT07885696Not applicable1 country
- Gut Oxalate Absorption in Calcium Oxalate Stone DiseaseRecruitingNCT06331546Not applicable1 country
- O. Formigenes Colonization in Calcium Oxalate Kidney Stone DiseaseRecruitingNCT06330246Not applicable1 country
- Comparison of Two Versus Four Weeks of Ureteral Stenting Prior to Ureteroscopy After Failed Primary Ureteral AccessEnrolling by invitationNCT07868874Not applicable1 country
- Human Voice vs AI-Cloned Voice Audio Added to Written Consent Before Ureteroscopy or Retrograde Intrarenal Surgery (AUDIO-CONSENT)RecruitingNCT07859436Not applicable1 country
- Assessment of Urinary Microplastic Concentration in Patients With Urolithiasis: A Prospective Case-Control StudyNot yet recruitingNCT07841834
- Real-World Study of Obstructive Upper Urinary Tract Stones and Acute PyelonephritisNot yet recruitingNCT07816991
- Transurethral Versus Percutaneous Cystolithotripsy for Bladder Stones in AdultsNot yet recruitingNCT07810582Not applicable
- Endogenous Oxalate Synthesis in Idiopathic Calcium Oxalate Kidney Stone DiseaseRecruitingNCT06989320Not applicable1 country
- A Study on the Application of NE Irrigation Fluid for Hemostasis in Flexible Ureteroscopic Lithotripsy: A Prospective Single-arm Interventional Study of Upper Urinary Tract Calculi.(NE: Norepinephrine)RecruitingNCT07786844Phase 1/21 country
- Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented PatientsRecruitingNCT077677731 country
- Clinical Evaluation of the Pelvic Floor Fatigue Index (PFFI)RecruitingNCT077636131 country
- Pain Control During ESWL Using Non-Opioid AnalgesicsNot yet recruitingNCT07512297Phase 41 country
- Predicting the Success of Flexible Ureterorenoscopy for Kidney and Upper Ureter StonesNot yet recruitingNCT07753096
- DISON I - Directly Integrated Suction and Optics System for the Treatment of NephrolithiasisNot yet recruitingNCT07712861Not applicable5 countries
- Comparison of Ureteral Stent Designs in Children With Kidney StonesRecruitingNCT07742358Not applicable1 country
- 2D:4D Digit Ratio and Urinary Stone DiseaseNot yet recruitingNCT077369241 country
- Effects of Virtual Reality Education on Anxiety and Learning in Patients Undergoing Urolithiasis SurgeryRecruitingNCT07620873Not applicable1 country
- COMPARISON OF FANS VS CONVENTIONAL URETERAL ACCESS SHEATH in RIRS on POSTOPERATIVE ACUTE KIDNEY INJURYRecruitingNCT07685587Not applicable1 country
- Access Sheaths With Aspiration for Renal RetrOgrade Surgery, Randomized CompArative OutcomesNot yet recruitingNCT07678255Not applicable1 country
- PMCF Investigation of MODULITH® SLX-F2 With StorM-Track in Patients With Kidney StonesRecruitingNCT07272720Not applicable1 country
- Antibiotic Irrigation and Suction Ureteral Access Sheath in RIRSRecruitingNCT07655050Not applicable1 country
- ComfiJ Versus Conventional Double-J Stent for Ureteral Stent SymptomsRecruitingNCT07627828Not applicable1 country
- Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary StonesRecruitingNCT06003348Phase 41 country
- L-Citrulline Versus Tamsulosin for Medical Expulsive Therapy of Distal Ureteral StonesRecruitingNCT07617909Phase 21 country
- Intra-nasal Ketorolac for Acute Ureteral Stent-associated Pain Following Ureteroscopy for Stone DiseaseRecruitingNCT06158620Phase 1/21 country
- Evaluation of the Safety and Performance of the Hydrustent® Biodegradable Hydrogel Ureteral StentRecruitingNCT06719089Not applicable1 country
- Antibiotic Prophylaxis for Ureteroscopy With a Negative Pressure Suction SheathRecruitingNCT07246967Not applicable1 country
- Relief Efficacy of Lidocaine Versus Morphine for Acute Renal Colic in the Emergency DepartmentNot yet recruitingNCT07536594Not applicable
- Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney StonesNot yet recruitingNCT07408076Phase 1/23 countries
- Pilot Study to Evaluate the Contribution of Gene Variants to Idiopathic UrolithiasisEnrolling by invitationNCT011278541 country
- Optical Motion Capture-Assisted Ultrasound for Pediatric ESWLNot yet recruitingNCT07299032Not applicable1 country
- FANS-FURS vs Suction Mini-PCNL for 2-3 cm Renal Stones: A Multicenter Randomized TrialNot yet recruitingNCT07295860Not applicable1 country
- Risk Factors for Postoperative Fever and Sepsis Following Retrograde Intrarenal SurgeryNot yet recruitingNCT072959251 country
- Evaluation of Quality of Life in Patients After Placement of a Modified Double J Ureteral StentRecruitingNCT07275879Not applicable1 country
- Comparison of Extracorporeal Shock Wave Lithotripsy Versus Retrograde Intrarenal Surgery in the Management of Renal CalculiRecruitingNCT07261995Not applicable1 country
- A Single-Center Clinical Study on the Efficacy and Safety of VISORRecruitingNCT07071948Not applicable1 country
- Retrolaminar Block Analgesia and Patient Comfort During Prone ESWLNot yet recruitingNCT071776251 country
- Safety and Effectiveness of Antegrade Flexible Ureteroscopy-Assisted Percutaneous Nephrolithotomy for Staghorn CalculiNot yet recruitingNCT07172373Not applicable
- Registry of MIUS for Urolithiasis (ReMIUS-U)Enrolling by invitationNCT063949081 country
- The Use of AR / VR in Patients Presenting to the ED With Renal ColicRecruitingNCT07070401Not applicable1 country
- Efficacy of Dietary Interventions and Educational Programs as Adjunctive Therapies for the Management of Urolithiasis: Efficacy of Fresh Lemon Juice and Roselle as Educational Program on Urolithiasis ParametersNot yet recruitingNCT07047742Not applicable1 country
- ButOx Human Trial: An Open Label Prospective Cohort Study to Investigate the Effect of Tributyrin (Butyrate Precursor Molecule) Supplementation on Markers of Calcium Oxalate NephrolithiasisNot yet recruitingNCT07004257Not applicable1 country
- ILY Robotic System vs Manual Flexible Ureteroscopy for Kidney Stone TreatmentRecruitingNCT06996587Not applicable1 country